Dyrk1A induces pancreatic β cell mass expansion and improves glucose tolerance

Cell Cycle

Volumn 13, Issue 14, 2014, Pages 2221-2229

  Rachdi, Latif ^a   Kariawasam, Dulanjalee ^a,b   Aiëllo, Virginie ^a   Herault, Yann ^c   Janel, Nathalie ^d   Delabar, Jean Maurice ^d   Polak, Michel ^a,b   Scharfmann, Raphaël ^a  

^a INSTITUT COCHIN   (France)

^b HÔPITAL NECKER ENFANTS MALADES   (France)

^c INSTITUT CLINIQUE DE LA SOURIS   (France)

^d Groupe Hospitalier Pitié Salpêtrière   (France)

Author keywords

Beta cell; Diabetes; DYRK1A; Growth; Proliferation

Indexed keywords

DUAL SPECIFICITY PHOSPHATASE; DYRK1A PROTEIN; GLUCOSE; INSULIN; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; DYRK KINASE; GLUCOSE BLOOD LEVEL; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL EXPANSION; CELL PROLIFERATION; CELL SIZE; CELL SIZING (MEASUREMENT); CONTROLLED STUDY; GENE OVEREXPRESSION; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE; GLUCOSE TOLERANCE TEST; HYPERINSULINEMIA; IMMUNOFLUORESCENCE; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID DIET; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; UPREGULATION; ANIMAL; BIOSYNTHESIS; BLOOD; C57BL MOUSE; DIABETES MELLITUS, EXPERIMENTAL; ENZYMOLOGY; GENETICS; GENOTYPE; HYPERINSULINISM; METABOLISM; PATHOLOGY; PHENOTYPE; SIGNAL TRANSDUCTION; TIME; TRANSGENIC MOUSE;

ANIMALS; BIOMARKERS; BLOOD GLUCOSE; CELL PROLIFERATION; CELL SIZE; DIABETES MELLITUS, EXPERIMENTAL; DIET, HIGH-FAT; GENOTYPE; HYPERINSULINISM; INSULIN; INSULIN-SECRETING CELLS; MALE; MICE, INBRED C57BL; MICE, TRANSGENIC; PHENOTYPE; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; TIME FACTORS; UP-REGULATION;

EID: 84904497457     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.29250     Document Type: Article

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