Mycobacterium tuberculosis ESAT-6 exhibits a unique membrane-interacting activity that is not found in its ortholog from non-pathogenic Mycobacterium smegmatis

Journal of Biological Chemistry

Volumn 287, Issue 53, 2012, Pages 44184-44191

  De Leon, Joaquin ^a   Jiang, Guozhong ^a   Ma, Yue ^a   Rubin, Eric ^b   Fortune, Sarah ^b   Sun, Jianjun ^a  

^a UNIVERSITY OF TEXAS AT EL PASO   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDIC CONDITIONS; ACIDIC PH; BIOLOGICAL FUNCTIONS; CONFORMATIONAL CHANGE; CYTOSOLIC; HETERODIMERS; LIPOSOMAL MEMBRANES; M. TUBERCULOSIS; MEMBRANE LEAKAGES; MODEL MEMBRANES; MOLECULAR MECHANISM; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; ORTHOLOGS; PH-DEPENDENT; PHAGOSOMES; TRISULFONIC ACID;

BACTERIA; BIOMOLECULES; BROMINE COMPOUNDS; LIPOSOMES; TUBES (COMPONENTS); XYLENE;

MEMBRANES;

CULTURE FILTRATE PROTEIN 10; EARLY SECRETORY ANTIGENIC TARGET 6;

ACIDIFICATION; ACIDITY; ARTICLE; BACTERIAL VIRULENCE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYTOLYSIS; HYDROPHOBICITY; MEMBRANE VESICLE; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN REFOLDING;

AMINO ACID SEQUENCE; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CELL MEMBRANE; DIMERIZATION; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM INFECTIONS; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; PROTEIN BINDING; SEQUENCE ALIGNMENT;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS;

EID: 84871752747     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.420869     Document Type: Article

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