메뉴 건너뛰기




Volumn 22, Issue 4, 2012, Pages 452-465

Therapeutic Targeting of the Cyclin D3:CDK4/6 Complex in T Cell Leukemia

Author keywords

[No Author keywords available]

Indexed keywords

6 ACETYL 8 CYCLOPENTYL 5 METHYL 2 [5 (1 PIPERAZINYL) 2 PYRIDINYLAMINO] 8H PYRIDO[2,3 D]PYRIMIDIN 7 ONE; ANTINEOPLASTIC AGENT; CYCLIN D2; CYCLIN D3; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; PROTEIN P27;

EID: 84867602759     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccr.2012.09.016     Document Type: Article
Times cited : (153)

References (48)
  • 1
    • 42649124306 scopus 로고    scopus 로고
    • Molecular pathogenesis of T-cell leukaemia and lymphoma
    • Aifantis I., Raetz E., Buonamici S. Molecular pathogenesis of T-cell leukaemia and lymphoma. Nat. Rev. Immunol. 2008, 8:380-390.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 380-390
    • Aifantis, I.1    Raetz, E.2    Buonamici, S.3
  • 2
    • 19644386407 scopus 로고    scopus 로고
    • Multiple functions of D-type cyclins can antagonize pRb-mediated suppression of proliferation
    • Baker G.L., Landis M.W., Hinds P.W. Multiple functions of D-type cyclins can antagonize pRb-mediated suppression of proliferation. Cell Cycle 2005, 4:330-338.
    • (2005) Cell Cycle , vol.4 , pp. 330-338
    • Baker, G.L.1    Landis, M.W.2    Hinds, P.W.3
  • 3
    • 33747872306 scopus 로고    scopus 로고
    • A novel orally active small molecule potently induces G1 arrest in primary myeloma cells and prevents tumor growth by specific inhibition of cyclin-dependent kinase 4/6
    • Baughn L.B., Di Liberto M., Wu K., Toogood P.L., Louie T., Gottschalk R., Niesvizky R., Cho H., Ely S., Moore M.A., Chen-Kiang S. A novel orally active small molecule potently induces G1 arrest in primary myeloma cells and prevents tumor growth by specific inhibition of cyclin-dependent kinase 4/6. Cancer Res. 2006, 66:7661-7667.
    • (2006) Cancer Res. , vol.66 , pp. 7661-7667
    • Baughn, L.B.1    Di Liberto, M.2    Wu, K.3    Toogood, P.L.4    Louie, T.5    Gottschalk, R.6    Niesvizky, R.7    Cho, H.8    Ely, S.9    Moore, M.A.10    Chen-Kiang, S.11
  • 4
    • 22044440425 scopus 로고    scopus 로고
    • Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma
    • Bergsagel P.L., Kuehl W.M., Zhan F., Sawyer J., Barlogie B., Shaughnessy J. Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma. Blood 2005, 106:296-303.
    • (2005) Blood , vol.106 , pp. 296-303
    • Bergsagel, P.L.1    Kuehl, W.M.2    Zhan, F.3    Sawyer, J.4    Barlogie, B.5    Shaughnessy, J.6
  • 11
    • 77954757207 scopus 로고    scopus 로고
    • Therapeutic CDK4/6 inhibition in breast cancer: key mechanisms of response and failure
    • Dean J.L., Thangavel C., McClendon A.K., Reed C.A., Knudsen E.S. Therapeutic CDK4/6 inhibition in breast cancer: key mechanisms of response and failure. Oncogene 2010, 29:4018-4032.
    • (2010) Oncogene , vol.29 , pp. 4018-4032
    • Dean, J.L.1    Thangavel, C.2    McClendon, A.K.3    Reed, C.A.4    Knudsen, E.S.5
  • 13
    • 15844384256 scopus 로고    scopus 로고
    • A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice
    • Fero M.L., Rivkin M., Tasch M., Porter P., Carow C.E., Firpo E., Polyak K., Tsai L.H., Broudy V., Perlmutter R.M., et al. A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice. Cell 1996, 85:733-744.
    • (1996) Cell , vol.85 , pp. 733-744
    • Fero, M.L.1    Rivkin, M.2    Tasch, M.3    Porter, P.4    Carow, C.E.5    Firpo, E.6    Polyak, K.7    Tsai, L.H.8    Broudy, V.9    Perlmutter, R.M.10
  • 17
    • 0027938209 scopus 로고
    • Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age
    • Hunter T., Pines J. Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age. Cell 1994, 79:573-582.
    • (1994) Cell , vol.79 , pp. 573-582
    • Hunter, T.1    Pines, J.2
  • 20
    • 58149308526 scopus 로고    scopus 로고
    • Oncogenesis of T-ALL and nonmalignant consequences of overexpressing intracellular NOTCH1
    • Li X., Gounari F., Protopopov A., Khazaie K., von Boehmer H. Oncogenesis of T-ALL and nonmalignant consequences of overexpressing intracellular NOTCH1. J. Exp. Med. 2008, 205:2851-2861.
    • (2008) J. Exp. Med. , vol.205 , pp. 2851-2861
    • Li, X.1    Gounari, F.2    Protopopov, A.3    Khazaie, K.4    von Boehmer, H.5
  • 22
    • 33748184149 scopus 로고    scopus 로고
    • Mantle cell lymphoma cells express predominantly cyclin D1a isoform and are highly sensitive to selective inhibition of CDK4 kinase activity
    • Marzec M., Kasprzycka M., Lai R., Gladden A.B., Wlodarski P., Tomczak E., Nowell P., Deprimo S.E., Sadis S., Eck S., et al. Mantle cell lymphoma cells express predominantly cyclin D1a isoform and are highly sensitive to selective inhibition of CDK4 kinase activity. Blood 2006, 108:1744-1750.
    • (2006) Blood , vol.108 , pp. 1744-1750
    • Marzec, M.1    Kasprzycka, M.2    Lai, R.3    Gladden, A.B.4    Wlodarski, P.5    Tomczak, E.6    Nowell, P.7    Deprimo, S.E.8    Sadis, S.9    Eck, S.10
  • 26
    • 0030010591 scopus 로고    scopus 로고
    • Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
    • Nakayama K., Ishida N., Shirane M., Inomata A., Inoue T., Shishido N., Horii I., Loh D.Y., Nakayama K. Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 1996, 85:707-720.
    • (1996) Cell , vol.85 , pp. 707-720
    • Nakayama, K.1    Ishida, N.2    Shirane, M.3    Inomata, A.4    Inoue, T.5    Shishido, N.6    Horii, I.7    Loh, D.Y.8    Nakayama, K.9
  • 30
    • 0032937751 scopus 로고    scopus 로고
    • Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia
    • Rane S.G., Dubus P., Mettus R.V., Galbreath E.J., Boden G., Reddy E.P., Barbacid M. Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia. Nat. Genet. 1999, 22:44-52.
    • (1999) Nat. Genet. , vol.22 , pp. 44-52
    • Rane, S.G.1    Dubus, P.2    Mettus, R.V.3    Galbreath, E.J.4    Boden, G.5    Reddy, E.P.6    Barbacid, M.7
  • 32
    • 0031452914 scopus 로고    scopus 로고
    • Differential phosphorylation of T-47D human breast cancer cell substrates by D1-, D3-, E-, and A-type cyclin-CDK complexes
    • Sarcevic B., Lilischkis R., Sutherland R.L. Differential phosphorylation of T-47D human breast cancer cell substrates by D1-, D3-, E-, and A-type cyclin-CDK complexes. J. Biol. Chem. 1997, 272:33327-33337.
    • (1997) J. Biol. Chem. , vol.272 , pp. 33327-33337
    • Sarcevic, B.1    Lilischkis, R.2    Sutherland, R.L.3
  • 35
    • 8644219655 scopus 로고    scopus 로고
    • Living with or without cyclins and cyclin-dependent kinases
    • Sherr C.J., Roberts J.M. Living with or without cyclins and cyclin-dependent kinases. Genes Dev. 2004, 18:2699-2711.
    • (2004) Genes Dev. , vol.18 , pp. 2699-2711
    • Sherr, C.J.1    Roberts, J.M.2
  • 42
    • 57349194531 scopus 로고    scopus 로고
    • Differential regulation of cyclin D1 and D2 in protecting against cardiomyocyte proliferation
    • Tamamori-Adachi M., Goto I., Yamada K., Kitajima S. Differential regulation of cyclin D1 and D2 in protecting against cardiomyocyte proliferation. Cell Cycle 2008, 7:3768-3774.
    • (2008) Cell Cycle , vol.7 , pp. 3768-3774
    • Tamamori-Adachi, M.1    Goto, I.2    Yamada, K.3    Kitajima, S.4
  • 45
    • 13944282126 scopus 로고    scopus 로고
    • Negative cell-cycle regulators cooperatively control self-renewal and differentiation of haematopoietic stem cells
    • Walkley C.R., Fero M.L., Chien W.M., Purton L.E., McArthur G.A. Negative cell-cycle regulators cooperatively control self-renewal and differentiation of haematopoietic stem cells. Nat. Cell Biol. 2005, 7:172-178.
    • (2005) Nat. Cell Biol. , vol.7 , pp. 172-178
    • Walkley, C.R.1    Fero, M.L.2    Chien, W.M.3    Purton, L.E.4    McArthur, G.A.5
  • 46
    • 34250363611 scopus 로고    scopus 로고
    • Rb regulates interactions between hematopoietic stem cells and their bone marrow microenvironment
    • Walkley C.R., Shea J.M., Sims N.A., Purton L.E., Orkin S.H. Rb regulates interactions between hematopoietic stem cells and their bone marrow microenvironment. Cell 2007, 129:1081-1095.
    • (2007) Cell , vol.129 , pp. 1081-1095
    • Walkley, C.R.1    Shea, J.M.2    Sims, N.A.3    Purton, L.E.4    Orkin, S.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.