Structural plasticity and in vivo activity of Cas1 from the type I-F CRISPR-Cas system

Biochemical Journal

Volumn 473, Issue 8, 2016, Pages 1063-1072

  Wilkinson, Max E ^a,b   Nakatani, Yoshio ^a   Staals, Raymond H J ^a   Kieper, Sebastian N ^a,c   Opel Reading, Helen K ^a   McKenzie, Rebecca E ^a,c   Fineran, Peter C ^a   Krause, Kurt L ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^c WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Adaptation; Bacteriophages; Csy; Horizontal gene transfer; Plasmids; Protein structure

Indexed keywords

ASPARTIC ACID; CRISPR ASSOCIATED 1 PROTEIN; CRISPR ASSOCIATED 2 PROTEIN; CRISPR ASSOCIATED 3 PROTEIN; CRISPR ASSOCIATED PROTEIN; DIMER; HOMODIMER; INTEGRASE; MONOMER; UNCLASSIFIED DRUG; DEOXYRIBONUCLEASE; ESCHERICHIA COLI PROTEIN; YGBT PROTEIN, E COLI;

ALPHA HELIX; ARTICLE; BETA SHEET; CATALYSIS; CRISPR CAS SYSTEM; DNA BINDING; ENZYME ACTIVITY; ESCHERICHIA COLI; MUTAGENESIS; NONHUMAN; PECTOBACTERIUM ATROSEPTICUM; PLASTICITY; POLARIZATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; SURFACE CHARGE; WILD TYPE; X RAY CRYSTALLOGRAPHY; CHEMISTRY; CRYSTALLIZATION; METABOLISM; PECTOBACTERIUM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

CRISPR-ASSOCIATED PROTEINS; CRISPR-CAS SYSTEMS; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; ENDODEOXYRIBONUCLEASES; ESCHERICHIA COLI PROTEINS; PECTOBACTERIUM; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

EID: 84975129691     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BCJ20160078     Document Type: Article

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