Identification of mycobacterial α-glucan as a novel ligand for DC-SIGN: Involvement of mycobacterial capsular polysaccharides in host immune modulation

Journal of Immunology

Volumn 183, Issue 8, 2009, Pages 5221-5231

  Geurtsen, Jeroen ^a   Chedammi, Sunita ^a   Mesters, Joram ^a   Cot, Marlène ^b   Driessen, Nicole N ^a   Sambou, Tounkang ^b   Kakutani, Ryo ^c   Ummels, Roy ^a   Maaskant, Janneke ^a   Takata, Hiroki ^c   Baba, Otto ^d   Terashima, Tatsuo ^d   Bovin, Nicolai ^e   Vandenbroucke Grauls, Christina M J E ^a   Nigou, Jérôme ^b   Puzo, Germain ^b   Lemassu, Anne ^b   Daffé, Mamadou ^b   Appelmelk, Ben J ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

^c EZAKI GLICO CO LTD   (Japan)

^d TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^e SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GLUCAN; CD209 ANTIGEN; GLUCAN; GLYCOGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; LECTIN; LIPOARABINOMANNAN; LIPOPOLYSACCHARIDE; MANNOSE; POLYSACCHARIDE; TOLL LIKE RECEPTOR 2; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; BACTERIAL CELL WALL; BACTERIAL MEMBRANE; CELL STRAIN HEK293; CONTROLLED STUDY; HOST; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOMODULATION; MACROPHAGE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; RECOGNITION;

BACTERIAL CAPSULES; CELL ADHESION MOLECULES; CELLS, CULTURED; DENDRITIC CELLS; GLUCANS; HUMANS; INTERLEUKIN-10; LECTINS, C-TYPE; LIPOPOLYSACCHARIDES; MYCOBACTERIUM TUBERCULOSIS; NF-KAPPA B; RECEPTORS, CELL SURFACE; TOLL-LIKE RECEPTOR 2;

EID: 77949556108     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0900768     Document Type: Article

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