Automated zebrafish chorion removal and single embryo placement: Optimizing Throughput of zebrafish developmental toxicity screens

Journal of Laboratory Automation

Volumn 17, Issue 1, 2012, Pages 66-74

  Mandrell, David ^a   Truong, Lisa ^a   Jephson, Caleb ^a   Sarker, Mushfiqur R ^a   Moore, Aaron ^a   Lang, Christopher ^a   Simonich, Michael T ^a   Tanguay, Robert L ^a  

^a OREGON STATE UNIVERSITY   (United States)

Author keywords

Automation; Chorion; Robotic; Zebrafish

Indexed keywords

AUTOMATION;

CHORION; DEVELOPMENTAL TOXICITY; DRUG DISCOVERY; EMBRYO MORTALITIES; POST-FERTILIZATION; STATISTICAL DIFFERENCES; ZEBRAFISH; ZEBRAFISH EMBRYOS;

ROBOTICS;

ARTICLE; AUTOMATION; CHORION; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DEVELOPMENTAL TOXICITY; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO MORTALITY; EMBRYO TRANSFER; INTERMETHOD COMPARISON; ISOLATION PROCEDURE; NONHUMAN; PROCESS OPTIMIZATION; ROBOTICS; ZEBRA FISH; ANIMAL; DRUG DEVELOPMENT; DRUG EFFECT; DRUG SCREENING; HIGH THROUGHPUT SCREENING; INSTRUMENTATION; LABORATORY AUTOMATION; METABOLISM; METHODOLOGY; TOXICITY TESTING;

ANIMALS; AUTOMATION, LABORATORY; CHORION; DRUG DISCOVERY; DRUG EVALUATION, PRECLINICAL; EMBRYONIC DEVELOPMENT; HIGH-THROUGHPUT SCREENING ASSAYS; ROBOTICS; SINGLE EMBRYO TRANSFER; TOXICITY TESTS; ZEBRAFISH;

EID: 84864773810     PISSN: 22110682     EISSN: 22110690     Source Type: Journal    
DOI: 10.1177/2211068211432197     Document Type: Article

References (18)

1. Hartung, T. Lessons Learned from Alternative Methods and Their Validation for a New Toxicology in the 21st Century. J. Toxicol. Environ. Health B Crit. Rev. 2010, 13(2-4), 277-290.
2. Schmidt, C. W. TOX 21: New Dimensions of Toxicity Testing. Environ. Health Perspect. 2009, 117(8), A348-A353.
3. Lilienblum, W.; Dekant, W.; Foth, H.; Gebel, T.; Hengstler, J. G.; Kahl, R.; Kramer, P. J.; Schweinfurth, H.; Wollin, K. M. Alternative Methods to Safety Studies in Experimental Animals: Role in the Risk Assessment of Chemicals under the New European Chemicals Legislation (REACH). Arch. Toxicol. 2008, 82(4), 211-236.
4. Zon, L. I.; Peterson, R. T. In Vivo Drug Discovery in the Zebrafish. Nat. Rev. Drug Discov. 2005, 4(1), 35-44.
5. Sukardi, H.; Chng, H. T.; Chan, E. C.; Gong, Z.; Lam, S. H. Zebrafish for Drug Toxicity Screening: Bridging the In Vitro Cell-Based Models and In Vivo Mammalian Models. Expert Opin. Drug Metab. Toxicol. 2011, 7(5), 579-589.
6. Zon, L. I.; Peterson, R. The New Age of Chemical Screening in Zebrafish. Zebrafish 2010, 7(1), 1.
7. Kokel, D.; Bryan, J.; Laggner, C.; White, R.; Cheung, C. Y.; Mateus, R.; Healey, D.; Kim, S.; Werdich, A. A.; Haggarty, S. J.; et al. Rapid Behavior-Based Identification of Neuroactive Small Molecules in the Zebrafish. Nat. Chem. Biol. 2010, 6(3), 231-237.
8. Paik, E. J.; de Jong, J. L.; Pugach, E.; Opara, P.; Zon, L. I. A Chemical Genetic Screen in Zebrafish for Pathways Interacting with cdx4 in Primitive Hematopoiesis. Zebrafish 2010, 7(1), 61-68.
9. Rihel, J.; Prober, D. A.; Arvanites, A.; Lam, K.; Zimmerman, S.; Jang, S.; Haggarty, S. J.; Kokel, D.; Rubin, L. L.; Peterson, R. T.; et al. Zebrafish Behavioral Profiling Links Drugs to Biological Targets and Rest/Wake Regulation. Science 2010, 327(5963), 348-351.
10. Wang, C.; Tao, W.; Wang, Y.; Bikow, J.; Lu, B.; Keating, A.; Verma, S.; Parker, T. G.; Han, R.; Wen, X. Y. Rosuvastatin, Identified from a Zebrafish Chemical Genetic Screen for Antiangiogenic Compounds, Suppresses the Growth of Prostate Cancer. Eur. Urol. 2010, 58(3), 418-426.
11. Yen, J.; Donerly, S.; Levin, E. D.; Linney, E. A. Differential Acetyl cholinesterase Inhibition of Chlorpyrifos, Diazinon and Parathion in Larval Zebrafish. Neurotoxicol. Teratol. 2011, 33(6), 735-741.
12. Johnson, A.; Carew, E.; Sloman, K. A. The Effects of Copper on the Morphological and Functional Development of Zebrafish Embryos. Aquat. Toxicol. 2007, 84(4), 431-438.
13. Bar-Ilan, O.; Louis, K. M.; Yang, S. P.; Pedersen, J. A.; Hamers, R. J.; Peterson, R. E.; Heideman, W. Titanium Dioxide Nanoparticles Produce Phototoxicity in the Developing Zebrafish. Nanotoxicology 2011 Aug 10. [Epub ahead of print]
14. Henn, K.; Braunbeck, T. Dechorionation as a Tool to Improve the Fish Embryo Toxicity Test (FET) with the Zebrafish (Danio rerio). Comp. Biochem. Physiol. C Toxicol. Pharmacol. 2011, 153(1), 91-98.
15. Zhou, S.; Dong, Q.; Li, S.; Guo, J.; Wang, X.; Zhu, G. Developmental Toxicity of Cartap on Zebrafish Embryos. Aquat. Toxicol. 2009, 95(4), 339-346.
16. Kimmel, C. B.; Ballard, W. W.; Kimmel, S. R.; Ullmann, B.; Schilling, T. F. Stages of Embryonic Development of the Zebrafish. Dev. Dyn. 1995, 203(3), 253-310.
17. Westerfield, M. The Zebrafish Book: A Guide for the Laboratory Use of Zebrafish (Danio rerio). 5th ed. University of Oregon Press: Eugene, 2007.
18. Graf, S. F.; Hotzel, S.; Liebel, U.; Stemmer, A.; Knapp, H. F. Image-Based Fluidic Sorting System for Automated Zebrafish Egg Sorting into Multiwell Plates. J. Lab. Autom. 2011, 16(2), 105-111.