Transcriptional repressor ZEB2 promotes terminal differentiation of CD8+ effector and memory T cell populations during infection

Journal of Experimental Medicine

Volumn 212, Issue 12, 2015, Pages 2027-2039

  Omilusik, Kyla D ^a   Adam Best, J ^a   Yu, Bingfei ^a   Goossens, Steven ^c,d   Weidemann, Alexander ^e   Nguyen, Jessica V ^a   Seuntjens, Eve ^f,k   Stryjewska, Agata ^f   Zweier, Christiane ^e   Roychoudhuri, Rahul ^g   Gattinoni, Luca ^g   Bird, Lynne M ^b   Higashi, Yujiro ^h   Kondoh, Hisato ⁱ   Huylebroeck, Danny ^f,j   Haigh, Jody ^c   Goldrath, Ananda W ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b RADY CHILDREN'S HOSPITAL   (United States)

^c MONASH UNIVERSITY   (Australia)

^d GHENT UNIVERSITY   (Belgium)

^e UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^f UNIVERSITY OF LEUVEN   (Belgium)

^g NATIONAL CANCER INSTITUTE   (United States)

^h INSTITUTE FOR DEVELOPMENTAL RESEARCH   (Japan)

ⁱ KYOTO SANGYO UNIVERSITY   (Japan)

^j ERASMUS MEDICAL CENTER   (Netherlands)

^k UNIVERSITY OF LIÈGE   (Belgium)

more..

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 7 RECEPTOR; MESSENGER RNA; NATURAL KILLER CELL LECTIN LIKE RECEPTOR; NATURAL KILLER CELL LECTIN LIKE RECEPTOR G1; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR T BET; TRANSCRIPTION FACTOR ZEB2; UNCLASSIFIED DRUG; HOMEODOMAIN PROTEIN; IMMUNOGLOBULIN RECEPTOR; KLRG1 PROTEIN, MOUSE; PROTEIN BINDING; T BOX TRANSCRIPTION FACTOR; T-BOX TRANSCRIPTION FACTOR TBX21; TRANSCRIPTOME; ZFHX1B PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD8+ T LYMPHOCYTE; CELL FATE; CELL SURVIVAL; CELLULAR IMMUNITY; CONTROLLED STUDY; E BOX ELEMENT; EFFECTOR CELL; FLOW CYTOMETRY; HAPLOINSUFFICIENCY; IMMUNOSTIMULATION; INFECTION; LOXP SITE; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE MIGRATION; MALE; MEMORY T LYMPHOCYTE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PERIPHERAL LYMPHOCYTE; PRIMARY INFECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SECONDARY INFECTION; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; DEFICIENCY; DNA MICROARRAY; GENETICS; HOST PATHOGEN INTERACTION; HUMAN; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; KNOCKOUT MOUSE; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; VIROLOGY;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; FLOW CYTOMETRY; HOMEODOMAIN PROTEINS; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNOLOGIC MEMORY; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN BINDING; RECEPTORS, IMMUNOLOGIC; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; T-BOX DOMAIN PROTEINS; T-LYMPHOCYTE SUBSETS; TRANSCRIPTOME;

EID: 84962658625     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20150194     Document Type: Article

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