Frequent PTPRK-RSPO3 fusions and RNF43 mutations in colorectal traditional serrated adenoma

Journal of Pathology

Volumn 239, Issue 2, 2016, Pages 133-138

  Sekine, Shigeki ^a,b   Yamashita, Satoshi ^b   Tanabe, Taro ^a   Hashimoto, Taiki ^a   Yoshida, Hiroshi ^a   Taniguchi, Hirokazu ^a   Kojima, Motohiro ^c   Shinmura, Kazuya ^d   Saito, Yutaka ^a   Hiraoka, Nobuyoshi ^a,b   Ushijima, Toshikazu ^b   Ochiai, Atsushi ^a,c  

^a NATIONAL CANCER CENTER HOSPITAL   (Japan)

^b NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^c NATIONAL CANCER CENTER HOSPITAL EAST   (Japan)

^d HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

large intestine; R spondin; RNF43; traditional serrated adenoma; WNT

Indexed keywords

BETA CATENIN; DNA BINDING PROTEIN; ONCOPROTEIN; PTPRK PROTEIN, HUMAN; RECEPTOR LIKE PROTEIN TYROSINE PHOSPHATASE; RNF43 PROTEIN, HUMAN; RSPO3 PROTEIN, HUMAN; THROMBOSPONDIN;

ADENOMATOUS POLYP; APC GENE; ARTICLE; COLORECTAL ADENOMA; COLORECTAL POLYP; GENE; GENE FUSION; GENE MUTATION; HUMAN; HUMAN TISSUE; HYPERPLASTIC POLYP; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MUTATIONAL ANALYSIS; NEXT GENERATION SEQUENCING; PRIORITY JOURNAL; PTPRK GENE; RECTUM ADENOMA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNF43 GENE; RSPO3 GENE; TRADITIONAL SERRATED ADENOMA; TUBULOVILLOUS ADENOMA; WNT SIGNALING PATHWAY; ADENOMA; AGED; CELL TRANSFORMATION; COLORECTAL TUMOR; DNA MUTATIONAL ANALYSIS; DNA SEQUENCE; FEMALE; GENETICS; HYPERPLASIA; INTESTINE; INTESTINE POLYP; MALE; METABOLISM; MUTATION; PATHOLOGY;

ADENOMA; AGED; BETA CATENIN; CELL TRANSFORMATION, NEOPLASTIC; COLORECTAL NEOPLASMS; DNA MUTATIONAL ANALYSIS; DNA-BINDING PROTEINS; FEMALE; HUMANS; HYPERPLASIA; INTESTINAL POLYPS; INTESTINES; MALE; MUTATION; ONCOGENE FUSION; ONCOGENE PROTEINS; RECEPTOR-LIKE PROTEIN TYROSINE PHOSPHATASES, CLASS 2; SEQUENCE ANALYSIS, DNA; THROMBOSPONDINS; WNT SIGNALING PATHWAY;

EID: 84962915387     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4709     Document Type: Article

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