-
1
-
-
84878864199
-
The hallmarks of aging
-
[1] López-Otín, C., Blasco, M.A., Partridge, L., et al. The hallmarks of aging. Cell 153 (2013), 1194–1217.
-
(2013)
Cell
, vol.153
, pp. 1194-1217
-
-
López-Otín, C.1
Blasco, M.A.2
Partridge, L.3
-
2
-
-
50549218525
-
The limited in vitro lifetime of human diploid cell strains
-
[2] Hayflick, L., The limited in vitro lifetime of human diploid cell strains. Exp Cell Res 37 (1965), 614–636.
-
(1965)
Exp Cell Res
, vol.37
, pp. 614-636
-
-
Hayflick, L.1
-
3
-
-
34548186667
-
Cellular senescence: when bad things happen to good cells
-
[3] Campisi, J., d׳Adda di Fagagna, F., Cellular senescence: when bad things happen to good cells. Nat Rev Mol Cell Biol 8 (2007), 729–740.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 729-740
-
-
Campisi, J.1
d׳Adda di Fagagna, F.2
-
4
-
-
80855128461
-
Cellular senescence: a link between cancer and age-related degenerative disease?
-
[4] Campisi, J., Andersen, J.K., Kapahi, P., et al. Cellular senescence: a link between cancer and age-related degenerative disease?. Semin Cancer Biol 21 (2011), 354–359.
-
(2011)
Semin Cancer Biol
, vol.21
, pp. 354-359
-
-
Campisi, J.1
Andersen, J.K.2
Kapahi, P.3
-
5
-
-
66149167336
-
DNA damage response and cellular senescence in tissues of aging mice
-
[5] Wang, C., Jurk, D., Maddick, M., et al. DNA damage response and cellular senescence in tissues of aging mice. Aging Cell 8 (2009), 311–323.
-
(2009)
Aging Cell
, vol.8
, pp. 311-323
-
-
Wang, C.1
Jurk, D.2
Maddick, M.3
-
6
-
-
2542609402
-
Lung fibroblasts from patients with emphysema show a reduced proliferation rate in culture
-
[6] Holz, O., Zühlke, I., Jaksztat, E., et al. Lung fibroblasts from patients with emphysema show a reduced proliferation rate in culture. Eur Respir J 24 (2004), 575–579.
-
(2004)
Eur Respir J
, vol.24
, pp. 575-579
-
-
Holz, O.1
Zühlke, I.2
Jaksztat, E.3
-
7
-
-
84904702784
-
Cellular senescence: from physiology to pathology
-
[7] Muñoz-Espín, D., Serrano, M., Cellular senescence: from physiology to pathology. Nat Rev Mol Cell Biol 15 (2014), 482–496.
-
(2014)
Nat Rev Mol Cell Biol
, vol.15
, pp. 482-496
-
-
Muñoz-Espín, D.1
Serrano, M.2
-
8
-
-
77949881221
-
The senescence-associated secretory phenotype: the dark side of tumor suppression
-
[8] Coppe, J.P., Desprez, P.Y., Krtolica, A., et al. The senescence-associated secretory phenotype: the dark side of tumor suppression. Annu Rev Pathol 5 (2010), 99–118.
-
(2010)
Annu Rev Pathol
, vol.5
, pp. 99-118
-
-
Coppe, J.P.1
Desprez, P.Y.2
Krtolica, A.3
-
9
-
-
64349123107
-
Autophagy mediates the mitotic senescence transition
-
[9] Young, A.R., Narita, M., Ferreira, M., et al. Autophagy mediates the mitotic senescence transition. Genes Dev 23 (2009), 798–803.
-
(2009)
Genes Dev
, vol.23
, pp. 798-803
-
-
Young, A.R.1
Narita, M.2
Ferreira, M.3
-
10
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
[10] Mizushima, N., Levine, B., Cuervo, A.M., et al. Autophagy fights disease through cellular self-digestion. Nature 451 (2008), 1069–1075.
-
(2008)
Nature
, vol.451
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
-
11
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
[11] Levine, B., Kroemer, G., Autophagy in the pathogenesis of disease. Cell 132 (2008), 27–42.
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
12
-
-
72549095406
-
Regulation mechanisms and signaling pathways of autophagy
-
[12] He, C., Klionsky, D.J., Regulation mechanisms and signaling pathways of autophagy. Annu Rev Genet 43 (2009), 67–93.
-
(2009)
Annu Rev Genet
, vol.43
, pp. 67-93
-
-
He, C.1
Klionsky, D.J.2
-
13
-
-
81055144784
-
Autophagy: renovation of cells and tissues
-
[13] Mizushima, N., Komatsu, M., Autophagy: renovation of cells and tissues. Cell 147 (2011), 728–741.
-
(2011)
Cell
, vol.147
, pp. 728-741
-
-
Mizushima, N.1
Komatsu, M.2
-
14
-
-
79251577061
-
The regulation of autophagy—unanswered questions
-
[14] Chen, Y., Klionsky, D.J., The regulation of autophagy—unanswered questions. J Cell Sci 124 (2011), 161–170.
-
(2011)
J Cell Sci
, vol.124
, pp. 161-170
-
-
Chen, Y.1
Klionsky, D.J.2
-
15
-
-
66049133683
-
Aging: central role for autophagy and the lysosomal degradative system
-
[15] Rajawat, Y.S., Hilioti, Z., Bossis, I., Aging: central role for autophagy and the lysosomal degradative system. Ageing Res Rev 8 (2009), 199–213.
-
(2009)
Ageing Res Rev
, vol.8
, pp. 199-213
-
-
Rajawat, Y.S.1
Hilioti, Z.2
Bossis, I.3
-
16
-
-
84920421073
-
Essential role for autophagy in life span extension
-
[16] Madeo, F., Zimmermann, A., Maiuri, M.C., et al. Essential role for autophagy in life span extension. J Clin Invest 125 (2015), 85–93.
-
(2015)
J Clin Invest
, vol.125
, pp. 85-93
-
-
Madeo, F.1
Zimmermann, A.2
Maiuri, M.C.3
-
17
-
-
77956416339
-
Autophagy in mammalian development and differentiation
-
[17] Mizushima, N., Levine, B., Autophagy in mammalian development and differentiation. Nat Cell Biol 12 (2010), 823–830.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 823-830
-
-
Mizushima, N.1
Levine, B.2
-
18
-
-
84871749760
-
Mitochondrial morphology in mitophagy and macroautophagy
-
[18] Gomes, L.C., Scorrano, L., Mitochondrial morphology in mitophagy and macroautophagy. Biochim Biophys Acta 1833 (2013), 205–212.
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 205-212
-
-
Gomes, L.C.1
Scorrano, L.2
-
19
-
-
77953149043
-
Calorie restriction: decelerating mTOR-driven aging from cells to organisms (including humans)
-
[19] Blagosklonny, M.V., Calorie restriction: decelerating mTOR-driven aging from cells to organisms (including humans). Cell Cycle 9 (2010), 683–688.
-
(2010)
Cell Cycle
, vol.9
, pp. 683-688
-
-
Blagosklonny, M.V.1
-
20
-
-
75149128169
-
The life span-prolonging effect of sirtuin-1 is mediated by autophagy
-
[20] Morselli, E., Maiuri, M.C., Markaki, M., et al. The life span-prolonging effect of sirtuin-1 is mediated by autophagy. Autophagy 6 (2010), 186–188.
-
(2010)
Autophagy
, vol.6
, pp. 186-188
-
-
Morselli, E.1
Maiuri, M.C.2
Markaki, M.3
-
21
-
-
79251587803
-
Phosphorylation of ulk1 (hatg1) by amp-activated protein kinase connects energy sensing to mitophagy
-
[21] Egan, D.F., Shackelford, D.B., Mihaylova, M.M., et al. Phosphorylation of ulk1 (hatg1) by amp-activated protein kinase connects energy sensing to mitophagy. Science 331 (2011), 456–461.
-
(2011)
Science
, vol.331
, pp. 456-461
-
-
Egan, D.F.1
Shackelford, D.B.2
Mihaylova, M.M.3
-
22
-
-
41549138483
-
A role for the nad-dependent deacetylase sirt1 in the regulation of autophagy
-
[22] Lee, I.H., Cao, L., Mostoslavsky, R., et al. A role for the nad-dependent deacetylase sirt1 in the regulation of autophagy. Proc Natl Acad Sci USA 105 (2008), 3374–3379.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 3374-3379
-
-
Lee, I.H.1
Cao, L.2
Mostoslavsky, R.3
-
23
-
-
77951157657
-
Calorie restriction enhances cell adaptation to hypoxia through sirt1-dependent mitochondrial autophagy in mouse aged kidney
-
[23] Kume, S., Uzu, T., Horiike, K., et al. Calorie restriction enhances cell adaptation to hypoxia through sirt1-dependent mitochondrial autophagy in mouse aged kidney. J Clin Invest 120 (2010), 1043–1055.
-
(2010)
J Clin Invest
, vol.120
, pp. 1043-1055
-
-
Kume, S.1
Uzu, T.2
Horiike, K.3
-
24
-
-
84861831957
-
Sirt1 protects against emphysema via foxo3-mediated reduction of premature senescence in mice
-
[24] Yao, H., Chung, S., Hwang, J.W., et al. Sirt1 protects against emphysema via foxo3-mediated reduction of premature senescence in mice. J Clin Invest 122 (2012), 2032–2045.
-
(2012)
J Clin Invest
, vol.122
, pp. 2032-2045
-
-
Yao, H.1
Chung, S.2
Hwang, J.W.3
-
25
-
-
84655163784
-
Emerging roles of molecular chaperones and co-chaperones in selective autophagy: focus on BAG proteins
-
[25] Gamerdinger, M., Carra, S., Behl, C., Emerging roles of molecular chaperones and co-chaperones in selective autophagy: focus on BAG proteins. Mol Med 89:12 (2011), 1175–1182.
-
(2011)
Mol Med
, vol.89
, Issue.12
, pp. 1175-1182
-
-
Gamerdinger, M.1
Carra, S.2
Behl, C.3
-
26
-
-
41549086994
-
Lipid mediators of autophagy in stress-induced premature senescence of endothelial cells
-
[26] Patschan, S., Chen, J., Polotskaia, A., et al. Lipid mediators of autophagy in stress-induced premature senescence of endothelial cells. Am J Physiol Heart Circ Physiol 294 (2008), H1119–H1129.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.294
, pp. H1119-H1129
-
-
Patschan, S.1
Chen, J.2
Polotskaia, A.3
-
27
-
-
84871868506
-
Autophagy, senescence, and apoptosis
-
[27] Goehe, R.W., Bristol, M.L., Wilson, E.N., et al. Autophagy, senescence, and apoptosis. Methods Mol Biol 962 (2013), 31–48.
-
(2013)
Methods Mol Biol
, vol.962
, pp. 31-48
-
-
Goehe, R.W.1
Bristol, M.L.2
Wilson, E.N.3
-
28
-
-
73149091434
-
Senescence hypothesis for the pathogenetic mechanism of chronic obstructive pulmonary disease
-
[28] Aoshiba, K., Nagai, A., Senescence hypothesis for the pathogenetic mechanism of chronic obstructive pulmonary disease. Proc Am Thorac Soc 6 (2009), 596–601.
-
(2009)
Proc Am Thorac Soc
, vol.6
, pp. 596-601
-
-
Aoshiba, K.1
Nagai, A.2
-
29
-
-
33749841717
-
Alveolar cell senescence in patients with pulmonary emphysema
-
[29] Tsuji, T., Aoshiba, K., Nagai, A., Alveolar cell senescence in patients with pulmonary emphysema. Am J Respir Crit Care Med 174 (2006), 886–893.
-
(2006)
Am J Respir Crit Care Med
, vol.174
, pp. 886-893
-
-
Tsuji, T.1
Aoshiba, K.2
Nagai, A.3
-
30
-
-
84857710635
-
Involvement of creatine kinase b in cigarette smoke-induced bronchial epithelial cell senescence
-
[30] Hara, H., Araya, J., Takasaka, N., et al. Involvement of creatine kinase b in cigarette smoke-induced bronchial epithelial cell senescence. Am J Respir Cell Mol Biol 46 (2012), 306–312.
-
(2012)
Am J Respir Cell Mol Biol
, vol.46
, pp. 306-312
-
-
Hara, H.1
Araya, J.2
Takasaka, N.3
-
31
-
-
33645781050
-
Lung fibroblasts from patients with emphysema show markers of senescence in vitro
-
[31] Müller, K.C., Welker, L., Paasch, K., et al. Lung fibroblasts from patients with emphysema show markers of senescence in vitro. Respir Res, 7, 2006, 32.
-
(2006)
Respir Res
, vol.7
, pp. 32
-
-
Müller, K.C.1
Welker, L.2
Paasch, K.3
-
32
-
-
84929466240
-
Accelerated ageing of the lung in COPD: new concepts
-
[32] Mercado, N., Ito, K., Barnes, P.J., Accelerated ageing of the lung in COPD: new concepts. Thorax 70 (2015), 482–489.
-
(2015)
Thorax
, vol.70
, pp. 482-489
-
-
Mercado, N.1
Ito, K.2
Barnes, P.J.3
-
33
-
-
13944253348
-
Calorie restriction—the SIR2 connection
-
[33] Guarente, L., Picard, F., Calorie restriction—the SIR2 connection. Cell 120 (2005), 473–482.
-
(2005)
Cell
, vol.120
, pp. 473-482
-
-
Guarente, L.1
Picard, F.2
-
34
-
-
42649146208
-
SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease
-
[34] Rajendrasozhan, S., Yang, S.R., Kinnula, V.L., et al. SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 177 (2008), 861–870.
-
(2008)
Am J Respir Crit Care Med
, vol.177
, pp. 861-870
-
-
Rajendrasozhan, S.1
Yang, S.R.2
Kinnula, V.L.3
-
35
-
-
84860880317
-
SIRT1 as a therapeutic target in inflammaging of the pulmonary disease
-
[35] Rahman, I., Kinnula, V.L., Gorbunova, V., et al. SIRT1 as a therapeutic target in inflammaging of the pulmonary disease. Prev Med 54 (2012), S20–S28.
-
(2012)
Prev Med
, vol.54
, pp. S20-S28
-
-
Rahman, I.1
Kinnula, V.L.2
Gorbunova, V.3
-
36
-
-
84900538900
-
SIRT1 protects against cigarette smoke-induced lung oxidative stress via a FOXO3-dependent mechanism
-
[36] Yao, H., Sundar, I.K., Ahmad, T., et al. SIRT1 protects against cigarette smoke-induced lung oxidative stress via a FOXO3-dependent mechanism. Am J Physiol Lung Cell Mol Physiol 306 (2014), L816–L828.
-
(2014)
Am J Physiol Lung Cell Mol Physiol
, vol.306
, pp. L816-L828
-
-
Yao, H.1
Sundar, I.K.2
Ahmad, T.3
-
37
-
-
84996435783
-
Long-term IGF-1 exposure decreases autophagy and cell viability
-
[37] Kanfi, Y., Naiman, S., Amir, G., et al. Long-term IGF-1 exposure decreases autophagy and cell viability. PLoS One, 5, 2010, e12592.
-
(2010)
PLoS One
, vol.5
, pp. e12592
-
-
Kanfi, Y.1
Naiman, S.2
Amir, G.3
-
38
-
-
84893401717
-
Autophagy induction by SIRT6 through attenuation of insulin-like growth factor signaling is involved in the regulation of human bronchial epithelial cell senescence
-
[38] Takasaka, N., Araya, J., Hara, H., et al. Autophagy induction by SIRT6 through attenuation of insulin-like growth factor signaling is involved in the regulation of human bronchial epithelial cell senescence. J Immunol 192 (2014), 958–968.
-
(2014)
J Immunol
, vol.192
, pp. 958-968
-
-
Takasaka, N.1
Araya, J.2
Hara, H.3
-
39
-
-
84871916713
-
Insufficient autophagy promotes bronchial epithelial cell senescence in chronic obstructive pulmonary disease
-
[39] Fujii, S., Hara, H., Araya, J., et al. Insufficient autophagy promotes bronchial epithelial cell senescence in chronic obstructive pulmonary disease. Oncoimmunology 1 (2012), 630–641.
-
(2012)
Oncoimmunology
, vol.1
, pp. 630-641
-
-
Fujii, S.1
Hara, H.2
Araya, J.3
-
40
-
-
53749087325
-
Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease
-
[40] Chen, Z.H., Kim, H.P., Sciurba, F.C., et al. Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease. PLoS One, 3, 2008, e3316.
-
(2008)
PLoS One
, vol.3
, pp. e3316
-
-
Chen, Z.H.1
Kim, H.P.2
Sciurba, F.C.3
-
41
-
-
78650434097
-
Autophagy protein microtubule-associated protein 1 light chain-3b (lc3b) activates extrinsic apoptosis during cigarette smoke-induced emphysema
-
[41] Chen, Z.H., Lam, H.C., Jin, Y., et al. Autophagy protein microtubule-associated protein 1 light chain-3b (lc3b) activates extrinsic apoptosis during cigarette smoke-induced emphysema. Proc Natl Acad Sci USA 107 (2010), 18880–18885.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 18880-18885
-
-
Chen, Z.H.1
Lam, H.C.2
Jin, Y.3
-
42
-
-
79959354999
-
Mitochondria and the autophagy-inflammation-cell death axis in organismal aging
-
[42] Green, D.R., Galluzzi, L., Kroemer, G., Mitochondria and the autophagy-inflammation-cell death axis in organismal aging. Science 333 (2011), 1109–1112.
-
(2011)
Science
, vol.333
, pp. 1109-1112
-
-
Green, D.R.1
Galluzzi, L.2
Kroemer, G.3
-
43
-
-
84859429500
-
Mitochondria and autophagy: critical interplay between the two homeostats
-
[43] Okamoto, K., Kondo-Okamoto, N., Mitochondria and autophagy: critical interplay between the two homeostats. Biochim Biophys Acta 1820 (2012), 595–600.
-
(2012)
Biochim Biophys Acta
, vol.1820
, pp. 595-600
-
-
Okamoto, K.1
Kondo-Okamoto, N.2
-
44
-
-
84887581901
-
Mitochondrial fragmentation in cigarette smoke induced-bronchial epithelial cell senescence
-
[44] Hara, H., Araya, J., Ito, S., et al. Mitochondrial fragmentation in cigarette smoke induced-bronchial epithelial cell senescence. Am J Physiol Lung Cell Mol Physiol 305 (2013), L737–L746.
-
(2013)
Am J Physiol Lung Cell Mol Physiol
, vol.305
, pp. L737-L746
-
-
Hara, H.1
Araya, J.2
Ito, S.3
-
45
-
-
75949130828
-
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
-
[45] Geisler, S., Holmstrom, K.M., Skujat, D., et al. PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat Cell Biol 12 (2010), 119–131.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 119-131
-
-
Geisler, S.1
Holmstrom, K.M.2
Skujat, D.3
-
46
-
-
49649097747
-
Loss of pink1 causes mitochondrial functional defects and increased sensitivity to oxidative stress
-
[46] Gautier, C.A., Kitada, T., Shen, J., Loss of pink1 causes mitochondrial functional defects and increased sensitivity to oxidative stress. Proc Natl Acad Sci USA 105 (2008), 11364–11369.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 11364-11369
-
-
Gautier, C.A.1
Kitada, T.2
Shen, J.3
-
47
-
-
84943800210
-
PARK2-mediated mitophagy is involved in regulation of HBEC senescence in COPD pathogenesis
-
[47] Ito, S., Araya, J., Kurita, Y., et al. PARK2-mediated mitophagy is involved in regulation of HBEC senescence in COPD pathogenesis. Autophagy 11 (2015), 547–559.
-
(2015)
Autophagy
, vol.11
, pp. 547-559
-
-
Ito, S.1
Araya, J.2
Kurita, Y.3
-
48
-
-
84907010947
-
Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD
-
[48] Mizumura, K., Cloonan, S.M., Nakahira, K., et al. Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD. J Clin Invest 124 (2014), 3987–4003.
-
(2014)
J Clin Invest
, vol.124
, pp. 3987-4003
-
-
Mizumura, K.1
Cloonan, S.M.2
Nakahira, K.3
-
49
-
-
84859383698
-
Hyperoxia-induced lc3b interacts with the fas apoptotic pathway in epithelial cell death
-
[49] Tanaka, A., Jin, Y., Lee, S.J., et al. Hyperoxia-induced lc3b interacts with the fas apoptotic pathway in epithelial cell death. Am J Respir Cell Mol Biol 46 (2012), 507–514.
-
(2012)
Am J Respir Cell Mol Biol
, vol.46
, pp. 507-514
-
-
Tanaka, A.1
Jin, Y.2
Lee, S.J.3
-
50
-
-
78149476302
-
Identification of an autophagy defect in smokers׳ alveolar macrophages
-
[50] Monick, M.M., Powers, L.S., Walters, K., et al. Identification of an autophagy defect in smokers׳ alveolar macrophages. J Immunol 185 (2010), 5425–5435.
-
(2010)
J Immunol
, vol.185
, pp. 5425-5435
-
-
Monick, M.M.1
Powers, L.S.2
Walters, K.3
-
51
-
-
79952717349
-
ATS/ERS/JRS/ALAT Committee on Idiopathic Pulmonary Fibrosis. An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management
-
[51] Raghu, G., Collard, H.R., Egan, J.J., et al. ATS/ERS/JRS/ALAT Committee on Idiopathic Pulmonary Fibrosis. An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management. Am J Respir Crit Care Med 183 (2011), 788–824.
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 788-824
-
-
Raghu, G.1
Collard, H.R.2
Egan, J.J.3
-
52
-
-
34250614359
-
Adult-onset pulmonary fibrosis caused by mutations in telomerase
-
[52] Tsakiri, K.D., Cronkhite, J.T., Kuan, P.J., et al. Adult-onset pulmonary fibrosis caused by mutations in telomerase. Proc Natl Acad Sci USA 104 (2007), 7552–7557.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 7552-7557
-
-
Tsakiri, K.D.1
Cronkhite, J.T.2
Kuan, P.J.3
-
53
-
-
34047188508
-
Telomerase mutations in families with idiopathic pulmonary fibrosis
-
[53] Armanios, M.Y., Chen, J.J., Cogan, J.D., et al. Telomerase mutations in families with idiopathic pulmonary fibrosis. N Engl J Med 356 (2007), 1317–1326.
-
(2007)
N Engl J Med
, vol.356
, pp. 1317-1326
-
-
Armanios, M.Y.1
Chen, J.J.2
Cogan, J.D.3
-
54
-
-
51349113450
-
Short telomeres are a risk factor for idiopathic pulmonary fibrosis
-
[54] Alder, J.K., Chen, J.J., Lancaster, L., et al. Short telomeres are a risk factor for idiopathic pulmonary fibrosis. Proc Natl Acad Sci USA 105 (2008), 13051–13056.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13051-13056
-
-
Alder, J.K.1
Chen, J.J.2
Lancaster, L.3
-
55
-
-
52749083873
-
Telomere shortening in familial and sporadic pulmonary fibrosis
-
[55] Cronkhite, J.T., Xing, C., Raghu, G., et al. Telomere shortening in familial and sporadic pulmonary fibrosis. Am J Respir Crit Care Med 178 (2008), 729–737.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 729-737
-
-
Cronkhite, J.T.1
Xing, C.2
Raghu, G.3
-
56
-
-
84903995680
-
Effect of telomere length on survival in patients with idiopathic pulmonary fibrosis: an observational cohort study with independent validation
-
[56] Stuart, B.D., Lee, J.S., Kozlitina, J., et al. Effect of telomere length on survival in patients with idiopathic pulmonary fibrosis: an observational cohort study with independent validation. Lancet Respir Med 2 (2014), 557–565.
-
(2014)
Lancet Respir Med
, vol.2
, pp. 557-565
-
-
Stuart, B.D.1
Lee, J.S.2
Kozlitina, J.3
-
57
-
-
75949125865
-
Abnormal expression of telomerase/apoptosis limits type II alveolar epithelial cell replication in the early remodeling of usual interstitial pneumonia/idiopathic pulmonary fibrosis
-
[57] Waisberg, D.R., Barbas-Filho, J.V., Parra, E.R., et al. Abnormal expression of telomerase/apoptosis limits type II alveolar epithelial cell replication in the early remodeling of usual interstitial pneumonia/idiopathic pulmonary fibrosis. Hum Pathol 41 (2010), 385–391.
-
(2010)
Hum Pathol
, vol.41
, pp. 385-391
-
-
Waisberg, D.R.1
Barbas-Filho, J.V.2
Parra, E.R.3
-
58
-
-
84903124023
-
Chitinase 3-like 1 suppresses injury and promotes fibroproliferative responses in mammalian lung fibrosis
-
[58] Zhou, Y., Peng, H., Sun, H., et al. Chitinase 3-like 1 suppresses injury and promotes fibroproliferative responses in mammalian lung fibrosis. Sci Transl Med, 6, 2014, 240ra76.
-
(2014)
Sci Transl Med
, vol.6
, pp. 240ra76
-
-
Zhou, Y.1
Peng, H.2
Sun, H.3
-
59
-
-
36849062326
-
Telomerase activity is required for bleomycin-induced pulmonary fibrosis in mice
-
[59] Liu, T., Chung, M.J., Ullenbruch, M., et al. Telomerase activity is required for bleomycin-induced pulmonary fibrosis in mice. J Clin Invest 117 (2007), 3800–3809.
-
(2007)
J Clin Invest
, vol.117
, pp. 3800-3809
-
-
Liu, T.1
Chung, M.J.2
Ullenbruch, M.3
-
60
-
-
79955047394
-
Accelerated epithelial cell senescence in IPF and the inhibitory role of sirt6 in TGF-β-induced senescence of human bronchial epithelial cells
-
[60] Minagawa, S., Araya, J., Numata, T., et al. Accelerated epithelial cell senescence in IPF and the inhibitory role of sirt6 in TGF-β-induced senescence of human bronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol 300 (2011), L391–L401.
-
(2011)
Am J Physiol Lung Cell Mol Physiol
, vol.300
, pp. L391-L401
-
-
Minagawa, S.1
Araya, J.2
Numata, T.3
-
61
-
-
0037097680
-
TGF-β1 as an enhancer of Fas-mediated apoptosis of lung epithelial cells
-
[61] Hagimoto, N., Kuwano, K., Inoshima, I., et al. TGF-β1 as an enhancer of Fas-mediated apoptosis of lung epithelial cells. J Immunol 168 (2002), 6470–6478.
-
(2002)
J Immunol
, vol.168
, pp. 6470-6478
-
-
Hagimoto, N.1
Kuwano, K.2
Inoshima, I.3
-
62
-
-
84889565689
-
Senescence is a developmental mechanism that contributes to embryonic growth and patterning
-
[62] Storer, M., Mas, A., Robert-Moreno, A., et al. Senescence is a developmental mechanism that contributes to embryonic growth and patterning. Cell 155 (2013), 1119–1130.
-
(2013)
Cell
, vol.155
, pp. 1119-1130
-
-
Storer, M.1
Mas, A.2
Robert-Moreno, A.3
-
63
-
-
84864022325
-
Autophagy in idiopathic pulmonary fibrosis
-
[63] Patel, A.S., Lin, L., Geyer, A., et al. Autophagy in idiopathic pulmonary fibrosis. PLoS One, 7, 2012, e41394.
-
(2012)
PLoS One
, vol.7
, pp. e41394
-
-
Patel, A.S.1
Lin, L.2
Geyer, A.3
-
64
-
-
33845480131
-
Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response
-
[64] Bernales, S., McDonald, K.L., Walter, P., Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response. Plos Biol, 4, 2006, e423.
-
(2006)
Plos Biol
, vol.4
, pp. e423
-
-
Bernales, S.1
McDonald, K.L.2
Walter, P.3
-
65
-
-
84961290427
-
PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis
-
[65] Bueno, M., Lai, Y.C., Romero, Y., et al. PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis. J Clin Invest 125 (2015), 521–538.
-
(2015)
J Clin Invest
, vol.125
, pp. 521-538
-
-
Bueno, M.1
Lai, Y.C.2
Romero, Y.3
-
66
-
-
84925433501
-
Epithelial cell mitochondrial dysfunction and PINK1 are induced by transforming growth factor-beta1 in pulmonary fibrosis
-
[66] Patel, A.S., Song, J.W., Chu, S.G., et al. Epithelial cell mitochondrial dysfunction and PINK1 are induced by transforming growth factor-beta1 in pulmonary fibrosis. PLoS One, 10, 2015, e0121246.
-
(2015)
PLoS One
, vol.10
, pp. e0121246
-
-
Patel, A.S.1
Song, J.W.2
Chu, S.G.3
-
67
-
-
84871913289
-
Insufficient autophagy in idiopathic pulmonary fibrosis
-
[67] Araya, J., Kojima, J., Takasaka, N., et al. Insufficient autophagy in idiopathic pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol 304 (2013), L56–L69.
-
(2013)
Am J Physiol Lung Cell Mol Physiol
, vol.304
, pp. L56-L69
-
-
Araya, J.1
Kojima, J.2
Takasaka, N.3
-
68
-
-
81455155091
-
Prognostic factors for idiopathic pulmonary fibrosis: clinical, physiologic, pathologic, and molecular aspects
-
[68] Lee, S.H., Shim, H.S., Cho, S.H., et al. Prognostic factors for idiopathic pulmonary fibrosis: clinical, physiologic, pathologic, and molecular aspects. Sarcoidosis Vasc Diffus Lung Dis 28 (2011), 102–112.
-
(2011)
Sarcoidosis Vasc Diffus Lung Dis
, vol.28
, pp. 102-112
-
-
Lee, S.H.1
Shim, H.S.2
Cho, S.H.3
|