메뉴 건너뛰기




Volumn 12, Issue 6, 2016, Pages

The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10

Author keywords

[No Author keywords available]

Indexed keywords

UBIQUITIN; TYPE VII SECRETION SYSTEM; VIRULENCE FACTOR;

EID: 84978796224     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1005696     Document Type: Article
Times cited : (65)

References (73)
  • 1
    • 84978903488 scopus 로고    scopus 로고
    • World Health Organization. Global tuberculosis report 2013. 2013.
    • (2013) , vol.2013
  • 2
    • 33947682112 scopus 로고    scopus 로고
    • The cell-wall core of Mycobacterium tuberculosis in the context of drug discovery
    • 17346193, .;:–. Available:
    • Brennan PJ, Crick DC, The cell-wall core of Mycobacterium tuberculosis in the context of drug discovery. Curr Top Med Chem. 2007;7: 475–88. Available: http://www.ncbi.nlm.nih.gov/pubmed/1734619317346193
    • (2007) Curr Top Med Chem , vol.7 , pp. 475-488
    • Brennan, P.J.1    Crick, D.C.2
  • 3
    • 0029061399 scopus 로고
    • The envelope of mycobacteria
    • 7574484, .;:–
    • Brennan PJ, Nikaido H, The envelope of mycobacteria. Annu Rev Biochem. 1995;64: 29–63. doi: 10.1146/annurev.bi.64.070195.0003337574484
    • (1995) Annu Rev Biochem , vol.64 , pp. 29-63
    • Brennan, P.J.1    Nikaido, H.2
  • 4
    • 41649116701 scopus 로고    scopus 로고
    • Disclosure of the mycobacterial outer membrane: cryo-electron tomography and vitreous sections reveal the lipid bilayer structure
    • 18316738, .;:–
    • Hoffmann C, Leis A, Niederweis M, Plitzko JM, Engelhardt H, Disclosure of the mycobacterial outer membrane: cryo-electron tomography and vitreous sections reveal the lipid bilayer structure. Proc Natl Acad Sci U S A. 2008;105: 3963–7. doi: 10.1073/pnas.070953010518316738
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 3963-3967
    • Hoffmann, C.1    Leis, A.2    Niederweis, M.3    Plitzko, J.M.4    Engelhardt, H.5
  • 5
    • 49449107199 scopus 로고    scopus 로고
    • Direct visualization of the outer membrane of mycobacteria and corynebacteria in their native state
    • 18567661, .;:–
    • Zuber B, Chami M, Houssin C, Dubochet J, Griffiths G, Daffé M, Direct visualization of the outer membrane of mycobacteria and corynebacteria in their native state. J Bacteriol. 2008;190: 5672–80. doi: 10.1128/JB.01919-0718567661
    • (2008) J Bacteriol , vol.190 , pp. 5672-5680
    • Zuber, B.1    Chami, M.2    Houssin, C.3    Dubochet, J.4    Griffiths, G.5    Daffé, M.6
  • 6
    • 77950418216 scopus 로고    scopus 로고
    • Direct visualization by cryo-EM of the mycobacterial capsular layer: a labile structure containing ESX-1-secreted proteins
    • 20221442
    • Sani M, Houben ENG, Geurtsen J, Pierson J, de Punder K, van Zon M, et al. Direct visualization by cryo-EM of the mycobacterial capsular layer: a labile structure containing ESX-1-secreted proteins. PLoS Pathog. 2010;6: e1000794. doi: 10.1371/journal.ppat.100079420221442
    • (2010) PLoS Pathog , vol.6 , pp. e1000794
    • Sani, M.1    Houben, E.N.G.2    Geurtsen, J.3    Pierson, J.4    de Punder, K.5    van Zon, M.6
  • 7
    • 0037741082 scopus 로고    scopus 로고
    • The capsule of Mycobacterium tuberculosis and its implications for pathogenicity
    • 10656114, .;:–
    • Daffé M, Etienne G, The capsule of Mycobacterium tuberculosis and its implications for pathogenicity. Tuber Lung Dis. 1999;79: 153–69. doi: 10.1054/tuld.1998.020010656114
    • (1999) Tuber Lung Dis , vol.79 , pp. 153-169
    • Daffé, M.1    Etienne, G.2
  • 8
    • 0028097922 scopus 로고
    • Structural features of the exocellular polysaccharides of Mycobacterium tuberculosis
    • 8297342,:–. Available:
    • Lemassu A, Daffé M, Structural features of the exocellular polysaccharides of Mycobacterium tuberculosis. Biochem J. 1994;297 Pt 2: 351–7. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1137836&tool=pmcentrez&rendertype=abstract8297342
    • (1994) Biochem J , vol.297 , pp. 351-357
    • Lemassu, A.1    Daffé, M.2
  • 9
    • 85028480038 scopus 로고    scopus 로고
    • The presence of a mycobacterial capsule is associated with differences in the protective efficacy of BCG vaccination against Mycobacterium tuberculosis in mice
    • ..;–
    • Prados-Rosales R, Carreno LJ, Weinrick B, Batista-Gonzalez A, Xu J, Chan J, et al. The presence of a mycobacterial capsule is associated with differences in the protective efficacy of BCG vaccination against Mycobacterium tuberculosis in mice. J Infect Dis. 2016; jiw153–.
    • (2016) J Infect Dis , pp. jiw153
    • Prados-Rosales, R.1    Carreno, L.J.2    Weinrick, B.3    Batista-Gonzalez, A.4    Xu, J.5    Chan, J.6
  • 10
    • 53849108791 scopus 로고    scopus 로고
    • Capsular glucan and intracellular glycogen of Mycobacterium tuberculosis: biosynthesis and impact on the persistence in mice
    • 18808383, ..;:–
    • Sambou T, Dinadayala P, Stadthagen G, Barilone N, Bordat Y, Constant P, et al. Capsular glucan and intracellular glycogen of Mycobacterium tuberculosis: biosynthesis and impact on the persistence in mice. Mol Microbiol. 2008;70: 762–74. doi: 10.1111/j.1365-2958.2008.06445.x18808383
    • (2008) Mol Microbiol , vol.70 , pp. 762-774
    • Sambou, T.1    Dinadayala, P.2    Stadthagen, G.3    Barilone, N.4    Bordat, Y.5    Constant, P.6
  • 11
    • 40749085698 scopus 로고    scopus 로고
    • The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium-host interaction
    • 18070119, ..;:–
    • Appelmelk BJ, den Dunnen J, Driessen NN, Ummels R, Pak M, Nigou J, et al. The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium-host interaction. Cell Microbiol. 2008;10: 930–44. doi: 10.1111/j.1462-5822.2007.01097.x18070119
    • (2008) Cell Microbiol , vol.10 , pp. 930-944
    • Appelmelk, B.J.1    den Dunnen, J.2    Driessen, N.N.3    Ummels, R.4    Pak, M.5    Nigou, J.6
  • 12
    • 73649100289 scopus 로고    scopus 로고
    • Systematic genetic nomenclature for type VII secretion systems
    • 19876390
    • Bitter W, Houben ENG, Bottai D, Brodin P, Brown EJ, Cox JS, et al. Systematic genetic nomenclature for type VII secretion systems. PLoS Pathog. 2009;5: e1000507. doi: 10.1371/journal.ppat.100050719876390
    • (2009) PLoS Pathog , vol.5 , pp. e1000507
    • Bitter, W.1    Houben, E.N.G.2    Bottai, D.3    Brodin, P.4    Brown, E.J.5    Cox, J.S.6
  • 13
    • 84863993689 scopus 로고    scopus 로고
    • ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria
    • 22524898, ..;:–
    • Houben D, Demangel C, van Ingen J, Perez J, Baldeón L, Abdallah AM, et al. ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria. Cell Microbiol. 2012;14: 1287–98. doi: 10.1111/j.1462-5822.2012.01799.x22524898
    • (2012) Cell Microbiol , vol.14 , pp. 1287-1298
    • Houben, D.1    Demangel, C.2    van Ingen, J.3    Perez, J.4    Baldeón, L.5    Abdallah, A.M.6
  • 14
    • 34250716965 scopus 로고    scopus 로고
    • M. tuberculosis and M. leprae translocate from the phagolysosome to the cytosol in myeloid cells
    • 17604718, ..;:–
    • van der Wel N, Hava D, Houben D, Fluitsma D, van Zon M, Pierson J, et al. M. tuberculosis and M. leprae translocate from the phagolysosome to the cytosol in myeloid cells. Cell. 2007;129: 1287–98. doi: 10.1016/j.cell.2007.05.05917604718
    • (2007) Cell , vol.129 , pp. 1287-1298
    • van der Wel, N.1    Hava, D.2    Houben, D.3    Fluitsma, D.4    van Zon, M.5    Pierson, J.6
  • 16
    • 77954668186 scopus 로고    scopus 로고
    • EspA acts as a critical mediator of ESX1-dependent virulence in Mycobacterium tuberculosis by affecting bacterial cell wall integrity
    • 20585630
    • Garces A, Atmakuri K, Chase MR, Woodworth JS, Krastins B, Rothchild AC, et al. EspA acts as a critical mediator of ESX1-dependent virulence in Mycobacterium tuberculosis by affecting bacterial cell wall integrity. PLoS Pathog. 2010;6: e1000957. doi: 10.1371/journal.ppat.100095720585630
    • (2010) PLoS Pathog , vol.6 , pp. e1000957
    • Garces, A.1    Atmakuri, K.2    Chase, M.R.3    Woodworth, J.S.4    Krastins, B.5    Rothchild, A.C.6
  • 17
    • 57349164051 scopus 로고    scopus 로고
    • Evidence for pore formation in host cell membranes by ESX-1-secreted ESAT-6 and its role in Mycobacterium marinum escape from the vacuole
    • 18852239, ..;:–
    • Smith J, Manoranjan J, Pan M, Bohsali A, Xu J, Liu J, et al. Evidence for pore formation in host cell membranes by ESX-1-secreted ESAT-6 and its role in Mycobacterium marinum escape from the vacuole. Infect Immun. 2008;76: 5478–87. doi: 10.1128/IAI.00614-0818852239
    • (2008) Infect Immun , vol.76 , pp. 5478-5487
    • Smith, J.1    Manoranjan, J.2    Pan, M.3    Bohsali, A.4    Xu, J.5    Liu, J.6
  • 18
    • 34547766513 scopus 로고    scopus 로고
    • ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity
    • 17557817, ..;:–
    • de Jonge MI, Pehau-Arnaudet G, Fretz MM, Romain F, Bottai D, Brodin P, et al. ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity. J Bacteriol. 2007;189: 6028–34. doi: 10.1128/JB.00469-0717557817
    • (2007) J Bacteriol , vol.189 , pp. 6028-6034
    • de Jonge, M.I.1    Pehau-Arnaudet, G.2    Fretz, M.M.3    Romain, F.4    Bottai, D.5    Brodin, P.6
  • 20
    • 80555149812 scopus 로고    scopus 로고
    • Mycobacterial secretion systems ESX-1 and ESX-5 play distinct roles in host cell death and inflammasome activation
    • 21957139, ..;:–
    • Abdallah AM, Bestebroer J, Savage NDL, de Punder K, van Zon M, Wilson L, et al. Mycobacterial secretion systems ESX-1 and ESX-5 play distinct roles in host cell death and inflammasome activation. J Immunol. 2011;187: 4744–53. doi: 10.4049/jimmunol.110145721957139
    • (2011) J Immunol , vol.187 , pp. 4744-4753
    • Abdallah, A.M.1    Bestebroer, J.2    Savage, N.D.L.3    de Punder, K.4    van Zon, M.5    Wilson, L.6
  • 21
    • 84930268104 scopus 로고    scopus 로고
    • The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy
    • Watson RO, Bell SL, MacDuff DA, Kimmey JM, Diner EJ, Olivas J, et al. The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy. Cell Host Microbe. 2015; doi: 10.1016/j.chom.2015.05.004
    • (2015) Cell Host Microbe
    • Watson, R.O.1    Bell, S.L.2    MacDuff, D.A.3    Kimmey, J.M.4    Diner, E.J.5    Olivas, J.6
  • 22
    • 84930254935 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1
    • Wassermann R, Gulen MF, Sala C, Perin SG, Lou Y, Rybniker J, et al. Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1. Cell Host Microbe. 2015; doi: 10.1016/j.chom.2015.05.003
    • (2015) Cell Host Microbe
    • Wassermann, R.1    Gulen, M.F.2    Sala, C.3    Perin, S.G.4    Lou, Y.5    Rybniker, J.6
  • 23
    • 84930260866 scopus 로고    scopus 로고
    • Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis
    • Collins AC, Cai H, Li T, Franco LH, Li X-D, Nair VR, et al. Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis. Cell Host Microbe. 2015; doi: 10.1016/j.chom.2015.05.005
    • (2015) Cell Host Microbe
    • Collins, A.C.1    Cai, H.2    Li, T.3    Franco, L.H.4    Li, X.-D.5    Nair, V.R.6
  • 24
    • 67651233950 scopus 로고    scopus 로고
    • PPE and PE_PGRS proteins of Mycobacterium marinum are transported via the type VII secretion system ESX-5
    • 19602152, ..;:–
    • Abdallah AM, Verboom T, Weerdenburg EM, Gey van Pittius NC, Mahasha PW, Jiménez C, et al. PPE and PE_PGRS proteins of Mycobacterium marinum are transported via the type VII secretion system ESX-5. Mol Microbiol. 2009;73: 329–40. doi: 10.1111/j.1365-2958.2009.06783.x19602152
    • (2009) Mol Microbiol , vol.73 , pp. 329-340
    • Abdallah, A.M.1    Verboom, T.2    Weerdenburg, E.M.3    Gey van Pittius, N.C.4    Mahasha, P.W.5    Jiménez, C.6
  • 25
    • 84930812557 scopus 로고    scopus 로고
    • Essential Role of the ESX-5 Secretion System in Outer Membrane Permeability of Pathogenic Mycobacteria
    • 25938982
    • Ates LS, Ummels R, Commandeur S, van der Weerd R, Sparrius M, Weerdenburg E, Viollier PH, et al. Essential Role of the ESX-5 Secretion System in Outer Membrane Permeability of Pathogenic Mycobacteria. PLOS Genet. 2015;11: e1005190. doi: 10.1371/journal.pgen.100519025938982
    • (2015) PLOS Genet , vol.11 , pp. e1005190
    • Ates, L.S.1    Ummels, R.2    Commandeur, S.3    van der Weerd, R.4    Sparrius, M.5    Weerdenburg, E.6    Viollier, P.H.7
  • 26
    • 33751323180 scopus 로고    scopus 로고
    • Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions
    • 17105670
    • Gey van Pittius NC, Sampson SL, Lee H, Kim Y, van Helden PD, Warren RM, Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions. BMC Evol Biol. 2006;6: 95. doi: 10.1186/1471-2148-6-9517105670
    • (2006) BMC Evol Biol , vol.6 , pp. 95
    • Gey van Pittius, N.C.1    Sampson, S.L.2    Lee, H.3    Kim, Y.4    van Helden, P.D.5    Warren, R.M.6
  • 27
    • 84916606186 scopus 로고    scopus 로고
    • Structure of the Mycobacterium tuberculosis type VII secretion system chaperone EspG5 in complex with PE25-PPE41 dimer
    • Korotkova N, Freire D, Phan TH, Ummels R, Creekmore CC, Evans TJ, et al. Structure of the Mycobacterium tuberculosis type VII secretion system chaperone EspG5 in complex with PE25-PPE41 dimer. Mol Microbiol. 2014; doi: 10.1111/mmi.12770
    • (2014) Mol Microbiol
    • Korotkova, N.1    Freire, D.2    Phan, T.H.3    Ummels, R.4    Creekmore, C.C.5    Evans, T.J.6
  • 28
    • 33744459472 scopus 로고    scopus 로고
    • Toward the structural genomics of complexes: crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis
    • 16690741, .;:–
    • Strong M, Sawaya MR, Wang S, Phillips M, Cascio D, Eisenberg D, Toward the structural genomics of complexes: crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2006;103: 8060–5. doi: 10.1073/pnas.060260610316690741
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 8060-8065
    • Strong, M.1    Sawaya, M.R.2    Wang, S.3    Phillips, M.4    Cascio, D.5    Eisenberg, D.6
  • 29
    • 33645236362 scopus 로고    scopus 로고
    • A novel lipase belonging to the hormone-sensitive lipase family induced under starvation to utilize stored triacylglycerol in Mycobacterium tuberculosis
    • 16354661, .;:–
    • Deb C, Daniel J, Sirakova TD, Abomoelak B, Dubey VS, Kolattukudy PE, A novel lipase belonging to the hormone-sensitive lipase family induced under starvation to utilize stored triacylglycerol in Mycobacterium tuberculosis. J Biol Chem. 2006;281: 3866–75. doi: 10.1074/jbc.M50555620016354661
    • (2006) J Biol Chem , vol.281 , pp. 3866-3875
    • Deb, C.1    Daniel, J.2    Sirakova, T.D.3    Abomoelak, B.4    Dubey, V.S.5    Kolattukudy, P.E.6
  • 30
    • 79956306859 scopus 로고    scopus 로고
    • Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) protein domains target LipY lipases of pathogenic mycobacteria to the cell surface via the ESX-5 pathway
    • 21471225, ..;:–
    • Daleke MH, Cascioferro A, de Punder K, Ummels R, Abdallah AM, van der Wel N, et al. Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) protein domains target LipY lipases of pathogenic mycobacteria to the cell surface via the ESX-5 pathway. J Biol Chem. 2011;286: 19024–34. doi: 10.1074/jbc.M110.20496621471225
    • (2011) J Biol Chem , vol.286 , pp. 19024-19034
    • Daleke, M.H.1    Cascioferro, A.2    de Punder, K.3    Ummels, R.4    Abdallah, A.M.5    van der Wel, N.6
  • 31
    • 2442515282 scopus 로고    scopus 로고
    • Rv1818c-encoded PE_PGRS protein of Mycobacterium tuberculosis is surface exposed and influences bacterial cell structure
    • 15101979, .;:–
    • Delogu G, Pusceddu C, Bua A, Fadda G, Brennan MJ, Zanetti S, Rv1818c-encoded PE_PGRS protein of Mycobacterium tuberculosis is surface exposed and influences bacterial cell structure. Mol Microbiol. 2004;52: 725–33. doi: 10.1111/j.1365-2958.2004.04007.x15101979
    • (2004) Mol Microbiol , vol.52 , pp. 725-733
    • Delogu, G.1    Pusceddu, C.2    Bua, A.3    Fadda, G.4    Brennan, M.J.5    Zanetti, S.6
  • 32
    • 34548411365 scopus 로고    scopus 로고
    • A mycobacterium ESX-1-secreted virulence factor with unique requirements for export
    • 17676952
    • McLaughlin B, Chon JS, MacGurn JA, Carlsson F, Cheng TL, Cox JS, et al. A mycobacterium ESX-1-secreted virulence factor with unique requirements for export. PLoS Pathog. 2007;3: e105. doi: 10.1371/journal.ppat.003010517676952
    • (2007) PLoS Pathog , vol.3 , pp. e105
    • McLaughlin, B.1    Chon, J.S.2    MacGurn, J.A.3    Carlsson, F.4    Cheng, T.L.5    Cox, J.S.6
  • 33
    • 70349414430 scopus 로고    scopus 로고
    • Role of phosphatidylinositol mannosides in the interaction between mycobacteria and DC-SIGN
    • 19651855, ..;:–
    • Driessen NN, Ummels R, Maaskant JJ, Gurcha SS, Besra GS, Ainge GD, et al. Role of phosphatidylinositol mannosides in the interaction between mycobacteria and DC-SIGN. Infect Immun. 2009;77: 4538–47. doi: 10.1128/IAI.01256-0819651855
    • (2009) Infect Immun , vol.77 , pp. 4538-4547
    • Driessen, N.N.1    Ummels, R.2    Maaskant, J.J.3    Gurcha, S.S.4    Besra, G.S.5    Ainge, G.D.6
  • 34
    • 0021715224 scopus 로고
    • Production and characterization of monoclonal antibodies to Mycobacterium tuberculosis, M. bovis (BCG) and M. leprae
    • ..;:–. Available:
    • Kolk AH, Ho ML, Klatser PR, Eggelte TA, Kuijper S, de Jonge S, et al. Production and characterization of monoclonal antibodies to Mycobacterium tuberculosis, M. bovis (BCG) and M. leprae. Clin Exp Immunol. 1984;58: 511–21. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1577099&tool=pmcentrez&rendertype=abstract
    • (1984) Clin Exp Immunol , vol.58 , pp. 511-521
    • Kolk, A.H.1    Ho, M.L.2    Klatser, P.R.3    Eggelte, T.A.4    Kuijper, S.5    de Jonge, S.6
  • 36
    • 33749997722 scopus 로고    scopus 로고
    • A specific secretion system mediates PPE41 transport in pathogenic mycobacteria
    • 17076665, ..;:–
    • Abdallah AM, Verboom T, Hannes F, Safi M, Strong M, Eisenberg D, et al. A specific secretion system mediates PPE41 transport in pathogenic mycobacteria. Mol Microbiol. 2006;62: 667–79. doi: 10.1111/j.1365-2958.2006.05409.x17076665
    • (2006) Mol Microbiol , vol.62 , pp. 667-679
    • Abdallah, A.M.1    Verboom, T.2    Hannes, F.3    Safi, M.4    Strong, M.5    Eisenberg, D.6
  • 37
    • 84898864480 scopus 로고    scopus 로고
    • A novel ESX-1 locus reveals that surface-associated ESX-1 substrates mediate virulence in Mycobacterium marinum
    • 24610712, .;:–
    • Kennedy GM, Hooley GC, Champion MM, Mba Medie F, Champion PAD, A novel ESX-1 locus reveals that surface-associated ESX-1 substrates mediate virulence in Mycobacterium marinum. J Bacteriol. 2014;196: 1877–88. doi: 10.1128/JB.01502-1424610712
    • (2014) J Bacteriol , vol.196 , pp. 1877-1888
    • Kennedy, G.M.1    Hooley, G.C.2    Champion, M.M.3    Mba Medie, F.4    Champion, P.A.D.5
  • 38
    • 4644320227 scopus 로고    scopus 로고
    • A mycobacterial virulence gene cluster extending RD1 is required for cytolysis, bacterial spreading and ESAT-6 secretion
    • 15341647, .;:–
    • Gao L-Y, Guo S, McLaughlin B, Morisaki H, Engel JN, Brown EJ, A mycobacterial virulence gene cluster extending RD1 is required for cytolysis, bacterial spreading and ESAT-6 secretion. Mol Microbiol. 2004;53: 1677–93. doi: 10.1111/j.1365-2958.2004.04261.x15341647
    • (2004) Mol Microbiol , vol.53 , pp. 1677-1693
    • Gao, L.-Y.1    Guo, S.2    McLaughlin, B.3    Morisaki, H.4    Engel, J.N.5    Brown, E.J.6
  • 39
    • 36348929363 scopus 로고    scopus 로고
    • Identification and real-time imaging of a myc-expressing neutrophil population involved in inflammation and mycobacterial granuloma formation in zebrafish
    • 17553562, ..;:–
    • Meijer AH, van der Sar AM, Cunha C, Lamers GEM, Laplante MA, Kikuta H, et al. Identification and real-time imaging of a myc-expressing neutrophil population involved in inflammation and mycobacterial granuloma formation in zebrafish. Dev Comp Immunol. 2008;32: 36–49. doi: 10.1016/j.dci.2007.04.00317553562
    • (2008) Dev Comp Immunol , vol.32 , pp. 36-49
    • Meijer, A.H.1    van der Sar, A.M.2    Cunha, C.3    Lamers, G.E.M.4    Laplante, M.A.5    Kikuta, H.6
  • 40
    • 84865220380 scopus 로고    scopus 로고
    • Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway
    • 22901810, .;:–
    • Watson RO, Manzanillo PS, Cox JS, Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway. Cell. 2012;150: 803–15. doi: 10.1016/j.cell.2012.06.04022901810
    • (2012) Cell , vol.150 , pp. 803-815
    • Watson, R.O.1    Manzanillo, P.S.2    Cox, J.S.3
  • 41
    • 79955961624 scopus 로고    scopus 로고
    • Mycobacterium marinum induces a marked LC3 recruitment to its containing phagosome that depends on a functional ESX-1 secretion system
    • 21447143, .;:–
    • Lerena MC, Colombo MI, Mycobacterium marinum induces a marked LC3 recruitment to its containing phagosome that depends on a functional ESX-1 secretion system. Cell Microbiol. 2011;13: 814–35. doi: 10.1111/j.1462-5822.2011.01581.x21447143
    • (2011) Cell Microbiol , vol.13 , pp. 814-835
    • Lerena, M.C.1    Colombo, M.I.2
  • 42
    • 84859919593 scopus 로고    scopus 로고
    • ESX-5-deficient Mycobacterium marinum is hypervirulent in adult zebrafish
    • 22256857, ..;:–
    • Weerdenburg EM, Abdallah AM, Mitra S, de Punder K, van der Wel NN, Bird S, et al. ESX-5-deficient Mycobacterium marinum is hypervirulent in adult zebrafish. Cell Microbiol. 2012;14: 728–39. doi: 10.1111/j.1462-5822.2012.01755.x22256857
    • (2012) Cell Microbiol , vol.14 , pp. 728-739
    • Weerdenburg, E.M.1    Abdallah, A.M.2    Mitra, S.3    de Punder, K.4    van der Wel, N.N.5    Bird, S.6
  • 43
    • 79959658128 scopus 로고    scopus 로고
    • Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component
    • 21372049, ..;:–
    • Stoop EJM, Schipper T, Huber SKR, Nezhinsky AE, Verbeek FJ, Gurcha SS, et al. Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component. Dis Model Mech. 2011;4: 526–36. doi: 10.1242/dmm.00667621372049
    • (2011) Dis Model Mech , vol.4 , pp. 526-536
    • Stoop, E.J.M.1    Schipper, T.2    Huber, S.K.R.3    Nezhinsky, A.E.4    Verbeek, F.J.5    Gurcha, S.S.6
  • 44
    • 0003170333 scopus 로고
    • An electron microscope study of the disposition and fine structure of Mycobacterium lepraemurium in mouse spleen
    • 13630872, .;:–. Available:
    • CHAPMAN GB, HANKS JH, WALLACE JH, An electron microscope study of the disposition and fine structure of Mycobacterium lepraemurium in mouse spleen. J Bacteriol. 1959;77: 205–11. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=290351&tool=pmcentrez&rendertype=abstract13630872
    • (1959) J Bacteriol , vol.77 , pp. 205-211
    • Chapman, G.B.1    Hanks, J.H.2    Wallace, J.H.3
  • 45
    • 0030070034 scopus 로고    scopus 로고
    • Identification of the surface-exposed lipids on the cell envelopes of Mycobacterium tuberculosis and other mycobacterial species
    • 8550466, ..;:–. Available:
    • Ortalo-Magné A, Lemassu A, Lanéelle MA, Bardou F, Silve G, Gounon P, et al. Identification of the surface-exposed lipids on the cell envelopes of Mycobacterium tuberculosis and other mycobacterial species. J Bacteriol. 1996;178: 456–61. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=177678&tool=pmcentrez&rendertype=abstract8550466
    • (1996) J Bacteriol , vol.178 , pp. 456-461
    • Ortalo-Magné, A.1    Lemassu, A.2    Lanéelle, M.A.3    Bardou, F.4    Silve, G.5    Gounon, P.6
  • 46
  • 47
    • 84871289607 scopus 로고    scopus 로고
    • The ESX-5 associated eccB-EccC locus is essential for Mycobacterium tuberculosis viability
    • 23284869
    • Di Luca M, Bottai D, Batoni G, Orgeur M, Aulicino A, Counoupas C, et al. The ESX-5 associated eccB-EccC locus is essential for Mycobacterium tuberculosis viability. PLoS One. 2012;7: e52059. doi: 10.1371/journal.pone.005205923284869
    • (2012) PLoS One , vol.7 , pp. e52059
    • Di Luca, M.1    Bottai, D.2    Batoni, G.3    Orgeur, M.4    Aulicino, A.5    Counoupas, C.6
  • 48
    • 84924363115 scopus 로고    scopus 로고
    • Cytosolic Access of Mycobacterium tuberculosis: Critical Impact of Phagosomal Acidification Control and Demonstration of Occurrence In Vivo
    • 25658322
    • Simeone R, Sayes F, Song O, Gröschel MI, Brodin P, Brosch R, et al. Cytosolic Access of Mycobacterium tuberculosis: Critical Impact of Phagosomal Acidification Control and Demonstration of Occurrence In Vivo. PLoS Pathog. 2015;11: e1004650. doi: 10.1371/journal.ppat.100465025658322
    • (2015) PLoS Pathog , vol.11 , pp. e1004650
    • Simeone, R.1    Sayes, F.2    Song, O.3    Gröschel, M.I.4    Brodin, P.5    Brosch, R.6
  • 49
    • 84871752747 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis ESAT-6 exhibits a unique membrane-interacting activity that is not found in its ortholog from non-pathogenic Mycobacterium smegmatis
    • 23150662, .;:–
    • De Leon J, Jiang G, Ma Y, Rubin E, Fortune S, Sun J, Mycobacterium tuberculosis ESAT-6 exhibits a unique membrane-interacting activity that is not found in its ortholog from non-pathogenic Mycobacterium smegmatis. J Biol Chem. 2012;287: 44184–91. doi: 10.1074/jbc.M112.42086923150662
    • (2012) J Biol Chem , vol.287 , pp. 44184-44191
    • De Leon, J.1    Jiang, G.2    Ma, Y.3    Rubin, E.4    Fortune, S.5    Sun, J.6
  • 50
    • 84924942008 scopus 로고    scopus 로고
    • Characterization of Mycobacterium tuberculosis EsxA membrane insertion: roles of N- and C-terminal flexible arms and central helix-turn-helix motif
    • 25645924, .;:–
    • Ma Y, Keil V, Sun J, Characterization of Mycobacterium tuberculosis EsxA membrane insertion: roles of N- and C-terminal flexible arms and central helix-turn-helix motif. J Biol Chem. 2015;290: 7314–22. doi: 10.1074/jbc.M114.62207625645924
    • (2015) J Biol Chem , vol.290 , pp. 7314-7322
    • Ma, Y.1    Keil, V.2    Sun, J.3
  • 51
    • 77949556108 scopus 로고    scopus 로고
    • Identification of mycobacterial alpha-glucan as a novel ligand for DC-SIGN: involvement of mycobacterial capsular polysaccharides in host immune modulation
    • ..;:–
    • Geurtsen J, Chedammi S, Mesters J, Cot M, Driessen NN, Sambou T, et al. Identification of mycobacterial alpha-glucan as a novel ligand for DC-SIGN: involvement of mycobacterial capsular polysaccharides in host immune modulation. J Immunol. 2009;183: 5221–31.
    • (2009) J Immunol , vol.183 , pp. 5221-5231
    • Geurtsen, J.1    Chedammi, S.2    Mesters, J.3    Cot, M.4    Driessen, N.N.5    Sambou, T.6
  • 53
    • 33748655254 scopus 로고    scopus 로고
    • Mycobacterial mutants with defective control of phagosomal acidification
    • 16322769, .;:–
    • Stewart GR, Patel J, Robertson BD, Rae A, Young DB, Mycobacterial mutants with defective control of phagosomal acidification. PLoS Pathog. 2005;1: 269–78. doi: 10.1371/journal.ppat.001003316322769
    • (2005) PLoS Pathog , vol.1 , pp. 269-278
    • Stewart, G.R.1    Patel, J.2    Robertson, B.D.3    Rae, A.4    Young, D.B.5
  • 54
    • 84905216311 scopus 로고    scopus 로고
    • The molecular biology of mycobacterial trehalose in the quest for advanced tuberculosis therapies
    • 24858083, .;:–
    • Nobre A, Alarico S, Maranha A, Mendes V, Empadinhas N, The molecular biology of mycobacterial trehalose in the quest for advanced tuberculosis therapies. Microbiology. 2014;160: 1547–70. doi: 10.1099/mic.0.075895-024858083
    • (2014) Microbiology , vol.160 , pp. 1547-1570
    • Nobre, A.1    Alarico, S.2    Maranha, A.3    Mendes, V.4    Empadinhas, N.5
  • 55
    • 84862017657 scopus 로고    scopus 로고
    • Unexpected link between lipooligosaccharide biosynthesis and surface protein release in Mycobacterium marinum
    • 22505711, ..;:–
    • van der Woude AD, Sarkar D, Bhatt A, Sparrius M, Raadsen S a, Boon L, et al. Unexpected link between lipooligosaccharide biosynthesis and surface protein release in Mycobacterium marinum. J Biol Chem. 2012;287: 20417–29. doi: 10.1074/jbc.M111.33646122505711
    • (2012) J Biol Chem , vol.287 , pp. 20417-20429
    • van der Woude, A.D.1    Sarkar, D.2    Bhatt, A.3    Sparrius, M.4    Raadsen, S.5    Boon, L.6
  • 56
    • 78649738763 scopus 로고    scopus 로고
    • Portrait of a pathogen: the Mycobacterium tuberculosis proteome in vivo
    • 21085642
    • Kruh NA, Troudt J, Izzo A, Prenni J, Dobos KM, Portrait of a pathogen: the Mycobacterium tuberculosis proteome in vivo. PLoS One. 2010;5: e13938. doi: 10.1371/journal.pone.001393821085642
    • (2010) PLoS One , vol.5 , pp. e13938
    • Kruh, N.A.1    Troudt, J.2    Izzo, A.3    Prenni, J.4    Dobos, K.M.5
  • 57
    • 80755135531 scopus 로고    scopus 로고
    • PPE_MPTR genes are differentially expressed by Mycobacterium tuberculosis in vivo
    • ..;:–
    • Soldini S, Palucci I, Zumbo A, Sali M, Ria F, Manganelli R, et al. PPE_MPTR genes are differentially expressed by Mycobacterium tuberculosis in vivo. Tuberculosis (Edinb). 2011;91: 563–8. doi: 10.1016/j.tube.2011.08.002
    • (2011) Tuberculosis (Edinb) , vol.91 , pp. 563-568
    • Soldini, S.1    Palucci, I.2    Zumbo, A.3    Sali, M.4    Ria, F.5    Manganelli, R.6
  • 59
    • 0026690549 scopus 로고
    • Characterization of a major polymorphic tandem repeat in Mycobacterium tuberculosis and its potential use in the epidemiology of Mycobacterium kansasii and Mycobacterium gordonae
    • 1350781, .;:–. Available:
    • Hermans PW, van Soolingen D, van Embden JD, Characterization of a major polymorphic tandem repeat in Mycobacterium tuberculosis and its potential use in the epidemiology of Mycobacterium kansasii and Mycobacterium gordonae. J Bacteriol. 1992;174: 4157–65. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=206128&tool=pmcentrez&rendertype=abstract1350781
    • (1992) J Bacteriol , vol.174 , pp. 4157-4165
    • Hermans, P.W.1    van Soolingen, D.2    van Embden, J.D.3
  • 60
    • 0032508046 scopus 로고    scopus 로고
    • Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
    • 9634230, ..;:–
    • Cole ST, Brosch R, Parkhill J, Garnier T, Churcher C, Harris D, et al. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature. 1998;393: 537–44. doi: 10.1038/311599634230
    • (1998) Nature , vol.393 , pp. 537-544
    • Cole, S.T.1    Brosch, R.2    Parkhill, J.3    Garnier, T.4    Churcher, C.5    Harris, D.6
  • 61
    • 7044286148 scopus 로고    scopus 로고
    • Mycobacterium marinum strains can be divided into two distinct types based on genetic diversity and virulence
    • 15501758, .;:–
    • van der Sar AM, Abdallah AM, Sparrius M, Reinders E, Vandenbroucke-Grauls CMJE, Bitter W, Mycobacterium marinum strains can be divided into two distinct types based on genetic diversity and virulence. Infect Immun. 2004;72: 6306–12. doi: 10.1128/IAI.72.11.6306-6312.200415501758
    • (2004) Infect Immun , vol.72 , pp. 6306-6312
    • van der Sar, A.M.1    Abdallah, A.M.2    Sparrius, M.3    Reinders, E.4    Vandenbroucke-Grauls, C.M.J.E.5    Bitter, W.6
  • 62
    • 84928185853 scopus 로고    scopus 로고
    • Genome-wide transposon mutagenesis indicates that Mycobacterium marinum customizes its virulence mechanisms for survival and replication in different hosts
    • ..; IAI.03050–14
    • Weerdenburg EM, Abdallah AM, Rangkuti F, Abd El Ghany M, Otto TD, Adroub SA, et al. Genome-wide transposon mutagenesis indicates that Mycobacterium marinum customizes its virulence mechanisms for survival and replication in different hosts. Infect Immun. 2015; IAI.03050–14. doi: 10.1128/IAI.03050-14
    • (2015) Infect Immun
    • Weerdenburg, E.M.1    Abdallah, A.M.2    Rangkuti, F.3    Abd El Ghany, M.4    Otto, T.D.5    Adroub, S.A.6
  • 63
    • 0038472048 scopus 로고    scopus 로고
    • A postgenomic method for predicting essential genes at subsaturation levels of mutagenesis: application to Mycobacterium tuberculosis
    • 12775759, ..;:–
    • Lamichhane G, Zignol M, Blades NJ, Geiman DE, Dougherty A, Grosset J, et al. A postgenomic method for predicting essential genes at subsaturation levels of mutagenesis: application to Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2003;100: 7213–8. doi: 10.1073/pnas.123143210012775759
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 7213-7218
    • Lamichhane, G.1    Zignol, M.2    Blades, N.J.3    Geiman, D.E.4    Dougherty, A.5    Grosset, J.6
  • 64
    • 0345701347 scopus 로고    scopus 로고
    • Genes required for mycobacterial growth defined by high density mutagenesis
    • 12657046, .;:–. Available:
    • Sassetti CM, Boyd DH, Rubin EJ, Genes required for mycobacterial growth defined by high density mutagenesis. Mol Microbiol. 2003;48: 77–84. Available: http://www.ncbi.nlm.nih.gov/pubmed/1265704612657046
    • (2003) Mol Microbiol , vol.48 , pp. 77-84
    • Sassetti, C.M.1    Boyd, D.H.2    Rubin, E.J.3
  • 65
    • 0031934736 scopus 로고    scopus 로고
    • A reliable amplification technique for the characterization of genomic DNA sequences flanking insertion sequences
    • 9453159, .;:–. Available:
    • Prod’hom G, Lagier B, Pelicic V, Hance AJ, Gicquel B, Guilhot C, A reliable amplification technique for the characterization of genomic DNA sequences flanking insertion sequences. FEMS Microbiol Lett. 1998;158: 75–81. Available: http://www.ncbi.nlm.nih.gov/pubmed/94531599453159
    • (1998) FEMS Microbiol Lett , vol.158 , pp. 75-81
    • Prod’hom, G.1    Lagier, B.2    Pelicic, V.3    Hance, A.J.4    Gicquel, B.5    Guilhot, C.6
  • 66
    • 0031931453 scopus 로고    scopus 로고
    • B-cell epitopes and quantification of the ESAT-6 protein of Mycobacterium tuberculosis
    • 9453632, ..;:–. Available:
    • Harboe M, Malin AS, Dockrell HS, Wiker HG, Ulvund G, Holm A, et al. B-cell epitopes and quantification of the ESAT-6 protein of Mycobacterium tuberculosis. Infect Immun. 1998;66: 717–23. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=107962&tool=pmcentrez&rendertype=abstract9453632
    • (1998) Infect Immun , vol.66 , pp. 717-723
    • Harboe, M.1    Malin, A.S.2    Dockrell, H.S.3    Wiker, H.G.4    Ulvund, G.5    Holm, A.6
  • 67
    • 59249088584 scopus 로고    scopus 로고
    • Polar localization of virulence-related Esx-1 secretion in mycobacteria
    • 19180234
    • Carlsson F, Joshi S a, Rangell L, Brown EJ, Polar localization of virulence-related Esx-1 secretion in mycobacteria. PLoS Pathog. 2009;5: e1000285. doi: 10.1371/journal.ppat.100028519180234
    • (2009) PLoS Pathog , vol.5 , pp. e1000285
    • Carlsson, F.1    Joshi, S.2    Rangell, L.3    Brown, E.J.4
  • 68
    • 0019193171 scopus 로고
    • Adherence of bacteria to hydrocarbons: A simple method for measuring cell-surface hydrophobicity
    • .;;:–
    • Rosenberg M, Gutnick D, Rosenberg E, Adherence of bacteria to hydrocarbons: A simple method for measuring cell-surface hydrophobicity. FEMS Microbiol Lett. Blackwell Publishing Ltd; 1980;9: 29–33. doi: 10.1111/j.1574-6968.1980.tb05599.x
    • (1980) FEMS Microbiol Lett. Blackwell Publishing Ltd , vol.9 , pp. 29-33
    • Rosenberg, M.1    Gutnick, D.2    Rosenberg, E.3
  • 69
    • 84929692711 scopus 로고    scopus 로고
    • A new dehydratase conferring innate resistance to thiacetazone and intra-amoebal survival of Mycobacterium smegmatis
    • 25754266, ..;:–
    • Carrère-Kremer S, Blaise M, Singh VK, Alibaud L, Tuaillon E, Halloum I, et al. A new dehydratase conferring innate resistance to thiacetazone and intra-amoebal survival of Mycobacterium smegmatis. Mol Microbiol. 2015;96: 1085–102. doi: 10.1111/mmi.1299225754266
    • (2015) Mol Microbiol , vol.96 , pp. 1085-1102
    • Carrère-Kremer, S.1    Blaise, M.2    Singh, V.K.3    Alibaud, L.4    Tuaillon, E.5    Halloum, I.6
  • 71
    • 0032247240 scopus 로고    scopus 로고
    • Preparation of cell-wall fractions from mycobacteria
    • . [Internet]
    • Besra GS, Preparation of cell-wall fractions from mycobacteria. [Internet]. Methods in molecular biology (Clifton, N.J.). 1998. doi: 10.1385/0-89603-471-2:91
    • (1998) Methods in molecular biology (Clifton, N.J.)
    • Besra, G.S.1
  • 72
    • 84903777311 scopus 로고    scopus 로고
    • CNS myelin induces regulatory functions of DC-SIGN-expressing, antigen-presenting cells via cognate interaction with MOG
    • 24935259, ..;:–
    • García-Vallejo JJ, Ilarregui JM, Kalay H, Chamorro S, Koning N, Unger WW, et al. CNS myelin induces regulatory functions of DC-SIGN-expressing, antigen-presenting cells via cognate interaction with MOG. J Exp Med. 2014;211: 1465–83. doi: 10.1084/jem.2012219224935259
    • (2014) J Exp Med , vol.211 , pp. 1465-1483
    • García-Vallejo, J.J.1    Ilarregui, J.M.2    Kalay, H.3    Chamorro, S.4    Koning, N.5    Unger, W.W.6
  • 73
    • 84926655625 scopus 로고    scopus 로고
    • The Consequences of Multiple Simultaneous C-Type Lectin-Ligand Interactions: DCIR Alters the Endo-Lysosomal Routing of DC-SIGN
    • 25806031
    • García-Vallejo JJ, Bloem K, Knippels LMJ, Garssen J, van Vliet SJ, van Kooyk Y, The Consequences of Multiple Simultaneous C-Type Lectin-Ligand Interactions: DCIR Alters the Endo-Lysosomal Routing of DC-SIGN. Front Immunol. 2015;6: 87. doi: 10.3389/fimmu.2015.0008725806031
    • (2015) Front Immunol , vol.6 , pp. 87
    • García-Vallejo, J.J.1    Bloem, K.2    Knippels, L.M.J.3    Garssen, J.4    van Vliet, S.J.5    van Kooyk, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.