-
1
-
-
34249778657
-
A semisynthetic epitope for kinase substrates
-
Allen, J.J., M. Li, C.S. Brinkworth, J.L. Paulson, D. Wang, A. Hübner, W.H. Chou, R.J. Davis, A.L. Burlingame, R.O. Messing, et al. 2007. A semisynthetic epitope for kinase substrates. Nat. Methods. 4:511-516. http://dx.doi.org/10.1038/nmeth1048
-
(2007)
Nat. Methods
, vol.4
, pp. 511-516
-
-
Allen, J.J.1
Li, M.2
Brinkworth, C.S.3
Paulson, J.L.4
Wang, D.5
Hübner, A.6
Chou, W.H.7
Davis, R.J.8
Burlingame, A.L.9
Messing, R.O.10
-
2
-
-
52649114829
-
Sprouty2- mediated inhibition of fibroblast growth factor signaling is modulated by the protein kinase DYRK1A
-
Aranda, S., M. Alvarez, S. Turró, A. Laguna, and S. de la Luna. 2008. Sprouty2- mediated inhibition of fibroblast growth factor signaling is modulated by the protein kinase DYRK1A. Mol. Cell. Biol. 28:5899-5911. http:// dx.doi.org/10.1128/MCB.00394-08
-
(2008)
Mol. Cell. Biol
, vol.28
, pp. 5899-5911
-
-
Aranda, S.1
Alvarez, M.2
Turró, S.3
Laguna, A.4
de la Luna, S.5
-
3
-
-
84903771640
-
DYRK1A promotes dopaminergic neuron survival in the developing brain and in a mouse model of Parkinson's disease
-
Barallobre, M.J., C. Perier, J. Bové, A. Laguna, J.M. Delabar, M. Vila, and M.L. Arbonés. 2014. DYRK1A promotes dopaminergic neuron survival in the developing brain and in a mouse model of Parkinson's disease. Cell Death Dis. 5:e1289. http://dx.doi.org/10.1038/cddis.2014 .253
-
(2014)
Cell Death Dis
, vol.5
-
-
Barallobre, M.J.1
Perier, C.2
Bové, J.3
Laguna, A.4
Delabar, J.M.5
Vila, M.6
Arbonés, M.L.7
-
4
-
-
72049125085
-
Lysine 269 is essential for cyclin D1 ubiquitylation by the SCF(Fbx4/alphaB-crystallin) ligase and subsequent proteasome-dependent degradation
-
Barbash, O., E. Egan, L.L. Pontano, J. Kosak, and J.A. Diehl. 2009. Lysine 269 is essential for cyclin D1 ubiquitylation by the SCF(Fbx4/alphaB-crystallin) ligase and subsequent proteasome-dependent degradation. Oncogene. 28:4317-4325. http://dx.doi.org/10.1038/onc.2009.287
-
(2009)
Oncogene
, vol.28
, pp. 4317-4325
-
-
Barbash, O.1
Egan, E.2
Pontano, L.L.3
Kosak, J.4
Diehl, J.A.5
-
5
-
-
84866754278
-
Emerging role of DYRK family protein kinases as regulators of protein stability in cell cycle control
-
Becker, W. 2012. Emerging role of DYRK family protein kinases as regulators of protein stability in cell cycle control. Cell Cycle. 11:3389-3394. http://dx.doi.org/10.4161/cc.21404
-
(2012)
Cell Cycle
, vol.11
, pp. 3389-3394
-
-
Becker, W.1
-
6
-
-
6344240450
-
P38SAPK2 phosphorylates cyclin D3 at Thr-283 and targets it for proteasomal degradation
-
Casanovas, O., M. Jaumot, A.B. Paules, N. Agell, and O. Bachs. 2004. P38SAPK2 phosphorylates cyclin D3 at Thr-283 and targets it for proteasomal degradation. Oncogene. 23:7537-7544. http://dx.doi.org/10.1038/sj .onc.1208040
-
(2004)
Oncogene
, vol.23
, pp. 7537-7544
-
-
Casanovas, O.1
Jaumot, M.2
Paules, A.B.3
Agell, N.4
Bachs, O.5
-
7
-
-
84885334501
-
Dosage of Dyrk1a shifts cells within a p21-cyclin D1 signaling map to control the decision to enter the cell cycle
-
Chen, J.Y., J.R. Lin, F.C. Tsai, and T. Meyer. 2013. Dosage of Dyrk1a shifts cells within a p21-cyclin D1 signaling map to control the decision to enter the cell cycle. Mol. Cell. 52:87-100. http://dx.doi.org/10 .1016/j.molcel.2013.09.009
-
(2013)
Mol. Cell
, vol.52
, pp. 87-100
-
-
Chen, J.Y.1
Lin, J.R.2
Tsai, F.C.3
Meyer, T.4
-
8
-
-
84903624810
-
Activity-dependent facilitation of Synaptojanin and synaptic vesicle recycling by the Minibrain kinase
-
Chen, C.K., C. Bregere, J. Paluch, J.F. Lu, D.K. Dickman, and K.T. Chang. 2014. Activity-dependent facilitation of Synaptojanin and synaptic vesicle recycling by the Minibrain kinase. Nat. Commun. 5:4246. http://dx.doi .org/10.1038/ncomms5246
-
(2014)
Nat. Commun
, vol.5
, pp. 4246
-
-
Chen, C.K.1
Bregere, C.2
Paluch, J.3
Lu, J.F.4
Dickman, D.K.5
Chang, K.T.6
-
9
-
-
84893685103
-
Orchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signalling
-
Clark, M.R., M. Mandal, K. Ochiai, and H. Singh. 2014. Orchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signalling. Nat. Rev. Immunol. 14:69-80. http://dx.doi.org/10 .1038/nri3570
-
(2014)
Nat. Rev. Immunol
, vol.14
, pp. 69-80
-
-
Clark, M.R.1
Mandal, M.2
Ochiai, K.3
Singh, H.4
-
10
-
-
33645964321
-
A unique function for cyclin D3 in early B cell development
-
Cooper, A.B., C.M. Sawai, E. Sicinska, S.E. Powers, P. Sicinski, M.R. Clark, and I. Aifantis. 2006. A unique function for cyclin D3 in early B cell development. Nat. Immunol. 7:489-497. http://dx.doi.org/10.1038/ni1324
-
(2006)
Nat. Immunol
, vol.7
, pp. 489-497
-
-
Cooper, A.B.1
Sawai, C.M.2
Sicinska, E.3
Powers, S.E.4
Sicinski, P.5
Clark, M.R.6
Aifantis, I.7
-
11
-
-
33645531727
-
The protein kinase DYRK1A phosphorylates the splicing factor SF3b1/SAP155 at Thr434, a novel in vivo phosphorylation site
-
de Graaf, K., H. Czajkowska, S. Rottmann, L.C. Packman, R. Lilischkis, B. Lüscher, and W. Becker. 2006. The protein kinase DYRK1A phosphorylates the splicing factor SF3b1/SAP155 at Thr434, a novel in vivo phosphorylation site. BMC Biochem. 7:7. http://dx.doi.org/10 .1186/1471-2091-7-7
-
(2006)
BMC Biochem
, vol.7
, pp. 7
-
-
de Graaf, K.1
Czajkowska, H.2
Rottmann, S.3
Packman, L.C.4
Lilischkis, R.5
Lüscher, B.6
Becker, W.7
-
12
-
-
84924902637
-
Chromatin-wide profiling of DYRK1A reveals a role as a gene-specific RNA polymerase II CTD kinase
-
Di Vona, C., D. Bezdan, A.B. Islam, E. Salichs, N. López-Bigas, S. Ossowski, and S. de la Luna. 2015. Chromatin-wide profiling of DYRK1A reveals a role as a gene-specific RNA polymerase II CTD kinase. Mol. Cell. 57:506-520. http://dx.doi.org/10.1016/j.molcel.2014.12.026
-
(2015)
Mol. Cell
, vol.57
, pp. 506-520
-
-
Di Vona, C.1
Bezdan, D.2
Islam, A.B.3
Salichs, E.4
López-Bigas, N.5
Ossowski, S.6
de la Luna, S.7
-
13
-
-
84870835308
-
Gene dosage-dependent association of DYRK1A with the cytoskeleton in the brain and lymphocytes of down syndrome patients
-
Dowjat, K., T. Adayev, W. Kaczmarski, J. Wegiel, and Y.W. Hwang. 2012. Gene dosage-dependent association of DYRK1A with the cytoskeleton in the brain and lymphocytes of down syndrome patients. J. Neuropathol. Exp. Neurol. 71:1100-1112. http://dx.doi.org/10.1097/ NEN.0b013e31827733c8
-
(2012)
J. Neuropathol. Exp. Neurol
, vol.71
, pp. 1100-1112
-
-
Dowjat, K.1
Adayev, T.2
Kaczmarski, W.3
Wegiel, J.4
Hwang, Y.W.5
-
14
-
-
84901292458
-
Loss of the mammalian DREAM complex deregulates chondrocyte proliferation
-
Forristal, C., S.A. Henley, J.I. MacDonald, J.R. Bush, C. Ort, D.T. Passos, S. Talluri, C.A. Ishak, M.J. Thwaites, C.J. Norley, et al. 2014. Loss of the mammalian DREAM complex deregulates chondrocyte proliferation. Mol. Cell. Biol. 34:2221-2234. http://dx.doi.org/10.1128/MCB .01523-13
-
(2014)
Mol. Cell. Biol
, vol.34
, pp. 2221-2234
-
-
Forristal, C.1
Henley, S.A.2
MacDonald, J.I.3
Bush, J.R.4
Ort, C.5
Passos, D.T.6
Talluri, S.7
Ishak, C.A.8
Thwaites, M.J.9
Norley, C.J.10
-
15
-
-
84907494554
-
Design and synthesis of thiazolo[5,4-f]quinazolines as DYRK1A inhibitors, part I
-
Foucourt, A., D. Hédou, C. Dubouilh-Benard, L. Désiré, A.S. Casagrande, B. Leblond, N. Loäec, L. Meijer, and T. Besson. 2014a. Design and synthesis of thiazolo[5,4-f]quinazolines as DYRK1A inhibitors, part I. Molecules. 19:15546-15571. http://dx.doi.org/10.3390/molecules191015546
-
(2014)
Molecules
, vol.19
, pp. 15546-15571
-
-
Foucourt, A.1
Hédou, D.2
Dubouilh-Benard, C.3
Désiré, L.4
Casagrande, A.S.5
Leblond, B.6
Loäec, N.7
Meijer, L.8
Besson, T.9
-
16
-
-
84907494556
-
Design and synthesis of thiazolo[5,4-f]quinazolines as DYRK1A inhibitors, part II
-
Foucourt, A., D. Hédou, C. Dubouilh-Benard, A. Girard, T. Taverne, A.S. Casagrande, L. Désiré, B. Leblond, and T. Besson. 2014b. Design and synthesis of thiazolo[5,4-f]quinazolines as DYRK1A inhibitors, part II. Molecules. 19:15411-15439. http://dx.doi.org/10.3390/molecules191015411
-
(2014)
Molecules
, vol.19
, pp. 15411-15439
-
-
Foucourt, A.1
Hédou, D.2
Dubouilh-Benard, C.3
Girard, A.4
Taverne, T.5
Casagrande, A.S.6
Désiré, L.7
Leblond, B.8
Besson, T.9
-
17
-
-
2342605448
-
Overexpression of the human MNB/DYRK1A gene induces formation of multinucleate cells through overduplication of the centrosome
-
Funakoshi, E., T. Hori, T. Haraguchi, Y. Hiraoka, J. Kudoh, N. Shimizu, and F. Ito. 2003. Overexpression of the human MNB/DYRK1A gene induces formation of multinucleate cells through overduplication of the centrosome. BMC Cell Biol. 4:12. http://dx.doi.org/10.1186/1471- 2121-4-12
-
(2003)
BMC Cell Biol
, vol.4
, pp. 12
-
-
Funakoshi, E.1
Hori, T.2
Haraguchi, T.3
Hiraoka, Y.4
Kudoh, J.5
Shimizu, N.6
Ito, F.7
-
18
-
-
77951225449
-
DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1
-
Guo, X., J.G. Williams, T.T. Schug, and X. Li. 2010. DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1. J. Biol. Chem. 285:13223-13232. http://dx.doi.org/10.1074/ jbc.M110.102574
-
(2010)
J. Biol. Chem
, vol.285
, pp. 13223-13232
-
-
Guo, X.1
Williams, J.G.2
Schug, T.T.3
Li, X.4
-
19
-
-
33646559053
-
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT
-
Gwack, Y., S. Sharma, J. Nardone, B. Tanasa, A. Iuga, S. Srikanth, H. Okamura, D. Bolton, S. Feske, P.G. Hogan, and A. Rao. 2006. A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT. Nature. 441:646-650. http://dx.doi.org/ 10.1038/nature04631
-
(2006)
Nature
, vol.441
, pp. 646-650
-
-
Gwack, Y.1
Sharma, S.2
Nardone, J.3
Tanasa, B.4
Iuga, A.5
Srikanth, S.6
Okamura, H.7
Bolton, D.8
Feske, S.9
Hogan, P.G.10
Rao, A.11
-
20
-
-
79957648087
-
Transient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling
-
Hämmerle, B., E. Ulin, J. Guimera, W. Becker, F. Guillemot, and F.J. Tejedor. 2011. Transient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling. Development. 138:2543- 2554. http://dx.doi.org/10.1242/dev.066167
-
(2011)
Development
, vol.138
, pp. 2543- 2554
-
-
Hämmerle, B.1
Ulin, E.2
Guimera, J.3
Becker, W.4
Guillemot, F.5
Tejedor, F.J.6
-
21
-
-
0029556979
-
T-cell-specific deletion of a polypeptide N-acetylgalactosaminyl-transferase gene by site-directed recombination
-
Hennet, T., F.K. Hagen, L.A. Tabak, and J.D. Marth. 1995. T-cell-specific deletion of a polypeptide N-acetylgalactosaminyl-transferase gene by site-directed recombination. Proc. Natl. Acad. Sci. USA. 92:12070-12074. http://dx.doi.org/10.1073/pnas.92.26.12070
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 12070-12074
-
-
Hennet, T.1
Hagen, F.K.2
Tabak, L.A.3
Marth, J.D.4
-
22
-
-
33748774926
-
Testing gene function early in the B cell lineage in mb1-cre mice
-
Hobeika, E., S. Thiemann, B. Storch, H. Jumaa, P.J. Nielsen, R. Pelanda, and M. Reth. 2006. Testing gene function early in the B cell lineage in mb1-cre mice. Proc. Natl. Acad. Sci. USA. 103:13789-13794. http:// dx.doi.org/10.1073/pnas.0605944103
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 13789-13794
-
-
Hobeika, E.1
Thiemann, S.2
Storch, B.3
Jumaa, H.4
Nielsen, P.J.5
Pelanda, R.6
Reth, M.7
-
23
-
-
0036143404
-
Changes in gene expression profiles in developing B cells of murine bone marrow
-
Hoffmann, R., T. Seidl, M. Neeb, A. Rolink, and F. Melchers. 2002. Changes in gene expression profiles in developing B cells of murine bone marrow. Genome Res. 12:98-111. http://dx.doi.org/10.1101/gr.201501
-
(2002)
Genome Res
, vol.12
, pp. 98-111
-
-
Hoffmann, R.1
Seidl, T.2
Neeb, M.3
Rolink, A.4
Melchers, F.5
-
24
-
-
34547589578
-
DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists
-
Web Server
-
Huang, D.W., B.T. Sherman, Q. Tan, J. Kir, D. Liu, D. Bryant, Y. Guo, R. Stephens, M.W. Baseler, H.C. Lane, and R.A. Lempicki. 2007. DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists. Nucleic Acids Res. 35(Web Server):W169-75. http://dx.doi.org/10.1093/nar/ gkm415
-
(2007)
Nucleic Acids Res
, vol.35
, pp. W169-W175
-
-
Huang, D.W.1
Sherman, B.T.2
Tan, Q.3
Kir, J.4
Liu, D.5
Bryant, D.6
Guo, Y.7
Stephens, R.8
Baseler, M.W.9
Lane, H.C.10
Lempicki, R.A.11
-
25
-
-
84878341989
-
Acute lymphoblastic leukaemia
-
Inaba, H., M. Greaves, and C.G. Mullighan. 2013. Acute lymphoblastic leukaemia. Lancet. 381:1943-1955. http://dx.doi.org/10.1016/S0140- 6736(12)62187-4
-
(2013)
Lancet
, vol.381
, pp. 1943-1955
-
-
Inaba, H.1
Greaves, M.2
Mullighan, C.G.3
-
26
-
-
40249112989
-
Regulation of immunoglobulin lightchain recombination by the transcription factor IRF-4 and the attenuation of interleukin-7 signaling
-
Johnson, K., T. Hashimshony, C.M. Sawai, J.M. Pongubala, J.A. Skok, I. Aifantis, and H. Singh. 2008. Regulation of immunoglobulin lightchain recombination by the transcription factor IRF-4 and the attenuation of interleukin-7 signaling. Immunity. 28:335-345. http://dx.doi .org/10.1016/j.immuni.2007.12.019
-
(2008)
Immunity
, vol.28
, pp. 335-345
-
-
Johnson, K.1
Hashimshony, T.2
Sawai, C.M.3
Pongubala, J.M.4
Skok, J.A.5
Aifantis, I.6
Singh, H.7
-
27
-
-
84896559398
-
Triplication of DYRK1A causes retinal structural and functional alterations in Down syndrome
-
Laguna, A., M.J. Barallobre, M.A. Marchena, C. Mateus, E. Ramírez, C. Martínez-Cue, J.M. Delabar, M. Castelo-Branco, P. de la Villa, and M.L. Arbonés. 2013. Triplication of DYRK1A causes retinal structural and functional alterations in Down syndrome. Hum. Mol. Genet. 22:2775-2784. http://dx.doi.org/10.1093/hmg/ddt125
-
(2013)
Hum. Mol. Genet
, vol.22
, pp. 2775-2784
-
-
Laguna, A.1
Barallobre, M.J.2
Marchena, M.A.3
Mateus, C.4
Ramírez, E.5
Martínez-Cue, C.6
Delabar, J.M.7
Castelo-Branco, M.8
de la Villa, P.9
Arbonés, M.L.10
-
28
-
-
33646146190
-
Degradation of cyclin D3 independent of Thr-283 phosphorylation
-
Låhne, H.U., M.M. Kloster, S. Lefdal, H.K. Blomhoff, and S. Naderi. 2006. Degradation of cyclin D3 independent of Thr-283 phosphorylation. Oncogene. 25:2468-2476. http://dx.doi.org/10.1038/sj.onc .1209278
-
(2006)
Oncogene
, vol.25
, pp. 2468-2476
-
-
Låhne, H.U.1
Kloster, M.M.2
Lefdal, S.3
Blomhoff, H.K.4
Naderi, S.5
-
29
-
-
0027362625
-
The retinoblastoma protein binds to a family of E2F transcription factors
-
Lees, J.A., M. Saito, M. Vidal, M. Valentine, T. Look, E. Harlow, N. Dyson, and K. Helin. 1993. The retinoblastoma protein binds to a family of E2F transcription factors. Mol. Cell. Biol. 13:7813-7825.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 7813-7825
-
-
Lees, J.A.1
Saito, M.2
Vidal, M.3
Valentine, M.4
Look, T.5
Harlow, E.6
Dyson, N.7
Helin, K.8
-
30
-
-
79955432610
-
DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly
-
Litovchick, L., L.A. Florens, S.K. Swanson, M.P. Washburn, and J.A. DeCaprio. 2011. DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly. Genes Dev. 25:801-813. http://dx.doi.org/10.1101/gad.2034211
-
(2011)
Genes Dev
, vol.25
, pp. 801-813
-
-
Litovchick, L.1
Florens, L.A.2
Swanson, S.K.3
Washburn, M.P.4
DeCaprio, J.A.5
-
31
-
-
0037352031
-
A highly efficient recombineering- based method for generating conditional knockout mutations
-
Liu, P., N.A. Jenkins, and N.G. Copeland. 2003. A highly efficient recombineering- based method for generating conditional knockout mutations. Genome Res. 13:476-484. http://dx.doi.org/10.1101/gr.749203
-
(2003)
Genome Res
, vol.13
, pp. 476-484
-
-
Liu, P.1
Jenkins, N.A.2
Copeland, N.G.3
-
32
-
-
84902438530
-
Tumor suppressor DYRK1A effects on proliferation and chemoresistance of AML cells by downregulating c-Myc
-
Liu, Q., N. Liu, S. Zang, H. Liu, P. Wang, C. Ji, and X. Sun. 2014. Tumor suppressor DYRK1A effects on proliferation and chemoresistance of AML cells by downregulating c-Myc. PLoS ONE. 9:e98853. http:// dx.doi.org/10.1371/journal.pone.0098853
-
(2014)
PLoS ONE
, vol.9
-
-
Liu, Q.1
Liu, N.2
Zang, S.3
Liu, H.4
Wang, P.5
Ji, C.6
Sun, X.7
-
33
-
-
42149173126
-
Characterization of the human DYRK1A promoter and its regulation by the transcription factor E2F1
-
Maenz, B., P. Hekerman, E.M. Vela, J. Galceran, and W. Becker. 2008. Characterization of the human DYRK1A promoter and its regulation by the transcription factor E2F1. BMC Mol. Biol. 9:30. http://dx.doi .org/10.1186/1471-2199-9-30
-
(2008)
BMC Mol. Biol
, vol.9
, pp. 30
-
-
Maenz, B.1
Hekerman, P.2
Vela, E.M.3
Galceran, J.4
Becker, W.5
-
34
-
-
84857814609
-
Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome
-
Malinge, S., M. Bliss-Moreau, G. Kirsammer, L. Diebold, T. Chlon, S. Gurbuxani, and J.D. Crispino. 2012. Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome. J. Clin. Invest. 122:948-962. http:// dx.doi.org/10.1172/JCI60455
-
(2012)
J. Clin. Invest
, vol.122
, pp. 948-962
-
-
Malinge, S.1
Bliss-Moreau, M.2
Kirsammer, G.3
Diebold, L.4
Chlon, T.5
Gurbuxani, S.6
Crispino, J.D.7
-
35
-
-
70349445270
-
Ras orchestrates exit from the cell cycle and lightchain recombination during early B cell development
-
Mandal, M., S.E. Powers, K. Ochiai, K. Georgopoulos, B.L. Kee, H. Singh, and M.R. Clark. 2009. Ras orchestrates exit from the cell cycle and lightchain recombination during early B cell development. Nat. Immunol. 10:1110-1117. http://dx.doi.org/10.1038/ni.1785
-
(2009)
Nat. Immunol
, vol.10
, pp. 1110-1117
-
-
Mandal, M.1
Powers, S.E.2
Ochiai, K.3
Georgopoulos, K.4
Kee, B.L.5
Singh, H.6
Clark, M.R.7
-
36
-
-
0035170536
-
Activation of EGFP expression by Cre-mediated excision in a new ROSA26 reporter mouse strain
-
Mao, X., Y. Fujiwara, A. Chapdelaine, H. Yang, and S.H. Orkin. 2001. Activation of EGFP expression by Cre-mediated excision in a new ROSA26 reporter mouse strain. Blood. 97:324-326. http://dx.doi.org/10 .1182/blood.V97.1.324
-
(2001)
Blood
, vol.97
, pp. 324-326
-
-
Mao, X.1
Fujiwara, Y.2
Chapdelaine, A.3
Yang, H.4
Orkin, S.H.5
-
37
-
-
0036776370
-
Regulation of thymocyte differentiation: pre-TCR signals and beta-selection
-
Michie, A.M., and J.C. Zúñiga-Pflücker. 2002. Regulation of thymocyte differentiation: pre-TCR signals and beta-selection. Semin. Immunol. 14:311-323. http://dx.doi.org/10.1016/S1044-5323(02)00064-7
-
(2002)
Semin. Immunol
, vol.14
, pp. 311-323
-
-
Michie, A.M.1
Zúñiga-Pflücker, J.C.2
-
38
-
-
0033919659
-
Pre-B and pre-T-cell receptors: conservation of strategies in regulating early lymphocyte development
-
Muljo, S.A., and M.S. Schlissel. 2000. Pre-B and pre-T-cell receptors: conservation of strategies in regulating early lymphocyte development. Immunol. Rev. 175:80-93. http://dx.doi.org/10.1111/j.1600-065X.2000 .imr017509.x
-
(2000)
Immunol. Rev
, vol.175
, pp. 80-93
-
-
Muljo, S.A.1
Schlissel, M.S.2
-
39
-
-
4444240251
-
cAMP-induced degradation of cyclin D3 through association with GSK-3beta
-
Naderi, S., K.B. Gutzkow, H.U. Låhne, S. Lefdal, W.J. Ryves, A.J. Harwood, and H.K. Blomhoff. 2004. cAMP-induced degradation of cyclin D3 through association with GSK-3beta. J. Cell Sci. 117:3769-3783. http:// dx.doi.org/10.1242/jcs.01210
-
(2004)
J. Cell Sci
, vol.117
, pp. 3769-3783
-
-
Naderi, S.1
Gutzkow, K.B.2
Låhne, H.U.3
Lefdal, S.4
Ryves, W.J.5
Harwood, A.J.6
Blomhoff, H.K.7
-
40
-
-
27844560104
-
The pre-B-cell receptor induces silencing of VpreB and lambda5 transcription
-
Parker, M.J., S. Licence, L. Erlandsson, G.R. Galler, L. Chakalova, C.S. Osborne, G. Morgan, P. Fraser, H. Jumaa, T.H. Winkler, et al. 2005. The pre-B-cell receptor induces silencing of VpreB and lambda5 transcription. EMBO J. 24:3895-3905. http://dx.doi.org/10.1038/sj.emboj .7600850
-
(2005)
EMBO J
, vol.24
, pp. 3895-3905
-
-
Parker, M.J.1
Licence, S.2
Erlandsson, L.3
Galler, G.R.4
Chakalova, L.5
Osborne, C.S.6
Morgan, G.7
Fraser, P.8
Jumaa, H.9
Winkler, T.H.10
-
41
-
-
0035129248
-
NFATc1 and NFATc2 together control both T and B cell activation and differentiation
-
Peng, S.L., A.J. Gerth, A.M. Ranger, and L.H. Glimcher. 2001. NFATc1 and NFATc2 together control both T and B cell activation and differentiation. Immunity. 14:13-20. http://dx.doi.org/10.1016/S1074- 7613(01)00085-1
-
(2001)
Immunity
, vol.14
, pp. 13-20
-
-
Peng, S.L.1
Gerth, A.J.2
Ranger, A.M.3
Glimcher, L.H.4
-
42
-
-
84878611414
-
Inhibition of DYRK1A destabilizes EGFR and reduces EGFR-dependent glioblastoma growth
-
Pozo, N., C. Zahonero, P. Fernández, J.M. Liñares, A. Ayuso, M. Hagiwara, A. Pérez, J.R. Ricoy, A. Hernández-Laín, J.M. Sepúlveda, and P. Sánchez-Gómez. 2013. Inhibition of DYRK1A destabilizes EGFR and reduces EGFR-dependent glioblastoma growth. J. Clin. Invest. 123:2475- 2487. http://dx.doi.org/10.1172/JCI63623
-
(2013)
J. Clin. Invest
, vol.123
, pp. 2475- 2487
-
-
Pozo, N.1
Zahonero, C.2
Fernández, P.3
Liñares, J.M.4
Ayuso, A.5
Hagiwara, M.6
Pérez, A.7
Ricoy, J.R.8
Hernández-Laín, A.9
Sepúlveda, J.M.10
Sánchez-Gómez, P.11
-
43
-
-
84904497457
-
Dyrk1A induces pancreatic beta cell mass expansion and improves glucose tolerance
-
Rachdi L., D. Kariyawasam, V. Aiello, Y. Herault, N. Janel, J.M. Delabar, M. Polak, and R. Scharfmann. 2014. Dyrk1A induces pancreatic beta cell mass expansion and improves glucose tolerance. Cell Cycle. 13:2221-2229.
-
(2014)
Cell Cycle
, vol.13
, pp. 2221-2229
-
-
Rachdi, L.1
Kariyawasam, D.2
Aiello, V.3
Herault, Y.4
Janel, N.5
Delabar, J.M.6
Polak, M.7
Scharfmann, R.8
-
44
-
-
84896979169
-
Transcriptional control of early T and B cell developmental choices
-
Rothenberg, E.V. 2014. Transcriptional control of early T and B cell developmental choices. Annu. Rev. Immunol. 32:283-321. http://dx.doi .org/10.1146/annurev-immunol-032712-100024
-
(2014)
Annu. Rev. Immunol.
, vol.32
, pp. 283-321
-
-
Rothenberg, E.V.1
-
45
-
-
84867602759
-
Therapeutic targeting of the cyclin D3:CDK4/6 complex in T cell leukemia
-
Sawai, C.M., J. Freund, P. Oh, D. Ndiaye-Lobry, J.C. Bretz, A. Strikoudis, L. Genesca, T. Trimarchi, M.A. Kelliher, M. Clark, et al. 2012. Therapeutic targeting of the cyclin D3:CDK4/6 complex in T cell leukemia. Cancer Cell. 22:452-465. http://dx.doi.org/10.1016/j.ccr.2012.09.016
-
(2012)
Cancer Cell
, vol.22
, pp. 452-465
-
-
Sawai, C.M.1
Freund, J.2
Oh, P.3
Ndiaye-Lobry, D.4
Bretz, J.C.5
Strikoudis, A.6
Genesca, L.7
Trimarchi, T.8
Kelliher, M.A.9
Clark, M.10
-
46
-
-
69349101851
-
Nonprimed and DYRK1A-primed GSK3 beta-phosphorylation sites on MAP1B regulate microtubule dynamics in growing axons
-
Scales, T.M., S. Lin, M. Kraus, R.G. Goold, and P.R. Gordon-Weeks. 2009. Nonprimed and DYRK1A-primed GSK3 beta-phosphorylation sites on MAP1B regulate microtubule dynamics in growing axons. J. Cell Sci. 122:2424-2435. http://dx.doi.org/10.1242/jcs.040162
-
(2009)
J. Cell Sci
, vol.122
, pp. 2424-2435
-
-
Scales, T.M.1
Lin, S.2
Kraus, M.3
Goold, R.G.4
Gordon-Weeks, P.R.5
-
47
-
-
34548262714
-
Transcriptome analysis in primary B lymphoid precursors following induction of the pre-B cell receptor
-
Schuh, W., S. Meister, K. Herrmann, H. Bradl, and H.M. Jäck. 2008. Transcriptome analysis in primary B lymphoid precursors following induction of the pre-B cell receptor. Mol. Immunol. 45:362-375. http:// dx.doi.org/10.1016/j.molimm.2007.06.154
-
(2008)
Mol. Immunol
, vol.45
, pp. 362-375
-
-
Schuh, W.1
Meister, S.2
Herrmann, K.3
Bradl, H.4
Jäck, H.M.5
-
48
-
-
9144229104
-
Requirement for cyclin D3 in lymphocyte development and T cell leukemias
-
Sicinska, E., I. Aifantis, L. Le Cam, W. Swat, C. Borowski, Q. Yu, A.A. Ferrando, S.D. Levin, Y. Geng, H. von Boehmer, and P. Sicinski. 2003. Requirement for cyclin D3 in lymphocyte development and T cell leukemias. Cancer Cell. 4:451-461. http://dx.doi.org/10.1016/ S1535-6108(03)00301-5
-
(2003)
Cancer Cell
, vol.4
, pp. 451-461
-
-
Sicinska, E.1
Aifantis, I.2
Le Cam, L.3
Swat, W.4
Borowski, C.5
Yu, Q.6
Ferrando, A.A.7
Levin, S.D.8
Geng, Y.9
von Boehmer, H.10
Sicinski, P.11
-
49
-
-
84903760824
-
The Down syndrome-related protein kinase DYRK1A phosphorylates p27(Kip1) and Cyclin D1 and induces cell cycle exit and neuronal differentiation
-
Soppa, U., J. Schumacher, V. Florencio Ortiz, T. Pasqualon, F.J. Tejedor, and W. Becker. 2014. The Down syndrome-related protein kinase DYRK1A phosphorylates p27(Kip1) and Cyclin D1 and induces cell cycle exit and neuronal differentiation. Cell Cycle. 13:2084-2100. http:// dx.doi.org/10.4161/cc.29104
-
(2014)
Cell Cycle
, vol.13
, pp. 2084-2100
-
-
Soppa, U.1
Schumacher, J.2
Florencio Ortiz, V.3
Pasqualon, T.4
Tejedor, F.J.5
Becker, W.6
-
50
-
-
84878934964
-
Ubiquitin ligases and cell cycle control
-
Teixeira, L.K., and S.I. Reed. 2013. Ubiquitin ligases and cell cycle control. Annu. Rev. Biochem. 82:387-414. http://dx.doi.org/10.1146/annurevbiochem- 060410-105307
-
(2013)
Annu. Rev. Biochem
, vol.82
, pp. 387-414
-
-
Teixeira, L.K.1
Reed, S.I.2
-
51
-
-
33947153094
-
Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits
-
Thompson, E.C., B.S. Cobb, P. Sabbattini, S. Meixlsperger, V. Parelho, D. Liberg, B. Taylor, N. Dillon, K. Georgopoulos, H. Jumaa, et al. 2007. Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits. Immunity. 26:335-344. http://dx.doi.org/10.1016/j.immuni.2007.02.010
-
(2007)
Immunity
, vol.26
, pp. 335-344
-
-
Thompson, E.C.1
Cobb, B.S.2
Sabbattini, P.3
Meixlsperger, S.4
Parelho, V.5
Liberg, D.6
Taylor, B.7
Dillon, N.8
Georgopoulos, K.9
Jumaa, H.10
-
52
-
-
84859885816
-
Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks
-
Trapnell, C., A. Roberts, L. Goff, G. Pertea, D. Kim, D.R. Kelley, H. Pimentel, S.L. Salzberg, J.L. Rinn, and L. Pachter. 2012. Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks. Nat. Protoc. 7:562-578. http://dx.doi.org/10 .1038/nprot.2012.016
-
(2012)
Nat. Protoc
, vol.7
, pp. 562-578
-
-
Trapnell, C.1
Roberts, A.2
Goff, L.3
Pertea, G.4
Kim, D.5
Kelley, D.R.6
Pimentel, H.7
Salzberg, S.L.8
Rinn, J.L.9
Pachter, L.10
-
53
-
-
78651061790
-
The role of DYRK1A in neurodegenerative diseases
-
Wegiel, J., C.X. Gong, and Y.W. Hwang. 2011. The role of DYRK1A in neurodegenerative diseases. FEBS J. 278:236-245. http://dx.doi.org/ 10.1111/j.1742-4658.2010.07955.x
-
(2011)
FEBS J
, vol.278
, pp. 236-245
-
-
Wegiel, J.1
Gong, C.X.2
Hwang, Y.W.3
-
54
-
-
0035936113
-
The E2F1-3 transcription factors are essential for cellular proliferation
-
Wu, L., C. Timmers, B. Maiti, H.I. Saavedra, L. Sang, G.T. Chong, F. Nuckolls, P. Giangrande, F.A. Wright, S.J. Field, et al. 2001. The E2F1-3 transcription factors are essential for cellular proliferation. Nature. 414:457-462. http://dx.doi.org/10.1038/35106593
-
(2001)
Nature
, vol.414
, pp. 457-462
-
-
Wu, L.1
Timmers, C.2
Maiti, B.3
Saavedra, H.I.4
Sang, L.5
Chong, G.T.6
Nuckolls, F.7
Giangrande, P.8
Wright, F.A.9
Field, S.J.10
-
55
-
-
84867559699
-
Activity-dependent phosphorylation of dynamin 1 at serine 857
-
Xie, W., T. Adayev, H. Zhu, J. Wegiel, A. Wieraszko, and Y.W. Hwang. 2012. Activity-dependent phosphorylation of dynamin 1 at serine 857. Biochemistry. 51:6786-6796. http://dx.doi.org/10.1021/bi2017798
-
(2012)
Biochemistry
, vol.51
, pp. 6786-6796
-
-
Xie, W.1
Adayev, T.2
Zhu, H.3
Wegiel, J.4
Wieraszko, A.5
Hwang, Y.W.6
-
56
-
-
77949678789
-
Dyrk1A overexpression inhibits proliferation and induces premature neuronal differentiation of neural progenitor cells
-
Yabut, O., J. Domogauer, and G. D'Arcangelo. 2010. Dyrk1A overexpression inhibits proliferation and induces premature neuronal differentiation of neural progenitor cells. J. Neurosci. 30:4004-4014. http://dx.doi.org/ 10.1523/JNEUROSCI.4711-09.2010
-
(2010)
J. Neurosci
, vol.30
, pp. 4004-4014
-
-
Yabut, O.1
Domogauer, J.2
D'Arcangelo, G.3
-
57
-
-
9644279589
-
Recognition of phosphodegron motifs in human cyclin E by the SCF(Fbw7) ubiquitin ligase
-
Ye, X., G. Nalepa, M. Welcker, B.M. Kessler, E. Spooner, J. Qin, S.J. Elledge, B.E. Clurman, and J.W. Harper. 2004. Recognition of phosphodegron motifs in human cyclin E by the SCF(Fbw7) ubiquitin ligase. J. Biol. Chem. 279:50110-50119. http://dx.doi.org/10.1074/jbc .M409226200
-
(2004)
J. Biol. Chem
, vol.279
, pp. 50110-50119
-
-
Ye, X.1
Nalepa, G.2
Welcker, M.3
Kessler, B.M.4
Spooner, E.5
Qin, J.6
Elledge, S.J.7
Clurman, B.E.8
Harper, J.W.9
|