Metformin decreases thyrotropin in overweight women with polycystic ovarian syndrome and hypothyroidism

Diabetes and Vascular Disease Research

Volumn 8, Issue 1, 2011, Pages 47-48

  Morteza Taghavi, S ^a   Rokni, Hale ^a   Fatemi, Sedigheh ^a  

^a MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Hypothyroidism; metformin; polycystic ovarian syndrome (PCOS); thyrotropin (TSH)

Indexed keywords

LIOTHYRONINE; METFORMIN; PLACEBO; THYROTROPIN; THYROXINE;

ARTICLE; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DRUG EFFECT; FEMALE; HUMAN; HYPOTHYROIDISM; LIOTHYRONINE BLOOD LEVEL; OBESITY; OVARY POLYCYSTIC DISEASE; PATIENT SELECTION; RANDOMIZED CONTROLLED TRIAL; THYROID FUNCTION; THYROID FUNCTION TEST; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL; TREATMENT DURATION; TREATMENT OUTCOME;

FEMALE; HUMANS; HYPOGLYCEMIC AGENTS; HYPOTHYROIDISM; METFORMIN; OVERWEIGHT; POLYCYSTIC OVARY SYNDROME; THYROID GLAND; THYROID HORMONES;

EID: 79251626345     PISSN: 14791641     EISSN: None     Source Type: Journal    
DOI: 10.1177/1479164110391917     Document Type: Article

References (6)

1. Janssen OE, Mehlmauer N., Hahn S. et al. High prevalence of autoimmune thyroiditis in patients with polycystic ovary syndrome. Eur J Endocrinol 2004 ; 150: 363-369.
2. Cappelli C., Rotondi M., Pirola I. et al. TSH-lowering effect of metformin in type 2 diabetes. Diabetes Care 2009 ; 32: 1589-1590.
3. Díez JJ, Iglesias P. Spontaneous subclinical hypothyroidism in patients older than 55 years: an analysis of natural course and risk factors for the development of overt thyroid failure. J Clin Endocrinol Metab 2004 ; 89: 4890-7.
4. Vigersky RA, Filmore-Nassar A. and Glass AR Thyrotropin suppression by metformin. J Clin Endocrinol Metab 2006 ; 91: 225-227
5. Quigley ME, Rakoff JS and Yen SSC. Increased luteinizing hormone sensitivity to dopamine inhibition in polycystic ovary syndrome. J Clin Endocrinol Metab 1981 ; 52: 231-234.
6. Ortega-González C., Cardoza L., Coutiño B. et al. Insulin sensitizing drugs increase the endogenous dopaminergic tone in obese insulin-resistant women with polycystic ovary syndrome. J Endocrinol 2005 ; 184: 233-239.