RNF43 germline and somatic mutation in serrated neoplasia pathway and its association with BRAF mutation

Gut

Volumn 66, Issue 9, 2017, Pages 1645-1656

  Yan, Helen H N ^b   Lai, Jeffrey C W ^b   Ho, Siu Lun ^b   Leung, Wai Keung ^b   Law, Wai Lun ^b   Lee, Janet F Y ^c   Chan, Anthony K W ^b   Tsui, Wai Yin ^b   Chan, Annie S Y ^b   Lee, Bernard C H ^b   Yue, Sarah S K ^b   Man, Alice H Y ^b   Clevers, Hans ^d   Yuen, Siu Tsan ^a,b   Leung, Suet Yi ^b  

^a Department of Pathology St Paul’s Hospital ^*  (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; B RAF KINASE; BETA CATENIN; RNF43 PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; WNT PROTEIN; BRAF PROTEIN, HUMAN; DNA BINDING PROTEIN; MUTL PROTEIN HOMOLOG 1; ONCOPROTEIN; RNF43 PROTEIN, HUMAN;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; BRAF GENE; COHORT ANALYSIS; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE MARKER; FAMILY STUDY; FEMALE; GENE; GENE IDENTIFICATION; GENE INACTIVATION; GENE MUTATION; GENETIC DISORDER; GERM LINE; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; HUMAN TISSUE; INTESTINE POLYP; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE MARKER; MOUSE; NONHUMAN; ORGANOID; PHENOTYPE; PRIORITY JOURNAL; RNF43 GENE; SANGER SEQUENCING; SOMATIC MUTATION; VALIDATION STUDY; WHOLE EXOME SEQUENCING; WNT SIGNALING; ADENOMA; COLON POLYP; COLORECTAL TUMOR; FAMILY; GENETIC PREDISPOSITION; GENETIC SCREENING; GENETICS; HONG KONG; METABOLISM; MICROSATELLITE INSTABILITY; MIDDLE AGED; MUTATION; PATHOLOGY; PHYSIOLOGY; PROCEDURES;

ADENOMA; ADULT; COLONIC POLYPS; COLORECTAL NEOPLASMS; DNA-BINDING PROTEINS; FAMILY; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; HONG KONG; HUMANS; MALE; MICROSATELLITE INSTABILITY; MIDDLE AGED; MUTATION; MUTL PROTEIN HOMOLOG 1; ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS B-RAF; WNT SIGNALING PATHWAY;

EID: 84977507464     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2016-311849     Document Type: Article

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