Definitive Hematopoiesis in the Yolk Sac Emerges from Wnt-Responsive Hemogenic Endothelium Independently of Circulation and Arterial Identity

Stem Cells

Volumn 34, Issue 2, 2016, Pages 431-444

  Frame, Jenna M ^a   Fegan, Katherine H ^a   Conway, Simon J ^b   McGrath, Kathleen E ^a   Palis, James ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Embryo; Endothelial cell; Hemangioblast; Hematopoiesis; Hematopoietic progenitors; Hematopoietic stem cells; Vascular development

Indexed keywords

BETA CATENIN; CD16 ANTIGEN; CD32 ANTIGEN; CD45 ANTIGEN; FIBRINOGEN RECEPTOR; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR RUNX1; TRANSCRIPTION FACTOR SOX17; TRANSCRIPTION FACTOR TAL1; VASCULAR ENDOTHELIAL CADHERIN; VASCULOTROPIN RECEPTOR 2; WNT PROTEIN;

ADULT; ANGIOGENESIS; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL POPULATION; CELL STRUCTURE; EMBRYO; ERYTHRO MYELOID PROGENITOR; ERYTHROBLAST; GRANULOCYTE; HEMANGIOBLAST; HEMATOPOIESIS; IMMUNOPHENOTYPING; IN VITRO STUDY; MACROPHAGE; MEGAKARYOCYTE; MOUSE; MYELOID PROGENITOR CELL; NONHUMAN; SPATIOTEMPORAL ANALYSIS; UPREGULATION; VASCULAR REMODELING; WNT SIGNALING PATHWAY; YOLK SAC; ANIMAL; CYTOLOGY; EXTRAMEDULLARY HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; METABOLISM; PHYSIOLOGY; TRANSGENIC MOUSE; VASCULAR ENDOTHELIUM; VASCULARIZATION;

ANIMALS; ENDOTHELIUM, VASCULAR; HEMATOPOIESIS, EXTRAMEDULLARY; HEMATOPOIETIC STEM CELLS; MICE; MICE, TRANSGENIC; WNT PROTEINS; YOLK SAC;

EID: 84958157404     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.2213     Document Type: Article

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