Triplication of dyrk1a causes retinal structural and functional alterations in down syndrome

Human Molecular Genetics

Volumn 22, Issue 14, 2013, Pages 2275-2284

  Laguna, Ariadna ^a,b,g   Barallobre, María José ^a   Marchena, Miguel Ángel ^c   Mateus, Catarina ^d   Ramírez, Erika ^b   Martínez Cue, Carmen ^e   Delabar, Jean M ^f   Castelo Branco, Miguel ^d   de la Villa, Pedro ^c   Arbonés, Maria L ^a  

^a CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES RARAS CIBERER   (Spain)

^b CENTRE FOR GENOMIC REGULATION CRG   (Spain)

^c UNIVERSITY OF ALCALÁ   (Spain)

^d UNIVERSITY OF COIMBRA   (Portugal)

^e UNIVERSITY OF CANTABRIA   (Spain)

^f Groupe Hospitalier Pitié Salpêtrière   (France)

^g KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

DUAL SPECIFICITY TYROSINE PHOSPHORYLATION REGULATED KINASE 1A; PROTEIN KINASE; UNCLASSIFIED DRUG; CASPASE 9; DYRK KINASE; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CENTRAL NERVOUS SYSTEM; CHROMOSOME 21; COGNITIVE DEVELOPMENT; CONTROLLED STUDY; CORRELATIONAL STUDY; DAILY LIFE ACTIVITY; DOWN SYNDROME; FEMALE; GENE DOSAGE; GENE OVEREXPRESSION; IN VIVO STUDY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RESCUE PERSONNEL; RETINA NEUROEPITHELIAL LAYER; TRISOMY 21; VISION; ADULT; ANATOMY AND HISTOLOGY; ANIMAL; C57BL MOUSE; CYTOLOGY; DISEASE MODEL; ENZYMOLOGY; GENE AMPLIFICATION; GENETICS; HUMAN; MALE; METABOLISM; PATHOPHYSIOLOGY; RETINA; YOUNG ADULT;

MUS;

ADULT; ANIMALS; APOPTOSIS; CASPASE 9; DISEASE MODELS, ANIMAL; DOWN SYNDROME; FEMALE; GENE AMPLIFICATION; GENE DOSAGE; HUMANS; MALE; MICE; MICE, INBRED C57BL; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; RETINA; YOUNG ADULT;

EID: 84896559398     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddt125     Document Type: Article

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