Osteoclast-primed Foxp3+ CD8 t cells induce t-bet, eomesodermin, and ifn-γ to regulate bone resorption

Journal of Immunology

Volumn 197, Issue 3, 2016, Pages 726-735

  Shashkova, Elena V ^a   Trivedi, Jahnavi ^a   Cline Smith, Anna B ^a   Ferris, Chloe ^a   Buchwald, Zachary S ^a   Gibbs, Jesse ^b   Novack, Deborah ^b   Aurora, Rajeev ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EOMESODERMIN; GAMMA INTERFERON; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; OSTEOCLAST DIFFERENTIATION FACTOR; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR T BET; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; EOMES PROTEIN, MOUSE; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; T BOX TRANSCRIPTION FACTOR; T-BOX TRANSCRIPTION FACTOR TBX21;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CD8+ T LYMPHOCYTE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; IN VIVO STUDY; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY T LYMPHOCYTE; ANIMAL; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; BIOSYNTHESIS; BONE DEVELOPMENT; C57BL MOUSE; CELL DIFFERENTIATION; FLOW CYTOMETRY; IMMUNOLOGY; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; METABOLISM; PHYSIOLOGY; POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; ANTIGEN PRESENTATION; ANTIGEN-PRESENTING CELLS; BLOTTING, WESTERN; BONE RESORPTION; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; INTERFERON-GAMMA; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NF-KAPPA B; OSTEOCLASTS; OSTEOGENESIS; POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; T-BOX DOMAIN PROTEINS;

EID: 84979578341     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1600253     Document Type: Article

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