Identifying novel cancer therapies using chemical genetics and zebrafish

Advances in Experimental Medicine and Biology

Volumn 916, Issue , 2016, Pages 103-124

  Dang, Michelle ^a,b   Fogley, Rachel ^a,b   Zon, Leonard I ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Cancer; Chemical genetics; Chemical screen; Drug discovery; Therapeutics; Zebrafish

Indexed keywords

BREQUINAR; CYCLIN B1; HISTONE H3; LEFLUNOMIDE; MITOGEN ACTIVATED PROTEIN KINASE; MYC PROTEIN; N [3 (5 CHLORO 1H PYRROLO[2,3 B]PYRIDINE 3 CARBONYL) 2,4 DIFLUOROPHENYL]PROPANESULFONAMIDE; PROTEIN BAD; PROTEIN KINASE B; PROTEIN P70; TERIFLUNOMIDE;

ACUTE LYMPHOBLASTIC LEUKEMIA; BIOTECHNOLOGICAL PROCEDURES; CANCER GENETICS; CANCER STEM CELL; CANCER THERAPY; CELL CYCLE PROGRESSION; CELL SELECTION; CHEMICAL ANALYSIS; CHEMICAL GENETICS; EMBRYO DEVELOPMENT; FLUORESCENCE ACTIVATED CELL SORTING; FLUORESCENCE IMAGING; GENE EXPRESSION; GENE IDENTIFICATION; HIGH THROUGHPUT SCREENING; HUMAN; IN SITU HYBRIDIZATION; MELANOMA; MICROARRAY ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; ZEBRA FISH; ANIMAL; DISEASE MODEL; DRUG SCREENING; GENETICS; NEOPLASMS; PATHOLOGY;

ANIMALS; DISEASE MODELS, ANIMAL; DRUG SCREENING ASSAYS, ANTITUMOR; NEOPLASMS; ZEBRAFISH;

EID: 84979055682     PISSN: 00652598     EISSN: 22148019     Source Type: Book Series    
DOI: 10.1007/978-3-319-30654-4_5     Document Type: Chapter

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