메뉴 건너뛰기




Volumn 110, Issue 45, 2013, Pages 18042-18051

Lung epithelial branching program antagonizes alveolar differentiation

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR; K RAS PROTEIN; TRANSCRIPTION FACTOR SOX9;

EID: 84887308205     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1311760110     Document Type: Article
Times cited : (148)

References (53)
  • 1
    • 74049139927 scopus 로고    scopus 로고
    • Preparing for the first breath: Genetic and cellular mechanisms in lung development
    • Morrisey EE, Hogan BL (2010) Preparing for the first breath: Genetic and cellular mechanisms in lung development. Dev Cell 18(1):8-23.
    • (2010) Dev Cell , vol.18 , Issue.1 , pp. 8-23
    • Morrisey, E.E.1    Hogan, B.L.2
  • 2
    • 44849091512 scopus 로고    scopus 로고
    • The branching programme of mouse lung development
    • Metzger RJ, Klein OD, Martin GR, Krasnow MA (2008) The branching programme of mouse lung development. Nature 453(7196):745-750.
    • (2008) Nature , vol.453 , Issue.7196 , pp. 745-750
    • Metzger, R.J.1    Klein, O.D.2    Martin, G.R.3    Krasnow, M.A.4
  • 3
    • 0033961133 scopus 로고    scopus 로고
    • An important role for the iiib isoform of fibroblast growth factor receptor 2 (fgfr2) in mesenchymal-epithelial signalling during mouse organogenesis
    • De Moerlooze L, et al. (2000) An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis. Development 127(3):483-492.
    • (2000) Development , vol.127 , Issue.3 , pp. 483-492
    • De Moerlooze, L.1
  • 4
    • 0032947346 scopus 로고    scopus 로고
    • Fgf10 is essential for limb and lung formation
    • Sekine K, et al. (1999) Fgf10 is essential for limb and lung formation. Nat Genet 21(1): 138-141.
    • (1999) Nat Genet , vol.21 , Issue.1 , pp. 138-141
    • Sekine, K.1
  • 5
    • 79960487665 scopus 로고    scopus 로고
    • Control of mitotic spindle angle by the ras-regulated erk1/2 pathway determines lung tube shape
    • Tang N, Marshall WF, McMahon M, Metzger RJ, Martin GR (2011) Control of mitotic spindle angle by the RAS-regulated ERK1/2 pathway determines lung tube shape. Science 333(6040):342-345.
    • (2011) Science , vol.333 , Issue.6040 , pp. 342-345
    • Tang, N.1    Marshall, W.F.2    McMahon, M.3    Metzger, R.J.4    Martin, G.R.5
  • 6
    • 33744524149 scopus 로고    scopus 로고
    • Regulation of early lung morphogenesis: Questions, facts and controversies
    • Cardoso WV, Lü J (2006) Regulation of early lung morphogenesis: Questions, facts and controversies. Development 133(9):1611-1624.
    • (2006) Development , vol.133 , Issue.9 , pp. 1611-1624
    • Cardoso, W.V.1    Lü, J.2
  • 7
    • 0021675427 scopus 로고
    • Alveolar type i and type ii cells
    • Ward HE, Nicholas TE (1984) Alveolar type I and type II cells. Aust N Z J Med 14(5, Suppl 3):731-734.
    • (1984) Aust N Z J Med , vol.14 , Issue.5 SUPPL. 3 , pp. 731-734
    • Ward, H.E.1    Nicholas, T.E.2
  • 8
    • 33645729295 scopus 로고    scopus 로고
    • C/ebpalpha is required for lung maturation at birth
    • Martis PC, et al. (2006) C/EBPalpha is required for lung maturation at birth. Development 133(6):1155-1164.
    • (2006) Development , vol.133 , Issue.6 , pp. 1155-1164
    • Martis, P.C.1
  • 9
    • 79952394870 scopus 로고    scopus 로고
    • Camp response element binding protein is required for differentiation of respiratory epithelium during murine development
    • Bird AD, et al. (2011) cAMP response element binding protein is required for differentiation of respiratory epithelium during murine development. PLoS ONE 6(3): e17843.
    • (2011) PLoS ONE , vol.6 , Issue.3
    • Bird, A.D.1
  • 10
    • 77953318366 scopus 로고    scopus 로고
    • Carm1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells
    • O'Brien KB, et al. (2010) CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells. Development 137(13):2147-2156.
    • (2010) Development , vol.137 , Issue.13 , pp. 2147-2156
    • O'Brien, K.B.1
  • 11
    • 78149287302 scopus 로고    scopus 로고
    • Reduced viability of mice with lung epithelial-specific knockout of glucocorticoid receptor
    • Manwani N, et al. (2010) Reduced viability of mice with lung epithelial-specific knockout of glucocorticoid receptor. Am J Respir Cell Mol Biol 43(5):599-606.
    • (2010) Am J Respir Cell Mol Biol , vol.43 , Issue.5 , pp. 599-606
    • Manwani, N.1
  • 12
    • 79961005597 scopus 로고    scopus 로고
    • Glucocorticoid activity during lung maturation is essential in mesenchymal and less in alveolar epithelial cells
    • Habermehl D, et al. (2011) Glucocorticoid activity during lung maturation is essential in mesenchymal and less in alveolar epithelial cells. Mol Endocrinol 25(8): 1280-1288.
    • (2011) Mol Endocrinol , vol.25 , Issue.8 , pp. 1280-1288
    • Habermehl, D.1
  • 13
    • 84877001185 scopus 로고    scopus 로고
    • Dlg5 maintains apical apkc and regulates progenitor differentiation during lung morphogenesis
    • Nechiporuk T, Klezovitch O, Nguyen L, Vasioukhin V (2013) Dlg5 maintains apical aPKC and regulates progenitor differentiation during lung morphogenesis. Dev Biol 377(2):375-384.
    • (2013) Dev Biol , vol.377 , Issue.2 , pp. 375-384
    • Nechiporuk, T.1    Klezovitch, O.2    Nguyen, L.3    Vasioukhin, V.4
  • 14
    • 78651254737 scopus 로고    scopus 로고
    • Eyes absent 1 (eya1) is a critical coordinator of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung
    • El-Hashash AH, Al Alam D, Turcatel G, Bellusci S, Warburton D (2011) Eyes absent 1 (Eya1) is a critical coordinator of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung. Dev Biol 350(1):112-126.
    • (2011) Dev Biol , vol.350 , Issue.1 , pp. 112-126
    • El-Hashash, A.H.1    Al Alam, D.2    Turcatel, G.3    Bellusci, S.4    Warburton, D.5
  • 15
    • 20444445954 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling acts upstream of n-myc, bmp4, and fgf signaling to regulate proximal-distal patterning in the lung
    • Shu W, et al. (2005) Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung. Dev Biol 283(1): 226-239.
    • (2005) Dev Biol , vol.283 , Issue.1 , pp. 226-239
    • Shu, W.1
  • 17
    • 84871400064 scopus 로고    scopus 로고
    • Integrin beta 1 suppresses multilayering of a simple epithelium
    • Chen J, Krasnow MA (2012) Integrin Beta 1 suppresses multilayering of a simple epithelium. PLoS ONE 7(12):e52886.
    • (2012) PLoS ONE , vol.7 , Issue.12
    • Chen, J.1    Krasnow, M.A.2
  • 18
    • 73949140059 scopus 로고    scopus 로고
    • A robust and high-throughput cre reporting and characterization system for the whole mouse brain
    • Madisen L, et al. (2010) A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. Nat Neurosci 13(1):133-140.
    • (2010) Nat Neurosci , vol.13 , Issue.1 , pp. 133-140
    • Madisen, L.1
  • 19
    • 69549090537 scopus 로고    scopus 로고
    • Multiple roles for sox2 in the developing and adult mouse trachea
    • Que J, Luo X, Schwartz RJ, Hogan BL (2009) Multiple roles for Sox2 in the developing and adult mouse trachea. Development 136(11):1899-1907.
    • (2009) Development , vol.136 , Issue.11 , pp. 1899-1907
    • Que, J.1    Luo, X.2    Schwartz, R.J.3    Hogan, B.L.4
  • 20
    • 80053914464 scopus 로고    scopus 로고
    • Sox2(+) adult stem and progenitor cells are important for tissue regeneration and survival of mice
    • Arnold K, et al. (2011) Sox2(+) adult stem and progenitor cells are important for tissue regeneration and survival of mice. Cell Stem Cell 9(4):317-329.
    • (2011) Cell Stem Cell , vol.9 , Issue.4 , pp. 317-329
    • Arnold, K.1
  • 21
    • 13944260928 scopus 로고    scopus 로고
    • Normal lung development and function after sox9 inactivation in the respiratory epithelium
    • Perl AK, Kist R, Shan Z, Scherer G, Whitsett JA (2005) Normal lung development and function after Sox9 inactivation in the respiratory epithelium. Genesis 41(1):23-32.
    • (2005) Genesis , vol.41 , Issue.1 , pp. 23-32
    • Perl, A.K.1    Kist, R.2    Shan, Z.3    Scherer, G.4    Whitsett, J.A.5
  • 22
    • 0027293170 scopus 로고
    • Murine clusterin: Molecular cloning and mrna localization of a gene associated with epithelial differentiation processes during embryogenesis
    • French LE, et al. (1993) Murine clusterin: Molecular cloning and mRNA localization of a gene associated with epithelial differentiation processes during embryogenesis. J Cell Biol 122(5):1119-1130.
    • (1993) J Cell Biol , vol.122 , Issue.5 , pp. 1119-1130
    • French, L.E.1
  • 23
    • 46049093965 scopus 로고    scopus 로고
    • Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme
    • Rajagopal J, et al. (2008) Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme. Development 135(9): 1625-1634.
    • (2008) Development , vol.135 , Issue.9 , pp. 1625-1634
    • Rajagopal, J.1
  • 24
    • 0036955802 scopus 로고    scopus 로고
    • Differential gene expression in the distal tip endoderm of the embryonic mouse lung
    • Liu Y, Hogan BL (2002) Differential gene expression in the distal tip endoderm of the embryonic mouse lung. Gene Expr Patterns 2(3-4):229-233.
    • (2002) Gene Expr Patterns , vol.2 , Issue.3-4 , pp. 229-233
    • Liu, Y.1    Hogan, B.L.2
  • 25
    • 41149121471 scopus 로고    scopus 로고
    • Misexpression of mia disrupts lung morphogenesis and causes neonatal death
    • Lin S, et al. (2008) Misexpression of MIA disrupts lung morphogenesis and causes neonatal death. Dev Biol 316(2):441-455.
    • (2008) Dev Biol , vol.316 , Issue.2 , pp. 441-455
    • Lin, S.1
  • 26
    • 0037134008 scopus 로고    scopus 로고
    • Optical projection tomography as a tool for 3d microscopy and gene expression studies
    • Sharpe J, et al. (2002) Optical projection tomography as a tool for 3D microscopy and gene expression studies. Science 296(5567):541-545.
    • (2002) Science , vol.296 , Issue.5567 , pp. 541-545
    • Sharpe, J.1
  • 27
    • 0034705991 scopus 로고    scopus 로고
    • Developmental expression of the xenopus nkx2-1 and nkx2-4 genes
    • Small EM, Vokes SA, Garriock RJ, Li D, Krieg PA (2000) Developmental expression of the Xenopus Nkx2-1 and Nkx2-4 genes. Mech Dev 96(2):259-262.
    • (2000) Mech Dev , vol.96 , Issue.2 , pp. 259-262
    • Small, E.M.1    Vokes, S.A.2    Garriock, R.J.3    Li, D.4    Krieg, P.A.5
  • 28
    • 33750803450 scopus 로고    scopus 로고
    • Lung specific developmental expression of the xenopus laevis surfactant protein c and b genes
    • Hyatt BA, Resnik ER, Johnson NS, Lohr JL, Cornfield DN (2007) Lung specific developmental expression of the Xenopus laevis surfactant protein C and B genes. Gene Expr Patterns 7(1-2):8-14.
    • (2007) Gene Expr Patterns , vol.7 , Issue.1-2 , pp. 8-14
    • Hyatt, B.A.1    Resnik, E.R.2    Johnson, N.S.3    Lohr, J.L.4    Cornfield, D.N.5
  • 29
    • 0035893252 scopus 로고    scopus 로고
    • Analysis of lung tumor initiation and progression using conditional expression of oncogenic k-ras
    • Jackson EL, et al. (2001) Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras. Genes Dev 15(24):3243-3248.
    • (2001) Genes Dev , vol.15 , Issue.24 , pp. 3243-3248
    • Jackson, E.L.1
  • 30
    • 78649700651 scopus 로고    scopus 로고
    • Sox9-expressing precursors are the cellular origin of the cruciate ligament of the knee joint and the limb tendons
    • Soeda T, et al. (2010) Sox9-expressing precursors are the cellular origin of the cruciate ligament of the knee joint and the limb tendons. Genesis 48(11):635-644.
    • (2010) Genesis , vol.48 , Issue.11 , pp. 635-644
    • Soeda, T.1
  • 31
    • 35548932872 scopus 로고    scopus 로고
    • A global double-fluorescent cre reporter mouse
    • Muzumdar MD, Tasic B, Miyamichi K, Li L, Luo L (2007) A global double-fluorescent Cre reporter mouse. Genesis 45(9):593-605.
    • (2007) Genesis , vol.45 , Issue.9 , pp. 593-605
    • Muzumdar, M.D.1    Tasic, B.2    Miyamichi, K.3    Li, L.4    Luo, L.5
  • 32
    • 28844481452 scopus 로고    scopus 로고
    • The kras oncogene: Past, present, and future
    • Kranenburg O (2005) The KRAS oncogene: Past, present, and future. Biochim Biophys Acta 1756(2):81-82.
    • (2005) Biochim Biophys Acta , vol.1756 , Issue.2 , pp. 81-82
    • Kranenburg, O.1
  • 33
    • 0345135149 scopus 로고    scopus 로고
    • K-ras is an essential gene in the mouse with partial functional overlap with n-ras
    • Johnson L, et al. (1997) K-ras is an essential gene in the mouse with partial functional overlap with N-ras. Genes Dev 11(19):2468-2481.
    • (1997) Genes Dev , vol.11 , Issue.19 , pp. 2468-2481
    • Johnson, L.1
  • 34
    • 79952027353 scopus 로고    scopus 로고
    • Sox9 controls epithelial branching by activating ret effector genes during kidney development
    • Reginensi A, et al. (2011) SOX9 controls epithelial branching by activating RET effector genes during kidney development. Hum Mol Genet 20(6):1143-1153.
    • (2011) Hum Mol Genet , vol.20 , Issue.6 , pp. 1143-1153
    • Reginensi, A.1
  • 35
    • 84865277434 scopus 로고    scopus 로고
    • A sox9/fgf feed-forward loop maintains pancreatic organ identity
    • Seymour PA, et al. (2012) A Sox9/Fgf feed-forward loop maintains pancreatic organ identity. Development 139(18):3363-3372.
    • (2012) Development , vol.139 , Issue.18 , pp. 3363-3372
    • Seymour, P.A.1
  • 37
    • 80053128156 scopus 로고    scopus 로고
    • A resource of cre driver lines for genetic targeting of gabaergic neurons in cerebral cortex
    • Taniguchi H, et al. (2011) A resource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex. Neuron 71(6):995-1013.
    • (2011) Neuron , vol.71 , Issue.6 , pp. 995-1013
    • Taniguchi, H.1
  • 38
    • 0033564697 scopus 로고    scopus 로고
    • Cdk inhibitors: Positive and negative regulators of g1- phase progression
    • Sherr CJ, Roberts JM (1999) CDK inhibitors: Positive and negative regulators of G1- phase progression. Genes Dev 13(12):1501-1512.
    • (1999) Genes Dev , vol.13 , Issue.12 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 39
    • 77949531110 scopus 로고    scopus 로고
    • Sox2 is required for maintenance and differentiation of bronchiolar clara, ciliated, and goblet cells
    • Tompkins DH, et al. (2009) Sox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cells. PLoS ONE 4(12):e8248.
    • (2009) PLoS ONE , vol.4 , Issue.12
    • Tompkins, D.H.1
  • 40
    • 0028557475 scopus 로고
    • Induction of alveolar type ii cell differentiation in fetal tracheal epithelium by grafted distal lung mesenchyme
    • Shannon JM (1994) Induction of alveolar type II cell differentiation in fetal tracheal epithelium by grafted distal lung mesenchyme. Dev Biol 166(2):600-614.
    • (1994) Dev Biol , vol.166 , Issue.2 , pp. 600-614
    • Shannon, J.M.1
  • 41
    • 10744222899 scopus 로고    scopus 로고
    • Cd208/dendritic cell-lysosomal associated membrane protein is a marker of normal and transformed type ii pneumocytes
    • Salaun B, et al. (2004) CD208/dendritic cell-lysosomal associated membrane protein is a marker of normal and transformed type II pneumocytes. Am J Pathol 164(3):861-871.
    • (2004) Am J Pathol , vol.164 , Issue.3 , pp. 861-871
    • Salaun, B.1
  • 42
    • 1942533534 scopus 로고    scopus 로고
    • Processing of pulmonary surfactant protein b by napsin and cathepsin h
    • Ueno T, et al. (2004) Processing of pulmonary surfactant protein B by napsin and cathepsin H. J Biol Chem 279(16):16178-16184.
    • (2004) J Biol Chem , vol.279 , Issue.16 , pp. 16178-16184
    • Ueno, T.1
  • 43
    • 77951909085 scopus 로고    scopus 로고
    • Alveolar surfactant homeostasis and the pathogenesis of pulmonary disease
    • Whitsett JA, Wert SE, Weaver TE (2010) Alveolar surfactant homeostasis and the pathogenesis of pulmonary disease. Annu Rev Med 61:105-119.
    • (2010) Annu Rev Med , vol.61 , pp. 105-119
    • Whitsett, J.A.1    Wert, S.E.2    Weaver, T.E.3
  • 44
    • 23944523818 scopus 로고    scopus 로고
    • From the archives of the afip: Lung disease in premature neonates: Radiologic-pathologic correlation
    • Agrons GA, Courtney SE, Stocker JT, Markowitz RI (2005) From the archives of the AFIP: Lung disease in premature neonates: radiologic-pathologic correlation. Radiographics 25(4):1047-1073.
    • (2005) Radiographics , vol.25 , Issue.4 , pp. 1047-1073
    • Agrons, G.A.1    Courtney, S.E.2    Stocker, J.T.3    Markowitz, R.I.4
  • 45
    • 77955358457 scopus 로고    scopus 로고
    • Lung organogenesis
    • Warburton D, et al. (2010) Lung organogenesis. Curr Top Dev Biol 90:73-158.
    • (2010) Curr Top Dev Biol , vol.90 , pp. 73-158
    • Warburton, D.1
  • 46
    • 38349104769 scopus 로고    scopus 로고
    • Beta-catenin is necessary to keep cells of ureteric bud/wolffian duct epithelium in a precursor state
    • Marose TD, Merkel CE, McMahon AP, Carroll TJ (2008) Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state. Dev Biol 314(1):112-126.
    • (2008) Dev Biol , vol.314 , Issue.1 , pp. 112-126
    • Marose, T.D.1    Merkel, C.E.2    McMahon, A.P.3    Carroll, T.J.4
  • 47
    • 42649134121 scopus 로고    scopus 로고
    • Canonical wnt/beta-catenin signaling is required for ureteric branching
    • Bridgewater D, et al. (2008) Canonical WNT/beta-catenin signaling is required for ureteric branching. Dev Biol 317(1):83-94.
    • (2008) Dev Biol , vol.317 , Issue.1 , pp. 83-94
    • Bridgewater, D.1
  • 48
    • 4644328190 scopus 로고    scopus 로고
    • Evidence for an expansion-based temporal shh gradient in specifying vertebrate digit identities
    • Harfe BD, et al. (2004) Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities. Cell 118(4):517-528.
    • (2004) Cell , vol.118 , Issue.4 , pp. 517-528
    • Harfe, B.D.1
  • 49
    • 0035810951 scopus 로고    scopus 로고
    • Haploinsufficiency of sox9 results in defective cartilage primordia and premature skeletal mineralization
    • Bi W, et al. (2001) Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization. Proc Natl Acad Sci USA 98(12):6698-6703.
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.12 , pp. 6698-6703
    • Bi, W.1
  • 50
    • 0038782306 scopus 로고    scopus 로고
    • Conditional inactivation of fgf receptor 2 reveals an essential role for fgf signaling in the regulation of osteoblast function and bone growth
    • Yu K, et al. (2003) Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth. Development 130(13):3063-3074.
    • (2003) Development , vol.130 , Issue.13 , pp. 3063-3074
    • Yu, K.1
  • 52
    • 60049099132 scopus 로고    scopus 로고
    • Requirement of wnt/beta-catenin signaling in pronephric kidney development
    • Lyons JP, et al. (2009) Requirement of Wnt/beta-catenin signaling in pronephric kidney development. Mech Dev 126(3-4):142-159.
    • (2009) Mech Dev , vol.126 , Issue.3-4 , pp. 142-159
    • Lyons, J.P.1
  • 53
    • 34548183083 scopus 로고    scopus 로고
    • Estrogen-related receptor beta/nr3b2 controls epithelial cell fate and endolymph production by the stria vascularis
    • Chen J, Nathans J (2007) Estrogen-related receptor beta/NR3B2 controls epithelial cell fate and endolymph production by the stria vascularis. Dev Cell 13(3):325-337.
    • (2007) Dev Cell , vol.13 , Issue.3 , pp. 325-337
    • Chen, J.1    Nathans, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.