Modulation in vitro of keratinocyte integrins by interferon-α and interferon-γ

International Journal of Dermatology

Volumn 41, Issue 12, 2002, Pages 836-840

  Tenaud, Isabelle ^a   Leroy, Sabine ^a   Chebassier, Nathalie ^a   Dréno, Brigitte ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA3 INTEGRIN; ALPHA5 INTEGRIN; ALPHA6 INTEGRIN; BETA1 INTEGRIN; BETA4 INTEGRIN; CD51 ANTIGEN; INTEGRIN; RECOMBINANT ALPHA2A INTERFERON; RECOMBINANT GAMMA INTERFERON; UNCLASSIFIED DRUG;

ALPHA CHAIN; BULLOUS SKIN DISEASE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONFERENCE PAPER; CONTROLLED STUDY; CULTURE MEDIUM; DRUG MECHANISM; DRUG USE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOMODULATION; IN VITRO STUDY; KERATINOCYTE; LONG TERM CARE; MEMBRANE RECONSTITUTION; METHODOLOGY; MONOLAYER CULTURE; PROTEIN EXPRESSION; PROTEIN INDUCTION; SKIN; STATISTICAL SIGNIFICANCE;

ANTIGENIC MODULATION; BIOLOGICAL RESPONSE MODIFIERS; CELL DIFFERENTIATION; HUMANS; INTEGRIN ALPHA2BETA1; INTEGRIN ALPHA3BETA1; INTEGRIN ALPHA5BETA1; INTEGRIN ALPHA6BETA4; INTEGRINS; INTERFERON-ALPHA; KERATINOCYTES; RECEPTORS, VITRONECTIN; TIME FACTORS;

EID: 0036938149     PISSN: 00119059     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-4362.2002.01598.x     Document Type: Conference Paper

References (23)

1. Hynes RO. Integrins: Versatility, modulation, and signaling in cell adhesion. Cell 1992; 69: 11-25.
2. Hertle MD, Adams JC, Watt FM. Integrin expression during human epidermal development in vivo and in vitro. Development 1991; 112: 193-206.
3. Hotchin NA, Gandarillas A, Watt FM. Regulation of cell surface β1 integrin levels during keratinocyte terminal differentiation. J Cell Biol 1995; 128: 1209-1219.
4. Carter WG, Wayner EA, Bouchard TS, Kaur P. The role of integrins α2β1 and α3β1 in cell-cell and cell-substrate adhesion of human epidermal cells. J Cell Biol 1990; 110: 1387-1404.
5. Grzesiak JJ, Pierschbacher MD. Changes in the concentrations of extracellular Mg++ and Ca++ down-regulate E-cadherin and up-regulate α2β1 integrin function, activating keratinocyte migration on type I collagen. J Invest Dermatol 1995; 104: 768-774.
6. Hotchin NA, Watt FM. Transcriptional and post-translational regulation of β1 integrin expression during terminal keratinocyte terminal differentiation. J Biol Chem 1992; 267: 14852-14858.
7. Watt FM, Jones P. Expression and function of the keratinocyte integrins. Development 1993; (Suppl.): 185-192.
8. Saunders N, Dahler A, Jones S, et al. Interferon-γ as a regulator of squamous differentiation. J Dermatol Sci 1996; 13: 98-106.
9. Nickoloff BJ, Mahrle G, Morhenn VB. Ultrastructural effects recombinant gamma interferon on cultured human keratinocyte. J Utrastruct Res 1986: 10: 17-21.
10. Saunders NA, Jetten AM. Control of growth regulatory and differentiation-specific genes in human epidermal keratinocytes by interferon-γ Antagonism by retinoid acid and transforming growth factor β1. J Biol Chem 1994; 269: 2016-2022.
11. Hachisuka H, Okubo K, Karashima T, Sasai Y. Increase of DNA synthesis and expression of bullous pemphigoid antigen on normal human keratinocytes by addition of interferons. J Invest Dermatol 1989; 93: 554-555.
12. Tamai K, Li K, Silos S, et al. Interferon-γ mediated inactivation of transcription of the 230-kDa Bullous Pemphigoid Antigen Gene (BPAG1) provides novel insight into keratinocyte differentiation. J Biol Chem 1995; 270: 392-396.
13. Stadler R, Muller R, Orfanos CE. Effect of recombinant alpha A-interferon on DNA synthesis and differentiation of human keratinocytes in vitro. Br J Dermatol 1986; 114 273-277.
14. Prunieras M. Epidermal cell cultures as models for living epidermis. J Invest Dermatol 1979; 73: 135-137.
15. Basset-Seguin N, Culard JF, Kerai C, et al. Reconstituted skin in culture: A simple method with optimal differentiation. Differentiation 1990; 44: 232-238.
16. Hertle MD, Jones PH, Groves RW, et al. Integrins expression by human epidermal keratinocytes can be modulated by interferon-γ, transforming growth factor-β, tumor necrosis factor-α, and culture on a dermal equivalent. J Invest Dermatol 1995; 104: 260-265.
17. Kashihara-Sawami M, Norris DA. The state of differentiation of cultured human kiratinocytes determines the level of intercellular adhesion molecule-1 (ICAM-1) expression induced by γ interferon. J Invest Dermatol 1992; 98: 741-747.
18. Griffiths CE, Voorhees JJ, Nickoloff BJ. Gamma interferon induces different keratinocyte cellular patterns of expression of HLA-DR and DQ and intercellular adhesion molecule-1 (ICAM-1) antigens. Br J Dermatol 1989; 120: 1-7.
19. 44 expression by tumour necrosis factor-alpha is neutralized by interleukin-10 in Langerhans cells. J Invest Dermatol 1995; 105: 124-127.
20. Arany I, Brysk MM, Brysk H, Tyring SK. Regulation of inducible nitric oxide synthase mRNA levels by differentiation and cytokines in human keratinocytes. Biochem Biophys Res Comm 1996; 220: 618-622.
21. Boukhelifa M, Paulin Y, Font J, et al. Integrins of the β1 family influence keratinocyte-lymphocyte interactions. J Invest Dermatol 1998; 11: 650-655.
22. Georges-Labouesse E, Messaddeq N, Yehia G, et al. Absence of integrin α6 leads to epidermolysis bullosa and neonatal death in mice. Nat Genet 1996; 13: 370-373.
23. 3β1 integrin is required for normal development of the epidermal basement membrane zone. J Cell Biol 1997; 137: 729-732.