Granulocyte colony-stimulating factor enhances arteriogenesis and ameliorates cerebral damage in a mouse model of ischemic stroke

Stroke

Volumn 42, Issue 3, 2011, Pages 770-775

  Sugiyama, Yukio ^a   Yagita, Yoshiki ^a   Oyama, Naoki ^a   Terasaki, Yasukazu ^a   Omura Matsuoka, Emi ^a   Sasaki, Tsutomu ^a   Kitagawa, Kazuo ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

animal models; arteriogenesis; brain ischemia; colony stimulating factors

Indexed keywords

BRAIN PROTEIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; PROTEIN MAC 2; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; UNCLASSIFIED DRUG;

ANASTOMOSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ARTERY; BRAIN CIRCULUS ARTERIOSUS; BRAIN DAMAGE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN PERFUSION; BRAIN PROTECTION; COLLATERAL CIRCULATION; CONTROLLED STUDY; DRUG SAFETY; LEPTOMENINX; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; UPREGULATION;

ANIMALS; BRAIN ISCHEMIA; CELL DIFFERENTIATION; CEREBRAL ARTERIES; CEREBRAL INFARCTION; COLLATERAL CIRCULATION; DISEASE MODELS, ANIMAL; GALECTIN 3; GRANULOCYTE COLONY-STIMULATING FACTOR; HUMANS; MACROPHAGE COLONY-STIMULATING FACTOR; MALE; MICE; MICE, INBRED C57BL; MONOCYTES; STROKE;

EID: 79952071275     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/STROKEAHA.110.597799     Document Type: Article

References (26)

1. Grubb RL Jr, Derdeyn CP, Fritsch SM, Carpenter DA, Yundt KD, Videen TO, Spitznagel EL, Powers WJ. Importance of hemodynamic factors in the prognosis of symptomatic carotid occlusion. JAMA. 1998;280:1055-1060. (Pubitemid 28449534)
2. Liebeskind DS. Collateral therapeutics for cerebral ischemia. Expert Rev Neurother. 2004;4:255-265. (Pubitemid 38315946)
3. Derdeyn CP, Videen TO, Fritsch SM, Carpenter DA, Grubb RL Jr, Powers WJ. Compensatory mechanisms for chronic cerebral hypoperfusion in patients with carotid occlusion. Stroke. 1999;30:1019-1024. (Pubitemid 29211621)
4. Kitagawa K, Yagita Y, Sasaki T, Sugiura S, Omura-Matsuoka E, Mabuchi T, Matsushita K, Hori M. Chronic mild reduction of cerebral perfusion pressure induces ischemic tolerance in focal cerebral ischemia. Stroke. 2005;36:2270-2274. (Pubitemid 41429258)
5. van Oostrom MC, van Oostrom O, Quax PH, Verhaar MC, Hoefer IE. Insights into mechanisms behind arteriogenesis: what does the future hold? J Leukoc Biol. 2008;84:1379-1391. (Pubitemid 352774473)
6. Kovacic JC, Muller DW, Graham RM. Actions and therapeutic potential of G-CSF and GM-CSF in cardiovascular disease. J Mol Cell Cardiol. 2007;42:19-33. (Pubitemid 44958629)
7. Buschmann IR, Busch HJ, Mies G, Hossmann KA. Therapeutic induction of arteriogenesis in hypoperfused rat brain via granulocyte-macrophage colony-stimulating factor. Circulation. 2003;108:610-615. (Pubitemid 36961178)
8. Schneider UC, Schilling L, Schroeck H, Nebe CT, Vajkoczy P, Woitzik J. Granulocyte-macrophage colony-stimulating factor-induced vessel growth restores cerebral blood supply after bilateral carotid artery occlusion. Stroke. 2007;38:1320-1328. (Pubitemid 351664288)
9. Todo K, Kitagawa K, Sasaki T, Omura-Matsuoka E, Terasaki Y, Oyama N, Yagita Y, Hori M. Granulocyte-macrophage colony-stimulating factor enhances leptomeningeal collateral growth induced by common carotid artery occlusion. Stroke. 2008;39:1875-1882.
10. Zbinden S, Zbinden R, Meier P, Windecker S, Seiler C. Safety and efficacy of subcutaneous-only granulocyte-macrophage colony-stimulating factor for collateral growth promotion in patients with coronary artery disease. J Am Coll Cardiol. 2005;46:1636-1642. (Pubitemid 41531615)
11. Bath PM, Sprigg N. Colony stimulating factors (including erythropoietin, granulocyte colony stimulating factor and analogues) for stroke. Cochrane Database Syst Rev. 2007;2:CD005207.
12. Coyle P. Diameter and length changes in cerebral collaterals after middle cerebral artery occlusion in the young rat. Anat Rec. 1984;210:357-364. (Pubitemid 15209788)
13. Scholz D, Ito W, Fleming I, Deindl E, Sauer A, Wiesnet M, Busse R, Schaper J, Schaper W. Ultrastructure and molecular histology of rabbit hind-limb collateral artery growth (arteriogenesis). Virchows Arch. 2000;436:257-270. (Pubitemid 30168685)
14. Schneider A, Krüger C, Steigleder T, Weber D, Pitzer C, Laage R, Aronowski J, Maurer MH, Gassler N, Mier W, Hasselblatt M, Kollmar R, Schwab S, Sommer C, Bach A, Kuhn HG, Schäbitz WR. The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis. J Clin Invest. 2005;115:2083-2098. (Pubitemid 41134150)
15. Minnerup J, Heidrich J, Wellmann J, Rogalewski A, Schneider A, Schäbitz WR. Meta-analysis of the efficacy of granulocyte-colony stimulating factor in animal models of focal cerebral ischemia. Stroke. 2008;39:1855-1861.
16. England TJ, Gibson CL, Bath PM. Granulocyte-colony stimulating factor in experimental stroke and its effects on infarct size and functional outcome: a systematic review. Brain Res Rev. 2009;62:71-82.
17. Bråtane BT, Bouley J, Schneider A, Bastan B, Henninger N, Fisher M. Granulocyte-colony stimulating factor delays PWI/DWI mismatch evolution and reduces final infarct volume in permanent-suture and embolic focal cerebral ischemia models in the rat. Stroke. 2009;40:3102-3106.
18. Komine-Kobayashi M, Zhang N, Liu M, Tanaka R, Hara H, Osaka A, Mochizuki H, Mizuno Y, Urabe T. Neuroprotective effect of recombinant human granulocyte colony-stimulating factor in transient focal ischemia of mice. J Cereb Blood Flow Metab. 2006;26:402-413.
19. Sehara Y, Hayashi T, Deguchi K, Zhang H, Tsuchiya A, Yamashita T, Lukic V, Nagai M, Kamiya T, Abe K. Decreased focal inflammatory response by G-CSF may improve stroke outcome after transient middle cerebral artery occlusion in rats. J Neurosci Res. 2007;85:2167-2174. (Pubitemid 47172148)
20. Anderlini P, Champlin RE. Biologic and molecular effects of granulocyte colony-stimulating factor in healthy individuals: recent findings and current challenges. Blood. 2008;111:1767-1772. (Pubitemid 351451480)
21. Bergmann CE, Hoefer IE, Meder B, Roth H, van Royen N, Breit SM, Jost MM, Aharinejad S, Hartmann S, Buschmann IR. Arteriogenesis depends on circulating monocytes and macrophage accumulation and is severely depressed in op/op mice. J Leukoc Biol. 2006;80:59-65. (Pubitemid 44835526)
22. Heil M, Ziegelhoeffer T, Pipp F, Kostin S, Martin S, Clauss M, Schaper W. Blood monocyte concentration is critical for enhancement of collateral artery growth. Am J Physiol Heart Circ Physiol. 2002;283:H2411-H2419. (Pubitemid 35345945)
23. Deindl E, Zaruba MM, Brunner S, Huber B, Mehl U, Assmann G, Hoefer IE, Mueller-Hoecker J, Franz WM. G-CSF administration after myocardial infarction in mice attenuates late ischemic cardiomyopathy by enhanced arteriogenesis. FASEB J. 2006;20:956-958.
24. Lee ST, Chu K, Jung KH, Ko SY, Kim EH, Sinn DI, Lee YS, Lo EH, Kim M, Roh JK. Granulocyte colony-stimulating factor enhances angiogenesis after focal cerebral ischemia. Brain Res. 2005;1058:120-128. (Pubitemid 41416806)
25. Strecker JK, Sevimli S, Schilling M, Klocke R, Nikol S, Schneider A, Schäbitz WR. Effects of G-CSF treatment on neutrophil mobilization and neurological outcome after transient focal ischemia. Exp Neurol. 2010;222:108-113.
26. Kang S, Yang Y, Li CJ, Gao R. Effectiveness and tolerability of administration of granulocyte colony-stimulating factor on left ventricular function in patients with myocardial infarction: a meta-analysis of randomized controlled trials. Clin Ther. 2007;29:2406-2418.