Double-stranded endonuclease activity in Bacillus halodurans clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas2 protein

Journal of Biological Chemistry

Volumn 287, Issue 43, 2012, Pages 35943-35952

  Nam, Ki Hyun ^a   Ding, Fran ^a   Haitjema, Charles ^b   Huang, Qingqiu ^a   DeLisa, Matthew P ^a,b   Ke, Ailong ^a  

^a Department of Obstetrics Gynecology   (United States)

^b Cornell University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIVE IMMUNE SYSTEMS; BACILLUS HALODURANS; CONFORMATIONAL CHANGE; DIVALENT METAL ION; ENDONUCLEASE ACTIVITIES; ENDORIBONUCLEASE; GENETIC ELEMENTS; ISOTHERMAL TITRATION CALORIMETRY; PALINDROMIC; PH-DEPENDENT; PUTATIVE FUNCTIONS;

BACTERIOLOGY; CALORIMETERS; CALORIMETRY; CRYSTALLOGRAPHY; ISOTHERMS; MANGANESE; MANGANESE COMPOUNDS; METAL IONS; MUTAGENESIS; RNA; TITRATION;

PROTEINS;

ASPARTIC ACID; BACTERIAL PROTEIN; BACTERIAL PROTEIN CAS2; DOUBLE STRANDED DNA; ENDONUCLEASE; MAGNESIUM; MANGANESE; SPACER DNA; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BACILLUS; BACILLUS HALODURANS; BACTERIAL GENETICS; CATALYSIS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CONTROLLED STUDY; CRYSTALLOGRAPHY; DIMERIZATION; DNA FLANKING REGION; ENZYME ACTIVITY; GENE LOCUS; ISOTHERMAL TITRATION CALORIMETRY; MUTAGENESIS; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN MODIFICATION; PROTEIN STRUCTURE;

BACILLUS; BACTERIAL PROTEINS; DNA-BINDING PROTEINS; ENDODEOXYRIBONUCLEASES; INVERTED REPEAT SEQUENCES; MAGNESIUM; MANGANESE; MUTAGENESIS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY;

EID: 84867818484     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.382598     Document Type: Article

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