G-CSF prevents the progression of structural disintegration of white matter tracts in amyotrophic lateral sclerosis: A pilot trial

PLoS ONE

Volumn 6, Issue 3, 2011, Pages

  Duning, Thomas ^a   Schiffbauer, Hagen ^a   Warnecke, Tobias ^a   Mohammadi, Siawoosh ^a   Floel, Agnes ^b   Kolpatzik, Katja ^a   Kugel, Harald ^a   Schneider, Armin ^c   Knecht, Stefan ^a   Deppe, Michael ^a   Schäbitz, Wolf Rüdiger ^a,d  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c SYGNIS Bioscience   (Germany)

^d EVK Bielefeld ^*  (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; PLACEBO; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BODY TEMPERATURE; BONE PAIN; BRAIN SIZE; CLINICAL ARTICLE; CONNECTIVE TISSUE DISEASE; CONTROLLED STUDY; DAILY LIFE ACTIVITY; DIASTOLIC BLOOD PRESSURE; DIFFUSION TENSOR IMAGING; DISEASE COURSE; DOUBLE BLIND PROCEDURE; DRUG INDUCED HEADACHE; DRUG TOLERABILITY; EXECUTIVE FUNCTION; FEASIBILITY STUDY; FEMALE; FRACTIONAL ANISOTROPY; HEART RATE; HUMAN; IMAGE ANALYSIS; INFECTION; INJECTION SITE REACTION; LEARNING; LEUKOCYTE COUNT; MALAISE; MALE; MEMORY; MUSCULOSKELETAL DISEASE; NEUROLOGIC DISEASE; NEUROPROTECTION; OUTCOME ASSESSMENT; RANDOMIZED CONTROLLED TRIAL; SKIN DISEASE; SYSTOLIC BLOOD PRESSURE; VOXEL BASED MORPHOMETRY; WHITE MATTER; BIOASSAY; BLOOD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DEMOGRAPHY; MIDDLE AGED; NEUROPSYCHOLOGICAL TEST; PATHOLOGY; PILOT STUDY;

AGED; AMYOTROPHIC LATERAL SCLEROSIS; DEMOGRAPHY; DIFFUSION TENSOR IMAGING; DISEASE PROGRESSION; ENDPOINT DETERMINATION; FEMALE; GRANULOCYTE COLONY STIMULATING FACTOR, RECOMBINANT; HUMANS; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PILOT PROJECTS;

EID: 79952680419     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0017770     Document Type: Article

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