-
1
-
-
21344462346
-
Five-year follow-up after clinical islet transplantation
-
Ryan EA, BW Paty, PA Senior, D Bigam, E Alfadhli, NM Kneteman, JRT Lakey and AMJ Shapiro (2005). Five-year follow-up after clinical islet transplantation. Diabetes 54:2060-2069.
-
(2005)
Diabetes
, vol.54
, pp. 2060-2069
-
-
Ryan, E.A.1
Paty, B.W.2
Senior, P.A.3
Bigam, D.4
Alfadhli, E.5
Kneteman, N.M.6
Lakey, J.R.T.7
Shapiro, A.M.J.8
-
2
-
-
0034721255
-
Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen
-
Shapiro AM, JR Lakey, EA Ryan, GS Korbutt, E Toth, GL Warnock, NM Kneteman and RV Rajotte (2000). Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 343:230-238.
-
(2000)
N Engl J Med
, vol.343
, pp. 230-238
-
-
Shapiro, A.M.1
Lakey, J.R.2
Ryan, E.A.3
Korbutt, G.S.4
Toth, E.5
Warnock, G.L.6
Kneteman, N.M.7
Rajotte, R.V.8
-
3
-
-
33846910410
-
SOX9 is required for maintenance of the pancreatic progenitor cell pool
-
Seymour PA, KK Freude, MN Tran, EE Mayes, J Jensen, R Kist, G Scherer and M Sander. (2007). SOX9 is required for maintenance of the pancreatic progenitor cell pool. Proc Natl Acad Sci U S A 104:1865-1870.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 1865-1870
-
-
Seymour, P.A.1
Freude, K.K.2
Tran, M.N.3
Mayes, E.E.4
Jensen, J.5
Kist, R.6
Scherer, G.7
Sander, M.8
-
4
-
-
53649102798
-
A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation
-
Seymour PA, KK Freude, CL Dubois, HP Shih, NA Patel and M Sander. (2008). A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation. Dev Biol 323:19-30.
-
(2008)
Dev Biol
, vol.323
, pp. 19-30
-
-
Seymour, P.A.1
Freude, K.K.2
Dubois, C.L.3
Shih, H.P.4
Patel, N.A.5
Sander, M.6
-
5
-
-
34547956892
-
Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium
-
Bastide P, C Darido, J Pannequin, R Kist, S Robine, C Marty-Double, F Bibeau, G Scherer, D Joubert, et al. (2007). Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium. J Cell Biol 178:635-648.
-
(2007)
J Cell Biol
, vol.178
, pp. 635-648
-
-
Bastide, P.1
Darido, C.2
Pannequin, J.3
Kist, R.4
Robine, S.5
Marty-Double, C.6
Bibeau, F.7
Scherer, G.8
Joubert, D.9
-
6
-
-
66149126941
-
Distinct SOX9 levels differentially mark stem/progenitor populations and enteroendocrine cells of the small intestine epithelium
-
Formeister EJ, AL Sionas, DK Lorance, CL Barkley, GH Lee and ST Magness. (2009). Distinct SOX9 levels differentially mark stem/progenitor populations and enteroendocrine cells of the small intestine epithelium. Am J Physiol Gastrointest Liver Physiol 296:G1108-G1118.
-
(2009)
Am J Physiol Gastrointest Liver Physiol
, vol.296
-
-
Formeister, E.J.1
Sionas, A.L.2
Lorance, D.K.3
Barkley, C.L.4
Lee, G.H.5
Magness, S.T.6
-
7
-
-
34547525676
-
Sox9 coordinates a transcriptional network in pancreatic progenitor cells
-
Lynn FC, SB Smith, ME Wilson, KY Yang, N Nekrep and MS German. (2007). Sox9 coordinates a transcriptional network in pancreatic progenitor cells. Proc Natl Acad Sci U S A 104:10500-10505.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 10500-10505
-
-
Lynn, F.C.1
Smith, S.B.2
Wilson, M.E.3
Yang, K.Y.4
Nekrep, N.5
German, M.S.6
-
8
-
-
0035106841
-
Floppy SOX: Mutual induced fit in hmg (high-mobility group) box-DNA recognition
-
Weiss MA. (2001). Floppy SOX: mutual induced fit in hmg (high-mobility group) box-DNA recognition. Mol Endocrinol 15:353-362.
-
(2001)
Mol Endocrinol
, vol.15
, pp. 353-362
-
-
Weiss, M.A.1
-
9
-
-
0033559518
-
From head to toes: The multiple facets of Sox proteins
-
Wegner M. (1999). From head to toes: the multiple facets of Sox proteins. Nucleic Acids Res 27:1409-1420.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 1409-1420
-
-
Wegner, M.1
-
10
-
-
0026696874
-
Sequence-specific interaction of the HMG box proteins TCF-1 and SRY occurs within the minor groove of a Watson-Crick double helix
-
van de Wetering M and H Clevers. (1992). Sequence-specific interaction of the HMG box proteins TCF-1 and SRY occurs within the minor groove of a Watson-Crick double helix. Embo J 11:3039-3044.
-
(1992)
Embo J
, vol.11
, pp. 3039-3044
-
-
Van De Wetering, M.1
Clevers, H.2
-
11
-
-
0027287821
-
Ancestry and diversity of the HMG box superfamily
-
Laudet V, D Stehelin and H Clevers. (1993). Ancestry and diversity of the HMG box superfamily. Nucleic Acids Res 21:2493-2501.
-
(1993)
Nucleic Acids Res
, vol.21
, pp. 2493-2501
-
-
Laudet, V.1
Stehelin, D.2
Clevers, H.3
-
12
-
-
0029739809
-
SOX genes: Architects of development
-
Prior HM and MA Walter. (1996). SOX genes: architects of development. Mol Med 2:405-412.
-
(1996)
Mol Med
, vol.2
, pp. 405-412
-
-
Prior, H.M.1
Walter, M.A.2
-
13
-
-
76749130545
-
Acquisition of SOX transcription factor specificity through protein-protein interaction, modulation of Wnt signalling and post-translational modification
-
Bernard P and VR Harley. (2010). Acquisition of SOX transcription factor specificity through protein-protein interaction, modulation of Wnt signalling and post-translational modification. Int J Biochem Cell Biol 42:400-410.
-
(2010)
Int J Biochem Cell Biol
, vol.42
, pp. 400-410
-
-
Bernard, P.1
Harley, V.R.2
-
14
-
-
79952455908
-
Understanding the role of SOX9 in acquired diseases: Lessons from development
-
Pritchett J, V Athwal, N Roberts, NA Hanley and KP Hanley. (2011). Understanding the role of SOX9 in acquired diseases: lessons from development. Trends Mol Med 17:166-174.
-
(2011)
Trends Mol Med
, vol.17
, pp. 166-174
-
-
Pritchett, J.1
Athwal, V.2
Roberts, N.3
Hanley, N.A.4
Hanley, K.P.5
-
15
-
-
76549093805
-
SOX-partner code for cell specification: Regulatory target selection and underlying molecular mechanisms
-
Kondoh H and Y Kamachi. (2010). SOX-partner code for cell specification: regulatory target selection and underlying molecular mechanisms. Int J Biochem Cell Biol 42:391-399.
-
(2010)
Int J Biochem Cell Biol
, vol.42
, pp. 391-399
-
-
Kondoh, H.1
Kamachi, Y.2
-
16
-
-
0034175998
-
Pairing SOX off: With partners in the regulation of embryonic development
-
Kamachi Y, M Uchikawa and H Kondoh. (2000). Pairing SOX off: with partners in the regulation of embryonic development. Trends Genet 16:182-187.
-
(2000)
Trends Genet
, vol.16
, pp. 182-187
-
-
Kamachi, Y.1
Uchikawa, M.2
Kondoh, H.3
-
17
-
-
0035996994
-
Novel SOX9 expression during human pancreas development correlates to abnormalities in Campomelic dysplasia
-
Piper K, SG Ball, JW Keeling, S Mansoor, DI Wilson and NA Hanley. (2002). Novel SOX9 expression during human pancreas development correlates to abnormalities in Campomelic dysplasia. Mech Dev 116:223-226.
-
(2002)
Mech Dev
, vol.116
, pp. 223-226
-
-
Piper, K.1
Ball, S.G.2
Keeling, J.W.3
Mansoor, S.4
Wilson, D.I.5
Hanley, N.A.6
-
18
-
-
0035810951
-
Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization
-
Bi W, W Huang, DJ Whitworth, JM Deng, Z Zhang, RR Behringer and B de Crombrugghe. (2001). Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization. Proc Natl Acad Sci U S A 98:6698-6703.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 6698-6703
-
-
Bi, W.1
Huang, W.2
Whitworth, D.J.3
Deng, J.M.4
Zhang, Z.5
Behringer, R.R.6
De Crombrugghe, B.7
-
19
-
-
70349705754
-
Long-range regulation at the SOX9 locus in development and disease
-
Gordon CT, TY Tan, S Benko, D Fitzpatrick, S Lyonnet and PG Farlie. (2009). Long-range regulation at the SOX9 locus in development and disease. J Med Genet 46:649-656.
-
(2009)
J Med Genet
, vol.46
, pp. 649-656
-
-
Gordon, C.T.1
Tan, T.Y.2
Benko, S.3
Fitzpatrick, D.4
Lyonnet, S.5
Farlie, P.G.6
-
20
-
-
0028135336
-
Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene
-
Foster JW, MA Dominguez-Steglich, S Guioli, C Kwok, PA Weller, M Stevanovic, J Weissenbach, S Mansour, ID Young and PN Goodfellow. (1994). Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene. Nature 372:525-530.
-
(1994)
Nature
, vol.372
, pp. 525-530
-
-
Foster, J.W.1
Dominguez-Steglich, M.A.2
Guioli, S.3
Kwok, C.4
Weller, P.A.5
Stevanovic, M.6
Weissenbach, J.7
Mansour, S.8
Young, I.D.9
Goodfellow, P.N.10
-
21
-
-
0028589588
-
Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9
-
Wagner T, J Wirth, J Meyer, B Zabel, M Held, J Zimmer, J Pasantes, FD Bricarelli, J Keutel, et al. (1994). Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9. Cell 79:1111-1120.
-
(1994)
Cell
, vol.79
, pp. 1111-1120
-
-
Wagner, T.1
Wirth, J.2
Meyer, J.3
Zabel, B.4
Held, M.5
Zimmer, J.6
Pasantes, J.7
Bricarelli, F.D.8
Keutel, J.9
-
22
-
-
34547549553
-
SOX9 is required for the differentiation of paneth cells in the intestinal epithelium
-
Mori-Akiyama Y, M van den Born, JH van Es, SR Hamilton, HP Adams, J Zhang, H Clevers and B de Crombrugghe. (2007). SOX9 is required for the differentiation of paneth cells in the intestinal epithelium. Gastroenterology 133:539-546.
-
(2007)
Gastroenterology
, vol.133
, pp. 539-546
-
-
Mori-Akiyama, Y.1
Born Van-Den, M.2
Van Es, J.H.3
Hamilton, S.R.4
Adams, H.P.5
Zhang, J.6
Clevers, H.7
De Crombrugghe, B.8
-
23
-
-
44649166478
-
Ectopic SOX9 mediates extracellular matrix deposition characteristic of organ fibrosis
-
Hanley KP, F Oakley, S Sugden, DI Wilson, DA Mann and NA Hanley. (2008). Ectopic SOX9 mediates extracellular matrix deposition characteristic of organ fibrosis. J Biol Chem 283:14063-14071.
-
(2008)
J Biol Chem
, vol.283
, pp. 14063-14071
-
-
Hanley, K.P.1
Oakley, F.2
Sugden, S.3
Wilson, D.I.4
Mann, D.A.5
Hanley, N.A.6
-
24
-
-
0031796252
-
Direct interaction of SRY-related protein SOX9 and steroidogenic factor 1 regulates transcription of the human anti-Müllerian hormone gene
-
de Santa Barbara P, N Bonneaud, B Boizet, M Desclozeaux, B Moniot, P Sudbeck, G Scherer, F Poulat and P Berta. (1998). Direct interaction of SRY-related protein SOX9 and steroidogenic factor 1 regulates transcription of the human anti-Müllerian hormone gene. Mol Cell Biol 18:6653-6665.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 6653-6665
-
-
De Santa Barbara, P.1
Bonneaud, N.2
Boizet, B.3
Desclozeaux, M.4
Moniot, B.5
Sudbeck, P.6
Scherer, G.7
Poulat, F.8
Berta, P.9
-
25
-
-
33644989691
-
Long-range upstream and downstream enhancers control distinct subsets of the complex spatiotemporal Sox9 expression pattern
-
Bagheri-Fam S, F Barrionuevo, U Dohrmann, T Günther, R Schüle, R Kemler, M Mallo, B Kanzler and G Scherer. (2006). Long-range upstream and downstream enhancers control distinct subsets of the complex spatiotemporal Sox9 expression pattern. Dev Biol 291:382-397.
-
(2006)
Dev Biol
, vol.291
, pp. 382-397
-
-
Bagheri-Fam, S.1
Barrionuevo, F.2
Dohrmann, U.3
Günther, T.4
Schüle, R.5
Kemler, R.6
Mallo, M.7
Kanzler, B.8
Scherer, G.9
-
26
-
-
84877252837
-
A far-upstream (- 70 kb) enhancer mediates Sox9 auto-regulation in somatic tissues during development and adult regeneration
-
Mead TJ, Q Wang, P Bhattaram, P Dy, S Afelik, J Jensen and V Lefebvre. (2013). A far-upstream (- 70 kb) enhancer mediates Sox9 auto-regulation in somatic tissues during development and adult regeneration. Nucleic Acids Res 41:4459-4469.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 4459-4469
-
-
Mead, T.J.1
Wang, Q.2
Bhattaram, P.3
Dy, P.4
Afelik, S.5
Jensen, J.6
Lefebvre, V.7
-
27
-
-
3142669010
-
SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes
-
Blache P, M van de Wetering, I Duluc, C Domon, P Berta, J-N Freund, H Clevers and P Jay. (2004). SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes. J Cell Biol 166:37-47.
-
(2004)
J Cell Biol
, vol.166
, pp. 37-47
-
-
Blache, P.1
Van De Wetering, M.2
Duluc, I.3
Domon, C.4
Berta, P.5
Freund, J.-N.6
Clevers, H.7
Jay, P.8
-
28
-
-
2442514340
-
Interactions between Sox9 and beta-catenin control chondrocyte differentiation
-
Akiyama H, JP Lyons, Y Mori-Akiyama, X Yang, R Zhang, Z Zhang, JM Deng, MM Taketo, T Nakamura, et al. (2004). Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev 18:1072-1087.
-
(2004)
Genes Dev
, vol.18
, pp. 1072-1087
-
-
Akiyama, H.1
Lyons, J.P.2
Mori-Akiyama, Y.3
Yang, X.4
Zhang, R.5
Zhang, Z.6
Deng, J.M.7
Taketo, M.M.8
Nakamura, T.9
-
29
-
-
21344447478
-
The canonical Wnt signaling pathway promotes chondrocyte differentiation in a Sox9-dependent manner
-
Yano F, F Kugimiya, S Ohba, T Ikeda, H Chikuda, T Ogasawara, N Ogata, T Takato, K Nakamura, H Kawaguchi and U-I Chung. (2005). The canonical Wnt signaling pathway promotes chondrocyte differentiation in a Sox9-dependent manner. Biochem Biophys Res Commun 333:1300-1308.
-
(2005)
Biochem Biophys Res Commun
, vol.333
, pp. 1300-1308
-
-
Yano, F.1
Kugimiya, F.2
Ohba, S.3
Ikeda, T.4
Chikuda, H.5
Ogasawara, T.6
Ogata, N.7
Takato, T.8
Nakamura, K.9
Kawaguchi, H.10
Chung, U.-I.11
-
30
-
-
59149089747
-
Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus
-
Topol L, W Chen, H Song, TF Day and Y Yang. (2009). Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus. J Biol Chem 284:3323-3333.
-
(2009)
J Biol Chem
, vol.284
, pp. 3323-3333
-
-
Topol, L.1
Chen, W.2
Song, H.3
Day, T.F.4
Yang, Y.5
-
31
-
-
0029027780
-
Developmental biology of the pancreas
-
Slack JM. (1995). Developmental biology of the pancreas. Development 121:1569-1580.
-
(1995)
Development
, vol.121
, pp. 1569-1580
-
-
Slack, J.M.1
-
32
-
-
70350225535
-
Vertebrate endoderm development and organ formation
-
Zorn AM and JM Wells. (2009). Vertebrate endoderm development and organ formation. Annu Rev Cell Dev Biol 25:221-251.
-
(2009)
Annu Rev Cell Dev Biol
, vol.25
, pp. 221-251
-
-
Zorn, A.M.1
Wells, J.M.2
-
33
-
-
33746903357
-
Definitive endoderm of the mouse embryo: Formation, cell fates, and morphogenetic function
-
Lewis SL and PPL Tam. (2006). Definitive endoderm of the mouse embryo: formation, cell fates, and morphogenetic function. Dev Dyn 235:2315-2329.
-
(2006)
Dev Dyn
, vol.235
, pp. 2315-2329
-
-
Lewis, S.L.1
Tam, P.P.L.2
-
34
-
-
0028869514
-
Expression of murine STF- 1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny
-
Guz Y, MR Montminy, R Stein, J Leonard, LW Gamer, CV Wright and G Teitelman. (1995). Expression of murine STF- 1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny. Development 121:11-18.
-
(1995)
Development
, vol.121
, pp. 11-18
-
-
Guz, Y.1
Montminy, M.R.2
Stein, R.3
Leonard, J.4
Gamer, L.W.5
Wright, C.V.6
Teitelman, G.7
-
35
-
-
78651228289
-
Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine
-
Furuyama K, Y Kawaguchi, H Akiyama, M Horiguchi, S Kodama, T Kuhara, S Hosokawa, A Elbahrawy, T Soeda, et al. (2011). Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine. Nat Genet 43:34-41.
-
(2011)
Nat Genet
, vol.43
, pp. 34-41
-
-
Furuyama, K.1
Kawaguchi, Y.2
Akiyama, H.3
Horiguchi, M.4
Kodama, S.5
Kuhara, T.6
Hosokawa, S.7
Elbahrawy, A.8
Soeda, T.9
-
36
-
-
0038002029
-
Expression of Sox transcription factors in the developing mouse pancreas
-
Lioubinski O, M Müller, M Wegner and M Sander. (2003). Expression of Sox transcription factors in the developing mouse pancreas. Dev Dyn 227:402-408.
-
(2003)
Dev Dyn
, vol.227
, pp. 402-408
-
-
Lioubinski, O.1
Müller, M.2
Wegner, M.3
Sander, M.4
-
37
-
-
0033606972
-
Notch signalling controls pancreatic cell differentiation
-
Apelqvist A, H Li, L Sommer, P Beatus, DJ Anderson, T Honjo, M Hrabe de Angelis, U Lendahl and H Edlund. (1999). Notch signalling controls pancreatic cell differentiation. Nature 400:877-881.
-
(1999)
Nature
, vol.400
, pp. 877-881
-
-
Apelqvist, A.1
Li, H.2
Sommer, L.3
Beatus, P.4
Anderson, D.J.5
Honjo, T.6
Hrabe De Angelis, M.7
Lendahl, U.8
Edlund, H.9
-
38
-
-
18544404101
-
Control of endodermal endocrine development by Hes-1
-
Jensen J, EE Pedersen, P Galante, J Hald, RS Heller, M Ishibashi, R Kageyama, F Guillemot, P Serup and OD Madsen. (2000). Control of endodermal endocrine development by Hes-1. Nat Genet 24:36-44.
-
(2000)
Nat Genet
, vol.24
, pp. 36-44
-
-
Jensen, J.1
Pedersen, E.E.2
Galante, P.3
Hald, J.4
Heller, R.S.5
Ishibashi, M.6
Kageyama, R.7
Guillemot, F.8
Serup, P.9
Madsen, O.D.10
-
39
-
-
84865277434
-
A Sox9/Fgf feed-forward loop maintains pancreatic organ identity
-
Seymour PA, HP Shih, NA Patell, KK Freude, R Xiel, CJ Lim and M Sander. (2012). A Sox9/Fgf feed-forward loop maintains pancreatic organ identity. Development 139:3363-3372.
-
(2012)
Development
, vol.139
, pp. 3363-3372
-
-
Seymour, P.A.1
Shih, H.P.2
Patell, N.A.3
Freude, K.K.4
Xiel, R.5
Lim, C.J.6
Sander, M.7
-
40
-
-
79960982596
-
Sox9-haploinsufficiency causes glucose intolerance in mice
-
Dubois CL, HP Shih, PA Seymour, NA Patel, JM Behrmann, V Ngo and M Sander. (2011). Sox9-haploinsufficiency causes glucose intolerance in mice. PLoS One 6:e23131.
-
(2011)
PLoS One
, vol.6
-
-
Dubois, C.L.1
Shih, H.P.2
Seymour, P.A.3
Patel, N.A.4
Behrmann, J.M.5
Ngo, V.6
Sander, M.7
-
41
-
-
84873111871
-
Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration
-
Pan FC, ED Bankaitis, D Boyer, X Xu, M Van de Casteele, MA Magnuson, H Heimberg and CV Wright. (2013). Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration. Development 140:751-764.
-
(2013)
Development
, vol.140
, pp. 751-764
-
-
Pan, F.C.1
Bankaitis, E.D.2
Boyer, D.3
Xu, X.4
Van De Casteele, M.5
Magnuson, M.A.6
Heimberg, H.7
Wright, C.V.8
-
42
-
-
83555163679
-
SOX9 regulates endocrine cell differentiation during human fetal pancreas development
-
McDonald E, J Li, M Krishnamurthy, GF Fellows, CG Goodyer and R Wang. (2012). SOX9 regulates endocrine cell differentiation during human fetal pancreas development. Int J Biochem Cell Biol 44:72-83.
-
(2012)
Int J Biochem Cell Biol
, vol.44
, pp. 72-83
-
-
McDonald, E.1
Li, J.2
Krishnamurthy, M.3
Fellows, G.F.4
Goodyer, C.G.5
Wang, R.6
-
43
-
-
2342457712
-
Beta cell differentiation during early human pancreas development
-
Piper K, S Brickwood, LW Turnpenny, IT Cameron, SG Ball, DI Wilson and NA Hanley. (2004). Beta cell differentiation during early human pancreas development. J Endocrinol 181:11-23.
-
(2004)
J Endocrinol
, vol.181
, pp. 11-23
-
-
Piper, K.1
Brickwood, S.2
Turnpenny, L.W.3
Cameron, I.T.4
Ball, S.G.5
Wilson, D.I.6
Hanley, N.A.7
-
44
-
-
0036340074
-
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors
-
Gu G, J Dubauskaite and DA Melton. (2002). Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development 129:2447-2457.
-
(2002)
Development
, vol.129
, pp. 2447-2457
-
-
Gu, G.1
Dubauskaite, J.2
Melton, D.A.3
-
46
-
-
0031798066
-
Notes from some crypt watchers: Regulation of renewal in the mouse intestinal epithelium
-
Stappenbeck TS, MH Wong, JR Saam, IU Mysorekar and JI Gordon. (1998). Notes from some crypt watchers: regulation of renewal in the mouse intestinal epithelium. Curr Opin Cell Biol 10:702-709.
-
(1998)
Curr Opin Cell Biol
, vol.10
, pp. 702-709
-
-
Stappenbeck, T.S.1
Wong, M.H.2
Saam, J.R.3
Mysorekar, I.U.4
Gordon, J.I.5
-
47
-
-
79955053506
-
Sry-box (Sox) transcription factors in gastrointestinal physiology and disease
-
Gracz AD and ST Magness. (2011). Sry-box (Sox) transcription factors in gastrointestinal physiology and disease. Am J Physiol Gastroint Liver Physiol 300:G503-G515.
-
(2011)
Am J Physiol Gastroint Liver Physiol
, vol.300
-
-
Gracz, A.D.1
Magness, S.T.2
-
48
-
-
20544447734
-
Notch signals control the fate of immature progenitor cells in the intestine
-
Fre S, M Huyghe, P Mourikis, S Robine, D Louvard and S Artavanis-Tsakonas. (2005). Notch signals control the fate of immature progenitor cells in the intestine. Nature 435:964-968.
-
(2005)
Nature
, vol.435
, pp. 964-968
-
-
Fre, S.1
Huyghe, M.2
Mourikis, P.3
Robine, S.4
Louvard, D.5
Artavanis-Tsakonas, S.6
-
49
-
-
20544460148
-
Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
-
van Es JH, ME van Gijn, O Riccio, M van den Born, M Vooijs, H Begthel, M Cozijnsen, S Robine, DJ Winton, F Radtke and H Clevers. (2005). Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature 435:959-963.
-
(2005)
Nature
, vol.435
, pp. 959-963
-
-
Van Es, J.H.1
Van Gijn, M.E.2
Riccio, O.3
Van Den Born, M.4
Vooijs, M.5
Begthel, H.6
Cozijnsen, M.7
Robine, S.8
Winton, D.J.9
Radtke, F.10
Clevers, H.11
-
50
-
-
0035824487
-
Requirement of Math1 for secretory cell lineage commitment in the mouse intestine
-
Yang Q, NA Bermingham, MJ Finegold and HY Zoghbi. (2001). Requirement of Math1 for secretory cell lineage commitment in the mouse intestine. Science 294:2155-2158.
-
(2001)
Science
, vol.294
, pp. 2155-2158
-
-
Yang, Q.1
Bermingham, N.A.2
Finegold, M.J.3
Zoghbi, H.Y.4
-
51
-
-
79952418471
-
Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium
-
Gerbe F, JH van Es, L Makrini, B Brulin, G Mellitzer, S Robine, B Romagnolo, NF Shroyer, J-F Bourgaux, et al. (2011). Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium. J Cell Biol 192:767-780.
-
(2011)
J Cell Biol
, vol.192
, pp. 767-780
-
-
Gerbe, F.1
Van Es, J.H.2
Makrini, L.3
Brulin, B.4
Mellitzer, G.5
Robine, S.6
Romagnolo, B.7
Shroyer, N.F.8
Bourgaux, J.-F.9
-
52
-
-
0034212390
-
Notch gene expression during pancreatic organogenesis
-
Lammert E, J Brown and DA Melton. (2000). Notch gene expression during pancreatic organogenesis. Mech Dev 94:199-203.
-
(2000)
Mech Dev
, vol.94
, pp. 199-203
-
-
Lammert, E.1
Brown, J.2
Melton, D.A.3
-
53
-
-
0033617522
-
Notch signaling: Cell fate control and signal integration in development
-
Artavanis-Tsakonas S, MD Rand and RJ Lake. (1999). Notch signaling: cell fate control and signal integration in development. Science 284:770-776.
-
(1999)
Science
, vol.284
, pp. 770-776
-
-
Artavanis-Tsakonas, S.1
Rand, M.D.2
Lake, R.J.3
-
54
-
-
33845299568
-
Notch, a universal arbiter of cell fate decisions
-
Ehebauer M, P Hayward and AM Arias. (2006). Notch, a universal arbiter of cell fate decisions. Science 314:1414-1415.
-
(2006)
Science
, vol.314
, pp. 1414-1415
-
-
Ehebauer, M.1
Hayward, P.2
Arias, A.M.3
-
55
-
-
84863088235
-
A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation
-
Shih HP, JL Kopp, M Sandhu, CL Dubois, PA Seymour, A Grapin-Botton and M Sander. (2012). A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation. Development 139:2488-2499.
-
(2012)
Development
, vol.139
, pp. 2488-2499
-
-
Shih, H.P.1
Kopp, J.L.2
Sandhu, M.3
Dubois, C.L.4
Seymour, P.A.5
Grapin-Botton, A.6
Sander, M.7
-
56
-
-
68549133582
-
Wnt signaling and stem cell control
-
Nusse R, C Fuerer, W Ching, K Harnish, C Logan, A Zeng, D ten Berge and Y Kalani. (2008). Wnt signaling and stem cell control. Cold Spring Harb Symp Quant Biol 73:59-66.
-
(2008)
Cold Spring Harb Symp Quant Biol
, vol.73
, pp. 59-66
-
-
Nusse, R.1
Fuerer, C.2
Ching, W.3
Harnish, K.4
Logan, C.5
Zeng, A.6
Ten Berge, D.7
Kalani, Y.8
-
57
-
-
59649100796
-
Wnt signaling controls the fate of mesenchymal stem cells
-
Ling L, V Nurcombe and SM Cool. (2009). Wnt signaling controls the fate of mesenchymal stem cells. Gene 433:1-7.
-
(2009)
Gene
, vol.433
, pp. 1-7
-
-
Ling, L.1
Nurcombe, V.2
Cool, S.M.3
-
58
-
-
34547107319
-
WNT signaling pathway and stem cell signaling network
-
Katoh M. (2007). WNT signaling pathway and stem cell signaling network. Clin Cancer Res 13:4042-4045.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4042-4045
-
-
Katoh, M.1
-
59
-
-
28444438841
-
Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells
-
Dravid G, Z Ye, H Hammond, G Chen, A Pyle, P Donovan, X Yu and L Cheng. (2005). Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells. Stem Cells 23:1489-1501.
-
(2005)
Stem Cells
, vol.23
, pp. 1489-1501
-
-
Dravid, G.1
Ye, Z.2
Hammond, H.3
Chen, G.4
Pyle, A.5
Donovan, P.6
Yu, X.7
Cheng, L.8
-
60
-
-
55949121679
-
Wnt-mediated self-renewal of neural stem/progenitor cells
-
Kalani MY, SH Cheshier, BJ Cord, SR Bababeygy, H Vogel, IL Weissman, TD Palmer and R Nusse. (2008). Wnt-mediated self-renewal of neural stem/progenitor cells. Proc Natl Acad Sci U S A 105:16970-16975.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 16970-16975
-
-
Kalani, M.Y.1
Cheshier, S.H.2
Cord, B.J.3
Bababeygy, S.R.4
Vogel, H.5
Weissman, I.L.6
Palmer, T.D.7
Nusse, R.8
-
61
-
-
0037737726
-
Wnt proteins are lipid-modified and can act as stem cell growth factors
-
Willert K, JD Brown, E Danenberg, AW Duncan, IL Weissman, T Reya, JR Yates and R Nusse. (2003). Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature 423:448-452.
-
(2003)
Nature
, vol.423
, pp. 448-452
-
-
Willert, K.1
Brown, J.D.2
Danenberg, E.3
Duncan, A.W.4
Weissman, I.L.5
Reya, T.6
Yates, J.R.7
Nusse, R.8
-
62
-
-
46549083928
-
Control of chondrogenesis by the transcription factor Sox9
-
Akiyama H. (2008). Control of chondrogenesis by the transcription factor Sox9. Mod Rheumatol 18:213-219.
-
(2008)
Mod Rheumatol
, vol.18
, pp. 213-219
-
-
Akiyama, H.1
-
63
-
-
70349932747
-
Towards an integrated view of Wnt signaling in development
-
van Amerongen R and R Nusse. (2009). Towards an integrated view of Wnt signaling in development. Development 136:3205-3214.
-
(2009)
Development
, vol.136
, pp. 3205-3214
-
-
Van Amerongen, R.1
Nusse, R.2
-
64
-
-
67650230896
-
Wnt/beta-catenin signaling: Components, mechanisms, and diseases
-
MacDonald BT, K Tamai and X He. (2009). Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell 17:9-26.
-
(2009)
Dev Cell
, vol.17
, pp. 9-26
-
-
MacDonald, B.T.1
Tamai, K.2
He, X.3
-
65
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers H. (2006). Wnt/beta-catenin signaling in development and disease. Cell 127:469-480.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
66
-
-
39849091185
-
Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2
-
Li C, H Chen, L Hu, Y Xing, T Sasaki, MF Villosis, J Li, M Nishita, Y Minami and P Minoo. (2008). Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2. BMC Mol Biol 9:11.
-
(2008)
BMC Mol Biol
, vol.9
, pp. 11
-
-
Li, C.1
Chen, H.2
Hu, L.3
Xing, Y.4
Sasaki, T.5
Villosis, M.F.6
Li, J.7
Nishita, M.8
Minami, Y.9
Minoo, P.10
-
67
-
-
33646241997
-
Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context
-
Mikels AJ and R Nusse. (2006). Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context. PLoS Biol 4:e115.
-
(2006)
PLoS Biol
, vol.4
-
-
Mikels, A.J.1
Nusse, R.2
-
68
-
-
78349276165
-
Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors
-
Grumolato L, G Liu, P Mong, R Mudbhary, R Biswas, R Arroyave, S Vijayakumar, AN Economides and SA Aaronson. (2010). Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors. Genes Dev 24:2517-2530.
-
(2010)
Genes Dev
, vol.24
, pp. 2517-2530
-
-
Grumolato, L.1
Liu, G.2
Mong, P.3
Mudbhary, R.4
Biswas, R.5
Arroyave, R.6
Vijayakumar, S.7
Economides, A.N.8
Aaronson, S.A.9
-
69
-
-
17844363974
-
Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes
-
Hill TP, D Später, MM Taketo, W Birchmeier and C Hartmann. (2005). Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes. Dev Cell 8:727-738.
-
(2005)
Dev Cell
, vol.8
, pp. 727-738
-
-
Hill, T.P.1
Später, D.2
Taketo, M.M.3
Birchmeier, W.4
Hartmann, C.5
-
70
-
-
0030975671
-
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma
-
Korinek V, N Barker, PJ Morin, D van Wichen, R de Weger, KW Kinzler, B Vogelstein and H Clevers. (1997). Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma. Science 275:1784-1787.
-
(1997)
Science
, vol.275
, pp. 1784-1787
-
-
Korinek, V.1
Barker, N.2
Morin, P.J.3
Van Wichen, D.4
De Weger, R.5
Kinzler, K.W.6
Vogelstein, B.7
Clevers, H.8
-
71
-
-
0026630266
-
APC mutations occur early during colorectal tumorigenesis
-
Powell SM, N Zilz, Y Beazer-Barclay, TM Bryan, SR Hamilton, SN Thibodeau, B Vogelstein and KW Kinzler. (1992). APC mutations occur early during colorectal tumorigenesis. Nature 359:235-237.
-
(1992)
Nature
, vol.359
, pp. 235-237
-
-
Powell, S.M.1
Zilz, N.2
Beazer-Barclay, Y.3
Bryan, T.M.4
Hamilton, S.R.5
Thibodeau, S.N.6
Vogelstein, B.7
Kinzler, K.W.8
-
72
-
-
18644373146
-
The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
-
van de Wetering M, E Sancho, C Verweij, Wde Lau, I Oving, A Hurlstone, K van der Horn, E Batlle, D Coudreuse, et al. (2002). The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell 111:241-250.
-
(2002)
Cell
, vol.111
, pp. 241-250
-
-
Van De Wetering, M.1
Sancho, E.2
Verweij, C.3
Lau, W.4
Oving, I.5
Hurlstone, A.6
Van Der Horn, K.7
Batlle, E.8
Coudreuse, D.9
-
73
-
-
18644376279
-
Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB
-
Batlle E, JT Henderson, H Beghtel, MMW van den Born, E Sancho, G Huls, J Meeldijk, J Robertson, M van de Wetering, T Pawson and H Clevers. (2002). Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB. Cell 111:251-263.
-
(2002)
Cell
, vol.111
, pp. 251-263
-
-
Batlle, E.1
Henderson, J.T.2
Beghtel, H.3
Born Den-Van, W.M.M.4
Sancho, E.5
Huls, G.6
Meeldijk, J.7
Robertson, J.8
Wetering Van-De, M.9
Pawson, T.10
Clevers, H.11
-
74
-
-
0031848068
-
Depletion of epithelial stemcell compartments in the small intestine of mice lacking Tcf-4
-
Korinek V, N Barker, P Moerer, E van Donselaar, G Huls, PJ Peters and H Clevers. (1998). Depletion of epithelial stemcell compartments in the small intestine of mice lacking Tcf-4. Nat Genet 19:379-383.
-
(1998)
Nat Genet
, vol.19
, pp. 379-383
-
-
Korinek, V.1
Barker, N.2
Moerer, P.3
Van Donselaar, E.4
Huls, G.5
Peters, P.J.6
Clevers, H.7
-
75
-
-
78751644734
-
Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
-
Sato T, JH van Es, HJ Snippert, DE Stange, RG Vries, M van den Born, N Barker, NF Shroyer, M van de Wetering and H Clevers. (2011). Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts. Nature 469:415-418.
-
(2011)
Nature
, vol.469
, pp. 415-418
-
-
Sato, T.1
Van Es, J.H.2
Snippert, H.J.3
Stange, D.E.4
Vries, R.G.5
Van Den Born, M.6
Barker, N.7
Shroyer, N.F.8
Van De-Wetering, M.9
Clevers, H.10
-
76
-
-
77955284526
-
SOX10 structure-function analysis in the chicken neural tube reveals important insights into its role in human neurocristopathies
-
Cossais F, M Wahlbuhl, J Kriesch and M Wegner. (2010). SOX10 structure-function analysis in the chicken neural tube reveals important insights into its role in human neurocristopathies. Hum Mol Genet 19:2409-2420.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 2409-2420
-
-
Cossais, F.1
Wahlbuhl, M.2
Kriesch, J.3
Wegner, M.4
-
78
-
-
0346157329
-
The ins and outs of transcriptional control: Nucleocytoplasmic shuttling in development and disease
-
Smith JM and PA Koopman. (2004). The ins and outs of transcriptional control: nucleocytoplasmic shuttling in development and disease. Trends Genet 20:4-8.
-
(2004)
Trends Genet
, vol.20
, pp. 4-8
-
-
Smith, J.M.1
Koopman, P.A.2
-
79
-
-
77952724644
-
Heterozygous SOX9 mutations allowing for residual DNA-binding and transcriptional activation lead to the acampomelic variant of campomelic dysplasia
-
Staffler A, M Hammel, M Wahlbuhl, C Bidlingmaier, AW Flemmer, P Pagel, T Nicolai, M Wegner and A Holzinger. (2010). Heterozygous SOX9 mutations allowing for residual DNA-binding and transcriptional activation lead to the acampomelic variant of campomelic dysplasia. Hum Mutat 31:E1436-E1444.
-
(2010)
Hum Mutat
, vol.31
-
-
Staffler, A.1
Hammel, M.2
Wahlbuhl, M.3
Bidlingmaier, C.4
Flemmer, A.W.5
Pagel, P.6
Nicolai, T.7
Wegner, M.8
Holzinger, A.9
-
80
-
-
0029977067
-
Sex reversal by loss of the C-terminal transactivation domain of human SOX9
-
Sudbeck P, ML Schmitz, PA Baeuerle and G Scherer. (1996). Sex reversal by loss of the C-terminal transactivation domain of human SOX9. Nat Genet 13:230-232.
-
(1996)
Nat Genet
, vol.13
, pp. 230-232
-
-
Sudbeck, P.1
Schmitz, M.L.2
Baeuerle, P.A.3
Scherer, G.4
|