Ski inhibits TGF-β/phospho-Smad3 signaling and accelerates hypertrophic differentiation in chondrocytes

Journal of Cellular Biochemistry

Volumn 113, Issue 6, 2012, Pages 2156-2166

  Kim, Kyung Ok ^a   Sampson, Erik R ^a   Maynard, Robert D ^a   O'Keefe, Regis J ^a   Chen, Di ^a   Drissi, Hicham ^b   Rosier, Randy N ^a   Hilton, Matthew J ^a   Zuscik, Michael J ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

CHONDROCYTE; ENDOCHONDRAL OSSIFICATION; HISTONE DEACETYLASE; Ski; Smad3; TGF

Indexed keywords

BETA ACTIN; CYCLIN D1; HISTONE DEACETYLASE; HISTONE DEACETYLASE 4; HISTONE DEACETYLASE 5; LAMIN B; ONCOPROTEIN; PROTEIN SKI; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; VORINOSTAT;

ANIMAL CELL; ARTICLE; CARTILAGE CELL; CELL DIFFERENTIATION; CELL MATURATION; CHICK EMBRYO; CONTROLLED STUDY; EMBRYO; GENE INDUCTION; HYPERTROPHY; MARKER GENE; NONHUMAN; OSTEOCALCIN GENE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TYPE X COLLAGEN GENE; UPREGULATION;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; CHICK EMBRYO; CHONDROCYTES; COLLAGEN TYPE X; CORE BINDING FACTOR ALPHA 1 SUBUNIT; CYCLIN D1; HISTONE DEACETYLASES; OSTEOCALCIN; PROTO-ONCOGENE PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 84859582234     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24089     Document Type: Article

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