Regulation of stem cell self-renewal and differentiation by Wnt and Notch are conserved throughout the adenoma-carcinoma sequence in the colon

Molecular Cancer

Volumn 12, Issue 1, 2013, Pages

  Prasetyanti, Pramudita R ^a   Zimberlin, Cheryl D ^a   Bots, Michael ^a   Vermeulen, Louis ^a,b   De Sousa E Melo, Felipe ^a   Medema, Jan P ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Adenoma; Colorectal cancer; Morphogenic pathways; Notch; Organoid cultures; Stem cells; Wnt

Indexed keywords

MUCIN 2; NOTCH RECEPTOR; WNT PROTEIN;

ANIMAL CELL; ARTICLE; CANCER STAGING; CANCER STEM CELL; CELL DIFFERENTIATION; CELL FATE; CELL RENEWAL; COLON ADENOMA; COLON CARCINOMA; GOBLET CELL; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; WNT SIGNALING PATHWAY;

MUS;

ADENOCARCINOMA; ADENOMA; ANIMALS; BETA CATENIN; CELL LINE, TUMOR; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; COLONIC NEOPLASMS; HOMEOSTASIS; HUMANS; MICE; MICE, TRANSGENIC; NEOPLASTIC STEM CELLS; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 84885820837     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-12-126     Document Type: Article

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