-
1
-
-
0033695682
-
Unregulated inflammation shortens human functional longevity
-
Brod, S.A. Unregulated inflammation shortens human functional longevity. Inflamm. Res., 2000, 49, 561-570.
-
(2000)
Inflamm. Res
, vol.49
, pp. 561-570
-
-
Brod, S.A.1
-
2
-
-
0030841350
-
Protein oxidation in aging, disease, and oxidative stress
-
Berlett, B.S.; Stadtman, E.R. Protein oxidation in aging, disease, and oxidative stress. J. Biol. Chem., 1997, 272, 20313-20316.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 20313-20316
-
-
Berlett, B.S.1
Stadtman, E.R.2
-
4
-
-
0346100345
-
Free radical-mediated oxidation of free amino acids and amino acid residues in proteins
-
Stadtman, E.R.; Levine, R.L. Free radical-mediated oxidation of free amino acids and amino acid residues in proteins. Amino. Acids, 2003, 25, 207-218.
-
(2003)
Amino. Acids
, vol.25
, pp. 207-218
-
-
Stadtman, E.R.1
Levine, R.L.2
-
5
-
-
6344292389
-
Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo. Role of mitochondrial reactive nitrogen species
-
Zou, M.H.; Kirkpatrick, S.S.; Davis, B.J.; Nelson, J.S.; Wiles, W.G.; Schlattner, U.; Neumann, D.; Brownlee, M.; Freeman, M.B.; Goldman, M.H. Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo. Role of mitochondrial reactive nitrogen species. J. Biol. Chem., 2004, 279, 43940-43951.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 43940-43951
-
-
Zou, M.H.1
Kirkpatrick, S.S.2
Davis, B.J.3
Nelson, J.S.4
Wiles, W.G.5
Schlattner, U.6
Neumann, D.7
Brownlee, M.8
Freeman, M.B.9
Goldman, M.H.10
-
7
-
-
80051978747
-
Use of Metformin in the Setting of Mild-to-Moderate Renal Insufficiency
-
Lipska, K.J.; Bailey, J.C.; Inzucchi, S.E. Use of Metformin in the Setting of Mild-to-Moderate Renal Insufficiency. Diabetes. Care., 2011, 34, 1431-1437.
-
(2011)
Diabetes. Care
, vol.34
, pp. 1431-1437
-
-
Lipska, K.J.1
Bailey, J.C.2
Inzucchi, S.E.3
-
8
-
-
84904642524
-
Metformin as a key to alternative activation of microglia?
-
Labuzek, K.; Gabryel, B.; Okopien, B. Metformin as a key to alternative activation of microglia? Postepy Hig. Med. Dosw., 2014, 68, 247-257.
-
(2014)
Postepy Hig. Med. Dosw
, vol.68
, pp. 247-257
-
-
Labuzek, K.1
Gabryel, B.2
Okopien, B.3
-
9
-
-
0028913896
-
Metformin. A review of its pharmacological properties and therapeutic use in non-insulin-dependent diabetes mellitus
-
Dunn, C.J.; Peters, D.H. Metformin. A review of its pharmacological properties and therapeutic use in non-insulin-dependent diabetes mellitus. Drugs, 1995, 49, 721-749.
-
(1995)
Drugs
, vol.49
, pp. 721-749
-
-
Dunn, C.J.1
Peters, D.H.2
-
10
-
-
0026011343
-
Reconsideration of inhibitory effect of metformin on intestinal glucose absorption
-
Wilcock, C.; Bailey, C.J. Reconsideration of inhibitory effect of metformin on intestinal glucose absorption. J. Pharm. Pharmacol., 1991, 43, 120-121.
-
(1991)
J. Pharm. Pharmacol.
, vol.43
, pp. 120-121
-
-
Wilcock, C.1
Bailey, C.J.2
-
11
-
-
29144523534
-
Human transporter protein that mediates the final excretion step for toxic organic cations
-
Otsuka, M.; Matsumoto, T.; Morimoto, R.; Arioka, S.; Omote, H.; Moriyama, Y. A human transporter protein that mediates the final excretion step for toxic organic cations. Proc. Natl. Acad. Sci. U. S. A., 2005, 102, 17923-17928.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 17923-17928
-
-
Otsuka, M.1
Matsumoto, T.2
Morimoto, R.3
Arioka, S.4
Omote, H.5
Moriyama, Y.A.6
-
12
-
-
38349085099
-
Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics
-
Shu, Y.; Brown, C.; Castro, R.A.; Shi, R.J.; Lin, E.T.; Owen, R.P.; Sheardown, S.A.; Yue, L.; Burchard, E.G.; Brett, C.M.; Giacomini, K.M. Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics. Clin. Pharmacol. Ther., 2008, 83, 273-280.
-
(2008)
Clin. Pharmacol. Ther
, vol.83
, pp. 273-280
-
-
Shu, Y.1
Brown, C.2
Castro, R.A.3
Shi, R.J.4
Lin, E.T.5
Owen, R.P.6
Sheardown, S.A.7
Yue, L.8
Burchard, E.G.9
Brett, C.M.10
Giacomini, K.M.11
-
13
-
-
54249106729
-
Genetic variants of the organic cation transporter 2 influence the disposition of metformin
-
Song, I.S.; Shin, H.J.; Shim, E.J.; Jung, I.S.; Kim, W.Y.; Shon, J.H.; Shin, J.G. Genetic variants of the organic cation transporter 2 influence the disposition of metformin. Clin. Pharmacol. Ther., 2008, 84, 559-562.
-
(2008)
Clin. Pharmacol. Ther
, vol.84
, pp. 559-562
-
-
Song, I.S.1
Shin, H.J.2
Shim, E.J.3
Jung, I.S.4
Kim, W.Y.5
Shon, J.H.6
Shin, J.G.7
-
14
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
Zhou, G.; Myers, R.; Li, Y.; Chen, Y.; Shen, X.; Fenyk-Melody, J.; Wu, M.; Ventre, J.; Doebber, T.; Fujii, N.; Musi, N.; Hirshman, M.F.; Goodyear, L.J.; Moller, D.E. Role of AMP-activated protein kinase in mechanism of metformin action. J. Clin. Invest., 2001, 108, 1167-1174.
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
Myers, R.2
Li, Y.3
Chen, Y.4
Shen, X.5
Fenyk-Melody, J.6
Wu, M.7
Ventre, J.8
Doebber, T.9
Fujii, N.10
Musi, N.11
Hirshman, M.F.12
Goodyear, L.J.13
Moller, D.E.14
-
15
-
-
0033673203
-
Mechanism by which metformin reduces glucose production in type 2 diabetes
-
Hundal, R.S.; Krssak, M.; Dufour, S.; Laurent, D.; Lebon, V.; Chandramouli, V.; Inzucchi, S.E.; Schumann, W.C.; Petersen, K.F.; Landau, B.R.; Shulman, G.I. Mechanism by which metformin reduces glucose production in type 2 diabetes. Diabetes, 2000, 49, 2063-2069.
-
(2000)
Diabetes
, vol.49
, pp. 2063-2069
-
-
Hundal, R.S.1
Krssak, M.2
Dufour, S.3
Laurent, D.4
Lebon, V.5
Chandramouli, V.6
Inzucchi, S.E.7
Schumann, W.C.8
Petersen, K.F.9
Landau, B.R.10
Shulman, G.I.11
-
16
-
-
0037008045
-
Metformin: An update
-
Kirpichnikov, D.; McFarlane, S.I.; Sowers, J.R. Metformin: an update. Ann. Intern. Med., 2002, 137, 25-33.
-
(2002)
Ann. Intern. Med.
, vol.137
, pp. 25-33
-
-
Kirpichnikov, D.1
McFarlane, S.I.2
Sowers, J.R.3
-
17
-
-
0029133235
-
Metabolic effects of metformin in non-insulin-dependent diabetes mellitus
-
Stumvoll, M.; Nurjhan, N.; Perriello, G.; Gerich, J.E. Metabolic effects of metformin in non-insulin-dependent diabetes mellitus. N. Engl. J. Med., 1995, 333, 550-554.
-
(1995)
N. Engl. J. Med.
, vol.333
, pp. 550-554
-
-
Stumvoll, M.1
Nurjhan, N.2
Perriello, G.3
Gerich, J.E.4
-
18
-
-
0034659785
-
Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain
-
Owen, M.R.; Doran, E.; Halestrap, A.P. Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain. Biochem. J., 2000, 348, 607-614.
-
(2000)
Biochem. J.
, vol.348
, pp. 607-614
-
-
Owen, M.R.1
Doran, E.2
Halestrap, A.P.3
-
19
-
-
0037341552
-
Metformin rapidly increases insulin receptor activation in human liver and signals preferentially through insulin-receptor substrate-2
-
Gunton, J.E.; Delhanty, P.J.; Takahashi, S.; Baxter, R.C. Metformin rapidly increases insulin receptor activation in human liver and signals preferentially through insulin-receptor substrate-2. J. Clin. Endocrinol. Metab., 2003, 88, 1323-1332.
-
(2003)
J. Clin. Endocrinol. Metab.
, vol.88
, pp. 1323-1332
-
-
Gunton, J.E.1
Delhanty, P.J.2
Takahashi, S.3
Baxter, R.C.4
-
20
-
-
0031881129
-
Further evidence for a central role of adipose tissue in the antihyperglycemic effect of metformin
-
Abbasi, F.; Carantoni, M.; Chen, Y.D.; Reaven, G.M. Further evidence for a central role of adipose tissue in the antihyperglycemic effect of metformin. Diabetes Care, 1998, 21, 1301-1305.
-
(1998)
Diabetes Care
, vol.21
, pp. 1301-1305
-
-
Abbasi, F.1
Carantoni, M.2
Chen, Y.D.3
Reaven, G.M.4
-
21
-
-
0032954778
-
Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity
-
Dresner, A.; Laurent, D.; Marcucci, M.; Griffin, M.E.; Dufour, S.; Cline, G.W.; Slezak, L.A.; Andersen, D.K.; Hundal, R.S.; Rothman, D.L.; Petersen, K.F.; Shulman, G.I. Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity. J. Clin. Invest., 1999, 103, 253-259.
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 253-259
-
-
Dresner, A.1
Laurent, D.2
Marcucci, M.3
Griffin, M.E.4
Dufour, S.5
Cline, G.W.6
Slezak, L.A.7
Andersen, D.K.8
Hundal, R.S.9
Rothman, D.L.10
Petersen, K.F.11
Shulman, G.I.12
-
22
-
-
79958801131
-
Metformin-mechanisms of action and use for the treatment of type 2 diabetes mellitus
-
Grzybowska, M.; Bober, J.; Olszewska, M. Metformin-mechanisms of action and use for the treatment of type 2 diabetes mellitus. Postepy Hig. Med. Dosw., 2011, 65, 277-285.
-
(2011)
Postepy Hig. Med. Dosw.
, vol.65
, pp. 277-285
-
-
Grzybowska, M.1
Bober, J.2
Olszewska, M.3
-
23
-
-
0029778182
-
Metformin improves hemodynamic and rheological responses to L-arginine in NIDDM patients
-
Marfella, R.; Acampora, R.; Verrazzo, G.; Ziccardi, P.; De, R.N.; Giunta, R.; Giugliano, D. Metformin improves hemodynamic and rheological responses to L-arginine in NIDDM patients. Diabetes Care, 1996, 19, 934-939.
-
(1996)
Diabetes Care
, vol.19
, pp. 934-939
-
-
Marfella, R.1
Acampora, R.2
Verrazzo, G.3
Ziccardi, P.4
De, R.N.5
Giunta, R.6
Giugliano, D.7
-
24
-
-
0035312620
-
Improved endothelial function with metformin in type 2 diabetes mellitus
-
Mather, K.J.; Verma, S.; Anderson, T.J. Improved endothelial function with metformin in type 2 diabetes mellitus. J. Am. Coll. Cardiol., 2001, 37, 1344-1350.
-
(2001)
J. Am. Coll. Cardiol.
, vol.37
, pp. 1344-1350
-
-
Mather, K.J.1
Verma, S.2
Anderson, T.J.3
-
25
-
-
0037328928
-
Malonyl-CoA and AMPactivated protein kinase (AMPK): Possible links between insulin resistance in muscle and early endothelial cell damage in diabetes
-
Ruderman, N.B.; Cacicedo, J.M.; Itani, S.; Yagihashi, N.; Saha, A.K.; Ye, J.M.; Chen, K.; Zou, M.; Carling, D.; Boden, G.; Cohen, R.A.; Keaney, J.; Kraegen, E.W.; Ido, Y. Malonyl-CoA and AMPactivated protein kinase (AMPK): possible links between insulin resistance in muscle and early endothelial cell damage in diabetes. Biochem. Soc. Trans., 2003, 31, 202-206.
-
(2003)
Biochem. Soc. Trans
, vol.31
, pp. 202-206
-
-
Ruderman, N.B.1
Cacicedo, J.M.2
Itani, S.3
Yagihashi, N.4
Saha, A.K.5
Ye, J.M.6
Chen, K.7
Zou, M.8
Carling, D.9
Boden, G.10
Cohen, R.A.11
Keaney, J.12
Kraegen, E.W.13
Ido, Y.14
-
26
-
-
0036299982
-
Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes
-
Musi, N.; Hirshman, M.F.; Nygren, J.; Svanfeldt, M.; Bavenholm, P.; Rooyackers, O.; Zhou, G.; Williamson, J.M.; Ljunqvist, O.; Efendic, S.; Moller, D.E.; Thorell, A.; Goodyear, L.J. Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes. Diabetes, 2002, 51, 2074-2081.
-
(2002)
Diabetes
, vol.51
, pp. 2074-2081
-
-
Musi, N.1
Hirshman, M.F.2
Nygren, J.3
Svanfeldt, M.4
Bavenholm, P.5
Rooyackers, O.6
Zhou, G.7
Williamson, J.M.8
Ljunqvist, O.9
Efendic, S.10
Moller, D.E.11
Thorell, A.12
Goodyear, L.J.13
-
27
-
-
0036324142
-
The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism
-
Hawley, S.A.; Gadalla, A.E.; Olsen, G.S.; Hardie, D.G. The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism. Diabetes, 2002, 51, 2420-2425.
-
(2002)
Diabetes
, vol.51
, pp. 2420-2425
-
-
Hawley, S.A.1
Gadalla, A.E.2
Olsen, G.S.3
Hardie, D.G.4
-
28
-
-
84863046265
-
A novel cardioprotective agent in cardiac transplantation: Metformin activation of AMPactivated protein kinase decreases acute ischemia-reperfusion injury and chronic rejection
-
Chin, J.T.; Troke, J.J.; Kimura, N.; Itoh, S.; Wang, X.; Palmer, O.P.; Robbins, R.C.; Fischbein, M.P. A novel cardioprotective agent in cardiac transplantation: metformin activation of AMPactivated protein kinase decreases acute ischemia-reperfusion injury and chronic rejection. Yale J. Biol. Med., 2011, 84, 423-432.
-
(2011)
Yale J. Biol. Med
, vol.84
, pp. 423-432
-
-
Chin, J.T.1
Troke, J.J.2
Kimura, N.3
Itoh, S.4
Wang, X.5
Palmer, O.P.6
Robbins, R.C.7
Fischbein, M.P.8
-
29
-
-
33744976813
-
Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMPactivated protein kinase activation in vascular endothelial cells
-
Hattori, Y.; Suzuki, K.; Hattori, S.; Kasai, K. Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMPactivated protein kinase activation in vascular endothelial cells. Hypertension, 2006, 47, 1183-1188.
-
(2006)
Hypertension
, vol.47
, pp. 1183-1188
-
-
Hattori, Y.1
Suzuki, K.2
Hattori, S.3
Kasai, K.4
-
30
-
-
0037092995
-
Diabetes and atherosclerosis: Epidemiology, pathophysiology, and management
-
Beckman, J.A.; Creager, M.A.; Libby, P. Diabetes and atherosclerosis: epidemiology, pathophysiology, and management. JAMA, 2002, 287, 2570-2581.
-
(2002)
JAMA
, vol.287
, pp. 2570-2581
-
-
Beckman, J.A.1
Creager, M.A.2
Libby, P.3
-
31
-
-
33846863589
-
Nitric oxide and peroxynitrite in health and disease
-
Pacher, P.; Beckman, J.S.; Liaudet, L. Nitric oxide and peroxynitrite in health and disease. Physiol. Rev., 2007, 87, 315-424.
-
(2007)
Physiol. Rev
, vol.87
, pp. 315-424
-
-
Pacher, P.1
Beckman, J.S.2
Liaudet, L.3
-
32
-
-
69549097703
-
New users of metformin are at low risk of incident cancer: A cohort study among people with type 2 diabetes
-
Libby, G.; Donnelly, L.A.; Donnan, P.T.; Alessi, D.R.; Morris, A.D.; Evans, J.M. New users of metformin are at low risk of incident cancer: a cohort study among people with type 2 diabetes. Diabetes Care, 2009, 32, 1620-1625.
-
(2009)
Diabetes Care
, vol.32
, pp. 1620-1625
-
-
Libby, G.1
Donnelly, L.A.2
Donnan, P.T.3
Alessi, D.R.4
Morris, A.D.5
Evans, J.M.6
-
33
-
-
70350236538
-
Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission
-
Hirsch, H.A.; Iliopoulos, D.; Tsichlis, P.N.; Struhl, K. Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission. Cancer Res., 2009, 69, 7507-7511.
-
(2009)
Cancer Res.
, vol.69
, pp. 7507-7511
-
-
Hirsch, H.A.1
Iliopoulos, D.2
Tsichlis, P.N.3
Struhl, K.4
-
34
-
-
84975765470
-
Cholesterol-friend or foe of the brain
-
Boguslawski, W.; Foerster, J.; Siedlecka, K. Cholesterol-friend or foe of the brain. Geront. Pol., 2008, 3, 160-162.
-
(2008)
Geront. Pol
, vol.3
, pp. 160-162
-
-
Boguslawski, W.1
Foerster, J.2
Siedlecka, K.3
-
35
-
-
84937635957
-
Antidiabetic agents: Potential anti-inflammatory activity beyond glucose control
-
[Epub ahead of print]
-
Scheen, A.J.; Esser, N.; Paquot, N. Antidiabetic agents: Potential anti-inflammatory activity beyond glucose control. Diabetes Metab., 2015, doi: 10.1016/j.diabet.2015.02.003. [Epub ahead of print]
-
(2015)
Diabetes Metab.
-
-
Scheen, A.J.1
Esser, N.2
Paquot, N.3
-
36
-
-
84975702851
-
Peroxynitrite a strong biological oxidant
-
Bijak, M.; Ponczek, M.; Saluk, J.; Chabielska, M.; Stepniak, J.; Nowak, P. Peroxynitrite a strong biological oxidant. Chemical News, 2012, 66, 623-636.
-
(2012)
Chemical News
, vol.66
, pp. 623-636
-
-
Bijak, M.1
Ponczek, M.2
Saluk, J.3
Chabielska, M.4
Stepniak, J.5
Nowak, P.6
-
37
-
-
0028234728
-
Oxidative chemistry of peroxynitrite
-
Beckman, J.S.; Chen, J.; Ischiropoulos, H.; Crow, J.P. Oxidative chemistry of peroxynitrite. Methods Enzymol., 1994, 233, 229-240.
-
(1994)
Methods Enzymol.
, vol.233
, pp. 229-240
-
-
Beckman, J.S.1
Chen, J.2
Ischiropoulos, H.3
Crow, J.P.4
-
38
-
-
0029682870
-
Oxidative damage and tyrosine nitration from peroxynitrite
-
Beckman, J.S. Oxidative damage and tyrosine nitration from peroxynitrite. Chem. Res. Toxicol., 1996, 9, 836-844.
-
(1996)
Chem. Res. Toxicol
, vol.9
, pp. 836-844
-
-
Beckman, J.S.1
-
39
-
-
84863626043
-
Protective effects of grape seed extract against oxidative and nitrative damage of plasma proteins
-
Bijak, M.; Kolodziejczyk-Czepas, J.; Ponczek, M.B.; Saluk, J.; Nowak, P. Protective effects of grape seed extract against oxidative and nitrative damage of plasma proteins. Int. J. Biol. Macromol., 2012, 51, 183-187.
-
(2012)
Int. J. Biol. Macromol.
, vol.51
, pp. 183-187
-
-
Bijak, M.1
Kolodziejczyk-Czepas, J.2
Ponczek, M.B.3
Saluk, J.4
Nowak, P.5
-
40
-
-
79952108292
-
Oxidative stress in haemostasis
-
Nowak, P.; Olas, B.; Wachowicz, B. Oxidative stress in haemostasis. Postepy Biochem., 2010, 56, 239-247.
-
(2010)
Postepy Biochem.
, vol.56
, pp. 239-247
-
-
Nowak, P.1
Olas, B.2
Wachowicz, B.3
-
41
-
-
28244466264
-
5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase
-
Rattan, R.; Giri, S.; Singh, A.K.; Singh, I. 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase. J. Biol. Chem., 2005, 280, 39582-39593.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 39582-39593
-
-
Rattan, R.1
Giri, S.2
Singh, A.K.3
Singh, I.4
-
42
-
-
84863700565
-
Exploiting the anti-inflammatory effects of AMP-activated protein kinase activation
-
Salt, I.P.; Palmer, T.M. Exploiting the anti-inflammatory effects of AMP-activated protein kinase activation. Expert. Opin. Investig. Drugs, 2012, 21, 1155-1167.
-
(2012)
Expert. Opin. Investig. Drugs
, vol.21
, pp. 1155-1167
-
-
Salt, I.P.1
Palmer, T.M.2
-
43
-
-
17644396349
-
Immunology of multiple sclerosis
-
Sospedra, M.; Martin, R. Immunology of multiple sclerosis. Annu. Rev. Immunol., 2005, 23, 683-747.
-
(2005)
Annu. Rev. Immunol
, vol.23
, pp. 683-747
-
-
Sospedra, M.1
Martin, R.2
-
44
-
-
0038182547
-
Diverse targets for intervention during inflammatory and neurodegenerative phases of multiple sclerosis
-
Zamvil, S.S.; Steinman, L. Diverse targets for intervention during inflammatory and neurodegenerative phases of multiple sclerosis. Neuron, 2003, 38, 685-688.
-
(2003)
Neuron
, vol.38
, pp. 685-688
-
-
Zamvil, S.S.1
Steinman, L.2
-
45
-
-
0035555366
-
Autoimmune diseases: Genes, bugs and failed regulation
-
Ermann, J.; Fathman, C.G. Autoimmune diseases: genes, bugs and failed regulation. Nat. Immunol., 2001, 2, 759-761.
-
(2001)
Nat. Immunol
, vol.2
, pp. 759-761
-
-
Ermann, J.1
Fathman, C.G.2
-
46
-
-
84855301917
-
Oxidative modification of patient's plasma proteins and its role in pathogenesis of multiple sclerosis
-
Miller, E.; Walczak, A.; Saluk, J.; Ponczek, M.B.; Majsterek, I. Oxidative modification of patient's plasma proteins and its role in pathogenesis of multiple sclerosis. Clin. Biochem., 2012, 45, 26-30.
-
(2012)
Clin. Biochem
, vol.45
, pp. 26-30
-
-
Miller, E.1
Walczak, A.2
Saluk, J.3
Ponczek, M.B.4
Majsterek, I.5
-
47
-
-
79954445480
-
Effects of whole-body cryotherapy on a total antioxidative status and activities of antioxidative enzymes in blood of depressive multiple sclerosis patients
-
Miller, E.; Mrowicka, M.; Malinowska, K.; Mrowicki, J.; Saluk-Juszczak, J.; Kedziora, J. Effects of whole-body cryotherapy on a total antioxidative status and activities of antioxidative enzymes in blood of depressive multiple sclerosis patients. World J. Biol. Psychiatry, 2011, 12, 223-227.
-
(2011)
World J. Biol. Psychiatry
, vol.12
, pp. 223-227
-
-
Miller, E.1
Mrowicka, M.2
Malinowska, K.3
Mrowicki, J.4
Saluk-Juszczak, J.5
Kedziora, J.6
-
48
-
-
67649196932
-
Metformin attenuated the autoimmune disease of the central nerv ous system in animal models of multiple sclerosis
-
Nath, N.; Khan, M.; Paintlia, M.K.; Singh, I.; Hoda, M.N.; Giri, S. Metformin attenuated the autoimmune disease of the central nerv ous system in animal models of multiple sclerosis. J. Immunol., 2009, 182, 8005-8014.
-
(2009)
J. Immunol.
, vol.182
, pp. 8005-8014
-
-
Nath, N.1
Khan, M.2
Paintlia, M.K.3
Singh, I.4
Hoda, M.N.5
Giri, S.6
-
49
-
-
4043162976
-
The differential effects of metformin on markers of endothelial activation and inflammation in subjects with impaired glucose tolerance: A placebo-controlled, randomized clinical trial
-
Caballero, A.E.; Delgado, A.; Aguilar-Salinas, C.A.; Herrera, A.N.; Castillo, J.L.; Cabrera, T.; Gomez-Perez, F.J.; Rull, J.A. The differential effects of metformin on markers of endothelial activation and inflammation in subjects with impaired glucose tolerance: a placebo-controlled, randomized clinical trial. J. Clin. Endocrinol. Metab., 2004, 89, 3943-3948.
-
(2004)
J. Clin. Endocrinol. Metab.
, vol.89
, pp. 3943-3948
-
-
Caballero, A.E.1
Delgado, A.2
Aguilar-Salinas, C.A.3
Herrera, A.N.4
Castillo, J.L.5
Cabrera, T.6
Gomez-Perez, F.J.7
Rull, J.A.8
-
50
-
-
19944433033
-
Effects of short-term treatment with metformin on markers of endothelial function and inflammatory activity in type 2 diabetes mellitus: A randomized, placebo-controlled trial
-
De Jager, J.; Kooy, A.; Lehert, P.; Bets, D.; Wulffele, M.G.; Teerlink, T.; Scheffer, P.G.; Schalkwijk, C.G.; Donker, A.J.; Stehouwer, C.D. Effects of short-term treatment with metformin on markers of endothelial function and inflammatory activity in type 2 diabetes mellitus: a randomized, placebo-controlled trial. J. Intern. Med., 2005, 257, 100-109.
-
(2005)
J. Intern. Med.
, vol.257
, pp. 100-109
-
-
De Jager, J.1
Kooy, A.2
Lehert, P.3
Bets, D.4
Wulffele, M.G.5
Teerlink, T.6
Scheffer, P.G.7
Schalkwijk, C.G.8
Donker, A.J.9
Stehouwer, C.D.10
-
51
-
-
17044372405
-
CCL2 and CCL5 mediate leukocyte adhesion in experimental autoimmune encephalomyelitis--an intravital microscopy study
-
dos Santos, A.C.; Barsante, M.M.; Arantes, R.M.; Bernard, C.C.; Teixeira, M.M.; Carvalho-Tavares, J. CCL2 and CCL5 mediate leukocyte adhesion in experimental autoimmune encephalomyelitis--an intravital microscopy study. J. Neuroimmunol., 2005, 162, 122-129.
-
(2005)
J. Neuroimmunol.
, vol.162
, pp. 122-129
-
-
Dos Santos, A.C.1
Barsante, M.M.2
Arantes, R.M.3
Bernard, C.C.4
Teixeira, M.M.5
Carvalho-Tavares, J.6
-
52
-
-
60549101884
-
Synthesis of alpha-amyrin derivatives and their in vivo antihyperglycemic activity
-
Narender, T.; Khaliq, T.; Singh, A.B.; Joshi, M.D.; Mishra, P.; Chaturvedi, J.P.; Srivastava, A.K.; Maurya, R.; Agarwal, S.C. Synthesis of alpha-amyrin derivatives and their in vivo antihyperglycemic activity. Eur. J. Med. Chem., 2009, 44, 1215-1222.
-
(2009)
Eur. J. Med. Chem.
, vol.44
, pp. 1215-1222
-
-
Narender, T.1
Khaliq, T.2
Singh, A.B.3
Joshi, M.D.4
Mishra, P.5
Chaturvedi, J.P.6
Srivastava, A.K.7
Maurya, R.8
Agarwal, S.C.9
-
53
-
-
84880628985
-
AMP-activated protein kinase signaling protects oligodendrocytes that restore central nervous system functions in an experimental autoimmune encephalomyelitis model
-
Paintlia, A.S.; Paintlia, M.K.; Mohan, S.; Singh, A.K.; Singh, I. AMP-activated protein kinase signaling protects oligodendrocytes that restore central nervous system functions in an experimental autoimmune encephalomyelitis model. Am. J. Pathol., 2013, 183, 526-541.
-
(2013)
Am. J. Pathol.
, vol.183
, pp. 526-541
-
-
Paintlia, A.S.1
Paintlia, M.K.2
Mohan, S.3
Singh, A.K.4
Singh, I.5
-
55
-
-
64349115078
-
-
Ronnett,1,2 Santosh Ramamurthy,1 Amy M. Kleman,1 Leslie E. Landree,1 and Susan Aja3
-
Gabriele V. Ronnett,1,2 Santosh Ramamurthy,1 Amy M. Kleman,1 Leslie E. Landree,1 and Susan Aja3 AMPK in the Brain: Its Roles in Energy Balance and Neuroprotection J Neurochem. 2009 May; 109(Suppl 1), 17-23.
-
(2009)
AMPK in the Brain: Its Roles in Energy Balance and Neuroprotection J Neurochem
, vol.109
, pp. 17-23
-
-
Gabriele, V.1
-
56
-
-
84855172814
-
The pathogenesis of rheumatoid arthritis
-
McInnes, I.B.; Schett, G. The pathogenesis of rheumatoid arthritis. N. Engl. J. Med., 2011, 365, 2205-2219.
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 2205-2219
-
-
McInnes, I.B.1
Schett, G.2
-
57
-
-
67049097104
-
Developmental plasticity of Th17 and Treg cells
-
Lee, Y.K.; Mukasa, R.; Hatton, R.D.; Weaver, C.T. Developmental plasticity of Th17 and Treg cells. Curr. Opin. Immunol., 2009, 21, 274-280.
-
(2009)
Curr. Opin. Immunol
, vol.21
, pp. 274-280
-
-
Lee, Y.K.1
Mukasa, R.2
Hatton, R.D.3
Weaver, C.T.4
-
58
-
-
84886859944
-
Metabolic regulation of osteoclast differentiation and function
-
Indo, Y.; Takeshita, S.; Ishii, K.A.; Hoshii, T.; Aburatani, H.; Hirao, A.; Ikeda, K. Metabolic regulation of osteoclast differentiation and function. J. Bone Miner. Res., 2013, 28, 2392-2399.
-
(2013)
Br. J. Anaesth
, vol.28
, pp. 2392-2399
-
-
Indo, Y.1
Takeshita, S.2
Ishii, K.A.3
Hoshii, T.4
Aburatani, H.5
Hirao, A.6
Ikeda, K.7
-
59
-
-
84875999344
-
Metformin downregulates Th17 cells differentiation and attenuates murine autoimmune arthritis
-
Kang, K.Y.; Kim, Y.K.; Yi, H.; Kim, J.; Jung, H.R.; Kim, I.J.; Cho, J.H.; Park, S.H.; Kim, H.Y.; Ju, J.H. Metformin downregulates Th17 cells differentiation and attenuates murine autoimmune arthritis. Int. Immunopharmacol., 2013, 16, 85-92.
-
(2013)
Int. Immunopharmacol.
, vol.16
, pp. 85-92
-
-
Kang, K.Y.1
Kim, Y.K.2
Yi, H.3
Kim, J.4
Jung, H.R.5
Kim, I.J.6
Cho, J.H.7
Park, S.H.8
Kim, H.Y.9
Ju, J.H.10
-
60
-
-
84907228811
-
Metformin attenuates experimental autoimmune arthritis through reciprocal regulation of Th/Treg balance and osteoclastogenesis
-
Son, H.; Lee, J.; Lee, S.; Kim, E.; Park, M.; Kim, K.; Park, S.; Cho, M. Metformin attenuates experimental autoimmune arthritis through reciprocal regulation of Th/Treg balance and osteoclastogenesis. Med. in Inflam., 2014, 2014, 973986.
-
(2014)
Med. In Inflam., 2014
-
-
Son, H.1
Lee, J.2
Lee, S.3
Kim, E.4
Park, M.5
Kim, K.6
Park, S.7
Cho, M.8
-
61
-
-
79251626345
-
Metformin decreases thyrotropin in overweight women with polycystic ovarian syndrom and hypothyroidism
-
Taghavi, S.; Rokini, H.; Fatemi, S. Metformin decreases thyrotropin in overweight women with polycystic ovarian syndrom and hypothyroidism. Diab. Vasc. Dis. Res., 2011, 8, 47-48.
-
(2011)
Diab. Vasc. Dis. Res.
, vol.8
, pp. 47-48
-
-
Taghavi, S.1
Rokini, H.2
Fatemi, S.3
-
62
-
-
84939466634
-
Lipodystrophies: Adipose tissue disorders with severe metabolic implications
-
[Epub ahead of print]
-
Cortes, V.A.; Fernandez-Galilea, M. Lipodystrophies: adipose tissue disorders with severe metabolic implications. J. Physiol. Biochem., 2015, [Epub ahead of print].
-
(2015)
J. Physiol. Biochem
-
-
Cortes, V.A.1
Fernandez-Galilea, M.2
-
63
-
-
77953395291
-
Acquired generalized lipodystrophy associated with autoimmune hepatitis and low serum C4 level
-
Eren, E.; Ozkan, T.B.; Cakir, E.D.; Saglam, H.; Tarim, O. Acquired generalized lipodystrophy associated with autoimmune hepatitis and low serum C4 level. J. Clin. Res. Pediatr. Endocrinol., 2010, 2, 39-42.
-
(2010)
J. Clin. Res. Pediatr. Endocrinol.
, vol.2
, pp. 39-42
-
-
Eren, E.1
Ozkan, T.B.2
Cakir, E.D.3
Saglam, H.4
Tarim, O.5
-
64
-
-
80655145234
-
Clinical review#: Lipodystrophies: Genetic and acquired body fat disorders
-
Garg, A. Clinical review#: Lipodystrophies: genetic and acquired body fat disorders. J. Clin. Endocrinol. Metab., 2011, 96, 3313-3325.
-
(2011)
J. Clin. Endocrinol. Metab.
, vol.96
, pp. 3313-3325
-
-
Garg, A.1
-
65
-
-
84871430894
-
Metformin: The hidden chronicles of a magic drug
-
Mahmood, K.; Naeem, M.; Rahimnajjad, N.A. Metformin: the hidden chronicles of a magic drug. Eur. J. Intern. Med., 2013, 24, 20-26.
-
(2013)
Eur. J. Intern. Med.
, vol.24
, pp. 20-26
-
-
Mahmood, K.1
Naeem, M.2
Rahimnajjad, N.A.3
-
66
-
-
84873733300
-
Metformin: An old but still the best treatment for type 2 diabetes
-
Rojas, L.B.A.; Gomes, M.B. Metformin: an old but still the best treatment for type 2 diabetes. Diabetol Metab Syndr., 2013, 5, 6.
-
(2013)
Diabetol Metab Syndr.
, vol.5
, pp. 6
-
-
Rojas, L.B.A.1
Gomes, M.B.2
-
67
-
-
84919461875
-
Dipeptidyl peptidase-4 inhibitors do not increase the risk of cardiovascular events in type 2 diabetes: A cohort study
-
Kim, S.C.; Glynn, R.J.; Liu, J.; Everett, B.M.; Goldfine, A.B. Dipeptidyl peptidase-4 inhibitors do not increase the risk of cardiovascular events in type 2 diabetes: a cohort study. Acta Diabetol., 2014, 51, 1015-1023.
-
(2014)
Acta Diabetol.
, vol.51
, pp. 1015-1023
-
-
Kim, S.C.1
Glynn, R.J.2
Liu, J.3
Everett, B.M.4
Goldfine, A.B.5
-
68
-
-
0037038402
-
The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease
-
Youssef, S.; Stuve, O.; Patarroyo, J.C.; Ruiz, P.J.; Radosevich, J.L.; Hur, E.M.; Bravo, M.; Mitchell, D.J.; Sobel, R.A.; Steinman, L.; Zamvil, S.S. The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease. Nature, 2002, 420, 78-84.
-
(2002)
Nature
, vol.420
, pp. 78-84
-
-
Youssef, S.1
Stuve, O.2
Patarroyo, J.C.3
Ruiz, P.J.4
Radosevich, J.L.5
Hur, E.M.6
Bravo, M.7
Mitchell, D.J.8
Sobel, R.A.9
Steinman, L.10
Zamvil, S.S.11
-
69
-
-
3042761085
-
Regulation of gene expression associated with acute experimental autoimmune encephalomyelitis by Lovastatin
-
Paintlia, A.S.; Paintlia, M.K.; Singh, A.K.; Stanislaus, R.; Gilg, A.G.; Barbosa, E.; Singh, I. Regulation of gene expression associated with acute experimental autoimmune encephalomyelitis by Lovastatin. J. Neurosci. Res., 2004, 77, 63-81.
-
(2004)
J. Neurosci. Res.
, vol.77
, pp. 63-81
-
-
Paintlia, A.S.1
Paintlia, M.K.2
Singh, A.K.3
Stanislaus, R.4
Gilg, A.G.5
Barbosa, E.6
Singh, I.7
-
70
-
-
84867352003
-
Inhibition of interferon-beta responses in multiple sclerosis immune cells associated with high-dose statins
-
Feng, X.; Han, D.; Kilaru, B.K.; Franek, B.S.; Niewold, T.B.; Reder, A.T. Inhibition of interferon-beta responses in multiple sclerosis immune cells associated with high-dose statins. Arch. Neurol., 2012, 69, 1303-1309.
-
(2012)
Arch. Neurol
, vol.69
, pp. 1303-1309
-
-
Feng, X.1
Han, D.2
Kilaru, B.K.3
Franek, B.S.4
Niewold, T.B.5
Reder, A.T.6
-
71
-
-
0030700441
-
Role of astroglia and insulin-like growth factor-I in gonadal hormone-dependent synaptic plasticity
-
Fernandez-Galaz, M.C.; Morschl, E.; Chowen, J.A.; Torres-Aleman, I.; Naftolin, F.; Garcia-Segura, L.M. Role of astroglia and insulin-like growth factor-I in gonadal hormone-dependent synaptic plasticity. Brain Res. Bull., 1997, 44, 525-531.
-
(1997)
Brain Res. Bull
, vol.44
, pp. 525-531
-
-
Fernandez-Galaz, M.C.1
Morschl, E.2
Chowen, J.A.3
Torres-Aleman, I.4
Naftolin, F.5
Garcia-Segura, L.M.6
-
72
-
-
0036281689
-
CNTF is a major protective factor in demyelinating CNS disease: A neurotrophic cytokine as modulator in neuroinflammation
-
Linker, R.A.; Maurer, M.; Gaupp, S.; Martini, R.; Holtmann, B.; Giess, R.; Rieckmann, P.; Lassmann, H.; Toyka, K.V.; Sendtner, M.; Gold, R. CNTF is a major protective factor in demyelinating CNS disease: a neurotrophic cytokine as modulator in neuroinflammation. Nat. Med., 2002, 8, 620-624.
-
(2002)
Nat. Med
, vol.8
, pp. 620-624
-
-
Linker, R.A.1
Maurer, M.2
Gaupp, S.3
Martini, R.4
Holtmann, B.5
Giess, R.6
Rieckmann, P.7
Lassmann, H.8
Toyka, K.V.9
Sendtner, M.10
Gold, R.11
-
73
-
-
30044451754
-
The immunomodulator glatiramer acetate augments the expression of neurotrophic factors in brains of experimental autoimmune encephalomyelitis mice
-
Aharoni, R.; Eilam, R.; Domev, H.; Labunskay, G.; Sela, M.; Arnon, R. The immunomodulator glatiramer acetate augments the expression of neurotrophic factors in brains of experimental autoimmune encephalomyelitis mice. Proc. Natl. Acad. Sci. U. S. A., 2005, 102, 19045-19050.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 19045-19050
-
-
Aharoni, R.1
Eilam, R.2
Domev, H.3
Labunskay, G.4
Sela, M.5
Arnon, R.6
-
74
-
-
34447128136
-
Activation of astrocytes by CNTF induces metabolic plasticity and increases resistance to metabolic insults
-
Escartin, C.; Pierre, K.; Colin, A.; Brouillet, E.; Delzescaux, T.; Guillermier, M.; Dhenain, M.; Deglon, N.; Hantraye, P.; Pellerin, L.; Bonvento, G. Activation of astrocytes by CNTF induces metabolic plasticity and increases resistance to metabolic insults. J. Neurosci., 2007, 27, 7094-7104.
-
(2007)
J. Neurosci.
, vol.27
, pp. 7094-7104
-
-
Escartin, C.1
Pierre, K.2
Colin, A.3
Brouillet, E.4
Delzescaux, T.5
Guillermier, M.6
Dhenain, M.7
Deglon, N.8
Hantraye, P.9
Pellerin, L.10
Bonvento, G.11
-
75
-
-
56749180855
-
Brain-derived neurotrophic factor functions as a metabotrophin to mediate the effects of exercise on cognition
-
Gomez-Pinilla, F.; Vaynman, S.; Ying, Z. Brain-derived neurotrophic factor functions as a metabotrophin to mediate the effects of exercise on cognition. Eur. J. Neurosci., 2008, 28, 2278-2287.
-
(2008)
Eur. J. Neurosci.
, vol.28
, pp. 2278-2287
-
-
Gomez-Pinilla, F.1
Vaynman, S.2
Ying, Z.3
|