Myeloid PTEN deficiency impairs tumor-immune surveillance via immune-checkpoint inhibition

OncoImmunology

Volumn 5, Issue 7, 2016, Pages

  Kuttke, M ^a   Sahin, E ^a   Pisoni, J ^a   Percig, S ^a   Vogel, A ^a   Kraemmer, D ^a   Hanzl, L ^a   Brunner, J S ^a   Paar, H ^a   Soukup, K ^b   Halfmann, A ^b   Dohnal, A M ^b   Steiner, C W ^a   Bluml S ^a   Basilio, J ^a   Hochreiter, B ^a   Salzmann, M ^a   Hoesel, B ^a   Lametschwandtner, G ^c   Eferl, R ^d   Schmid, J A ^a   Schabbauer, G ^a   more..

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b St Anna Children's Cancer Research Institute   (Austria)

^c Apeiron Biologics Forschungs und Entwicklungsgesellschaft MbH   (Austria)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

CD8 +DCs; Colitis associated colon cancer; myeloid PI3K; tumor immune surveillance

Indexed keywords

CD11B ANTIGEN; CD3 ANTIGEN; CD45 ANTIGEN; CD8 ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA; LENTIVIRUS VECTOR; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 LIGAND 2; TRANSCRIPTOME;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; BONE MARROW CELL; CELL PROLIFERATION ASSAY; COLITIS; COLON CANCER; COLON MUCOSA; CONTROLLED STUDY; DENDRITIC CELL; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; IMMUNOMODULATION; IMMUNOSURVEILLANCE; LUCIFERASE ASSAY; MALE; MELANOMA CELL LINE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SINGLE CELL ANALYSIS; TUMOR GROWTH; TUMOR VOLUME;

EID: 84978115962     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.1080/2162402X.2016.1164918     Document Type: Article

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