Loss of phosphatase and tensin homolog in APCs impedes Th17-mediated autoimmune encephalomyelitis

Journal of Immunology

Volumn 195, Issue 6, 2015, Pages 2560-2570

  Sahin, Emine ^a   Brunner, Julia S ^a   Kral, Julia B ^a   Kuttke, Mario ^a   Hanzl, Leslie ^a   Datler, Hannes ^a   Paar, Hannah ^a   Neuwinger, Nick ^a   Saferding, Victoria ^a   Zinser, Elisabeth ^b   Halfmann, Angela ^c   Soukup, Klara ^c   Hainzl, Eva ^a   Lohmeyer, Tobias ^a   Niederreiter, Birgit ^a   Haider, Thomas ^a   Dohnal, Alexander M ^c   Krönke, Gerhard ^b   Blüml, Stephan ^a   Schabbauer, Gernot ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^c St Anna Children's Cancer Research Institute   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINASE 1; CD11B ANTIGEN; CD45 ANTIGEN; GAMMA INTERFERON; GLYCOPROTEIN P 15095; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 12P35; INTERLEUKIN 17; INTERLEUKIN 22; INTERLEUKIN 23; INTERLEUKIN 23P19; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE SYNTHASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; TRANSCRIPTION FACTOR T BET; ARG1 PROTEIN, MOUSE; ARGINASE; INTERLEUKIN DERIVATIVE; INTERLEUKIN-22; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN (35-55); PEPTIDE FRAGMENT; PTEN PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; BONE MARROW CELL; CD3+ T LYMPHOCYTE; CELL MIGRATION; CELL SPECIFICITY; CONTROLLED STUDY; CPG ISLAND; CYTOKINE PRODUCTION; DOWN REGULATION; ENZYME ACTIVATION; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; GENE EXPRESSION REGULATION; IMMUNOPATHOGENESIS; IMMUNOREGULATION; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; LYMPHOID CELL; MACROPHAGE; MOLECULAR DYNAMICS; MONOCYTE; MOUSE; NEUROPROTECTION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; T CELL POLARIZATION; TH17 CELL; UPREGULATION; ANIMAL; AUTOIMMUNITY; BIOSYNTHESIS; C57BL MOUSE; CELL DIFFERENTIATION; DENDRITIC CELL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; MACROPHAGE ACTIVATION; METABOLISM; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGENS, CD11C; ARGINASE; AUTOIMMUNITY; CELL DIFFERENTIATION; DENDRITIC CELLS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENZYME ACTIVATION; INTERLEUKIN-17; INTERLEUKINS; LYMPHOCYTE ACTIVATION; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELIN-OLIGODENDROCYTE GLYCOPROTEIN; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PEPTIDE FRAGMENTS; PHOSPHATIDYLINOSITOL 3-KINASES; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; TH17 CELLS;

EID: 84941770529     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1402511     Document Type: Article

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