메뉴 건너뛰기




Volumn 1, Issue 2, 2014, Pages 149-161

The versatile functions of Sox9 in development, stem cells, and human diseases

Author keywords

Development; Sox9; Stem cells; Transcription factor

Indexed keywords

TRANSCRIPTION FACTOR SOX9;

EID: 84978112122     PISSN: None     EISSN: 23523042     Source Type: Journal    
DOI: 10.1016/j.gendis.2014.09.004     Document Type: Review
Times cited : (274)

References (140)
  • 1
    • 80455174708 scopus 로고    scopus 로고
    • Stem cell self-renewal in intestinal crypt
    • Simons B.D., Clevers H. Stem cell self-renewal in intestinal crypt. Exp Cell Res 2011, 317:2719-2724.
    • (2011) Exp Cell Res , vol.317 , pp. 2719-2724
    • Simons, B.D.1    Clevers, H.2
  • 2
    • 84892459649 scopus 로고    scopus 로고
    • Adult stem cell niches: cellular and molecular components
    • Rezza A., Sennett R., Rendl M. Adult stem cell niches: cellular and molecular components. Curr Top Dev Biol 2014, 107:333-372.
    • (2014) Curr Top Dev Biol , vol.107 , pp. 333-372
    • Rezza, A.1    Sennett, R.2    Rendl, M.3
  • 3
    • 0025291407 scopus 로고
    • Normal structure and expression of Zfy genes in XY female mice mutant in Tdy
    • Gubbay J., Koopman P., Collignon J., Burgoyne P., Lovell-Badge R. Normal structure and expression of Zfy genes in XY female mice mutant in Tdy. Development 1990, 109:647-653.
    • (1990) Development , vol.109 , pp. 647-653
    • Gubbay, J.1    Koopman, P.2    Collignon, J.3    Burgoyne, P.4    Lovell-Badge, R.5
  • 4
    • 0025364886 scopus 로고
    • A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif
    • Sinclair A.H., Berta P., Palmer M.S., et al. A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif. Nature 1990, 346:240-244.
    • (1990) Nature , vol.346 , pp. 240-244
    • Sinclair, A.H.1    Berta, P.2    Palmer, M.S.3
  • 5
    • 76549111681 scopus 로고    scopus 로고
    • No backbone but lots of Sox: Invertebrate Sox genes
    • Phochanukul N., Russell S. No backbone but lots of Sox: Invertebrate Sox genes. Int J Biochem Cell Biol 2010, 42:453-464.
    • (2010) Int J Biochem Cell Biol , vol.42 , pp. 453-464
    • Phochanukul, N.1    Russell, S.2
  • 6
    • 0028589588 scopus 로고
    • Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9
    • Wagner T., Wirth J., Meyer J., et al. Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9. Cell 1994, 79:1111-1120.
    • (1994) Cell , vol.79 , pp. 1111-1120
    • Wagner, T.1    Wirth, J.2    Meyer, J.3
  • 7
    • 0033559518 scopus 로고    scopus 로고
    • From head to toes: the multiple facets of Sox proteins
    • Wegner M. From head to toes: the multiple facets of Sox proteins. Nucleic Acids Res 1999, 27:1409-1420.
    • (1999) Nucleic Acids Res , vol.27 , pp. 1409-1420
    • Wegner, M.1
  • 8
    • 40949084666 scopus 로고    scopus 로고
    • Sox9 and Sox10 influence survival and migration of oligodendrocyte precursors in the spinal cord by regulating PDGF receptor alpha expression
    • Finzsch M., Stolt C.C., Lommes P., Wegner M. Sox9 and Sox10 influence survival and migration of oligodendrocyte precursors in the spinal cord by regulating PDGF receptor alpha expression. Development 2008, 135:637-646.
    • (2008) Development , vol.135 , pp. 637-646
    • Finzsch, M.1    Stolt, C.C.2    Lommes, P.3    Wegner, M.4
  • 9
    • 33748202079 scopus 로고    scopus 로고
    • Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence
    • Kellerer S., Schreiner S., Stolt C.C., Scholz S., Bosl M.R., Wegner M. Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence. Development 2006, 133:2875-2886.
    • (2006) Development , vol.133 , pp. 2875-2886
    • Kellerer, S.1    Schreiner, S.2    Stolt, C.C.3    Scholz, S.4    Bosl, M.R.5    Wegner, M.6
  • 10
    • 3042705838 scopus 로고    scopus 로고
    • Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy
    • Stolt C.C., Lommes P., Friedrich R.P., Wegner M. Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy. Development 2004, 131:2349-2358.
    • (2004) Development , vol.131 , pp. 2349-2358
    • Stolt, C.C.1    Lommes, P.2    Friedrich, R.P.3    Wegner, M.4
  • 11
    • 0034067651 scopus 로고    scopus 로고
    • Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase A enhances SOX9's ability to transactivate a Col2a1 chondrocyte-specific enhancer
    • Huang W., Zhou X., Lefebvre V., de Crombrugghe B. Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase A enhances SOX9's ability to transactivate a Col2a1 chondrocyte-specific enhancer. Mol Cell Biol 2000, 20:4149-4158.
    • (2000) Mol Cell Biol , vol.20 , pp. 4149-4158
    • Huang, W.1    Zhou, X.2    Lefebvre, V.3    de Crombrugghe, B.4
  • 12
    • 84874247173 scopus 로고    scopus 로고
    • Phosphorylation of Sox9 is required for neural crest delamination and is regulated downstream of BMP and canonical Wnt signaling
    • Liu J.A., Wu M.H., Yan C.H., et al. Phosphorylation of Sox9 is required for neural crest delamination and is regulated downstream of BMP and canonical Wnt signaling. Proc Natl Acad Sci U S A 2013, 110:2882-2887.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 2882-2887
    • Liu, J.A.1    Wu, M.H.2    Yan, C.H.3
  • 13
    • 27644490228 scopus 로고    scopus 로고
    • SoxE factors function equivalently during neural crest and inner ear development and their activity is regulated by SUMOylation
    • Taylor K.M., Labonne C. SoxE factors function equivalently during neural crest and inner ear development and their activity is regulated by SUMOylation. Dev Cell 2005, 9:593-603.
    • (2005) Dev Cell , vol.9 , pp. 593-603
    • Taylor, K.M.1    Labonne, C.2
  • 15
    • 33744915576 scopus 로고    scopus 로고
    • Interactions between PIAS proteins and SOX9 result in an increase in the cellular concentrations of SOX9
    • Hattori T., Eberspaecher H., Lu J., et al. Interactions between PIAS proteins and SOX9 result in an increase in the cellular concentrations of SOX9. J Biol Chem 2006, 281:14417-14428.
    • (2006) J Biol Chem , vol.281 , pp. 14417-14428
    • Hattori, T.1    Eberspaecher, H.2    Lu, J.3
  • 16
    • 34748901397 scopus 로고    scopus 로고
    • PIAS1 interacts with and represses SOX9 transactivation activity
    • Oh H.J., Kido T., Lau Y.F. PIAS1 interacts with and represses SOX9 transactivation activity. Mol Reprod Dev 2007, 74:1446-1455.
    • (2007) Mol Reprod Dev , vol.74 , pp. 1446-1455
    • Oh, H.J.1    Kido, T.2    Lau, Y.F.3
  • 17
    • 63649138643 scopus 로고    scopus 로고
    • MiR-124 regulates adult neurogenesis in the subventricular zone stem cell niche
    • Cheng L.C., Pastrana E., Tavazoie M., Doetsch F. miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche. Nat Neurosci 2009, 12:399-408.
    • (2009) Nat Neurosci , vol.12 , pp. 399-408
    • Cheng, L.C.1    Pastrana, E.2    Tavazoie, M.3    Doetsch, F.4
  • 18
    • 34748900267 scopus 로고    scopus 로고
    • Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells
    • Lu Y., Thomson J.M., Wong H.Y., Hammond S.M., Hogan B.L. Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells. Dev Biol 2007, 310:442-453.
    • (2007) Dev Biol , vol.310 , pp. 442-453
    • Lu, Y.1    Thomson, J.M.2    Wong, H.Y.3    Hammond, S.M.4    Hogan, B.L.5
  • 19
    • 84866100301 scopus 로고    scopus 로고
    • Macro view of microRNA function in osteoarthritis
    • Miyaki S., Asahara H. Macro view of microRNA function in osteoarthritis. Nat Rev Rheumatol 2012, 8:543-552.
    • (2012) Nat Rev Rheumatol , vol.8 , pp. 543-552
    • Miyaki, S.1    Asahara, H.2
  • 21
    • 84890283576 scopus 로고    scopus 로고
    • E6-AP/UBE3A protein acts as a ubiquitin ligase toward SOX9 protein
    • Hattori T., Kishino T., Stephen S., et al. E6-AP/UBE3A protein acts as a ubiquitin ligase toward SOX9 protein. J Biol Chem 2013, 288:35138-35148.
    • (2013) J Biol Chem , vol.288 , pp. 35138-35148
    • Hattori, T.1    Kishino, T.2    Stephen, S.3
  • 22
    • 0034175998 scopus 로고    scopus 로고
    • Pairing SOX off: with partners in the regulation of embryonic development
    • Kamachi Y., Uchikawa M., Kondoh H. Pairing SOX off: with partners in the regulation of embryonic development. Trends Genet 2000, 16:182-187.
    • (2000) Trends Genet , vol.16 , pp. 182-187
    • Kamachi, Y.1    Uchikawa, M.2    Kondoh, H.3
  • 23
    • 0042703900 scopus 로고    scopus 로고
    • Dimerization of SOX9 is required for chondrogenesis, but not for sex determination
    • Bernard P., Tang P., Liu S., Dewing P., Harley V.R., Vilain E. Dimerization of SOX9 is required for chondrogenesis, but not for sex determination. Hum Mol Genet 2003, 12:1755-1765.
    • (2003) Hum Mol Genet , vol.12 , pp. 1755-1765
    • Bernard, P.1    Tang, P.2    Liu, S.3    Dewing, P.4    Harley, V.R.5    Vilain, E.6
  • 24
    • 81755183071 scopus 로고    scopus 로고
    • SOX9 governs differentiation stage-specific gene expression in growth plate chondrocytes via direct concomitant transactivation and repression
    • Leung V.Y., Gao B., Leung K.K., et al. SOX9 governs differentiation stage-specific gene expression in growth plate chondrocytes via direct concomitant transactivation and repression. PLoS Genet 2011, 7:e1002356.
    • (2011) PLoS Genet , vol.7 , pp. e1002356
    • Leung, V.Y.1    Gao, B.2    Leung, K.K.3
  • 25
    • 8444233948 scopus 로고    scopus 로고
    • The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage
    • Ikeda T., Kamekura S., Mabuchi A., et al. The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage. Arthritis Rheum 2004, 50:3561-3573.
    • (2004) Arthritis Rheum , vol.50 , pp. 3561-3573
    • Ikeda, T.1    Kamekura, S.2    Mabuchi, A.3
  • 26
    • 45149093155 scopus 로고    scopus 로고
    • Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer
    • Sekido R., Lovell-Badge R. Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer. Nature 2008, 453:930-934.
    • (2008) Nature , vol.453 , pp. 930-934
    • Sekido, R.1    Lovell-Badge, R.2
  • 27
    • 37249001756 scopus 로고    scopus 로고
    • Skeletal dysplasias and the growth plate
    • Alman B.A. Skeletal dysplasias and the growth plate. Clin Genet 2008, 73:24-30.
    • (2008) Clin Genet , vol.73 , pp. 24-30
    • Alman, B.A.1
  • 29
    • 77950345356 scopus 로고    scopus 로고
    • SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification
    • Hattori T., Muller C., Gebhard S., et al. SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification. Development 2010, 137:901-911.
    • (2010) Development , vol.137 , pp. 901-911
    • Hattori, T.1    Muller, C.2    Gebhard, S.3
  • 30
    • 0031003272 scopus 로고    scopus 로고
    • SOX9 directly regulates the type-II collagen gene
    • Bell D.M., Leung K.K., Wheatley S.C., et al. SOX9 directly regulates the type-II collagen gene. Nat Genet 1997, 16:174-178.
    • (1997) Nat Genet , vol.16 , pp. 174-178
    • Bell, D.M.1    Leung, K.K.2    Wheatley, S.C.3
  • 31
    • 0030899814 scopus 로고    scopus 로고
    • SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene
    • Lefebvre V., Huang W., Harley V.R., Goodfellow P.N., de Crombrugghe B. SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene. Mol Cell Biol 1997, 17:2336-2346.
    • (1997) Mol Cell Biol , vol.17 , pp. 2336-2346
    • Lefebvre, V.1    Huang, W.2    Harley, V.R.3    Goodfellow, P.N.4    de Crombrugghe, B.5
  • 32
    • 12444273295 scopus 로고    scopus 로고
    • Potential use of Sox9 gene therapy for intervertebral degenerative disc disease
    • Paul R., Haydon R.C., Cheng H., et al. Potential use of Sox9 gene therapy for intervertebral degenerative disc disease. Spine 2003, 28:755-763.
    • (2003) Spine , vol.28 , pp. 755-763
    • Paul, R.1    Haydon, R.C.2    Cheng, H.3
  • 33
    • 34247517336 scopus 로고    scopus 로고
    • Misexpression of Sox9 in mouse limb bud mesenchyme induces polydactyly and rescues hypodactyly mice
    • Akiyama H., Stadler H.S., Martin J.F., et al. Misexpression of Sox9 in mouse limb bud mesenchyme induces polydactyly and rescues hypodactyly mice. Matrix Biol 2007, 26:224-233.
    • (2007) Matrix Biol , vol.26 , pp. 224-233
    • Akiyama, H.1    Stadler, H.S.2    Martin, J.F.3
  • 34
    • 0033567213 scopus 로고    scopus 로고
    • Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation
    • St-Jacques B., Hammerschmidt M., McMahon A.P. Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation. Genes Dev 1999, 13(16):2072-2086.
    • (1999) Genes Dev , vol.13 , Issue.16 , pp. 2072-2086
    • St-Jacques, B.1    Hammerschmidt, M.2    McMahon, A.P.3
  • 35
    • 84865536179 scopus 로고    scopus 로고
    • Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans
    • Pritchett J., Harvey E., Athwal V., et al. Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans. Hepatology 2012, 56:1108-1116.
    • (2012) Hepatology , vol.56 , pp. 1108-1116
    • Pritchett, J.1    Harvey, E.2    Athwal, V.3
  • 36
    • 46549083928 scopus 로고    scopus 로고
    • Control of chondrogenesis by the transcription factor Sox9
    • Akiyama H. Control of chondrogenesis by the transcription factor Sox9. Mod Rheumatol 2008, 18:213-219.
    • (2008) Mod Rheumatol , vol.18 , pp. 213-219
    • Akiyama, H.1
  • 37
    • 59149089747 scopus 로고    scopus 로고
    • Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus
    • Topol L., Chen W., Song H., Day T.F., Yang Y. Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus. J Biol Chem 2009, 284:3323-3333.
    • (2009) J Biol Chem , vol.284 , pp. 3323-3333
    • Topol, L.1    Chen, W.2    Song, H.3    Day, T.F.4    Yang, Y.5
  • 38
    • 2442514340 scopus 로고    scopus 로고
    • Interactions between Sox9 and beta-catenin control chondrocyte differentiation
    • Akiyama H., Lyons J.P., Mori-Akiyama Y., et al. Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev 2004, 18:1072-1087.
    • (2004) Genes Dev , vol.18 , pp. 1072-1087
    • Akiyama, H.1    Lyons, J.P.2    Mori-Akiyama, Y.3
  • 39
    • 33646137784 scopus 로고    scopus 로고
    • Cooperative action of Sox9, Snail2 and PKA signaling in early neural crest development
    • Sakai D., Suzuki T., Osumi N., Wakamatsu Y. Cooperative action of Sox9, Snail2 and PKA signaling in early neural crest development. Development 2006, 133:1323-1333.
    • (2006) Development , vol.133 , pp. 1323-1333
    • Sakai, D.1    Suzuki, T.2    Osumi, N.3    Wakamatsu, Y.4
  • 40
    • 4644291070 scopus 로고    scopus 로고
    • Early requirement of the transcriptional activator Sox9 for neural crest specification in Xenopus
    • Lee Y.H., Aoki Y., Hong C.S., Saint-Germain N., Credidio C., Saint-Jeannet J.P. Early requirement of the transcriptional activator Sox9 for neural crest specification in Xenopus. Dev Biol 2004, 275:93-103.
    • (2004) Dev Biol , vol.275 , pp. 93-103
    • Lee, Y.H.1    Aoki, Y.2    Hong, C.S.3    Saint-Germain, N.4    Credidio, C.5    Saint-Jeannet, J.P.6
  • 41
    • 20244364236 scopus 로고    scopus 로고
    • Wnt signalling induces maturation of Paneth cells in intestinal crypts
    • van Es J.H., Jay P., Gregorieff A., et al. Wnt signalling induces maturation of Paneth cells in intestinal crypts. Nat Cell Biol 2005, 7:381-386.
    • (2005) Nat Cell Biol , vol.7 , pp. 381-386
    • van Es, J.H.1    Jay, P.2    Gregorieff, A.3
  • 42
    • 0028135336 scopus 로고
    • Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene
    • Foster J.W., Dominguez-Steglich M.A., Guioli S., et al. Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene. Nature 1994, 372:525-530.
    • (1994) Nature , vol.372 , pp. 525-530
    • Foster, J.W.1    Dominguez-Steglich, M.A.2    Guioli, S.3
  • 43
    • 0032725866 scopus 로고    scopus 로고
    • Autosomal XX sex reversal caused by duplication of SOX9
    • Huang B., Wang S., Ning Y., Lamb A.N., Bartley J. Autosomal XX sex reversal caused by duplication of SOX9. Am J Med Genet 1999, 87:349-353.
    • (1999) Am J Med Genet , vol.87 , pp. 349-353
    • Huang, B.1    Wang, S.2    Ning, Y.3    Lamb, A.N.4    Bartley, J.5
  • 44
    • 84889588398 scopus 로고    scopus 로고
    • Sox9-related signaling controls zebrafish juvenile ovary-testis transformation
    • Sun D., Zhang Y., Wang C., Hua X., Zhang X.A., Yan J. Sox9-related signaling controls zebrafish juvenile ovary-testis transformation. Cell Death Dis 2013, 4:e930.
    • (2013) Cell Death Dis , vol.4 , pp. e930
    • Sun, D.1    Zhang, Y.2    Wang, C.3    Hua, X.4    Zhang, X.A.5    Yan, J.6
  • 45
    • 34249854973 scopus 로고    scopus 로고
    • SOX9 regulates prostaglandin D synthase gene transcription invivo to ensure testis development
    • Wilhelm D., Hiramatsu R., Mizusaki H., et al. SOX9 regulates prostaglandin D synthase gene transcription invivo to ensure testis development. J Biol Chem 2007, 282:10553-10560.
    • (2007) J Biol Chem , vol.282 , pp. 10553-10560
    • Wilhelm, D.1    Hiramatsu, R.2    Mizusaki, H.3
  • 46
    • 80052044795 scopus 로고    scopus 로고
    • SOX9 and SF1 are involved in cyclic AMP-mediated upregulation of anti-Mullerian gene expression in the testicular prepubertal Sertoli cell line SMAT1
    • Lasala C., Schteingart H.F., Arouche N., et al. SOX9 and SF1 are involved in cyclic AMP-mediated upregulation of anti-Mullerian gene expression in the testicular prepubertal Sertoli cell line SMAT1. Am J Physiol Endocrinol Metab 2011, 301:E539-E547.
    • (2011) Am J Physiol Endocrinol Metab , vol.301 , pp. E539-E547
    • Lasala, C.1    Schteingart, H.F.2    Arouche, N.3
  • 47
    • 60849087698 scopus 로고    scopus 로고
    • Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8
    • Barrionuevo F., Georg I., Scherthan H., et al. Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8. Dev Biol 2009, 327:301-312.
    • (2009) Dev Biol , vol.327 , pp. 301-312
    • Barrionuevo, F.1    Georg, I.2    Scherthan, H.3
  • 48
    • 0031880363 scopus 로고    scopus 로고
    • Early expression of AMH in chicken embryonic gonads precedes testicular SOX9 expression
    • Oreal E., Pieau C., Mattei M.G., et al. Early expression of AMH in chicken embryonic gonads precedes testicular SOX9 expression. Dev Dyn 1998, 212:522-532.
    • (1998) Dev Dyn , vol.212 , pp. 522-532
    • Oreal, E.1    Pieau, C.2    Mattei, M.G.3
  • 49
    • 24744472060 scopus 로고    scopus 로고
    • Regulation of Amh during sexdetermination in chickens: Sox gene expression in maleand female gonads
    • Takada S., Mano H., Koopman P. Regulation of Amh during sexdetermination in chickens: Sox gene expression in maleand female gonads. Cell Mol Life Sci 2005, 62:2140-2146.
    • (2005) Cell Mol Life Sci , vol.62 , pp. 2140-2146
    • Takada, S.1    Mano, H.2    Koopman, P.3
  • 50
    • 2342630451 scopus 로고    scopus 로고
    • Essential role of Sox9 in the pathway that controls formation of cardiac valves and septa
    • Akiyama H., Chaboissier M.C., Behringer R.R., et al. Essential role of Sox9 in the pathway that controls formation of cardiac valves and septa. Proc Natl Acad Sci U S A 2004, 101:6502-6507.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 6502-6507
    • Akiyama, H.1    Chaboissier, M.C.2    Behringer, R.R.3
  • 51
    • 34247249338 scopus 로고    scopus 로고
    • Sox9 is required for precursor cell expansion and extracellular matrix organization during mouse heart valve development
    • Lincoln J., Kist R., Scherer G., Yutzey K.E. Sox9 is required for precursor cell expansion and extracellular matrix organization during mouse heart valve development. Dev Biol 2007, 305:120-132.
    • (2007) Dev Biol , vol.305 , pp. 120-132
    • Lincoln, J.1    Kist, R.2    Scherer, G.3    Yutzey, K.E.4
  • 52
    • 79952455908 scopus 로고    scopus 로고
    • Understanding the role of SOX9 in acquired diseases: lessons from development
    • Pritchett J., Athwal V., Roberts N., Hanley N.A., Hanley K.P. Understanding the role of SOX9 in acquired diseases: lessons from development. Trends Mol Med 2011, 17:166-174.
    • (2011) Trends Mol Med , vol.17 , pp. 166-174
    • Pritchett, J.1    Athwal, V.2    Roberts, N.3    Hanley, N.A.4    Hanley, K.P.5
  • 53
    • 4444286866 scopus 로고    scopus 로고
    • SOX9 specifies the pyloric sphincter epithelium through mesenchymal-epithelial signals
    • Moniot B., Biau S., Faure S., et al. SOX9 specifies the pyloric sphincter epithelium through mesenchymal-epithelial signals. Development 2004, 131:3795-3804.
    • (2004) Development , vol.131 , pp. 3795-3804
    • Moniot, B.1    Biau, S.2    Faure, S.3
  • 54
    • 14544301011 scopus 로고    scopus 로고
    • Sox9 and Nkx2.5 determine the pyloric sphincter epithelium under the control of BMP signaling
    • Theodosiou N.A., Tabin C.J. Sox9 and Nkx2.5 determine the pyloric sphincter epithelium under the control of BMP signaling. Dev Biol 2005, 279:481-490.
    • (2005) Dev Biol , vol.279 , pp. 481-490
    • Theodosiou, N.A.1    Tabin, C.J.2
  • 55
    • 84875796343 scopus 로고    scopus 로고
    • A critical role for Sox9 in notch-induced astrogliogenesis and stem cell maintenance
    • Martini S., Bernoth K., Main H., et al. A critical role for Sox9 in notch-induced astrogliogenesis and stem cell maintenance. Stem Cells 2013, 31:741-751.
    • (2013) Stem Cells , vol.31 , pp. 741-751
    • Martini, S.1    Bernoth, K.2    Main, H.3
  • 56
    • 77957285454 scopus 로고    scopus 로고
    • SOX9 induces and maintains neural stem cells
    • Scott C.E., Wynn S.L., Sesay A., et al. SOX9 induces and maintains neural stem cells. Nat Neurosci 2010, 13:1181-1189.
    • (2010) Nat Neurosci , vol.13 , pp. 1181-1189
    • Scott, C.E.1    Wynn, S.L.2    Sesay, A.3
  • 57
    • 84859630910 scopus 로고    scopus 로고
    • Sox9 and NFIA coordinate a transcriptional regulatory cascade during the initiation of gliogenesis
    • Kang P., Lee H.K., Glasgow S.M., et al. Sox9 and NFIA coordinate a transcriptional regulatory cascade during the initiation of gliogenesis. Neuron 2012, 74:79-94.
    • (2012) Neuron , vol.74 , pp. 79-94
    • Kang, P.1    Lee, H.K.2    Glasgow, S.M.3
  • 58
    • 76549123335 scopus 로고    scopus 로고
    • SoxE function in vertebrate nervous system development
    • Stolt C.C., Wegner M. SoxE function in vertebrate nervous system development. Int J Biochem Cell Biol 2010, 42:437-440.
    • (2010) Int J Biochem Cell Biol , vol.42 , pp. 437-440
    • Stolt, C.C.1    Wegner, M.2
  • 59
    • 0037663384 scopus 로고    scopus 로고
    • The Sox9 transcription factor determines glial fate choice in the developing spinal cord
    • Stolt C.C., Lommes P., Sock E., Chaboissier M.C., Schedl A., Wegner M. The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev 2003, 17:1677-1689.
    • (2003) Genes Dev , vol.17 , pp. 1677-1689
    • Stolt, C.C.1    Lommes, P.2    Sock, E.3    Chaboissier, M.C.4    Schedl, A.5    Wegner, M.6
  • 60
    • 22144470750 scopus 로고    scopus 로고
    • Regulatory mechanisms for neural crest formation
    • Sakai D., Wakamatsu Y. Regulatory mechanisms for neural crest formation. Cells Tissues Organs 2005, 179:24-35.
    • (2005) Cells Tissues Organs , vol.179 , pp. 24-35
    • Sakai, D.1    Wakamatsu, Y.2
  • 61
    • 0346121540 scopus 로고    scopus 로고
    • Neural crest development is regulated by the transcription factor Sox9
    • Cheung M., Briscoe J. Neural crest development is regulated by the transcription factor Sox9. Development 2003, 130:5681-5693.
    • (2003) Development , vol.130 , pp. 5681-5693
    • Cheung, M.1    Briscoe, J.2
  • 62
  • 63
    • 23244443556 scopus 로고    scopus 로고
    • Sox9 is essential for outer root sheath differentiation and the formation of the hair stem cell compartment
    • Vidal V.P., Chaboissier M.C., Lutzkendorf S., et al. Sox9 is essential for outer root sheath differentiation and the formation of the hair stem cell compartment. Curr Biol 2005, 15:1340-1351.
    • (2005) Curr Biol , vol.15 , pp. 1340-1351
    • Vidal, V.P.1    Chaboissier, M.C.2    Lutzkendorf, S.3
  • 64
    • 48649085299 scopus 로고    scopus 로고
    • Hair follicle stem cells are specified and function in early skin morphogenesis
    • Nowak J.A., Polak L., Pasolli H.A., Fuchs E. Hair follicle stem cells are specified and function in early skin morphogenesis. Cell Stem Cell 2008, 3:33-43.
    • (2008) Cell Stem Cell , vol.3 , pp. 33-43
    • Nowak, J.A.1    Polak, L.2    Pasolli, H.A.3    Fuchs, E.4
  • 65
    • 50249148352 scopus 로고    scopus 로고
    • Sox9 is expressed in mouse multipotent retinal progenitor cells and functions in Muller glial cell development
    • Poche R.A., Furuta Y., Chaboissier M.C., Schedl A., Behringer R.R. Sox9 is expressed in mouse multipotent retinal progenitor cells and functions in Muller glial cell development. J Comp Neurol 2008, 510:237-250.
    • (2008) J Comp Neurol , vol.510 , pp. 237-250
    • Poche, R.A.1    Furuta, Y.2    Chaboissier, M.C.3    Schedl, A.4    Behringer, R.R.5
  • 66
    • 77956244305 scopus 로고    scopus 로고
    • SOX9, through interaction with microphthalmia-associated transcription factor (MITF) and OTX2, regulates BEST1 expression in the retinal pigment epithelium
    • Masuda T., Esumi N. SOX9, through interaction with microphthalmia-associated transcription factor (MITF) and OTX2, regulates BEST1 expression in the retinal pigment epithelium. J Biol Chem 2010, 285:26933-26944.
    • (2010) J Biol Chem , vol.285 , pp. 26933-26944
    • Masuda, T.1    Esumi, N.2
  • 67
    • 84873670539 scopus 로고    scopus 로고
    • The expression of NOTCH2, HES1 and SOX9 during mouse retinal development
    • Zhu M.Y., Gasperowicz M., Chow R.L. The expression of NOTCH2, HES1 and SOX9 during mouse retinal development. Gene Expr Patterns 2013, 13:78-83.
    • (2013) Gene Expr Patterns , vol.13 , pp. 78-83
    • Zhu, M.Y.1    Gasperowicz, M.2    Chow, R.L.3
  • 68
    • 69749106313 scopus 로고    scopus 로고
    • The group E Sox genes Sox8 and Sox9 are regulated by Notch signaling and are required for Muller glial cell development in mouse retina
    • Muto A., Iida A., Satoh S., Watanabe S. The group E Sox genes Sox8 and Sox9 are regulated by Notch signaling and are required for Muller glial cell development in mouse retina. Exp Eye Res 2009, 89:549-558.
    • (2009) Exp Eye Res , vol.89 , pp. 549-558
    • Muto, A.1    Iida, A.2    Satoh, S.3    Watanabe, S.4
  • 70
    • 42649121930 scopus 로고    scopus 로고
    • Sox9 is required for invagination of the otic placode in mice
    • Barrionuevo F., Naumann A., Bagheri-Fam S., et al. Sox9 is required for invagination of the otic placode in mice. Dev Biol 2008, 317:213-224.
    • (2008) Dev Biol , vol.317 , pp. 213-224
    • Barrionuevo, F.1    Naumann, A.2    Bagheri-Fam, S.3
  • 71
    • 84888051783 scopus 로고    scopus 로고
    • The role of SOX9 transcription factor in pancreatic and duodenal development
    • Belo J., Krishnamurthy M., Oakie A., Wang R. The role of SOX9 transcription factor in pancreatic and duodenal development. Stem Cells Dev 2013, 22:2935-2943.
    • (2013) Stem Cells Dev , vol.22 , pp. 2935-2943
    • Belo, J.1    Krishnamurthy, M.2    Oakie, A.3    Wang, R.4
  • 72
    • 33846910410 scopus 로고    scopus 로고
    • SOX9 is required for maintenance of the pancreatic progenitor cell pool
    • Seymour P.A., Freude K.K., Tran M.N., et al. SOX9 is required for maintenance of the pancreatic progenitor cell pool. Proc Natl Acad Sci U S A 2007, 104:1865-1870.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 1865-1870
    • Seymour, P.A.1    Freude, K.K.2    Tran, M.N.3
  • 73
    • 0035996994 scopus 로고    scopus 로고
    • Novel SOX9 expression during human pancreas development correlates to abnormalities in Campomelic dysplasia
    • Piper K., Ball S.G., Keeling J.W., Mansoor S., Wilson D.I., Hanley N.A. Novel SOX9 expression during human pancreas development correlates to abnormalities in Campomelic dysplasia. Mech Dev 2002, 116:223-226.
    • (2002) Mech Dev , vol.116 , pp. 223-226
    • Piper, K.1    Ball, S.G.2    Keeling, J.W.3    Mansoor, S.4    Wilson, D.I.5    Hanley, N.A.6
  • 74
    • 53649102798 scopus 로고    scopus 로고
    • A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation
    • Seymour P.A., Freude K.K., Dubois C.L., Shih H.P., Patel N.A., Sander M. A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation. Dev Biol 2008, 323:19-30.
    • (2008) Dev Biol , vol.323 , pp. 19-30
    • Seymour, P.A.1    Freude, K.K.2    Dubois, C.L.3    Shih, H.P.4    Patel, N.A.5    Sander, M.6
  • 75
    • 84863088235 scopus 로고    scopus 로고
    • A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation
    • Shih H.P., Kopp J.L., Sandhu M., et al. A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation. Development 2012, 139:2488-2499.
    • (2012) Development , vol.139 , pp. 2488-2499
    • Shih, H.P.1    Kopp, J.L.2    Sandhu, M.3
  • 76
    • 84877106062 scopus 로고    scopus 로고
    • Sox9 and programming of liver and pancreatic progenitors
    • Kawaguchi Y. Sox9 and programming of liver and pancreatic progenitors. J Clin Invest 2013, 123:1881-1886.
    • (2013) J Clin Invest , vol.123 , pp. 1881-1886
    • Kawaguchi, Y.1
  • 77
    • 84855417413 scopus 로고    scopus 로고
    • Biliary tree stem/progenitor cells in glands of extrahepatic and intraheptic bile ducts: an anatomical in situ study yielding evidence of maturational lineages
    • Carpino G., Cardinale V., Onori P., et al. Biliary tree stem/progenitor cells in glands of extrahepatic and intraheptic bile ducts: an anatomical in situ study yielding evidence of maturational lineages. J Anat 2012, 220:186-199.
    • (2012) J Anat , vol.220 , pp. 186-199
    • Carpino, G.1    Cardinale, V.2    Onori, P.3
  • 78
    • 80053610191 scopus 로고    scopus 로고
    • Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells
    • 1432-1438, 1438 e1431-1434
    • Carpentier R., Suner R.E., van Hul N., et al. Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells. Gastroenterology 2011, 141(4). 1432-1438, 1438 e1431-1434.
    • (2011) Gastroenterology , vol.141 , Issue.4
    • Carpentier, R.1    Suner, R.E.2    van Hul, N.3
  • 79
    • 78651228289 scopus 로고    scopus 로고
    • Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine
    • Furuyama K., Kawaguchi Y., Akiyama H., et al. Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine. Nat Genet 2011, 43:34-41.
    • (2011) Nat Genet , vol.43 , pp. 34-41
    • Furuyama, K.1    Kawaguchi, Y.2    Akiyama, H.3
  • 80
    • 66149104013 scopus 로고    scopus 로고
    • Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9
    • Antoniou A., Raynaud P., Cordi S., et al. Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9. Gastroenterology 2009, 136:2325-2333.
    • (2009) Gastroenterology , vol.136 , pp. 2325-2333
    • Antoniou, A.1    Raynaud, P.2    Cordi, S.3
  • 81
    • 9644307844 scopus 로고    scopus 로고
    • The role of notch signaling in the development of intrahepatic bile ducts
    • Kodama Y., Hijikata M., Kageyama R., Shimotohno K., Chiba T. The role of notch signaling in the development of intrahepatic bile ducts. Gastroenterology 2004, 127:1775-1786.
    • (2004) Gastroenterology , vol.127 , pp. 1775-1786
    • Kodama, Y.1    Hijikata, M.2    Kageyama, R.3    Shimotohno, K.4    Chiba, T.5
  • 82
    • 34547549553 scopus 로고    scopus 로고
    • SOX9 is required for the differentiation of paneth cells in the intestinal epithelium
    • Mori-Akiyama Y., van den Born M., van Es J.H., et al. SOX9 is required for the differentiation of paneth cells in the intestinal epithelium. Gastroenterology 2007, 133:539-546.
    • (2007) Gastroenterology , vol.133 , pp. 539-546
    • Mori-Akiyama, Y.1    van den Born, M.2    van Es, J.H.3
  • 83
    • 34547956892 scopus 로고    scopus 로고
    • Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium
    • Bastide P., Darido C., Pannequin J., et al. Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium. J Cell Biol 2007, 178:635-648.
    • (2007) J Cell Biol , vol.178 , pp. 635-648
    • Bastide, P.1    Darido, C.2    Pannequin, J.3
  • 85
    • 0029033699 scopus 로고
    • A clinical and genetic study of campomelic dysplasia
    • Mansour S., Hall C.M., Pembrey M.E., Young I.D. A clinical and genetic study of campomelic dysplasia. J Med Genet 1995, 32:415-420.
    • (1995) J Med Genet , vol.32 , pp. 415-420
    • Mansour, S.1    Hall, C.M.2    Pembrey, M.E.3    Young, I.D.4
  • 86
    • 13944260928 scopus 로고    scopus 로고
    • Normal lung development and function after Sox9 inactivation in the respiratory epithelium
    • Perl A.K., Kist R., Shan Z., Scherer G., Whitsett J.A. Normal lung development and function after Sox9 inactivation in the respiratory epithelium. Genesis 2005, 41:23-32.
    • (2005) Genesis , vol.41 , pp. 23-32
    • Perl, A.K.1    Kist, R.2    Shan, Z.3    Scherer, G.4    Whitsett, J.A.5
  • 87
    • 84887308205 scopus 로고    scopus 로고
    • Lung epithelial branching program antagonizes alveolar differentiation
    • Chang D.R., Martinez Alanis D., Miller R.K., et al. Lung epithelial branching program antagonizes alveolar differentiation. Proc Natl Acad Sci U S A 2013, 110:18042-18051.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 18042-18051
    • Chang, D.R.1    Martinez Alanis, D.2    Miller, R.K.3
  • 88
    • 84888112949 scopus 로고    scopus 로고
    • Sox9 plays multiple roles in the lung epithelium during branching morphogenesis
    • Rockich B.E., Hrycaj S.M., Shih H.P., et al. Sox9 plays multiple roles in the lung epithelium during branching morphogenesis. Proc Natl Acad Sci U S A 2013, 110:E4456-E4464.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. E4456-E4464
    • Rockich, B.E.1    Hrycaj, S.M.2    Shih, H.P.3
  • 89
    • 84888080138 scopus 로고    scopus 로고
    • Lung mesenchymal expression of Sox9 plays a critical role in tracheal development
    • Turcatel G., Rubin N., Menke D.B., Martin G., Shi W., Warburton D. Lung mesenchymal expression of Sox9 plays a critical role in tracheal development. BMC Biol 2013, 11:117.
    • (2013) BMC Biol , vol.11 , pp. 117
    • Turcatel, G.1    Rubin, N.2    Menke, D.B.3    Martin, G.4    Shi, W.5    Warburton, D.6
  • 90
    • 84899707851 scopus 로고    scopus 로고
    • Transcription factor SOX9 plays a key role in the regulation of visual cycle gene expression in the retinal pigment epithelium
    • Masuda T., Wahlin K., Wan J., et al. Transcription factor SOX9 plays a key role in the regulation of visual cycle gene expression in the retinal pigment epithelium. J Biol Chem 2014, 289:12908-12921.
    • (2014) J Biol Chem , vol.289 , pp. 12908-12921
    • Masuda, T.1    Wahlin, K.2    Wan, J.3
  • 91
    • 31044432919 scopus 로고    scopus 로고
    • Gene expression profiling gets to the root of human hair follicle stem cells
    • Cotsarelis G. Gene expression profiling gets to the root of human hair follicle stem cells. J Clin Invest 2006, 116:19-22.
    • (2006) J Clin Invest , vol.116 , pp. 19-22
    • Cotsarelis, G.1
  • 92
    • 84893942254 scopus 로고    scopus 로고
    • SOX9: a stem cell transcriptional regulator of secreted niche signaling factors
    • Kadaja M., Keyes B.E., Lin M., et al. SOX9: a stem cell transcriptional regulator of secreted niche signaling factors. Genes Dev 2014, 28:328-341.
    • (2014) Genes Dev , vol.28 , pp. 328-341
    • Kadaja, M.1    Keyes, B.E.2    Lin, M.3
  • 93
    • 0038046074 scopus 로고    scopus 로고
    • Sox10 regulates the development of neural crest-derived melanocytes in Xenopus
    • Aoki Y., Saint-Germain N., Gyda M., et al. Sox10 regulates the development of neural crest-derived melanocytes in Xenopus. Dev Biol 2003, 259:19-33.
    • (2003) Dev Biol , vol.259 , pp. 19-33
    • Aoki, Y.1    Saint-Germain, N.2    Gyda, M.3
  • 94
    • 35348813142 scopus 로고    scopus 로고
    • SOX9 is a key player in ultraviolet B-induced melanocyte differentiation and pigmentation
    • Passeron T., Valencia J.C., Bertolotto C., et al. SOX9 is a key player in ultraviolet B-induced melanocyte differentiation and pigmentation. Proc Natl Acad Sci U S A 2007, 104:13984-13989.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 13984-13989
    • Passeron, T.1    Valencia, J.C.2    Bertolotto, C.3
  • 95
    • 36549004644 scopus 로고    scopus 로고
    • Tracking down the stem cells of the intestine: strategies to identify adult stem cells
    • Barker N., Clevers H. Tracking down the stem cells of the intestine: strategies to identify adult stem cells. Gastroenterology 2007, 133:1755-1760.
    • (2007) Gastroenterology , vol.133 , pp. 1755-1760
    • Barker, N.1    Clevers, H.2
  • 96
    • 3142669010 scopus 로고    scopus 로고
    • SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes
    • Blache P., van de Wetering M., Duluc I., et al. SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes. J Cell Biol 2004, 166:37-47.
    • (2004) J Cell Biol , vol.166 , pp. 37-47
    • Blache, P.1    van de Wetering, M.2    Duluc, I.3
  • 97
    • 79958051227 scopus 로고    scopus 로고
    • Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice
    • Dorrell C., Erker L., Schug J., et al. Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice. Genes Dev 2011, 25:1193-1203.
    • (2011) Genes Dev , vol.25 , pp. 1193-1203
    • Dorrell, C.1    Erker, L.2    Schug, J.3
  • 98
    • 84055199890 scopus 로고    scopus 로고
    • Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration
    • Malato Y., Naqvi S., Schurmann N., et al. Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration. J Clin Invest 2011, 121:4850-4860.
    • (2011) J Clin Invest , vol.121 , pp. 4850-4860
    • Malato, Y.1    Naqvi, S.2    Schurmann, N.3
  • 99
  • 101
    • 71649092364 scopus 로고    scopus 로고
    • Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth
    • Solar M., Cardalda C., Houbracken I., et al. Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth. Dev Cell 2009, 17:849-860.
    • (2009) Dev Cell , vol.17 , pp. 849-860
    • Solar, M.1    Cardalda, C.2    Houbracken, I.3
  • 102
    • 70149123248 scopus 로고    scopus 로고
    • Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development
    • Mead T.J., Yutzey K.E. Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development. Proc Natl Acad Sci U S A 2009, 106:14420-14425.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 14420-14425
    • Mead, T.J.1    Yutzey, K.E.2
  • 103
    • 51849085670 scopus 로고    scopus 로고
    • Repression of chondrogenesis through binding of notch signaling proteins HES-1 and HEY-1 to N-box domains in the COL2A1 enhancer site
    • Grogan S.P., Olee T., Hiraoka K., Lotz M.K. Repression of chondrogenesis through binding of notch signaling proteins HES-1 and HEY-1 to N-box domains in the COL2A1 enhancer site. Arthritis Rheum 2008, 58:2754-2763.
    • (2008) Arthritis Rheum , vol.58 , pp. 2754-2763
    • Grogan, S.P.1    Olee, T.2    Hiraoka, K.3    Lotz, M.K.4
  • 104
    • 77951964203 scopus 로고    scopus 로고
    • Bone regeneration: the stem/progenitor cells point of view
    • Deschaseaux F., Pontikoglou C., Sensebe L. Bone regeneration: the stem/progenitor cells point of view. J Cell Mol Med 2010, 14:103-115.
    • (2010) J Cell Mol Med , vol.14 , pp. 103-115
    • Deschaseaux, F.1    Pontikoglou, C.2    Sensebe, L.3
  • 105
    • 84902130533 scopus 로고    scopus 로고
    • Downregulation of Sox9 expression associates with hepatogenic differentiation of human liver mesenchymal stem/progenitor cells
    • Paganelli M., Nyabi O., Sid B., et al. Downregulation of Sox9 expression associates with hepatogenic differentiation of human liver mesenchymal stem/progenitor cells. Stem Cells Dev 2014, 23:1377-1391.
    • (2014) Stem Cells Dev , vol.23 , pp. 1377-1391
    • Paganelli, M.1    Nyabi, O.2    Sid, B.3
  • 106
    • 44449083814 scopus 로고    scopus 로고
    • Regulation of Sox9 activity by crosstalk with nuclear factor-kappaB and retinoic acid receptors
    • Rockel J.S., Kudirka J.C., Guzi A.J., Bernier S.M. Regulation of Sox9 activity by crosstalk with nuclear factor-kappaB and retinoic acid receptors. Arthritis Res Ther 2008, 10:R3.
    • (2008) Arthritis Res Ther , vol.10 , pp. R3
    • Rockel, J.S.1    Kudirka, J.C.2    Guzi, A.J.3    Bernier, S.M.4
  • 107
    • 67650395590 scopus 로고    scopus 로고
    • Transcriptional induction of SOX9 by NF-kappaB family member RelA in chondrogenic cells
    • Ushita M., Saito T., Ikeda T., et al. Transcriptional induction of SOX9 by NF-kappaB family member RelA in chondrogenic cells. Osteoarthritis Cartilage 2009, 17:1065-1075.
    • (2009) Osteoarthritis Cartilage , vol.17 , pp. 1065-1075
    • Ushita, M.1    Saito, T.2    Ikeda, T.3
  • 108
    • 84883410708 scopus 로고    scopus 로고
    • Epigenetic regulation of SOX9 by the NF-kappaB signaling pathway in pancreatic cancer stem cells
    • Sun L., Mathews L.A., Cabarcas S.M., et al. Epigenetic regulation of SOX9 by the NF-kappaB signaling pathway in pancreatic cancer stem cells. Stem Cells 2013, 31:1454-1466.
    • (2013) Stem Cells , vol.31 , pp. 1454-1466
    • Sun, L.1    Mathews, L.A.2    Cabarcas, S.M.3
  • 109
    • 49649109581 scopus 로고    scopus 로고
    • Sox9, a key transcription factor of bone morphogenetic protein-2-induced chondrogenesis, is activated through BMP pathway and a CCAAT box in the proximal promoter
    • Pan Q., Yu Y., Chen Q., et al. Sox9, a key transcription factor of bone morphogenetic protein-2-induced chondrogenesis, is activated through BMP pathway and a CCAAT box in the proximal promoter. J Cell Physiol 2008, 217:228-241.
    • (2008) J Cell Physiol , vol.217 , pp. 228-241
    • Pan, Q.1    Yu, Y.2    Chen, Q.3
  • 110
    • 34247376587 scopus 로고    scopus 로고
    • BMP and FGF regulatory pathways in semilunar valve precursor cells
    • Zhao B., Etter L., Hinton R.B., Benson D.W. BMP and FGF regulatory pathways in semilunar valve precursor cells. Dev Dyn 2007, 236:971-980.
    • (2007) Dev Dyn , vol.236 , pp. 971-980
    • Zhao, B.1    Etter, L.2    Hinton, R.B.3    Benson, D.W.4
  • 111
    • 80755187146 scopus 로고    scopus 로고
    • Activin, BMP and FGF pathways cooperate to promote endoderm and pancreatic lineage cell differentiation from human embryonic stem cells
    • Xu X., Browning V.L., Odorico J.S. Activin, BMP and FGF pathways cooperate to promote endoderm and pancreatic lineage cell differentiation from human embryonic stem cells. Mech Dev 2011, 128:412-427.
    • (2011) Mech Dev , vol.128 , pp. 412-427
    • Xu, X.1    Browning, V.L.2    Odorico, J.S.3
  • 112
    • 33644865499 scopus 로고    scopus 로고
    • FGF9 can induce endochondral ossification in cranial mesenchyme
    • Govindarajan V., Overbeek P.A. FGF9 can induce endochondral ossification in cranial mesenchyme. BMC Dev Biol 2006, 6:7.
    • (2006) BMC Dev Biol , vol.6 , pp. 7
    • Govindarajan, V.1    Overbeek, P.A.2
  • 113
    • 84903132652 scopus 로고    scopus 로고
    • FGF signaling activates a Sox9-Sox10 pathway for the formation and branching morphogenesis of mouse ocular glands
    • Chen Z., Huang J., Liu Y., et al. FGF signaling activates a Sox9-Sox10 pathway for the formation and branching morphogenesis of mouse ocular glands. Development 2014, 141:2691-2701.
    • (2014) Development , vol.141 , pp. 2691-2701
    • Chen, Z.1    Huang, J.2    Liu, Y.3
  • 114
    • 84865277434 scopus 로고    scopus 로고
    • A Sox9/Fgf feed-forward loop maintains pancreatic organ identity
    • Seymour P.A., Shih H.P., Patel N.A., et al. A Sox9/Fgf feed-forward loop maintains pancreatic organ identity. Development 2012, 139:3363-3372.
    • (2012) Development , vol.139 , pp. 3363-3372
    • Seymour, P.A.1    Shih, H.P.2    Patel, N.A.3
  • 115
    • 34147190365 scopus 로고    scopus 로고
    • Preexisting pancreatic acinar cells contribute to acinar cell, but not islet beta cell, regeneration
    • Desai B.M., Oliver-Krasinski J., De Leon D.D., et al. Preexisting pancreatic acinar cells contribute to acinar cell, but not islet beta cell, regeneration. J Clin Invest 2007, 117:971-977.
    • (2007) J Clin Invest , vol.117 , pp. 971-977
    • Desai, B.M.1    Oliver-Krasinski, J.2    De Leon, D.D.3
  • 116
    • 2342510386 scopus 로고    scopus 로고
    • Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation
    • Dor Y., Brown J., Martinez O.I., Melton D.A. Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature 2004, 429:41-46.
    • (2004) Nature , vol.429 , pp. 41-46
    • Dor, Y.1    Brown, J.2    Martinez, O.I.3    Melton, D.A.4
  • 117
    • 0020615253 scopus 로고
    • The campomelic syndrome: review, report of 17 cases, and follow-up on the currently 17-year-old boy first reported by Maroteaux, etal in 1971
    • Houston C.S., Opitz J.M., Spranger J.W., et al. The campomelic syndrome: review, report of 17 cases, and follow-up on the currently 17-year-old boy first reported by Maroteaux, etal in 1971. Am J Med Genet 1983, 15:3-28.
    • (1983) Am J Med Genet , vol.15 , pp. 3-28
    • Houston, C.S.1    Opitz, J.M.2    Spranger, J.W.3
  • 120
    • 84870716063 scopus 로고    scopus 로고
    • Trps1 and its target gene Sox9 regulate epithelial proliferation in the developing hair follicle and are associated with hypertrichosis
    • Fantauzzo K.A., Kurban M., Levy B., Christiano A.M. Trps1 and its target gene Sox9 regulate epithelial proliferation in the developing hair follicle and are associated with hypertrichosis. PLoS Genet 2012, 8:e1003002.
    • (2012) PLoS Genet , vol.8 , pp. e1003002
    • Fantauzzo, K.A.1    Kurban, M.2    Levy, B.3    Christiano, A.M.4
  • 122
    • 84877117939 scopus 로고    scopus 로고
    • Underlying potential: cellular and molecular determinants of adult liver repair
    • Diehl A.M., Chute J. Underlying potential: cellular and molecular determinants of adult liver repair. J Clin Invest 2013, 123:1858-1860.
    • (2013) J Clin Invest , vol.123 , pp. 1858-1860
    • Diehl, A.M.1    Chute, J.2
  • 123
    • 44649166478 scopus 로고    scopus 로고
    • Ectopic SOX9 mediates extracellular matrix deposition characteristic of organ fibrosis
    • Hanley K.P., Oakley F., Sugden S., Wilson D.I., Mann D.A., Hanley N.A. Ectopic SOX9 mediates extracellular matrix deposition characteristic of organ fibrosis. J Biol Chem 2008, 283:14063-14071.
    • (2008) J Biol Chem , vol.283 , pp. 14063-14071
    • Hanley, K.P.1    Oakley, F.2    Sugden, S.3    Wilson, D.I.4    Mann, D.A.5    Hanley, N.A.6
  • 124
    • 34548435968 scopus 로고    scopus 로고
    • Laser capture microdissection-microarray analysis of focal segmental glomerulosclerosis glomeruli
    • Bennett M.R., Czech K.A., Arend L.J., Witte D.P., Devarajan P., Potter S.S. Laser capture microdissection-microarray analysis of focal segmental glomerulosclerosis glomeruli. Nephron Exp Nephrol 2007, 107:e30-e40.
    • (2007) Nephron Exp Nephrol , vol.107 , pp. e30-e40
    • Bennett, M.R.1    Czech, K.A.2    Arend, L.J.3    Witte, D.P.4    Devarajan, P.5    Potter, S.S.6
  • 125
    • 34447306330 scopus 로고    scopus 로고
    • SRY-related HMG box 9 regulates the expression of Col4a2 through transactivating its enhancer element in mesangial cells
    • Sumi E., Iehara N., Akiyama H., et al. SRY-related HMG box 9 regulates the expression of Col4a2 through transactivating its enhancer element in mesangial cells. Am J Pathol 2007, 170:1854-1864.
    • (2007) Am J Pathol , vol.170 , pp. 1854-1864
    • Sumi, E.1    Iehara, N.2    Akiyama, H.3
  • 126
    • 84871336830 scopus 로고    scopus 로고
    • Sox9 drives columnar differentiation of esophageal squamous epithelium: a possible role in the pathogenesis of Barrett's esophagus
    • Clemons N.J., Wang D.H., Croagh D., et al. Sox9 drives columnar differentiation of esophageal squamous epithelium: a possible role in the pathogenesis of Barrett's esophagus. Am J Physiol Gastrointest Liver Physiol 2012, 303:G1335-G1346.
    • (2012) Am J Physiol Gastrointest Liver Physiol , vol.303 , pp. G1335-G1346
    • Clemons, N.J.1    Wang, D.H.2    Croagh, D.3
  • 127
    • 3042670072 scopus 로고    scopus 로고
    • Suppression of growth and tumorigenicity in the prostate tumor cell line M12 by overexpression of the transcription factor SOX9
    • Drivdahl R., Haugk K.H., Sprenger C.C., Nelson P.S., Tennant M.K., Plymate S.R. Suppression of growth and tumorigenicity in the prostate tumor cell line M12 by overexpression of the transcription factor SOX9. Oncogene 2004, 23:4584-4593.
    • (2004) Oncogene , vol.23 , pp. 4584-4593
    • Drivdahl, R.1    Haugk, K.H.2    Sprenger, C.C.3    Nelson, P.S.4    Tennant, M.K.5    Plymate, S.R.6
  • 128
    • 1642312538 scopus 로고    scopus 로고
    • Expression of a transcription factor, SOX9, in Sertoli-stromal cell tumors of the ovary
    • Kato N., Fukase M., Motoyama T. Expression of a transcription factor, SOX9, in Sertoli-stromal cell tumors of the ovary. Int J Gynecol Pathol 2004, 23:180-181.
    • (2004) Int J Gynecol Pathol , vol.23 , pp. 180-181
    • Kato, N.1    Fukase, M.2    Motoyama, T.3
  • 129
    • 75449103584 scopus 로고    scopus 로고
    • Integrative genomic analyses of neurofibromatosis tumours identify SOX9 as a biomarker and survival gene
    • Miller S.J., Jessen W.J., Mehta T., et al. Integrative genomic analyses of neurofibromatosis tumours identify SOX9 as a biomarker and survival gene. EMBO Mol Med 2009, 1:236-248.
    • (2009) EMBO Mol Med , vol.1 , pp. 236-248
    • Miller, S.J.1    Jessen, W.J.2    Mehta, T.3
  • 130
    • 65249112671 scopus 로고    scopus 로고
    • Upregulation of SOX9 inhibits the growth of human and mouse melanomas and restores their sensitivity to retinoic acid
    • Passeron T., Valencia J.C., Namiki T., et al. Upregulation of SOX9 inhibits the growth of human and mouse melanomas and restores their sensitivity to retinoic acid. J Clin Invest 2009, 119:954-963.
    • (2009) J Clin Invest , vol.119 , pp. 954-963
    • Passeron, T.1    Valencia, J.C.2    Namiki, T.3
  • 131
    • 84884807940 scopus 로고    scopus 로고
    • SOX9 is highly expressed in nonampullary duodenal adenoma and adenocarcinoma in humans
    • Sakamoto H., Mutoh H., Miura Y., Sashikawa M., Yamamoto H., Sugano K. SOX9 is highly expressed in nonampullary duodenal adenoma and adenocarcinoma in humans. Gut Liver 2013, 7:513-518.
    • (2013) Gut Liver , vol.7 , pp. 513-518
    • Sakamoto, H.1    Mutoh, H.2    Miura, Y.3    Sashikawa, M.4    Yamamoto, H.5    Sugano, K.6
  • 132
    • 69849089410 scopus 로고    scopus 로고
    • Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines
    • Swartling F.J., Ferletta M., Kastemar M., Weiss W.A., Westermark B. Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines. Oncogene 2009, 28:3121-3131.
    • (2009) Oncogene , vol.28 , pp. 3121-3131
    • Swartling, F.J.1    Ferletta, M.2    Kastemar, M.3    Weiss, W.A.4    Westermark, B.5
  • 133
    • 40549128662 scopus 로고    scopus 로고
    • SOX9 expression is a general marker of basal cell carcinoma and adnexal-related neoplasms
    • Vidal V.P., Ortonne N., Schedl A. SOX9 expression is a general marker of basal cell carcinoma and adnexal-related neoplasms. J Cutan Pathol 2008, 35:373-379.
    • (2008) J Cutan Pathol , vol.35 , pp. 373-379
    • Vidal, V.P.1    Ortonne, N.2    Schedl, A.3
  • 134
    • 40949145618 scopus 로고    scopus 로고
    • SOX9 is expressed in human fetal prostate epithelium and enhances prostate cancer invasion
    • Wang H., Leav I., Ibaragi S., et al. SOX9 is expressed in human fetal prostate epithelium and enhances prostate cancer invasion. Cancer Res 2008, 68:1625-1630.
    • (2008) Cancer Res , vol.68 , pp. 1625-1630
    • Wang, H.1    Leav, I.2    Ibaragi, S.3
  • 135
    • 33846673020 scopus 로고    scopus 로고
    • SOX9 is expressed in normal prostate basal cells and regulates androgen receptor expression in prostate cancer cells
    • Wang H., McKnight N.C., Zhang T., Lu M.L., Balk S.P., Yuan X. SOX9 is expressed in normal prostate basal cells and regulates androgen receptor expression in prostate cancer cells. Cancer Res 2007, 67:528-536.
    • (2007) Cancer Res , vol.67 , pp. 528-536
    • Wang, H.1    McKnight, N.C.2    Zhang, T.3    Lu, M.L.4    Balk, S.P.5    Yuan, X.6
  • 136
    • 76249098305 scopus 로고    scopus 로고
    • SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation
    • Thomsen M.K., Ambroisine L., Wynn S., et al. SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation. Cancer Res 2010, 70:979-987.
    • (2010) Cancer Res , vol.70 , pp. 979-987
    • Thomsen, M.K.1    Ambroisine, L.2    Wynn, S.3
  • 137
    • 57349137675 scopus 로고    scopus 로고
    • Androgen-induced programs for prostate epithelial growth and invasion arise in embryogenesis and are reactivated in cancer
    • Schaeffer E.M., Marchionni L., Huang Z., et al. Androgen-induced programs for prostate epithelial growth and invasion arise in embryogenesis and are reactivated in cancer. Oncogene 2008, 27:7180-7191.
    • (2008) Oncogene , vol.27 , pp. 7180-7191
    • Schaeffer, E.M.1    Marchionni, L.2    Huang, Z.3
  • 139
    • 84861867515 scopus 로고    scopus 로고
    • Translocation affecting sonic hedgehog genes in basal-cell carcinoma
    • Gomez-Ospina N., Chang A.L., Qu K., Oro A.E. Translocation affecting sonic hedgehog genes in basal-cell carcinoma. N. Engl J Med 2012, 366:2233-2234.
    • (2012) N. Engl J Med , vol.366 , pp. 2233-2234
    • Gomez-Ospina, N.1    Chang, A.L.2    Qu, K.3    Oro, A.E.4
  • 140
    • 84870803922 scopus 로고    scopus 로고
    • Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma
    • Kopp J.L., von Figura G., Mayes E., et al. Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma. Cancer Cell 2012, 22:737-750.
    • (2012) Cancer Cell , vol.22 , pp. 737-750
    • Kopp, J.L.1    von Figura, G.2    Mayes, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.