Discrimination of skin sensitizers from non-sensitizers by interleukin-1α and interleukin-6 production on cultured human keratinocytes

Journal of Applied Toxicology

Volumn 36, Issue 9, 2016, Pages 1129-1136

  Jung, Daun ^a   Che, Jeong Hwan ^b   Lim, Kyung Min ^c   Chun, Young Jin ^d   Heo, Yong ^e   Seok, Seung Hyeok ^a  

^a Seoul National University   (South Korea)

^b Seoul National University Hospital   (South Korea)

^c Ewha Womans University   (South Korea)

^d Chung Ang University   (South Korea)

^e Catholic University of Daegu   (South Korea)

Author keywords

cultured human keratinocyte; HaCaT; interleukin 1 ; interleukin 6; skin sensitizer

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; 2 MERCAPTOBENZOTHIAZOLE; 2 METHYL 4 ISOTHIAZOLIN 3 ONE; 2 PROPANOL; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 5 CHLORO 2 METHYL 4 ISOTHIAZOLIN 3 ONE; BENZOIC ACID; CHLOROBENZENE; CINNAMYL ALCOHOL; CITRAL; COBALT CHLORIDE; DODECYL SULFATE SODIUM; ETHYLENE GLYCOL DIMETHACRYLATE; EUGENOL; IMIDAZOLIDINYL UREA; INTERLEUKIN 18; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; INTERLEUKIN 8; ISOEUGENOL; LACTIC ACID; METHACRYLIC ACID METHYL ESTER; NICKEL CHLORIDE; PHENYL BENZOATE; PHENYLENEDIAMINE; SALICYLIC ACID; SALICYLIC ACID METHYL ESTER; UNCLASSIFIED DRUG; UREA; XYLENE;

ARTICLE; CELL CULTURE; CELL ISOLATION; CELL VIABILITY; CLINICAL EVALUATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DIAGNOSTIC ACCURACY; DRUG DISCRIMINATION; EXTRACELLULAR SPACE; HACAT CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; KERATINOCYTE; MTT ASSAY; PHENOTYPIC VARIATION; PRIORITY JOURNAL; SCREENING TEST; SENSITIVITY AND SPECIFICITY; SKIN SENSITIZATION;

EID: 84978803475     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.3274     Document Type: Article

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