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Volumn 80, Issue 6, 2016, Pages 1131-1140

PI3K regulates BMAL1/CLOCK-mediated circadian transcription from the Dbp promoter

Author keywords

BMAL1; Circadian clock; CLOCK; Dbp; PI3K

Indexed keywords

CLOCKS;

EID: 84975128757     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1080/09168451.2015.1136885     Document Type: Article
Times cited : (19)

References (52)
  • 1
    • 0028915430 scopus 로고
    • Molecular neurobiology and genetics of circadian rhythms in mammals
    • Takahashi JS. Molecular neurobiology and genetics of circadian rhythms in mammals. Annu. Rev. Neurosci. 1995;18:531-553.
    • (1995) Annu. Rev. Neurosci. , vol.18 , pp. 531-553
    • Takahashi, J.S.1
  • 2
    • 0033593306 scopus 로고    scopus 로고
    • Molecular bases for circadian clocks
    • Dunlap, JC. Molecular bases for circadian clocks. Cell. 1999;96:271-290.
    • (1999) Cell , vol.96 , pp. 271-290
    • Dunlap, J.C.1
  • 3
    • 0032486330 scopus 로고    scopus 로고
    • Role of the CLOCK protein in the mammalian circadian mechanism
    • Gekakis N, Staknis D, Nguyen HB, et al. Role of the CLOCK protein in the mammalian circadian mechanism. Science. 1998;280:1564-1569.
    • (1998) Science , vol.280 , pp. 1564-1569
    • Gekakis, N.1    Staknis, D.2    Nguyen, H.B.3
  • 4
    • 0037194790 scopus 로고    scopus 로고
    • Coordination of circadian timing in mammals
    • Reppert SM, Weaver DR. Coordination of circadian timing in mammals. Nature. 2002;418:935-941.
    • (2002) Nature , vol.418 , pp. 935-941
    • Reppert, S.M.1    Weaver, D.R.2
  • 5
    • 0035136677 scopus 로고    scopus 로고
    • An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome
    • Toh KL, Jones CR, He Y, et al. An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome. Science. 2001;291:1040-1043.
    • (2001) Science , vol.291 , pp. 1040-1043
    • Toh, K.L.1    Jones, C.R.2    He, Y.3
  • 6
    • 33847779219 scopus 로고    scopus 로고
    • Post-translational modifications regulate the ticking of the circadian clock
    • Gallego M, Virshup DM. Post-translational modifications regulate the ticking of the circadian clock. Nat. Rev. Mol. Cell Biol. 2007;8:139-148.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 139-148
    • Gallego, M.1    Virshup, D.M.2
  • 7
    • 59649092573 scopus 로고    scopus 로고
    • Clocks go forward: Progress in the molecular genetic analysis of rhythmic behaviour
    • Nolan PM, Parsons MJ. Clocks go forward: progress in the molecular genetic analysis of rhythmic behaviour. Mamm. Genome. 2009;20:67-70
    • (2009) Mamm. Genome. , vol.20 , pp. 67-70
    • Nolan, P.M.1    Parsons, M.J.2
  • 8
    • 79955890550 scopus 로고    scopus 로고
    • Kinases and phosphatases in the mammalian circadian clock
    • Reischl S, Kramer A. Kinases and phosphatases in the mammalian circadian clock. FEBS Lett. 2011;585:1393-1399
    • (2011) FEBS Lett. , vol.585 , pp. 1393-1399
    • Reischl, S.1    Kramer, A.2
  • 9
    • 0037184977 scopus 로고    scopus 로고
    • A web of circadian pacemakers
    • Schibler U, Sassone-Corsi P. A web of circadian pacemakers. Cell. 2002;111:919-922
    • (2002) Cell , vol.111 , pp. 919-922
    • Schibler, U.1    Sassone-Corsi, P.2
  • 10
    • 4544362674 scopus 로고    scopus 로고
    • Mammalian circadian biology: Elucidating genome-wide levels of temporal organization
    • Lowrey PL, Takahashi JS. Mammalian circadian biology: elucidating genome-wide levels of temporal organization. Annu. Rev. Genomics Hum. Genet. 2004;5:407-441.
    • (2004) Annu. Rev. Genomics Hum. Genet. , vol.5 , pp. 407-441
    • Lowrey, P.L.1    Takahashi, J.S.2
  • 11
    • 34648836981 scopus 로고    scopus 로고
    • Neurons and networks in daily rhythms
    • Herzog ED. Neurons and networks in daily rhythms. Nat. Rev. Neurosci. 2007;8:790-802.
    • (2007) Nat. Rev. Neurosci. , vol.8 , pp. 790-802
    • Herzog, E.D.1
  • 12
    • 0033574429 scopus 로고    scopus 로고
    • Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase
    • Bi L, Okabe I, Bernard DJ, et al. Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase. J. Biol. Chem. 1999;274:10963-10968.
    • (1999) J. Biol. Chem. , vol.274 , pp. 10963-10968
    • Bi, L.1    Okabe, I.2    Bernard, D.J.3
  • 13
    • 0036185944 scopus 로고    scopus 로고
    • Early embryonic lethality in mice deficient in the p110beta catalytic subunit of PI3-kinase
    • Bi L, Okabe I, Bernard DJ, et al. Early embryonic lethality in mice deficient in the p110beta catalytic subunit of PI3-kinase. Mamm. Genome. 2002;13:169-172.
    • (2002) Mamm. Genome. , vol.13 , pp. 169-172
    • Bi, L.1    Okabe, I.2    Bernard, D.J.3
  • 14
    • 33744990592 scopus 로고    scopus 로고
    • Critical role for the p110α phosphoinositide-3-OH kinase in growth and metabolic regulation
    • Foukas LC, Claret M, Pearce W, Okkenhaug K, et al. Critical role for the p110α phosphoinositide-3-OH kinase in growth and metabolic regulation. Nature. 2006;441:366-370.
    • (2006) Nature , vol.441 , pp. 366-370
    • Foukas, L.C.1    Claret, M.2    Pearce, W.3    Okkenhaug, K.4
  • 15
    • 55649084906 scopus 로고    scopus 로고
    • Phosphoinositide 3-Kinase p110β activity: Key role in metabolism and mammary gland cancer but not development
    • Ciraolo E, Iezzi M, Marone R, et al. Phosphoinositide 3-Kinase p110β activity: key role in metabolism and mammary gland cancer but not development. Sci. Signal. 2008;1:ra3.
    • (2008) Sci. Signal. , vol.1 , pp. ra3
    • Ciraolo, E.1    Iezzi, M.2    Marone, R.3
  • 16
    • 49649087385 scopus 로고    scopus 로고
    • Essential roles of PI3K-p110 beta in cell growth, metabolism and tumorigenesis
    • Jia S, Liu Z, Zhang S, et al. Essential roles of PI3K-p110 beta in cell growth, metabolism and tumorigenesis. Nature. 2008;454:776-779.
    • (2008) Nature , vol.454 , pp. 776-779
    • Jia, S.1    Liu, Z.2    Zhang, S.3
  • 17
    • 77249100829 scopus 로고    scopus 로고
    • Specific roles of the p110α isoform of phosphatidylinsositol 3-kinase in hepatic insulin signaling and metabolic regulation
    • Sopasakis VR, Liu P, Suzuki R, et al. Specific roles of the p110α isoform of phosphatidylinsositol 3-kinase in hepatic insulin signaling and metabolic regulation. Cell Metab. 2010;11:220-230.
    • (2010) Cell Metab. , vol.11 , pp. 220-230
    • Sopasakis, V.R.1    Liu, P.2    Suzuki, R.3
  • 18
    • 0032143284 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase: The key switch mechanism in insulin signalling
    • Shepherd PR, Withers DJ, Siddle K. Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling. Biochem. J. 1998;333:471-490.
    • (1998) Biochem. J. , vol.333 , pp. 471-490
    • Shepherd, P.R.1    Withers, D.J.2    Siddle, K.3
  • 19
    • 16244393685 scopus 로고    scopus 로고
    • Signalling by PI3K isoforms: Insights from gene-targeted mice
    • Vanhaesebroeck B, Ali K, Bilancio A, et al. Signalling by PI3K isoforms: insights from gene-targeted mice. Trends Biochem. Sci. 2005;30:194-204.
    • (2005) Trends Biochem. Sci. , vol.30 , pp. 194-204
    • Vanhaesebroeck, B.1    Ali, K.2    Bilancio, A.3
  • 20
    • 0032497832 scopus 로고    scopus 로고
    • Structure and function of phosphoinositide 3-kinases
    • Wymann MP, Pirola L. Structure and function of phosphoinositide 3-kinases. Biochim. Biophys. Acta. 1998;1436:127-150.
    • (1998) Biochim. Biophys. Acta , vol.1436 , pp. 127-150
    • Wymann, M.P.1    Pirola, L.2
  • 21
    • 67650614337 scopus 로고    scopus 로고
    • Mini screening of kinase inhibitors affecting period-length of mammalian cellular circadian clock
    • Yagita K, Yamanaka I, Koinuma S, et al. Mini screening of kinase inhibitors affecting period-length of mammalian cellular circadian clock. Acta Histochem. Cytochem. 2009;42:89-93
    • (2009) Acta Histochem. Cytochem. , vol.42 , pp. 89-93
    • Yagita, K.1    Yamanaka, I.2    Koinuma, S.3
  • 22
    • 70349184395 scopus 로고    scopus 로고
    • A genome-wide RNAi screen for modifiers of the circadian clock in human cells
    • Zhang EE, Liu AC, Hirota T, et al. A genome-wide RNAi screen for modifiers of the circadian clock in human cells. Cell. 2009;139:199-210.
    • (2009) Cell , vol.139 , pp. 199-210
    • Zhang, E.E.1    Liu, A.C.2    Hirota, T.3
  • 23
    • 84861908435 scopus 로고    scopus 로고
    • Real-time monitoring in three-dimensional hepatocytes reveals that insulin acts as a synchronizer for liver clock
    • Yamajuku D, Inagaki T, Haruma T, et al. Real-time monitoring in three-dimensional hepatocytes reveals that insulin acts as a synchronizer for liver clock. Sci. Rep. 2012;2:439.
    • (2012) Sci. Rep. , vol.2 , pp. 439
    • Yamajuku, D.1    Inagaki, T.2    Haruma, T.3
  • 24
    • 0032511229 scopus 로고    scopus 로고
    • A serum shock induces circadian gene expression in mammalian tissue culture cells
    • Balsalobre A, Damiola F, Schibler U. A serum shock induces circadian gene expression in mammalian tissue culture cells. Cell. 1998;93:929-937.
    • (1998) Cell , vol.93 , pp. 929-937
    • Balsalobre, A.1    Damiola, F.2    Schibler, U.3
  • 25
    • 0036209094 scopus 로고    scopus 로고
    • CREB required for the stability of new and reactivated fear memories
    • Kida S, Josselyn SA, Peña de Ortiz S, et al. CREB required for the stability of new and reactivated fear memories. Nat. Neurosci. 2002;5:348-355.
    • (2002) Nat. Neurosci. , vol.5 , pp. 348-355
    • Kida, S.1    Josselyn, S.A.2    Peña De Ortiz, S.3
  • 26
    • 33645088922 scopus 로고    scopus 로고
    • Tight regulation of transgene expression by tetracycline-dependent activator and repressor in brain
    • Uchida S, Sakai S, Furuichi T, et al. Tight regulation of transgene expression by tetracycline-dependent activator and repressor in brain. Genes Brain Behav. 2006;5:96-106.
    • (2006) Genes Brain Behav , vol.5 , pp. 96-106
    • Uchida, S.1    Sakai, S.2    Furuichi, T.3
  • 27
    • 54049107769 scopus 로고    scopus 로고
    • Upregulation of calcium/calmodulin-dependent protein kinase IV improves memory formation and rescues memory loss with aging
    • Fukushima H, Maeda R, Suzuki R, et al. Upregulation of calcium/calmodulin-dependent protein kinase IV improves memory formation and rescues memory loss with aging. J. Neurosci. 2008;28:9910-9919.
    • (2008) J. Neurosci. , vol.28 , pp. 9910-9919
    • Fukushima, H.1    Maeda, R.2    Suzuki, R.3
  • 28
    • 65449154047 scopus 로고    scopus 로고
    • Transgenic up-regulation of alpha-CaMKII in forebrain leads to increased anxiety-like behaviors and aggression
    • Hasegawa S, Furuichi T, Yoshida T, et al. Transgenic up-regulation of alpha-CaMKII in forebrain leads to increased anxiety-like behaviors and aggression. Mol. Brain. 2009;2:6.
    • (2009) Mol. Brain. , vol.2 , pp. 6
    • Hasegawa, S.1    Furuichi, T.2    Yoshida, T.3
  • 29
    • 79959306968 scopus 로고    scopus 로고
    • Upregulation of CREB-mediated transcription enhances both short- and long-term memory
    • Suzuki A, Fukushima H, Mukawa T, et al. Upregulation of CREB-mediated transcription enhances both short- and long-term memory. J. Neurosci. 2011;31:8786-8802.
    • (2011) J. Neurosci. , vol.31 , pp. 8786-8802
    • Suzuki, A.1    Fukushima, H.2    Mukawa, T.3
  • 30
    • 84856602346 scopus 로고    scopus 로고
    • Dysfunction of the RAR/RXR signaling pathway in the forebrain impairs hippocampal memory and synaptic plasticity
    • Nomoto M, Takeda Y, Uchida S, et al. Dysfunction of the RAR/RXR signaling pathway in the forebrain impairs hippocampal memory and synaptic plasticity. Mol. Brain. 2012;5:8.
    • (2012) Mol. Brain. , vol.5 , pp. 8
    • Nomoto, M.1    Takeda, Y.2    Uchida, S.3
  • 31
    • 72449210271 scopus 로고    scopus 로고
    • CBP/p300 is a cell type-specific modulator of CLOCK/BMAL1-mediated transcription
    • Hosoda H, Kato K, Asano H, et al. CBP/p300 is a cell type-specific modulator of CLOCK/BMAL1-mediated transcription. Mol. Brain. 2009;2:34.
    • (2009) Mol. Brain. , vol.2 , pp. 34
    • Hosoda, H.1    Kato, K.2    Asano, H.3
  • 32
    • 26944474790 scopus 로고    scopus 로고
    • Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatum
    • Kumar A, Choi KH, Renthal W, et al. Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatum. Neuron. 2005;48:303-314.
    • (2005) Neuron. , vol.48 , pp. 303-314
    • Kumar, A.1    Choi, K.H.2    Renthal, W.3
  • 33
    • 33645357786 scopus 로고    scopus 로고
    • Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action
    • Tsankova NM, Berton O, Renthal W, et al. Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nat. Neurosci. 2006;9:519-525.
    • (2006) Nat. Neurosci. , vol.9 , pp. 519-525
    • Tsankova, N.M.1    Berton, O.2    Renthal, W.3
  • 34
    • 65549123471 scopus 로고    scopus 로고
    • HDAC2 negatively regulates memory formation and synaptic plasticity
    • Guan JS, Haggarty SJ, Giacometti E, et al. HDAC2 negatively regulates memory formation and synaptic plasticity. Nature. 2009;459:55-60.
    • (2009) Nature , vol.459 , pp. 55-60
    • Guan, J.S.1    Haggarty, S.J.2    Giacometti, E.3
  • 35
    • 78751689075 scopus 로고    scopus 로고
    • Epigenetic status of Gdnf in the ventral striatum determines susceptibility and adaptation to daily stressful events
    • Uchida S, Hara K, Kobayashi A, et al. Epigenetic status of Gdnf in the ventral striatum determines susceptibility and adaptation to daily stressful events. Neuron. 2011;69:359-372.
    • (2011) Neuron. , vol.69 , pp. 359-372
    • Uchida, S.1    Hara, K.2    Kobayashi, A.3
  • 36
    • 4143088113 scopus 로고    scopus 로고
    • A BMAL1 mutant with arginine 91 substituted with alanine acts as a dominant negative inhibitor
    • Hosoda H, Motohashi J, Kato H, et al. A BMAL1 mutant with arginine 91 substituted with alanine acts as a dominant negative inhibitor. Gene. 2004;338:235-241.
    • (2004) Gene. , vol.338 , pp. 235-241
    • Hosoda, H.1    Motohashi, J.2    Kato, H.3
  • 37
    • 33644617485 scopus 로고    scopus 로고
    • Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions
    • Ripperger JA, Schibler U. Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions. Nat. Genet. 2006;38:369-374.
    • (2006) Nat. Genet. , vol.38 , pp. 369-374
    • Ripperger, J.A.1    Schibler, U.2
  • 38
    • 84868097990 scopus 로고    scopus 로고
    • Circadian Dbp transcription relies on highly dynamic BMAL1-CLOCK interaction with E boxes and requires the proteasome
    • Stratmann M, Suter DM, Molina N, et al. Circadian Dbp transcription relies on highly dynamic BMAL1-CLOCK interaction with E boxes and requires the proteasome. Mol. Cell. 2012;48:277-287.
    • (2012) Mol. Cell. , vol.48 , pp. 277-287
    • Stratmann, M.1    Suter, D.M.2    Molina, N.3
  • 41
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • Cross DA, Alessi DR, Cohen P, et al. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature. 1995;378:785-789.
    • (1995) Nature. , vol.378 , pp. 785-789
    • Cross, D.A.1    Alessi, D.R.2    Cohen, P.3
  • 42
    • 0038538430 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase-dependent activation of Rac
    • Welch HC, Coadwell WJ, Stephens LR, et al. Phosphoinositide 3-kinase-dependent activation of Rac. FEBS Lett. 2003;546:93-97.
    • (2003) FEBS Lett. , vol.546 , pp. 93-97
    • Welch, H.C.1    Coadwell, W.J.2    Stephens, L.R.3
  • 43
    • 0029070887 scopus 로고
    • Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs
    • Minden A, Lin A, Claret FX, et al. Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs. Cell. 1995;81:1147-1157.
    • (1995) Cell. , vol.81 , pp. 1147-1157
    • Minden, A.1    Lin, A.2    Claret, F.X.3
  • 44
    • 0037053314 scopus 로고    scopus 로고
    • The circadian regulatory proteins BMAL1 and cryptochromes are substrates of casein kinase I&epsi
    • Eide EJ, Vielhaber EL, Hinz WA, et al. The circadian regulatory proteins BMAL1 and cryptochromes are substrates of casein kinase I&epsi. J. Biol. Chem. 2002;277:17248-17254.
    • (2002) J. Biol. Chem. , vol.277 , pp. 17248-17254
    • Eide, E.J.1    Vielhaber, E.L.2    Hinz, W.A.3
  • 45
    • 23944470712 scopus 로고    scopus 로고
    • Circadian clock control by SUMOylation of BMAL1
    • Cardone L, Hirayama J, Giordano F, et al. Circadian clock control by SUMOylation of BMAL1. Science. 2005;309:1390-1394.
    • (2005) Science , vol.309 , pp. 1390-1394
    • Cardone, L.1    Hirayama, J.2    Giordano, F.3
  • 46
    • 64049083872 scopus 로고    scopus 로고
    • CK2α phosphorylates BMAL1 to regulate the mammalian clock
    • Tamaru T, Hirayama J, Isojima Y, et al. CK2α phosphorylates BMAL1 to regulate the mammalian clock. Nat. Struct. Mol. Biol. 2009;16:446-448.
    • (2009) Nat. Struct. Mol. Biol. , vol.16 , pp. 446-448
    • Tamaru, T.1    Hirayama, J.2    Isojima, Y.3
  • 47
    • 67650094963 scopus 로고    scopus 로고
    • Roles of CLOCK phosphorylation in suppression of E-box-dependent transcription
    • Yoshitane H, Takao T, Satomi Y, et al. Roles of CLOCK phosphorylation in suppression of E-box-dependent transcription. Mol. Cell Biol. 2009;29:3675-3686.
    • (2009) Mol. Cell Biol. , vol.29 , pp. 3675-3686
    • Yoshitane, H.1    Takao, T.2    Satomi, Y.3
  • 48
    • 77649144065 scopus 로고    scopus 로고
    • Regulation of BMAL1 protein stability and circadian function by GSK3β-mediated phosphorylation
    • Sahar S, Zocchi L, Kinoshita C, et al. Regulation of BMAL1 protein stability and circadian function by GSK3β-mediated phosphorylation. PLoS One. 2010;5:e8561.
    • (2010) PLoS One , vol.5
    • Sahar, S.1    Zocchi, L.2    Kinoshita, C.3
  • 49
    • 84860489069 scopus 로고    scopus 로고
    • JNK regulates the photic response of the mammalian circadian clock
    • Yoshitane H, Honma S, Imamura K, et al. JNK regulates the photic response of the mammalian circadian clock. EMBO Rep. 2012;13:455-461.
    • (2012) EMBO Rep. , vol.13 , pp. 455-461
    • Yoshitane, H.1    Honma, S.2    Imamura, K.3
  • 50
    • 0025319528 scopus 로고
    • DBP, a liver-enriched transcriptional activator, is expressed late in ontogeny and its tissue specificity is determined posttranscriptionally
    • Mueller CR, Maire P, Schibler U. DBP, a liver-enriched transcriptional activator, is expressed late in ontogeny and its tissue specificity is determined posttranscriptionally. Cell. 1990;61:279-291.
    • (1990) Cell , vol.61 , pp. 279-291
    • Mueller, C.R.1    Maire, P.2    Schibler, U.3
  • 51
    • 0034122094 scopus 로고    scopus 로고
    • Role of DBP in the Circadian Oscillatory Mechanism
    • Yamaguchi S, Mitsui S, Yan L, et al. Role of DBP in the Circadian Oscillatory Mechanism. Mol. Cell Biol. 2000;20:4773-4781.
    • (2000) Mol. Cell Biol. , vol.20 , pp. 4773-4781
    • Yamaguchi, S.1    Mitsui, S.2    Yan, L.3
  • 52
    • 79960357928 scopus 로고    scopus 로고
    • Cellular DBP and E4BP4 proteins are critical for determining the period length of the circadian oscillator
    • Yamajuku D, Shibata Y, Kitazawa M, et al. Cellular DBP and E4BP4 proteins are critical for determining the period length of the circadian oscillator. FEBS Lett. 2011;585:2217-2222.
    • (2011) FEBS Lett. , vol.585 , pp. 2217-2222
    • Yamajuku, D.1    Shibata, Y.2    Kitazawa, M.3


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