Exome Resequencing Identifies Potential Tumor-Suppressor Genes that Predispose to Colorectal Cancer

Human Mutation

Volumn 34, Issue 7, 2013, Pages 1026-1034

  Smith, Christopher G ^a   Naven, Marc ^a   Harris, Rebecca ^a   Colley, James ^a   West, Hannah ^a   Li, Ning ^b   Liu, Yuan ^b   Adams, Richard ^a   Maughan, Timothy S ^c   Nichols, Laura ^d   Kaplan, Richard ^d   Wagner, Michael J ^e   Mcleod, Howard L ^e   Cheadle, Jeremy P ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b Copenhagen Bio Science Park ^*  (Denmark)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d MRC CLINICAL TRIALS UNIT   (United Kingdom)

^e University of North Carolina   (United States)

Author keywords

Colorectal cancer; Exome resequencing; LOH; Tumor suppressor

Indexed keywords

ADULT; AGED; ALLELE; ARTICLE; CANCER SUSCEPTIBILITY; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; EXOME; FANCM GENE; FEMALE; FRAMESHIFT MUTATION; GENE; GENE INACTIVATION; GENE INSERTION; GENE SEQUENCE; GENETIC PREDISPOSITION; GERM LINE; GROUPS BY AGE; HETEROZYGOTE; HOMEOSTASIS; HUMAN; HUMAN TISSUE; INDEL MUTATION; LAMB4 GENE; LAMC3 GENE; MALE; NONSENSE MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PTCHD3 GENE; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC MUTATION; SPLICING DEFECT; TREX2 GENE; TUMOR SUPPRESSOR GENE;

ADENOMATOUS POLYPOSIS COLI PROTEIN; COLORECTAL NEOPLASMS; COMPUTATIONAL BIOLOGY; DNA POLYMERASE II; EXOME; GENES, TUMOR SUPPRESSOR; GENETIC PREDISPOSITION TO DISEASE; GENOME, HUMAN; GERM-LINE MUTATION; HUMANS; RECEPTORS, NOTCH; SEQUENCE ANALYSIS, DNA;

EID: 84879409534     PISSN: 10597794     EISSN: 10981004     Source Type: Journal    
DOI: 10.1002/humu.22333     Document Type: Article

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