Real-time monitoring in three-dimensional hepatocytes reveals that insulin acts as a synchronizer for liver clock

Scientific Reports

Volumn 2, Issue , 2012, Pages

  Yamajuku, Daisuke ^a   Inagaki, Takahiko ^b   Haruma, Tomonori ^b   Okubo, Shingo ^b   Kataoka, Yutaro ^b   Kobayashi, Satoru ^b   Ikegami, Keisuke ^b   Laurent, Thomas ^b   Kojima, Tomoko ^a   Noutomi, Keiji ^a   Hashimoto, Seiichi ^a   Oda, Hiroaki ^b  

^a ASTELLAS PHARMA INC   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDIABETIC AGENT; CIRCADIAN RHYTHM SIGNALING PROTEIN; INSULIN; LUCIFERASE;

ANIMAL; ARTICLE; BIOLOGICAL RHYTHM; CELL CULTURE; CELL LINE; CIRCADIAN RHYTHM; CULTURE TECHNIQUE; CYTOLOGY; DNA MICROARRAY; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETICS; LIVER; LIVER CELL; MALE; METABOLISM; NORTHERN BLOTTING; PATHOPHYSIOLOGY; PHYSIOLOGY; RAT; TRANSGENIC RAT; WISTAR RAT;

ANIMALS; BIOLOGICAL CLOCKS; BLOTTING, NORTHERN; CELL CULTURE TECHNIQUES; CELL LINE; CELLS, CULTURED; CIRCADIAN RHYTHM; DIABETES MELLITUS, EXPERIMENTAL; GENE EXPRESSION; GENE EXPRESSION PROFILING; HEPATOCYTES; HYPOGLYCEMIC AGENTS; INSULIN; LIVER; LUCIFERASES; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PERIOD CIRCADIAN PROTEINS; RATS; RATS, TRANSGENIC; RATS, WISTAR;

EID: 84861908435     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep00439     Document Type: Article

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