DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells

Nature Genetics

Volumn 48, Issue 9, 2016, Pages 1014-1023

  Zhang, Xiaotian ^a,b   Su, Jianzhong ^a   Jeong, Mira ^a,b   Ko, Myunggon ^c,d   Huang, Yun ^e   Park, Hyun Jung ^a   Guzman, Anna ^a,b   Lei, Yong ^a,b   Huang, Yung Hsin ^a,b   Rao, Anjana ^c   Li, Wei ^a   Goodell, Margaret A ^a,b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b CENTER FOR CELL AND GENE THERAPY   (United States)

^c LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^d Ulsan National Institute of Science and Technology   (South Korea)

^e UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA METHYLTRANSFERASE 3A; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA BINDING PROTEIN; ERYTHROID KRUPPEL-LIKE FACTOR; ERYTHROPOIETIN RECEPTOR; KRUPPEL LIKE FACTOR; ONCOPROTEIN; TET2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW DEPRESSION; CELL DIFFERENTIATION; CELL SELF-RENEWAL; CHRONIC MYELOMONOCYTIC LEUKEMIA; CONTROLLED STUDY; DNA METHYLATION; EPOR GENE; ERYTHROCYTE; GENE; GENE ACTIVATION; GENE LOSS; GENE REPRESSION; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; KLF1 GENE; LEUKEMOGENESIS; LYMPHATIC SYSTEM DISEASE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TET2 GENE; ANIMAL; CELL CULTURE; CELL LINEAGE; CELL TRANSFORMATION; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHYSIOLOGY;

ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HEMATOPOIETIC STEM CELLS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; MICE, KNOCKOUT; PROTO-ONCOGENE PROTEINS; RECEPTORS, ERYTHROPOIETIN;

EID: 84978680214     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3610     Document Type: Article

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