Consumption of fruit and vegetables and risk of frailty: A dose-response analysis of 3 prospective cohorts of community-dwelling older adults

American Journal of Clinical Nutrition

Volumn 104, Issue 1, 2016, Pages 132-142

  García Esquinas, Esther ^a,b,c   Rahi, Berna ^d,e   Peres, Karine ^d,e   Colpo, Marco ^f   Dartigues, Jean François ^d,e   Bandinelli, Stefania ^g   Feart, Catherine ^d,e   Rodríguez Artalejo, Fernando ^a,b,c  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b HOSPITAL UNIVERSITARIO LA PAZ IDIPAZ   (Spain)

^c CIBER EPIDEMIOLOGÍA Y SALUD PÚBLICA CIBERESP   (Spain)

^d French Institute of Health and Medical Research   (France)

^e UNIVERSITÉ DE BORDEAUX   (France)

^f UNIVERSITY OF FLORENCE   (Italy)

^g Florence Health Agency   (Italy)

Author keywords

Elderly; Exhaustion; Frailty; Fruits; Slow walking speed; Vegetables

Indexed keywords

AGED; ARTICLE; CONTROLLED STUDY; CORRELATIONAL STUDY; EXHAUSTION; FEMALE; FOLLOW UP; FOOD FREQUENCY QUESTIONNAIRE; FOOD INTAKE; FRAIL ELDERLY; FRUIT; GERIATRIC NUTRITION; HUMAN; MAJOR CLINICAL STUDY; MALE; PHYSICAL ACTIVITY; PROSPECTIVE STUDY; RISK REDUCTION; VEGETABLE; WALKING SPEED; WEIGHT REDUCTION; DIET; EXERCISE; FATIGUE; FEEDING BEHAVIOR; GAIT; MIDDLE AGED; RISK; RISK ASSESSMENT; RISK FACTOR; SPAIN;

AGED; DIET; DIET SURVEYS; EXERCISE; FATIGUE; FEEDING BEHAVIOR; FEMALE; FRAIL ELDERLY; FRUIT; GAIT; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RISK; RISK ASSESSMENT; RISK FACTORS; SPAIN; VEGETABLES; WEIGHT LOSS;

EID: 84977156207     PISSN: 00029165     EISSN: 19383207     Source Type: Journal    
DOI: 10.3945/ajcn.115.125781     Document Type: Article

References (58)

1. Dauchet L, Amouyel P, Hercberg S, Dallongeville J. Fruit and vegetable consumption and risk of coronary heart disease: a meta-analysis of cohort studies. J Nutr 2006;136:2588-93.
2. He FJ, Nowson CA, Lucas M, MacGregor GA. Increased consumption of fruit and vegetables is related to a reduced risk of coronary heart disease: meta-analysis of cohort studies. J Hum Hypertens 2007;21:717-28.
3. Hu D, Huang J, Wang Y, Zhang D, Qu Y. Fruits and vegetables consumption and risk of stroke: a meta-analysis of prospective cohort studies. Stroke 2014;45:1613-9.
4. Johnson CM, Wei C, Ensor JE, Smolenski DJ, Amos CI, Levin B, Berry DA. Meta-analyses of colorectal cancer risk factors. Cancer Causes Control 2013;24:1207-22.
5. Jung S, Spiegelman D, Baglietto L, Bernstein L, Boggs DA, van den Brandt PA, Buring JE, Cerhan JR, Gaudet MM, Giles GG, et al. Fruit and vegetable intake and risk of breast cancer by hormone receptor status. J Natl Cancer Inst 2013;105:219-36.
6. Chen GC, Lv DB, Pang Z, Liu QF. Fruits and vegetables consumption and risk of non-Hodgkin's lymphoma: a meta-analysis of observational studies. Int J Cancer 2013;133:190-200.
7. Liu H, Wang XC, Hu GH, Guo ZF, Lai P, Xu L, Huang TB, Xu YF. Fruit and vegetable consumption and risk of bladder cancer: an updated meta-analysis of observational studies. Eur J Cancer Prev 2015;24:508-16.
8. Wang X, Ouyang Y, Liu J, Zhu M, Zhao G, Bao W, Hu FB. Fruit and vegetable consumption and mortality from all causes, cardiovascular disease, and cancer: systematic review and dose-response meta-analysis of prospective cohort studies. BMJ 2014;349:g4490.
9. Houston DK, Stevens J, Cai J, Haines PS. Dairy, fruit, and vegetable intakes and functional limitations and disability in a biracial cohort: the Atherosclerosis Risk in Communities Study. Am J Clin Nutr 2005;81:515-22.
10. Tomey KM, Sowers MR, Crandall C, Johnston J, Jannausch M, Yosef M. Dietary intake related to prevalent functional limitations in midlife women. Am J Epidemiol 2008;167:935-43.
11. Myint PK, Welch AA, Bingham SA, Surtees PG, Wainwright NW, Luben RN, Wareham NJ, Smith RD, Harvey IM, Day NE, et al. Fruit and vegetable consumption and self-reported functional health in men and women in the European Prospective Investigation into Cancer-Norfolk (EPIC-Norfolk): a population-based cross-sectional study. Public Health Nutr 2007;10:34-41.
12. Sabia S, Elbaz A, Rouveau N, Brunner EJ, Kivimaki M, Singh-Manoux A. Cumulative associations between midlife health behaviors and physical functioning in early old age: a 17-year prospective cohort study. J Am Geriatr Soc 2014;62:1860-8.
13. Tsai AC, Chang TL, Chi SH. Frequent consumption of vegetables predicts lower risk of depression in older Taiwanese - results of a prospective population-based study. Public Health Nutr 2012;15:1087-92.
14. Loef M, Walach H. Fruit, vegetables and prevention of cognitive decline or dementia: a systematic review of cohort studies. J Nutr Health Aging 2012;16:626-30.
15. Artaud F, Dugravot A, Sabia S, Singh-Manoux A, Tzourio C, Elbaz A. Unhealthy behaviours and disability in older adults: three-City Dijon cohort study. BMJ 2013;347:f4240.
16. Semba RD, Varadhan R, Bartali B, Ferrucci L, Ricks MO, Blaum C, Fried LP. Low serum carotenoids and development of severe walking disability among older women living in the community: the women's health and aging study I. Age Ageing 2007;36:62-7.
17. Alipanah N, Varadhan R, Sun K, Ferrucci L, Fried LP, Semba RD. Low serum carotenoids are associated with a decline in walking speed in older women. J Nutr Health Aging 2009;13:170-5.
18. Gopinath B, Russell J, Flood VM, Burlutsky G, Mitchell P. Adherence to dietary guidelines positively affects quality of life and functional status of older adults. J Acad Nutr Diet 2014;114:220-9.
19. Neville CE, Young IS, Gilchrist SE, McKinley MC, Gibson A, Edgar JD, Woodside JV. Effect of increased fruit and vegetable consumption on physical function and muscle strength in older adults. Age (Dordr) 2013;35:2409-22.
20. Lauretani F, Semba RD, Bandinelli S, Dayhoff-Brannigan M, Giacomini V, Corsi AM, Guralnik JM, Ferrucci L. Low plasma carotenoids and skeletal muscle strength decline over 6 years. J Gerontol A Biol Sci Med Sci 2008;63:376-83.
21. Liu ZM, Leung J, Wong SY, Wong CK, Chan R, Woo J. Greater fruit intake was associated with better bone mineral status among Chinese elderly men and women: results of Hong Kong Mr. Os and Ms. Os studies. J Am Med Dir Assoc 2015;16:309-15.
22. Tucker KL, Hannan MT, Chen H, Cupples LA, Wilson PW, Kiel DP. Potassium, magnesium, and fruit and vegetable intakes are associated with greater bone mineral density in elderly men and women. Am J Clin Nutr 1999;69:727-36.
23. Nicklett EJ, Semba RD, Xue QL, Tian J, Sun K, Cappola AR, Simonsick EM, Ferrucci L, Fried LP. Fruit and vegetable intake, physical activity, and mortality in older community-dwelling women. J Am Geriatr Soc 2012;60:862-8.
24. Akbaraly TN, Favier A, Berr C. Total plasma carotenoids and mortality in the elderly: results of the Epidemiology of Vascular Ageing (EVA) study. Br J Nutr 2009;101:86-92.
25. Gaziano JM, Manson JE, Branch LG, Colditz GA, Willett WC, Buring JE. A prospective study of consumption of carotenoids in fruits and vegetables and decreased cardiovascular mortality in the elderly. Ann Epidemiol 1995;5:255-60.
26. Clegg A, Young J, Iliffe S, Rikkert MO, Rockwood K. Frailty in elderly people. Lancet 2013;381:752-62.
27. Collard RM, Boter H, Schoevers RA, Oude Voshaar RC. Prevalence of frailty in community-dwelling older persons: a systematic review. J Am Geriatr Soc 2012;60:1487-92.
28. Bouillon K, Kivimaki M, Hamer M, Shipley MJ, Akbaraly TN, Tabak A, Singh-Manoux A, Batty GD. Diabetes risk factors, diabetes risk algorithms, and the prediction of future frailty: the Whitehall II prospective cohort study. J Am Med Dir Assoc 2013;14:851.e1-6.
29. Kobayashi S, Asakura K, Suga H, Sasaki S. Inverse association between dietary habits with high total antioxidant capacity and prevalence of frailty among elderly Japanese women: a multicenter crosssectional study. J Nutr Health Aging 2014;18:827-39.
30. Léon-Munoz LM, Guallar-Castillon P, Lopez-Garcia E, Rodriguez-Artalejo F. Mediterranean diet and risk of frailty in community-dwelling older adults. J Am Med Dir Assoc 2014;15:899-903.
31. Rodríguez-Artalejo F, Graciani A, Guallar-Castillon P, Leon-Munoz LM, Zuluaga MC, Lopez-Garcia E, Gutierrez-Fisac JL, Taboada JM, Aguilera MT, Regidor E, et al. [Rationale and methods of the study on nutrition and cardiovascular risk in Spain (ENRICA).] Rev Esp Cardiol 2011;64:876-82.
32. 3C Study Group. Vascular factors and risk of dementia: design of the Three-City Study and baseline characteristics of the study population. Neuroepidemiology 2003;22:316-25.
33. Pérès K, Matharan F, Allard M, Amieva H, Baldi I, Barberger-Gateau P, Bergua V, Bourdel-Marchasson I, Delcourt C, Foubert-Samier A, et al. Health and aging in elderly farmers: the AMI cohort. BMC Public Health 2012;12:558.
34. Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, Seeman T, Tracy R, Kop WJ, Burke G, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 2001;56:M146-56.
35. Lyness JM, Noel TK, Cox C, King DA, Conwell Y, Caine ED. Screening for depression in elderly primary care patients. A comparison of the Center for Epidemiologic Studies-Depression Scale and the Geriatric Depression Scale. Arch Intern Med 1997;157:449-54.
36. Ottenbacher KJ, Branch LG, Ray L, Gonzales VA, Peek MK, Hinman MR. The reliability of upper- and lower-extremity strength testing in a community survey of older adults. Arch Phys Med Rehabil 2002;83:1423-7.
37. Avila-Funes JA, Carcaillon L, Helmer C, Carriere I, Ritchie K, Rouaud O, Tzourio C, Dartigues JF, Amieva H. Is frailty a prodromal stage of vascular dementia? Results from the Three-City Study. J Am Geriatr Soc 2012;60:1708-12.
38. Guralnik JM, Simonsick EM, Ferrucci L, Glynn RJ, Berkman LF, Blazer DG, Scherr PA, Wallace RB. A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol 1994;49:M85-94.
39. Alexander NB, Guire KE, Thelen DG, Ashton-Miller JA, Schultz AB, Grunawalt JC, Giordani B. Self-reported walking ability predicts functional mobility performance in frail older adults. J Am Geriatr Soc 2000;48:1408-13.
40. Relative validity and reproducibility of a diet history questionnaire in Spain. I. Foods. EPIC Group of Spain. European Prospective Investigation into Cancer and Nutrition. Int J Epidemiol 1997;26(Suppl 1):S91-9.
41. Guallar-Castillón P, Sagardui-Villamor J, Balboa-Castillo T, Sala-Vila A, Ariza Astolfi MJ, Sarrion Pelous MD, Leon-Munoz LM, Graciani A, Laclaustra M, Benito C, et al. Validity and reproducibility of a Spanish dietary history. PLoS One 2014;9:e86074.
42. Samieri C, Jutand MA, Feart C, Capuron L, Letenneur L, Barberger-Gateau P. Dietary patterns derived by hybrid clustering method in older people: association with cognition, mood, and self-rated health. J Am Diet Assoc 2008;108:1461-71.
43. Spanish Society of Community Nutrition and Spanish Society of Family Medicine and Community Health. Consejos para una alimentación saludable. [Advice for healthy nutrition.] [Internet]. c2007; [cited 2016 Apr 27]. Available from: http://www.semfyc.es/pfw-files/cma/Informacion/modulo/documentos/guia-alimentacion.pdf.
44. Féart C, Jutand MA, Larrieu S, Letenneur L, Delcourt C, Combe N, Barberger-Gateau P. Energy, macronutrient and fatty acid intake of French elderly community dwellers and association with sociodemographic characteristics: data from the Bordeaux sample of the Three-City Study. Br J Nutr 2007;98:1046-57.
45. Féart C, Alles B, Merle B, Samieri C, Barberger-Gateau P. Adherence to a Mediterranean diet and energy, macro-, and micronutrient intakes in older persons. J Physiol Biochem 2012;68:691-700.
46. Trichopoulou A, Costacou T, Bamia C, Trichopoulos D. Adherence to a Mediterranean diet and survival in a Greek population. N Engl J Med 2003;348:2599-608.
47. Lawton MP, Brody EM. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist 1969;9:179-86.
48. Folstein MF, Folstein SE, McHugh PR. "Mini-mental state." A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189-98.
49. Lauretani F, Semba RD, Bandinelli S, Dayhoff-Brannigan M, Lauretani F, Corsi AM, Guralnik JM, Ferrucci L. Carotenoids as protection against disability in older persons. Rejuvenation Res 2008;11:557-63.
50. Kim J, Lee Y, Kye S, Chung YS, Kim KM. Association of vegetables and fruits consumption with sarcopenia in older adults: the Fourth Korea National Health and Nutrition Examination Survey. Age Ageing 2015;44:96-102.
51. Wu IC, Shiesh SC, Kuo PH, Lin XZ. High oxidative stress is correlated with frailty in elderly Chinese. J Am Geriatr Soc 2009;57:1666-71.
52. Inglés M, Gambini J, Carnicero JA, Garcia-Garcia FJ, Rodriguez-Manas L, Olaso-Gonzalez G, Dromant M, Borras C, Vina J. Oxidative stress is related to frailty, not to age or sex, in a geriatric population: lipid and protein oxidation as biomarkers of frailty. J Am Geriatr Soc 2014;62:1324-8.
53. Lampe JW. Health effects of vegetables and fruit: assessing mechanisms of action in human experimental studies. Am J Clin Nutr 1999;70:475S-90S.
54. Heber D. Vegetables, fruits and phytoestrogens in the prevention of diseases. J Postgrad Med 2004;50:145-9.
55. Li H, Manwani B, Leng SX. Frailty, inflammation, and immunity. Aging Dis 2011;2:466-73.
56. Slavin JL, Lloyd B. Health benefits of fruits and vegetables. Adv Nutr 2012;3:506-16.
57. Dawson-Hughes B, Harris SS, Ceglia L. Alkaline diets favor lean tissue mass in older adults. Am J Clin Nutr 2008;87:662-5.
58. Gibson A, Edgar JD, Neville CE, Gilchrist SE, McKinley MC, Patterson CC, Young IS, Woodside JV. Effect of fruit and vegetable consumption on immune function in older people: a randomized controlled trial. Am J Clin Nutr 2012;96:1429-36.