Characterization of Mycobacterium tuberculosis EsxA membrane insertion: Roles of N- and C-terminal flexible arms and central helix-turn-helix motif

Journal of Biological Chemistry

Volumn 290, Issue 11, 2015, Pages 7314-7322

  Ma, Yue ^a   Keil, Verena ^a   Sun, Jianjun ^a  

^a UNIVERSITY OF TEXAS AT EL PASO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BACTERIA; FLEXIBLE MANIPULATORS; FLUORESCENCE; ROBOTIC ARMS;

ENVIRONMENTALLY SENSITIVE; HELIX-TURN-HELIX MOTIFS; INTRINSIC TRYPTOPHAN FLUORESCENCES; MEMBRANE DISRUPTION; MOLECULAR MECHANISM; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; ORGANIZED STRUCTURE;

MEMBRANES;

8 ANILINO 1 NAPHTHALENESULFONIC ACID; EARLY SECRETORY ANTIGENIC TARGET 6; HELIX LOOP HELIX PROTEIN; VIRULENCE FACTOR; BACTERIAL ANTIGEN; BACTERIAL PROTEIN; ESAT-6 PROTEIN, MYCOBACTERIUM TUBERCULOSIS; LIPOSOME;

ACIDIFICATION; ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHANNEL GATING; CHEMICAL LABELING; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; FLUORESCENCE ANALYSIS; FLUORESCENCE BASED LIPOSOME LEAKAGE ASSAY; HOST PATHOGEN INTERACTION; HYDROPHOBICITY; INTRINSIC TRYPTOPHAN FLUORESCENCE; LIPOSOME MEMBRANE; MEMBRANE BIOLOGY; MEMBRANE DAMAGE; MEMBRANE FORMATION; MEMBRANE INSERTION; MEMBRANE SPANNING PORE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN MOTIF; PROTEIN PURIFICATION; PROTEIN SECONDARY STRUCTURE; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS; AMINO ACID SEQUENCE; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS; PATHOGENICITY; PHYSIOLOGY; TUBERCULOSIS; X RAY CRYSTALLOGRAPHY;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS;

AMINO ACID SEQUENCE; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CELL MEMBRANE; CRYSTALLOGRAPHY, X-RAY; HELIX-TURN-HELIX MOTIFS; HOST-PATHOGEN INTERACTIONS; HUMANS; HYDROGEN-ION CONCENTRATION; LIPOSOMES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; TUBERCULOSIS; VIRULENCE FACTORS;

EID: 84924942008     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.622076     Document Type: Article

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