Neuroprotective therapy using granulocyte colony-stimulating factor for patients with worsening symptoms of compression myelopathy, part 1: A phase i and IIa clinical trial

European Spine Journal

Volumn 21, Issue 3, 2012, Pages 482-489

  Sakuma, Tsuyoshi ^a   Yamazaki, Masashi ^a   Okawa, Akihiko ^a   Takahashi, Hiroshi ^a   Kato, Kei ^a   Hashimoto, Mitsuhiro ^a   Hayashi, Koichi ^a   Furuya, Takeo ^a   Fujiyoshi, Takayuki ^a   Kawabe, Junko ^a   Mannoji, Chikato ^a   Kadota, Ryo ^a   Hashimoto, Masayuki ^a   Takahashi, Kazuhisa ^a   Koda, Masao ^a  

^a CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Clinical trial; Compression myelopathy; Granulocyte colony stimulating factor; Neuroprotective therapy

Indexed keywords

ANTIBIOTIC AGENT; C REACTIVE PROTEIN; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ABSENCE OF SIDE EFFECTS; ADULT; AGED; ANTIBIOTIC THERAPY; ARTICLE; CERVICAL MYELOPATHY; CERVICAL SPONDYLOTIC MYELOPATHY; CLINICAL ARTICLE; COMPRESSION MYELOPATHY; COMPUTER ASSISTED TOMOGRAPHY; DEBRIDEMENT; DECOMPRESSION SURGERY; DISEASE COURSE; DRUG EFFICACY; DRUG SAFETY; FEMALE; FOLLOW UP; GAIT DISORDER; HUMAN; LEUKOCYTE COUNT; MALE; MOTOR PERFORMANCE; MUSCLE STRENGTH; NEUROPROTECTION; NUCLEAR MAGNETIC RESONANCE IMAGING; OPEN STUDY; OSSIFICATION; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; POSTERIOR LONGITUDINAL LIGAMENT; POSTOPERATIVE INFECTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SCORING SYSTEM; SENSORY DYSFUNCTION; SENSORY SYSTEM; SPINAL CORD DISEASE; TREATMENT DURATION;

ADULT; AGED; DISEASE PROGRESSION; FEMALE; GRANULOCYTE COLONY-STIMULATING FACTOR; HUMANS; INJECTIONS, INTRAVENOUS; MALE; MIDDLE AGED; NEUROPROTECTIVE AGENTS; PARESTHESIA; QUADRIPLEGIA; RECOVERY OF FUNCTION; SPINAL CORD; SPINAL CORD COMPRESSION; SPONDYLOSIS; TREATMENT OUTCOME;

EID: 84862885870     PISSN: 09406719     EISSN: 14320932     Source Type: Journal    
DOI: 10.1007/s00586-011-2020-2     Document Type: Article

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