Transcriptome analysis of piperlongumine-treated human pancreatic cancer cells reveals involvement of oxidative stress and endoplasmic reticulum stress pathways

Journal of Medicinal Food

Volumn 19, Issue 6, 2016, Pages 578-585

  Dhillon, Harsharan ^a   Mamidi, Sujan ^a   Mcclean, Phillip ^a   Reindl, Katie M ^a  

^a NORTH DAKOTA STATE UNIVERSITY   (United States)

Author keywords

ER stress; oxidative stress; pancreatic cancer; piperlongumine; RNA sequencing; transcriptomics

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ANTINEOPLASTIC ALKALOID; ASPARTATE AMMONIA LIGASE; CYTOCHROME C; HEME OXYGENASE 1; HERBACEOUS AGENT; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PIPERLONGUMINE; PROTEIN IRE1; TRANSCRIPTOME; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; 1,3 DIOXOLANE DERIVATIVE; PIPERLONGUMININE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN GENOME; OXIDATIVE STRESS; PANCREATIC CANCER CELL LINE; PIPER LONGUM; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN FUNCTION; RNA SEQUENCE; TRANSCRIPTOMICS; UNFOLDED PROTEIN RESPONSE; WESTERN BLOTTING; APOPTOSIS; DRUG EFFECTS; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; PANCREATIC NEOPLASMS; PATHOPHYSIOLOGY; TUMOR CELL LINE;

APOPTOSIS; CELL LINE, TUMOR; DIOXOLANES; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION PROFILING; HUMANS; OXIDATIVE STRESS; PANCREATIC NEOPLASMS;

EID: 84974555985     PISSN: 1096620X     EISSN: 15577600     Source Type: Journal    
DOI: 10.1089/jmf.2015.0152     Document Type: Article

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