Transient expression of Mnb/dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling

Development

Volumn 138, Issue 12, 2011, Pages 2543-2554

  Hämmerle, Barbara ^a   Ulin, Edgar ^a   Guimera, Jordi ^b   Becker, Walter ^c   Guillemot, François ^d   Tejedor, Francisco J ^a  

^a MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

^b HMGU Institute of Developmental Genetics   (Germany)

^c RWTH AACHEN UNIVERSITY   (Germany)

^d NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

Chick; Down's syndrome; Mouse; Neural proliferation; Neurogenesis; Neuronal differentiation

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1B; MINIBRAIN DUAL SPECIFICITY TYROSINE Y REGULATED KINASE 1 A; NOTCH RECEPTOR; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL CYCLE; CELL DIFFERENTIATION; EMBRYO; ENZYME ACTIVITY; GENE EXPRESSION; MOUSE; NEURAL STEM CELL; NEUROEPITHELIUM; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CELL CYCLE; CELL DIFFERENTIATION; CHICKENS; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; NEURAL STEM CELLS; PC12 CELLS; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; RATS; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION;

VERTEBRATA;

EID: 79957648087     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.066167     Document Type: Article

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