메뉴 건너뛰기




Volumn 3, Issue AUG, 2015, Pages

The Granulocyte-colony stimulating factor has a dual role in neuronal and vascular plasticity

Author keywords

ALS; Angiogenesis; Arteriogenesis; G CSF; Neurogenesis; Neuroregeneration; Plasticity; SCI

Indexed keywords


EID: 84976376309     PISSN: None     EISSN: 2296634X     Source Type: Journal    
DOI: 10.3389/fcell.2015.00048     Document Type: Review
Times cited : (55)

References (83)
  • 1
    • 84926373667 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor for amyotrophic lateral sclerosis: a randomized, double-blind, placebo-controlled study of Iranian patients
    • Amirzagar, N., Nafissi, S., Tafakhori, A., Modabbernia, A., Amirzargar, A., Ghaffarpour, M., et al. (2015). Granulocyte colony-stimulating factor for amyotrophic lateral sclerosis: a randomized, double-blind, placebo-controlled study of Iranian patients. J. Clin. Neurol. 11, 164-171. doi: 10.3988/jcn.2015.11.2.164
    • (2015) J. Clin. Neurol , vol.11 , pp. 164-171
    • Amirzagar, N.1    Nafissi, S.2    Tafakhori, A.3    Modabbernia, A.4    Amirzargar, A.5    Ghaffarpour, M.6
  • 2
    • 0042574218 scopus 로고    scopus 로고
    • Therapeutic induction of arteriogenesis in hypoperfused rat brain via granulocyte-macrophage colony-stimulating factor
    • Buschmann, I. R., Busch, H. J., Mies, G., and Hossmann, K. A. (2003). Therapeutic induction of arteriogenesis in hypoperfused rat brain via granulocyte-macrophage colony-stimulating factor. Circulation 108, 610-615. doi: 10.1161/01.CIR.0000074209.17561.99
    • (2003) Circulation , vol.108 , pp. 610-615
    • Buschmann, I.R.1    Busch, H.J.2    Mies, G.3    Hossmann, K.A.4
  • 3
    • 0035203155 scopus 로고    scopus 로고
    • GM-CSF: a strong arteriogenic factor acting by amplification of monocyte function
    • Buschmann, I. R., Hoefer, I. E., van Royen, N., Katzer, E., Braun-Dulleaus, R., Heil, M., et al. (2001). GM-CSF: a strong arteriogenic factor acting by amplification of monocyte function. Atherosclerosis 159, 343-356. doi: 10.1016/S0021-9150(01)00637-2
    • (2001) Atherosclerosis , vol.159 , pp. 343-356
    • Buschmann, I.R.1    Hoefer, I.E.2    van Royen, N.3    Katzer, E.4    Braun-Dulleaus, R.5    Heil, M.6
  • 4
    • 0033439675 scopus 로고    scopus 로고
    • Arteriogenesis versus angiogenesis: two mechanisms of vessel growth
    • Buschmann, I., and Schaper, W. (1999). Arteriogenesis versus angiogenesis: two mechanisms of vessel growth. News Physiol. Sci. 14, 121-125
    • (1999) News Physiol. Sci , vol.14 , pp. 121-125
    • Buschmann, I.1    Schaper, W.2
  • 5
    • 0034094342 scopus 로고    scopus 로고
    • The pathophysiology of the collateral circulation (arteriogenesis)
    • Buschmann, I., and Schaper, W. (2000). The pathophysiology of the collateral circulation (arteriogenesis). J. Pathol. 190, 338-342. doi: 10.1002/(SICI)1096-9896(200002)190:3<338::AID-PATH594>3.0.CO;2-7
    • (2000) J. Pathol , vol.190 , pp. 338-342
    • Buschmann, I.1    Schaper, W.2
  • 6
    • 0025829752 scopus 로고
    • In vitro and in vivo activation of endothelial cells by colony-stimulating factors
    • Bussolino, F., Ziche, M., Wang, J. M., Alessi, D., Morbidelli, L., Cremona, O., et al. (1991). In vitro and in vivo activation of endothelial cells by colony-stimulating factors. J. Clin. Invest. 87, 986-995. doi: 10.1172/JCI115107
    • (1991) J. Clin. Invest , vol.87 , pp. 986-995
    • Bussolino, F.1    Ziche, M.2    Wang, J.M.3    Alessi, D.4    Morbidelli, L.5    Cremona, O.6
  • 7
    • 42549085246 scopus 로고    scopus 로고
    • Pilot study of granulocyte colony stimulating factor (G-CSF)-mobilized peripheral blood stem cells in amyotrophic lateral sclerosis (ALS)
    • Cashman, N., Tan, L. Y., Krieger, C., Mädler, B., Mackay, A., Mackenzie, I., et al. (2008). Pilot study of granulocyte colony stimulating factor (G-CSF)-mobilized peripheral blood stem cells in amyotrophic lateral sclerosis (ALS). Muscle Nerve 37, 620-625. doi: 10.1002/mus.20951
    • (2008) Muscle Nerve , vol.37 , pp. 620-625
    • Cashman, N.1    Tan, L.Y.2    Krieger, C.3    Mädler, B.4    Mackay, A.5    Mackenzie, I.6
  • 8
    • 85062200745 scopus 로고    scopus 로고
    • Increasing de novo neurogenesis for the therapy of motor neuron degeneration in ALS-like mice
    • Chi, L., Chun, L., and Rugao, L. (2006a). Increasing de novo neurogenesis for the therapy of motor neuron degeneration in ALS-like mice. Acta Pharmacol. Sin. 27, 430-430
    • (2006) Acta Pharmacol. Sin , vol.27 , pp. 430-430
    • Chi, L.1    Chun, L.2    Rugao, L.3
  • 9
    • 34548500097 scopus 로고    scopus 로고
    • Temporal response of neural progenitor cells to disease onset and progression in amyotrophic lateral sclerosis-like transgenic mice
    • Chi, L., Gan, L., Luo, C., Lien, L., and Liu, R. (2007). Temporal response of neural progenitor cells to disease onset and progression in amyotrophic lateral sclerosis-like transgenic mice. Stem Cells Dev. 16, 579-588. doi: 10.1089/scd.2006.0120
    • (2007) Stem Cells Dev , vol.16 , pp. 579-588
    • Chi, L.1    Gan, L.2    Luo, C.3    Lien, L.4    Liu, R.5
  • 10
    • 33645533489 scopus 로고    scopus 로고
    • Motor neuron degeneration promotes neural progenitor cell proliferation, migration, and neurogenesis in the spinal cords of amyotrophic lateral sclerosis mice
    • Chi, L., Ke, Y., Luo, C., Li, B., Gozal, D., Kalyanaraman, B., et al. (2006b). Motor neuron degeneration promotes neural progenitor cell proliferation, migration, and neurogenesis in the spinal cords of amyotrophic lateral sclerosis mice. Stem Cells 24, 34-43. doi: 10.1634/stemcells.2005-0076
    • (2006) Stem Cells , vol.24 , pp. 34-43
    • Chi, L.1    Ke, Y.2    Luo, C.3    Li, B.4    Gozal, D.5    Kalyanaraman, B.6
  • 11
    • 78751665486 scopus 로고    scopus 로고
    • Repeated courses of granulocyte colony-stimulating factor in amyotrophic lateral sclerosis: clinical and biological results from a prospective multicenter study
    • Chiò, A., Mora, G., La Bella, V., Caponnetto, C., Mancardi, G., Sabatelli, M., et al. (2011). Repeated courses of granulocyte colony-stimulating factor in amyotrophic lateral sclerosis: clinical and biological results from a prospective multicenter study. Muscle Nerve 43, 189-195. doi: 10.1002/mus.21851
    • (2011) Muscle Nerve , vol.43 , pp. 189-195
    • Chiò, A.1    Mora, G.2    La Bella, V.3    Caponnetto, C.4    Mancardi, G.5    Sabatelli, M.6
  • 12
    • 84925225005 scopus 로고    scopus 로고
    • Effects of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor on glial scar formation after spinal cord injury in rats
    • Chung, J., Kim, M. H., Yoon, Y. J., Kim, K. H., Park, S. R., and Choi, B. H. (2014). Effects of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor on glial scar formation after spinal cord injury in rats. J. Neurosurg. Spine 21, 966-973. doi: 10.3171/2014.8.SPINE131090
    • (2014) J. Neurosurg. Spine , vol.21 , pp. 966-973
    • Chung, J.1    Kim, M.H.2    Yoon, Y.J.3    Kim, K.H.4    Park, S.R.5    Choi, B.H.6
  • 13
    • 35448983646 scopus 로고    scopus 로고
    • Characterization of human angiogenin variants implicated in amyotrophic lateral sclerosis
    • Crabtree, B., Thiyagarajan, N., Prior, S. H., Wilson, P., Iyer, S., Ferns, T., et al. (2007). Characterization of human angiogenin variants implicated in amyotrophic lateral sclerosis. Biochemistry 46, 11810-11818. doi: 10.1021/bi701333h
    • (2007) Biochemistry , vol.46 , pp. 11810-11818
    • Crabtree, B.1    Thiyagarajan, N.2    Prior, S.H.3    Wilson, P.4    Iyer, S.5    Ferns, T.6
  • 14
    • 33646538730 scopus 로고    scopus 로고
    • G-CSF administration after myocardial infarction in mice attenuates late ischemic cardiomyopathy by enhanced arteriogenesis
    • Deindl, E., Zaruba, M. M., Brunner, S., Huber, B., Mehl, U., Assmann, G., et al. (2006). G-CSF administration after myocardial infarction in mice attenuates late ischemic cardiomyopathy by enhanced arteriogenesis. FASEB J. 20, 956-958. doi: 10.1096/fj.05-4763fje
    • (2006) FASEB J , vol.20 , pp. 956-958
    • Deindl, E.1    Zaruba, M.M.2    Brunner, S.3    Huber, B.4    Mehl, U.5    Assmann, G.6
  • 15
    • 84922337342 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor attenuates delayed tPA-induced hemorrhagic transformation in ischemic stroke rats by enhancing angiogenesis and vasculogenesis
    • Dela Peña, I. C., Yoo, A., Tajiri, N., Acosta, S. A., Ji, X., Kaneko, Y., et al. (2015). Granulocyte colony-stimulating factor attenuates delayed tPA-induced hemorrhagic transformation in ischemic stroke rats by enhancing angiogenesis and vasculogenesis. J. Cereb. Blood Flow Metab. 35, 338-346. doi: 10.1038/jcbfm.2014.208
    • (2015) J. Cereb. Blood Flow Metab , vol.35 , pp. 338-346
    • Dela Peña, I.C.1    Yoo, A.2    Tajiri, N.3    Acosta, S.A.4    Ji, X.5    Kaneko, Y.6
  • 16
    • 84890341113 scopus 로고    scopus 로고
    • Safety of granulocyte colony-stimulating factor (G-CSF) administration for postrehabilitated motor complete spinal cord injury patients: an open-label, phase I study
    • Derakhshanrad, N., Saberi, H., Yekaninejad, M. S., Eskandari, G., Mardani, A., Rahdari, F., et al. (2013). Safety of granulocyte colony-stimulating factor (G-CSF) administration for postrehabilitated motor complete spinal cord injury patients: an open-label, phase I study. Cell Transplant. 22(Suppl. 1), S139-S146. doi: 10.3727/096368913X672109
    • (2013) Cell Transplant , vol.22 , pp. S139-S146
    • Derakhshanrad, N.1    Saberi, H.2    Yekaninejad, M.S.3    Eskandari, G.4    Mardani, A.5    Rahdari, F.6
  • 17
    • 84878822765 scopus 로고    scopus 로고
    • Adult hippocampal neurogenesis reduces memory interference in humans: opposing effects of aerobic exercise and depression
    • Déry, N., Pilgrim, M., Gibala, M., Gillen, J., Wojtowicz, J. M., Macqueen, G., et al. (2013). Adult hippocampal neurogenesis reduces memory interference in humans: opposing effects of aerobic exercise and depression. Front. Neurosci. 7:66. doi: 10.3389/fnins.2013.00066
    • (2013) Front. Neurosci , vol.7 , pp. 66
    • Déry, N.1    Pilgrim, M.2    Gibala, M.3    Gillen, J.4    Wojtowicz, J.M.5    Macqueen, G.6
  • 18
    • 84859710791 scopus 로고    scopus 로고
    • Seeing old friends from a different angle: novel properties of hematopoietic growth factors in the healthy and diseased brain
    • Diederich, K., Schäbitz, W. R., and Minnerup, J. (2012). Seeing old friends from a different angle: novel properties of hematopoietic growth factors in the healthy and diseased brain. Hippocampus 22, 1051-1057. doi: 10.1002/hipo.20904
    • (2012) Hippocampus , vol.22 , pp. 1051-1057
    • Diederich, K.1    Schäbitz, W.R.2    Minnerup, J.3
  • 19
    • 70349089732 scopus 로고    scopus 로고
    • The role of granulocyte-colony stimulating factor (G-CSF) in the healthy brain: a characterization of G-CSF-deficient mice
    • Diederich, K., Sevimli, S., Dörr, H., Kösters, E., Hoppen, M., Lewejohann, L., et al. (2009). The role of granulocyte-colony stimulating factor (G-CSF) in the healthy brain: a characterization of G-CSF-deficient mice. J. Neurosci. 29, 11572-11581. doi: 10.1523/JNEUROSCI.0453-09.2009
    • (2009) J. Neurosci , vol.29 , pp. 11572-11581
    • Diederich, K.1    Sevimli, S.2    Dörr, H.3    Kösters, E.4    Hoppen, M.5    Lewejohann, L.6
  • 20
    • 84855805319 scopus 로고    scopus 로고
    • Granulocyte-colony stimulating factor (G-CSF) improves motor recovery in the rat impactor model for spinal cord injury
    • Dittgen, T., Pitzer, C., Plaas, C., Kirsch, F., Vogt, G., Laage, R., et al. (2012). Granulocyte-colony stimulating factor (G-CSF) improves motor recovery in the rat impactor model for spinal cord injury. PLoS ONE 7:e29880. doi: 10.1371/journal.pone.0029880
    • (2012) PLoS ONE , vol.7
    • Dittgen, T.1    Pitzer, C.2    Plaas, C.3    Kirsch, F.4    Vogt, G.5    Laage, R.6
  • 21
    • 84857484642 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor improves cerebrovascular reserve capacity by enhancing collateral growth in the circle of Willis
    • Duelsner, A., Gatzke, N., Glaser, J., Hillmeister, P., Li, M., Lee, E. J., et al. (2012). Granulocyte colony-stimulating factor improves cerebrovascular reserve capacity by enhancing collateral growth in the circle of Willis. Cerebrovasc. Dis. 33, 419-429. doi: 10.1159/000335869
    • (2012) Cerebrovasc. Dis , vol.33 , pp. 419-429
    • Duelsner, A.1    Gatzke, N.2    Glaser, J.3    Hillmeister, P.4    Li, M.5    Lee, E.J.6
  • 22
    • 79952680419 scopus 로고    scopus 로고
    • G-CSF prevents the progression of structural disintegration of white matter tracts in amyotrophic lateral sclerosis: a pilot trial
    • Duning, T., Schiffbauer, H., Warnecke, T., Mohammadi, S., Floel, A., Kolpatzik, K., et al. (2011). G-CSF prevents the progression of structural disintegration of white matter tracts in amyotrophic lateral sclerosis: a pilot trial. PLoS ONE 6:e17770. doi: 10.1371/journal.pone.0017770
    • (2011) PLoS ONE , vol.6
    • Duning, T.1    Schiffbauer, H.2    Warnecke, T.3    Mohammadi, S.4    Floel, A.5    Kolpatzik, K.6
  • 23
    • 47549106881 scopus 로고    scopus 로고
    • Mechanisms of action of angiogenin
    • Gao, X., and Xu, Z. (2008). Mechanisms of action of angiogenin. Acta Biochim. Biophys. Sin. (Shanghai) 40, 619-624. doi: 10.1111/j.1745-7270.2008.00442.x
    • (2008) Acta Biochim. Biophys. Sin. (Shanghai) , vol.40 , pp. 619-624
    • Gao, X.1    Xu, Z.2
  • 24
    • 84894527844 scopus 로고    scopus 로고
    • Safety and feasibility of long term administration of recombinant human granulocyte-colony stimulating factor in patients with amyotrophic lateral sclerosis
    • Grassinger, J., Khomenko, A., Hart, C., Baldaranov, D., Johannesen, S. W., Mueller, G., et al. (2014). Safety and feasibility of long term administration of recombinant human granulocyte-colony stimulating factor in patients with amyotrophic lateral sclerosis. Cytokine 67, 21-28. doi: 10.1016/j.cyto.2014.02.003
    • (2014) Cytokine , vol.67 , pp. 21-28
    • Grassinger, J.1    Khomenko, A.2    Hart, C.3    Baldaranov, D.4    Johannesen, S.W.5    Mueller, G.6
  • 25
    • 84874963796 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor improves alternative activation of microglia under microenvironment of spinal cord injury
    • Guo, Y., Zhang, H., Yang, J., Liu, S., Bing, L., Gao, J., et al. (2013). Granulocyte colony-stimulating factor improves alternative activation of microglia under microenvironment of spinal cord injury. Neuroscience 238, 1-10. doi: 10.1016/j.neuroscience.2013.01.047
    • (2013) Neuroscience , vol.238 , pp. 1-10
    • Guo, Y.1    Zhang, H.2    Yang, J.3    Liu, S.4    Bing, L.5    Gao, J.6
  • 26
    • 80855123608 scopus 로고    scopus 로고
    • Depression, antidepressants, and neurogenesis: a critical reappraisal
    • Hanson, N. D., Owens, M. J., and Nemeroff, C. B. (2011). Depression, antidepressants, and neurogenesis: a critical reappraisal. Neuropsychopharmacology 36, 2589-2602. doi: 10.1038/npp.2011.220
    • (2011) Neuropsychopharmacology , vol.36 , pp. 2589-2602
    • Hanson, N.D.1    Owens, M.J.2    Nemeroff, C.B.3
  • 27
    • 33748366975 scopus 로고    scopus 로고
    • Arteriogenesis versus angiogenesis: similarities and differences
    • Heil, M., Eitenmuller, I., Schmitz-Rixen, T., and Schaper, W. (2006). Arteriogenesis versus angiogenesis: similarities and differences. J. Cell. Mol. Med. 10, 45-55. doi: 10.1111/j.1582-4934.2006.tb00290.x
    • (2006) J. Cell. Mol. Med , vol.10 , pp. 45-55
    • Heil, M.1    Eitenmuller, I.2    Schmitz-Rixen, T.3    Schaper, W.4
  • 28
    • 84921875307 scopus 로고    scopus 로고
    • Gene expression changes in spinal motoneurons of the SOD1(G93A) transgenic model for ALS after treatment with G-CSF
    • Henriques, A., Kastner, S., Chatzikonstantinou, E., Pitzer, C., Plaas, C., Kirsch, F., et al. (2014). Gene expression changes in spinal motoneurons of the SOD1(G93A) transgenic model for ALS after treatment with G-CSF. Front. Cell. Neurosci. 8:464. doi: 10.3389/fncel.2014.00464
    • (2014) Front. Cell. Neurosci , vol.8 , pp. 464
    • Henriques, A.1    Kastner, S.2    Chatzikonstantinou, E.3    Pitzer, C.4    Plaas, C.5    Kirsch, F.6
  • 29
    • 79551631827 scopus 로고    scopus 로고
    • CNS-targeted viral delivery of G-CSF in an animal model for ALS: improved efficacy and preservation of the neuromuscular unit
    • Henriques, A., Pitzer, C., Dittgen, T., Klugmann, M., Dupuis, L., and Schneider, A. (2011). CNS-targeted viral delivery of G-CSF in an animal model for ALS: improved efficacy and preservation of the neuromuscular unit. Mol. Ther. 19, 284-292. doi: 10.1038/mt.2010.271
    • (2011) Mol. Ther , vol.19 , pp. 284-292
    • Henriques, A.1    Pitzer, C.2    Dittgen, T.3    Klugmann, M.4    Dupuis, L.5    Schneider, A.6
  • 30
    • 78649723621 scopus 로고    scopus 로고
    • Neurotrophic growth factors for the treatment of amyotrophic lateral sclerosis: where do we stand?
    • Henriques, A., Pitzer, C., and Schneider, A. (2010). Neurotrophic growth factors for the treatment of amyotrophic lateral sclerosis: where do we stand? Front. Neurosci. 4:32. doi: 10.3389/fnins.2010.00032
    • (2010) Front. Neurosci , vol.4 , pp. 32
    • Henriques, A.1    Pitzer, C.2    Schneider, A.3
  • 31
    • 84905498655 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor therapy for stem cell mobilization following anterior wall myocardial infarction: the CAPITAL STEM MI randomized trial
    • Hibbert, B., Hayley, B., Beanlands, R. S., Le May, M., Davies, R., So, D., et al. (2014). Granulocyte colony-stimulating factor therapy for stem cell mobilization following anterior wall myocardial infarction: the CAPITAL STEM MI randomized trial. CMAJ 186, E427-E434. doi: 10.1503/cmaj.140133
    • (2014) CMAJ , vol.186 , pp. E427-E434
    • Hibbert, B.1    Hayley, B.2    Beanlands, R.S.3    Le May, M.4    Davies, R.5    So, D.6
  • 32
    • 84894053275 scopus 로고    scopus 로고
    • Multicenter prospective nonrandomized controlled clinical trial to prove neurotherapeutic effects of granulocyte colony-stimulating factor for acute spinal cord injury: analyses of follow-up cases after at least 1 yea
    • Inada, T., Takahashi, H., Yamazaki, M., Okawa, A., Sakuma, T., Kato, K., et al. (2014). Multicenter prospective nonrandomized controlled clinical trial to prove neurotherapeutic effects of granulocyte colony-stimulating factor for acute spinal cord injury: analyses of follow-up cases after at least 1 year. Spine (Phila Pa 1976) 39, 213-219. doi: 10.1097/BRS.0000000000000121
    • (2014) Spine (Phila Pa 1976) , vol.39 , pp. 213-219
    • Inada, T.1    Takahashi, H.2    Yamazaki, M.3    Okawa, A.4    Sakuma, T.5    Kato, K.6
  • 33
    • 84923111823 scopus 로고    scopus 로고
    • Risk factors for amyotrophic lateral sclerosis
    • Ingre, C., Roos, P. M., Piehl, F., Kamel, F., and Fang, F. (2015). Risk factors for amyotrophic lateral sclerosis. Clin. Epidemiol. 7, 181-193. doi: 10.2147/CLEP.S37505
    • (2015) Clin. Epidemiol , vol.7 , pp. 181-193
    • Ingre, C.1    Roos, P.M.2    Piehl, F.3    Kamel, F.4    Fang, F.5
  • 34
    • 0000481740 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischemia
    • Jin, K. L., Mao, X. O., and Greenberg, D. A. (2000a). Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischemia. Proc. Natl. Acad. Sci. U.S.A. 97, 10242-10247. doi: 10.1073/pnas.97.18.10242
    • (2000) Proc. Natl. Acad. Sci. U.S.A , vol.97 , pp. 10242-10247
    • Jin, K.L.1    Mao, X.O.2    Greenberg, D.A.3
  • 35
    • 0034675037 scopus 로고    scopus 로고
    • Induction of vascular endothelial growth factor and hypoxia-inducible factor-1alpha by global ischemia in rat brain
    • Jin, K. L., Mao, X. O., Nagayama, T., Goldsmith, P. C., and Greenberg, D. A. (2000b). Induction of vascular endothelial growth factor and hypoxia-inducible factor-1alpha by global ischemia in rat brain. Neuroscience 99, 577-585. doi: 10.1016/S0306-4522(00)00207-4
    • (2000) Neuroscience , vol.99 , pp. 577-585
    • Jin, K.L.1    Mao, X.O.2    Nagayama, T.3    Goldsmith, P.C.4    Greenberg, D.A.5
  • 36
    • 84870287319 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor (G-CSF) protects oligodendrocyte and promotes hindlimb functional recovery after spinal cord injury in rats
    • Kadota, R., Koda, M., Kawabe, J., Hashimoto, M., Nishio, Y., Mannoji, C., et al. (2012). Granulocyte colony-stimulating factor (G-CSF) protects oligodendrocyte and promotes hindlimb functional recovery after spinal cord injury in rats. PLoS ONE 7:e50391. doi: 10.1371/journal.pone.0050391
    • (2012) PLoS ONE , vol.7
    • Kadota, R.1    Koda, M.2    Kawabe, J.3    Hashimoto, M.4    Nishio, Y.5    Mannoji, C.6
  • 37
    • 80053443043 scopus 로고    scopus 로고
    • Neuroprotective effects of granulocyte colony-stimulating factor and relationship to promotion of angiogenesis after spinal cord injury in rats: laboratory investigation
    • Kawabe, J., Koda, M., Hashimoto, M., Fujiyoshi, T., Furuya, T., Endo, T., et al. (2011). Neuroprotective effects of granulocyte colony-stimulating factor and relationship to promotion of angiogenesis after spinal cord injury in rats: laboratory investigation. J. Neurosurg. Spine 15, 414-421. doi: 10.3171/2011.5.SPINE10421
    • (2011) J. Neurosurg. Spine , vol.15 , pp. 414-421
    • Kawabe, J.1    Koda, M.2    Hashimoto, M.3    Fujiyoshi, T.4    Furuya, T.5    Endo, T.6
  • 39
    • 42549091223 scopus 로고    scopus 로고
    • The receptor for granulocyte-colony stimulating factor (G-CSF) is expressed in radial glia during development of the nervous system
    • Kirsch, F., Krüger, C., and Schneider, A. (2008). The receptor for granulocyte-colony stimulating factor (G-CSF) is expressed in radial glia during development of the nervous system. BMC Dev. Biol. 8:32. doi: 10.1186/1471-213X-8-32
    • (2008) BMC Dev. Biol , vol.8 , pp. 32
    • Kirsch, F.1    Krüger, C.2    Schneider, A.3
  • 40
    • 34247521004 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor (G-CSF) mobilizes bone marrow-derived cells into injured spinal cord and promotes functional recovery after compression-induced spinal cord injury in mice
    • Koda, M., Nishio, Y., Kamada, T., Someya, Y., Okawa, A., Mori, C., et al. (2007). Granulocyte colony-stimulating factor (G-CSF) mobilizes bone marrow-derived cells into injured spinal cord and promotes functional recovery after compression-induced spinal cord injury in mice. Brain Res. 1149, 223-231. doi: 10.1016/j.brainres.2007.02.058
    • (2007) Brain Res , vol.1149 , pp. 223-231
    • Koda, M.1    Nishio, Y.2    Kamada, T.3    Someya, Y.4    Okawa, A.5    Mori, C.6
  • 41
    • 31344466983 scopus 로고    scopus 로고
    • G-CSF/SCF reduces inducible arrhythmias in the infarcted heart potentially via increased connexin43 expression and arteriogenesis
    • Kuhlmann, M. T., Kirchhof, P., Klocke, R., Hasib, L., Stypmann, J., Fabritz, L., et al. (2006). G-CSF/SCF reduces inducible arrhythmias in the infarcted heart potentially via increased connexin43 expression and arteriogenesis. J. Exp. Med. 203, 87-97. doi: 10.1084/jem.20051151
    • (2006) J. Exp. Med , vol.203 , pp. 87-97
    • Kuhlmann, M.T.1    Kirchhof, P.2    Klocke, R.3    Hasib, L.4    Stypmann, J.5    Fabritz, L.6
  • 42
    • 0041903805 scopus 로고    scopus 로고
    • VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death
    • Lambrechts, D., Storkebaum, E., Morimoto, M., Del-Favero, J., Desmet, F., Marklund, S. L., et al. (2003). VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death. Nat. Genet. 34, 383-394. doi: 10.1038/ng1211
    • (2003) Nat. Genet , vol.34 , pp. 383-394
    • Lambrechts, D.1    Storkebaum, E.2    Morimoto, M.3    Del-Favero, J.4    Desmet, F.5    Marklund, S.L.6
  • 43
    • 26244442250 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor enhances angiogenesis after focal cerebral ischemia
    • Lee, S. T., Chu, K., Jung, K. H., Ko, S. Y., Kim, E. H., Sinn, D. I., et al. (2005). Granulocyte colony-stimulating factor enhances angiogenesis after focal cerebral ischemia. Brain Res. 1058, 120-128. doi: 10.1016/j.brainres.2005.07.076
    • (2005) Brain Res , vol.1058 , pp. 120-128
    • Lee, S.T.1    Chu, K.2    Jung, K.H.3    Ko, S.Y.4    Kim, E.H.5    Sinn, D.I.6
  • 44
  • 45
    • 84869742367 scopus 로고    scopus 로고
    • Stem cell transplantation in amyotrophic lateral sclerosis patients: methodological approach, safety, and feasibility
    • Martínez, H. R., Molina-Lopez, J. F., González-Garza, M. T., Moreno-Cuevas, J. E., Caro-Osorio, E., Gil-Valadez, A., et al. (2012). Stem cell transplantation in amyotrophic lateral sclerosis patients: methodological approach, safety, and feasibility. Cell Transplant. 21, 1899-1907. doi: 10.3727/096368911X582769
    • (2012) Cell Transplant , vol.21 , pp. 1899-1907
    • Martínez, H.R.1    Molina-Lopez, J.F.2    González-Garza, M.T.3    Moreno-Cuevas, J.E.4    Caro-Osorio, E.5    Gil-Valadez, A.6
  • 46
    • 34250208597 scopus 로고    scopus 로고
    • Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND)
    • Miller, R. G., Mitchell, J. D., and Moore, D. H. (2012). Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND). Cochrane Database Syst. Rev. 3:CD001447. doi: 10.1002/14651858.CD001447.pub3
    • (2012) Cochrane Database Syst. Rev , vol.3
    • Miller, R.G.1    Mitchell, J.D.2    Moore, D.H.3
  • 47
    • 84859228716 scopus 로고    scopus 로고
    • Gender-specific mechanism of synaptic impairment and its prevention by GCSF in a mouse model of ALS
    • Naumenko, N., Pollari, E., Kurronen, A., Giniatullina, R., Shakirzyanova, A., Magga, J., et al. (2011). Gender-specific mechanism of synaptic impairment and its prevention by GCSF in a mouse model of ALS. Front. Cell. Neurosci. 5:26. doi: 10.3389/fncel.2011.00026
    • (2011) Front. Cell. Neurosci , vol.5 , pp. 26
    • Naumenko, N.1    Pollari, E.2    Kurronen, A.3    Giniatullina, R.4    Shakirzyanova, A.5    Magga, J.6
  • 48
    • 77649323766 scopus 로고    scopus 로고
    • Recombinant human granulocyte-colony stimulating factor administration for treating amyotrophic lateral sclerosis: a pilot study
    • Nefussy, B., Artamonov, I., Deutsch, V., Naparstek, E., Nagler, A., and Drory, V. E. (2010). Recombinant human granulocyte-colony stimulating factor administration for treating amyotrophic lateral sclerosis: a pilot study. Amyotroph. Lateral Scler. 11, 187-193. doi: 10.3109/17482960902933809
    • (2010) Amyotroph. Lateral Scler , vol.11 , pp. 187-193
    • Nefussy, B.1    Artamonov, I.2    Deutsch, V.3    Naparstek, E.4    Nagler, A.5    Drory, V.E.6
  • 49
    • 0020960887 scopus 로고
    • Purification of a factor inducing differentiation in murine myelomonocytic leukemia cells Identification as granulocyte colony-stimulating factor
    • Nicola, N. A., Metcalf, D., Matsumoto, M., and Johnson, G. R. (1983). Purification of a factor inducing differentiation in murine myelomonocytic leukemia cells. Identification as granulocyte colony-stimulating factor. J. Biol. Chem. 258, 9017-9023
    • (1983) J. Biol. Chem , vol.258 , pp. 9017-9023
    • Nicola, N.A.1    Metcalf, D.2    Matsumoto, M.3    Johnson, G.R.4
  • 50
    • 34548297819 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor attenuates neuronal death and promotes functional recovery after spinal cord injury in mice
    • Nishio, Y., Koda, M., Kamada, T., Someya, Y., Kadota, R., Mannoji, C., et al. (2007). Granulocyte colony-stimulating factor attenuates neuronal death and promotes functional recovery after spinal cord injury in mice. J. Neuropathol. Exp. Neurol. 66, 724-731. doi: 10.1097/nen.0b013e3181257176
    • (2007) J. Neuropathol. Exp. Neurol , vol.66 , pp. 724-731
    • Nishio, Y.1    Koda, M.2    Kamada, T.3    Someya, Y.4    Kadota, R.5    Mannoji, C.6
  • 51
    • 28744438835 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor promotes neovascularization by releasing vascular endothelial growth factor from neutrophils
    • Ohki, Y., Heissig, B., Sato, Y., Akiyama, H., Zhu, Z., Hicklin, D. J., et al. (2005). Granulocyte colony-stimulating factor promotes neovascularization by releasing vascular endothelial growth factor from neutrophils. FASEB J. 19, 2005-2007. doi: 10.1096/fj.04-3496fje
    • (2005) FASEB J , vol.19 , pp. 2005-2007
    • Ohki, Y.1    Heissig, B.2    Sato, Y.3    Akiyama, H.4    Zhu, Z.5    Hicklin, D.J.6
  • 52
    • 0034978562 scopus 로고    scopus 로고
    • Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration
    • Oosthuyse, B., Moons, L., Storkebaum, E., Beck, H., Nuyens, D., Brusselmans, K., et al. (2001). Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration. Nat. Genet. 28, 131-138. doi: 10.1038/88842
    • (2001) Nat. Genet , vol.28 , pp. 131-138
    • Oosthuyse, B.1    Moons, L.2    Storkebaum, E.3    Beck, H.4    Nuyens, D.5    Brusselmans, K.6
  • 53
    • 77957943588 scopus 로고    scopus 로고
    • Efficacy of the coadministration of granulocyte colony-stimulating factor and stem cell factor in the activation of intrinsic cells after spinal cord injury in mice
    • Osada, T., Watanabe, M., Hasuo, A., Imai, M., Suyama, K., Sakai, D., et al. (2010). Efficacy of the coadministration of granulocyte colony-stimulating factor and stem cell factor in the activation of intrinsic cells after spinal cord injury in mice. J. Neurosurg. Spine 13, 516-523. doi: 10.3171/2010.4.SPINE09973
    • (2010) J. Neurosurg. Spine , vol.13 , pp. 516-523
    • Osada, T.1    Watanabe, M.2    Hasuo, A.3    Imai, M.4    Suyama, K.5    Sakai, D.6
  • 54
    • 84862770601 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms underlying the role of blood vessels in spinal cord injury and repair
    • Oudega, M. (2012). Molecular and cellular mechanisms underlying the role of blood vessels in spinal cord injury and repair. Cell Tissue Res. 349, 269-288. doi: 10.1007/s00441-012-1440-6
    • (2012) Cell Tissue Res , vol.349 , pp. 269-288
    • Oudega, M.1
  • 55
    • 43049170332 scopus 로고    scopus 로고
    • Enhanced regeneration in spinal cord injury by concomitant treatment with granulocyte colony-stimulating factor and neuronal stem cells
    • Pan, H. C., Cheng, F. C., Lai, S. Z., Yang, D. Y., Wang, Y. C., and Lee, M. S. (2008). Enhanced regeneration in spinal cord injury by concomitant treatment with granulocyte colony-stimulating factor and neuronal stem cells. J. Clin. Neurosci. 15, 656-664. doi: 10.1016/j.jocn.2007.03.020
    • (2008) J. Clin. Neurosci , vol.15 , pp. 656-664
    • Pan, H.C.1    Cheng, F.C.2    Lai, S.Z.3    Yang, D.Y.4    Wang, Y.C.5    Lee, M.S.6
  • 56
    • 77950919896 scopus 로고    scopus 로고
    • The hematopoietic factor granulocyte-colony stimulating factor improves outcome in experimental spinal cord injury
    • Pitzer, C., Klussmann, S., Kruger, C., Letellier, E., Plaas, C., Dittgen, T., et al. (2010). The hematopoietic factor granulocyte-colony stimulating factor improves outcome in experimental spinal cord injury. J. Neurochem. 113, 930-942. doi: 10.1111/j.1471-4159.2010.06659.x
    • (2010) J. Neurochem , vol.113 , pp. 930-942
    • Pitzer, C.1    Klussmann, S.2    Kruger, C.3    Letellier, E.4    Plaas, C.5    Dittgen, T.6
  • 57
    • 58149119552 scopus 로고    scopus 로고
    • Granulocyte-colony stimulating factor improves outcome in a mouse model of amyotrophic lateral sclerosis
    • Pitzer, C., Krüger, C., Plaas, C., Kirsch, F., Dittgen, T., Muller, R., et al. (2008). Granulocyte-colony stimulating factor improves outcome in a mouse model of amyotrophic lateral sclerosis. Brain 131, 3335-3347. doi: 10.1093/brain/awn243
    • (2008) Brain , vol.131 , pp. 3335-3347
    • Pitzer, C.1    Krüger, C.2    Plaas, C.3    Kirsch, F.4    Dittgen, T.5    Muller, R.6
  • 58
    • 79959618231 scopus 로고    scopus 로고
    • Granulocyte colony stimulating factor attenuates inflammation in a mouse model of amyotrophic lateral sclerosis
    • Pollari, E., Savchenko, E., Jaronen, M., Kanninen, K., Malm, T., Wojciechowski, S., et al. (2011). Granulocyte colony stimulating factor attenuates inflammation in a mouse model of amyotrophic lateral sclerosis. J. Neuroinflammation 8:74. doi: 10.1186/1742-2094-8-74
    • (2011) J. Neuroinflammation , vol.8 , pp. 74
    • Pollari, E.1    Savchenko, E.2    Jaronen, M.3    Kanninen, K.4    Malm, T.5    Wojciechowski, S.6
  • 59
    • 84901312256 scopus 로고    scopus 로고
    • Roles of vascular endothelial growth factor in amyotrophic lateral sclerosis
    • Pronto-Laborinho, A. C., Pinto, S., and de Carvalho, M. (2014). Roles of vascular endothelial growth factor in amyotrophic lateral sclerosis. Biomed Res. Int. 2014:947513. doi: 10.1155/2014/947513
    • (2014) Biomed Res. Int , vol.2014
    • Pronto-Laborinho, A.C.1    Pinto, S.2    de Carvalho, M.3
  • 60
    • 84908378496 scopus 로고    scopus 로고
    • Neural stem cells in the adult spinal cord
    • Sabelström, H., Stenudd, M., and Frisen, J. (2014). Neural stem cells in the adult spinal cord. Exp. Neurol. 260, 44-49. doi: 10.1016/j.expneurol.2013.01.026
    • (2014) Exp. Neurol , vol.260 , pp. 44-49
    • Sabelström, H.1    Stenudd, M.2    Frisen, J.3
  • 61
    • 84947547635 scopus 로고    scopus 로고
    • Comparison of neurological and functional outcomes after administration of granulocyte-colony-stimulating factor in motor-complete versus motor-incomplete postrehabilitated, chronic spinal cord injuries: a phase I/II study
    • Saberi, H., Derakhshanrad, N., and Yekaninejad, M. S. (2014). Comparison of neurological and functional outcomes after administration of granulocyte-colony-stimulating factor in motor-complete versus motor-incomplete postrehabilitated, chronic spinal cord injuries: a phase I/II study. Cell Transplant. 23(Suppl. 1), S19-S23. doi: 10.3727/096368914X684943
    • (2014) Cell Transplant , vol.23 , pp. S19-S23
    • Saberi, H.1    Derakhshanrad, N.2    Yekaninejad, M.S.3
  • 62
    • 84862885870 scopus 로고    scopus 로고
    • Neuroprotective therapy using granulocyte colony-stimulating factor for patients with worsening symptoms of compression myelopathy, Part 1, a phase I and IIa clinical trial
    • Sakuma, T., Yamazaki, M., Okawa, A., Takahashi, H., Kato, K., Hashimoto, M., et al. (2012). Neuroprotective therapy using granulocyte colony-stimulating factor for patients with worsening symptoms of compression myelopathy, Part 1: a phase I and IIa clinical trial. Eur. Spine J. 21, 482-489. doi: 10.1007/s00586-011-2020-2
    • (2012) Eur. Spine J , vol.21 , pp. 482-489
    • Sakuma, T.1    Yamazaki, M.2    Okawa, A.3    Takahashi, H.4    Kato, K.5    Hashimoto, M.6
  • 63
    • 78049470925 scopus 로고    scopus 로고
    • Effect of granulocyte-colony stimulating factor on spinal cord tissue after experimental contusion injury
    • Sanli, A. M., Serbes, G., Caliskan, M., Kaptanoglu, E., Sargon, M. F., Kilinc, K., et al. (2010). Effect of granulocyte-colony stimulating factor on spinal cord tissue after experimental contusion injury. J. Clin. Neurosci. 17, 1548-1552. doi: 10.1016/j.jocn.2010.03.043
    • (2010) J. Clin. Neurosci , vol.17 , pp. 1548-1552
    • Sanli, A.M.1    Serbes, G.2    Caliskan, M.3    Kaptanoglu, E.4    Sargon, M.F.5    Kilinc, K.6
  • 64
    • 0042528720 scopus 로고    scopus 로고
    • Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
    • Santarelli, L., Saxe, M., Gross, C., Surget, A., Battaglia, F., Dulawa, S., et al. (2003). Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 301, 805-809. doi: 10.1126/science.1083328
    • (2003) Science , vol.301 , pp. 805-809
    • Santarelli, L.1    Saxe, M.2    Gross, C.3    Surget, A.4    Battaglia, F.5    Dulawa, S.6
  • 65
    • 84920267379 scopus 로고    scopus 로고
    • Adjuvant granulocyte colony-stimulating factor therapy results in improved spatial learning and stimulates hippocampal neurogenesis in a mouse model of pneumococcal meningitis
    • Schmidt, A. K., Reich, A., Falkenburger, B., Schulz, J. B., Brandenburg, L. O., Ribes, S., et al. (2015). Adjuvant granulocyte colony-stimulating factor therapy results in improved spatial learning and stimulates hippocampal neurogenesis in a mouse model of pneumococcal meningitis. J. Neuropathol. Exp. Neurol. 74, 85-94. doi: 10.1097/NEN.0000000000000152
    • (2015) J. Neuropathol. Exp. Neurol , vol.74 , pp. 85-94
    • Schmidt, A.K.1    Reich, A.2    Falkenburger, B.3    Schulz, J.B.4    Brandenburg, L.O.5    Ribes, S.6
  • 66
    • 4344646431 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor-induced arteriogenesis reduces energy failure in hemodynamic stroke
    • Schneeloch, E., Mies, G., Busch, H. J., Buschmann, I. R., and Hossmann, K. A. (2004). Granulocyte-macrophage colony-stimulating factor-induced arteriogenesis reduces energy failure in hemodynamic stroke. Proc. Natl. Acad. Sci. U.S.A. 101, 12730-12735. doi: 10.1073/pnas.0404880101
    • (2004) Proc. Natl. Acad. Sci. U.S.A , vol.101 , pp. 12730-12735
    • Schneeloch, E.1    Mies, G.2    Busch, H.J.3    Buschmann, I.R.4    Hossmann, K.A.5
  • 67
    • 23644445498 scopus 로고    scopus 로고
    • The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis
    • Schneider, A., Kruger, C., Steigleder, T., Weber, D., Pitzer, C., Laage, R., et al. (2005a). The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis. J. Clin. Invest. 115, 2083-2098. doi: 10.1172/JCI23559
    • (2005) J. Clin. Invest , vol.115 , pp. 2083-2098
    • Schneider, A.1    Kruger, C.2    Steigleder, T.3    Weber, D.4    Pitzer, C.5    Laage, R.6
  • 68
    • 29244489241 scopus 로고    scopus 로고
    • A role for G-CSF (granulocyte-colony stimulating factor) in the central nervous system
    • Schneider, A., Kuhn, H. G., and Schäbitz, W. R. (2005b). A role for G-CSF (granulocyte-colony stimulating factor) in the central nervous system. Cell Cycle 4, 1753-1757. doi: 10.4161/cc.4.12.2213
    • (2005) Cell Cycle , vol.4 , pp. 1753-1757
    • Schneider, A.1    Kuhn, H.G.2    Schäbitz, W.R.3
  • 69
    • 0034548865 scopus 로고    scopus 로고
    • Adult spinal cord stem cells generate neurons after transplantation in the adult dentate gyrus
    • Shihabuddin, L. S., Horner, P. J., Ray, J., and Gage, F. H. (2000). Adult spinal cord stem cells generate neurons after transplantation in the adult dentate gyrus. J. Neurosci. 20, 8727-8735
    • (2000) J. Neurosci , vol.20 , pp. 8727-8735
    • Shihabuddin, L.S.1    Horner, P.J.2    Ray, J.3    Gage, F.H.4
  • 70
    • 0032903416 scopus 로고    scopus 로고
    • Vascular, glial and neuronal effects of vascular endothelial growth factor in mesencephalic explant cultures
    • Silverman, W. F., Krum, J. M., Mani, N., and Rosenstein, J. M. (1999). Vascular, glial and neuronal effects of vascular endothelial growth factor in mesencephalic explant cultures. Neuroscience 90, 1529-1541
    • (1999) Neuroscience , vol.90 , pp. 1529-1541
    • Silverman, W.F.1    Krum, J.M.2    Mani, N.3    Rosenstein, J.M.4
  • 71
    • 85047694286 scopus 로고    scopus 로고
    • VEGF: a critical player in neurodegeneration
    • Storkebaum, E., and Carmeliet, P. (2004). VEGF: a critical player in neurodegeneration. J. Clin. Invest. 113, 14-18. doi: 10.1172/JCI20682
    • (2004) J. Clin. Invest , vol.113 , pp. 14-18
    • Storkebaum, E.1    Carmeliet, P.2
  • 72
    • 4644234505 scopus 로고    scopus 로고
    • VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection
    • Storkebaum, E., Lambrechts, D., and Carmeliet, P. (2004). VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection. Bioessays 26, 943-954. doi: 10.1002/bies.20092
    • (2004) Bioessays , vol.26 , pp. 943-954
    • Storkebaum, E.1    Lambrechts, D.2    Carmeliet, P.3
  • 73
    • 79952071275 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor enhances arteriogenesis and ameliorates cerebral damage in a mouse model of ischemic stroke
    • Sugiyama, Y., Yagita, Y., Oyama, N., Terasaki, Y., Omura-Matsuoka, E., Sasaki, T., et al. (2011). Granulocyte colony-stimulating factor enhances arteriogenesis and ameliorates cerebral damage in a mouse model of ischemic stroke. Stroke 42, 770-775. doi: 10.1161/STROKEAHA.110.597799
    • (2011) Stroke , vol.42 , pp. 770-775
    • Sugiyama, Y.1    Yagita, Y.2    Oyama, N.3    Terasaki, Y.4    Omura-Matsuoka, E.5    Sasaki, T.6
  • 74
    • 84875730225 scopus 로고    scopus 로고
    • Neuroprotective therapy using granulocyte colony-stimulating factor for acute spinal cord injury: a phase I/IIa clinical trial
    • Takahashi, H., Yamazaki, M., Okawa, A., Sakuma, T., Kato, K., Hashimoto, M., et al. (2012). Neuroprotective therapy using granulocyte colony-stimulating factor for acute spinal cord injury: a phase I/IIa clinical trial. Eur. Spine J. 21, 2580-2587. doi: 10.1007/s00586-012-2213-3
    • (2012) Eur. Spine J , vol.21 , pp. 2580-2587
    • Takahashi, H.1    Yamazaki, M.2    Okawa, A.3    Sakuma, T.4    Kato, K.5    Hashimoto, M.6
  • 75
    • 33846187092 scopus 로고    scopus 로고
    • Transplantation of bone marrow stem cells as well as mobilization by granulocyte-colony stimulating factor promotes recovery after spinal cord injury in rats
    • Urdzíková, L., Jendelová, P., Glogarová, K., Burian, M., Hájek, M., and Syková, E. (2006). Transplantation of bone marrow stem cells as well as mobilization by granulocyte-colony stimulating factor promotes recovery after spinal cord injury in rats. J. Neurotrauma 23, 1379-1391. doi: 10.1089/neu.2006.23.1379
    • (2006) J. Neurotrauma , vol.23 , pp. 1379-1391
    • Urdzíková, L.1    Jendelová, P.2    Glogarová, K.3    Burian, M.4    Hájek, M.5    Syková, E.6
  • 76
  • 77
    • 0035215711 scopus 로고    scopus 로고
    • Arteriogenesis: mechanisms and modulation of collateral artery development
    • Van Royen, N., Piek, J. J., Schaper, W., Bode, C., and Buschmann, I. (2001). Arteriogenesis: mechanisms and modulation of collateral artery development. J. Nucl. Cardiol. 8, 687-693. doi: 10.1067/mnc.2001.118924
    • (2001) J. Nucl. Cardiol , vol.8 , pp. 687-693
    • Van Royen, N.1    Piek, J.J.2    Schaper, W.3    Bode, C.4    Buschmann, I.5
  • 78
    • 84926512742 scopus 로고    scopus 로고
    • Adult neurogenesis in neurodegenerative diseases
    • Winner, B., and Winkler, J. (2015). Adult neurogenesis in neurodegenerative diseases. Cold Spring Harb. Perspect. Biol. 7:a021287. doi: 10.1101/cshperspect.a021287
    • (2015) Cold Spring Harb. Perspect. Biol , vol.7
    • Winner, B.1    Winkler, J.2
  • 79
    • 35248844678 scopus 로고    scopus 로고
    • Angiogenin loss-of-function mutations in amyotrophic lateral sclerosis
    • Wu, D., Yu, W., Kishikawa, H., Folkerth, R. D., Iafrate, A. J., Shen, Y., et al. (2007). Angiogenin loss-of-function mutations in amyotrophic lateral sclerosis. Ann. Neurol. 62, 609-617. doi: 10.1002/ana.21221
    • (2007) Ann. Neurol , vol.62 , pp. 609-617
    • Wu, D.1    Yu, W.2    Kishikawa, H.3    Folkerth, R.D.4    Iafrate, A.J.5    Shen, Y.6
  • 80
    • 33748358811 scopus 로고    scopus 로고
    • Incidence, prevalence and epidemiology of spinal cord injury: what learns a worldwide literature survey?
    • Wyndaele, M., and Wyndaele, J. J. (2006). Incidence, prevalence and epidemiology of spinal cord injury: what learns a worldwide literature survey? Spinal Cord 44, 523-529. doi: 10.1038/sj.sc.3101893
    • (2006) Spinal Cord , vol.44 , pp. 523-529
    • Wyndaele, M.1    Wyndaele, J.J.2
  • 81
    • 78650310477 scopus 로고    scopus 로고
    • Restoration of microglial function by granulocyte-colony stimulating factor in ALS model mice
    • Yamasaki, R., Tanaka, M., Fukunaga, M., Tateishi, T., Kikuchi, H., Motomura, K., et al. (2010). Restoration of microglial function by granulocyte-colony stimulating factor in ALS model mice. J. Neuroimmunol. 229, 51-62. doi: 10.1016/j.jneuroim.2010.07.002
    • (2010) J. Neuroimmunol , vol.229 , pp. 51-62
    • Yamasaki, R.1    Tanaka, M.2    Fukunaga, M.3    Tateishi, T.4    Kikuchi, H.5    Motomura, K.6
  • 82
    • 80052855237 scopus 로고    scopus 로고
    • Hippocampal neurogenesis and dendritic plasticity support running-improved spatial learning and depression-like behaviour in stressed rats
    • Yau, S. Y., Lau, B. W., Tong, J. B., Wong, R., Ching, Y. P., Qiu, G., et al. (2011). Hippocampal neurogenesis and dendritic plasticity support running-improved spatial learning and depression-like behaviour in stressed rats. PLoS ONE 6:e24263. doi: 10.1371/journal.pone.0024263
    • (2011) PLoS ONE , vol.6
    • Yau, S.Y.1    Lau, B.W.2    Tong, J.B.3    Wong, R.4    Ching, Y.P.5    Qiu, G.6
  • 83
    • 70450183087 scopus 로고    scopus 로고
    • Preliminary investigation of effect of granulocyte colony stimulating factor on amyotrophic lateral sclerosis
    • Zhang, Y., Wang, L., Fu, Y., Song, H., Zhao, H., Deng, M., et al. (2009). Preliminary investigation of effect of granulocyte colony stimulating factor on amyotrophic lateral sclerosis. Amyotroph. Lateral Scler. 10, 430-431. doi: 10.3109/17482960802588059
    • (2009) Amyotroph. Lateral Scler , vol.10 , pp. 430-431
    • Zhang, Y.1    Wang, L.2    Fu, Y.3    Song, H.4    Zhao, H.5    Deng, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.