The novel enterochromaffin marker Lmx1a regulates serotonin biosynthesis in enteroendocrine cell lineages downstream of Nkx2.2

Development (Cambridge)

Volumn 143, Issue 14, 2016, Pages 2616-2628

  Gross, Stefanie ^a   Garofalo, Diana C ^a   Balderes, Dina A ^a   Mastracci, Teresa L ^a,d   Dias, José M ^b   Perlmann, Thomas ^b,c   Ericson, Johan ^b   Sussel, Lori ^a,e  

^a Department of Medicine   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

^c LUDWIG INSTITUTE FOR CANCER RESEARCH   (Sweden)

^d INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF COLORADO DENVER   (United States)

Author keywords

Enterochromaffin; Enteroendocrine cells; Intestine; Lmx1a; Nkx2.2; Serotonin

Indexed keywords

BIOLOGICAL MARKER; CHOLECYSTOKININ; CHROMOGRANIN A; CHROMOGRANIN B; GASTRIC INHIBITORY POLYPEPTIDE; GHRELIN; NEUROPEPTIDE Y; NEUROTENSIN; PEPTIDE YY; SECRETIN; SEROTONIN; SOMATOSTATIN; TACHYKININ; TACHYKININ 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR LMX1A; TRANSCRIPTION FACTOR NKX2.2; TRYPTOPHAN HYDROXYLASE; TRYPTOPHAN HYDROXYLASE 1; UNCLASSIFIED DRUG; VASOACTIVE INTESTINAL POLYPEPTIDE; HOMEODOMAIN PROTEIN; LIM HOMEODOMAIN PROTEIN; LMX1A PROTEIN, MOUSE; MESSENGER RNA; NKX-2.2 HOMEDOMAIN PROTEIN;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CELL POPULATION; COLON; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DUODENUM; EMBRYO; EMBRYO DEVELOPMENT; ENTEROCHROMAFFIN CELL; ENTEROENDOCRINE CELL; GENE EXPRESSION; HORMONE RELEASE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEROTONIN METABOLISM; STEM CELL; AGING; ANIMAL; BIOLOGICAL MODEL; BIOSYNTHESIS; C57BL MOUSE; CHEMISTRY; CYTOLOGY; GENE DELETION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MUTATION; PROTEIN DOMAIN; SEQUENCE ANALYSIS;

AGING; ANIMALS; BIOMARKERS; CELL LINEAGE; COLON; DUODENUM; ENTEROCHROMAFFIN CELLS; ENTEROENDOCRINE CELLS; GENE DELETION; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; LIM-HOMEODOMAIN PROTEINS; MICE, INBRED C57BL; MODELS, BIOLOGICAL; MUTATION; POLYMERASE CHAIN REACTION; PROTEIN DOMAINS; RNA, MESSENGER; SEQUENCE ANALYSIS, RNA; SEROTONIN; STEM CELLS; TRANSCRIPTION FACTORS;

EID: 84978761781     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.130682     Document Type: Article

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