Expression of CCR2 by endothelial cells implications for MCP-1 mediated wound injury repair and in vivo inflammatory activation of endothelium

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 19, Issue 9, 1999, Pages 2085-2093

  Weber, Kim S C ^a,c   Nelson, Peter J ^a   Gröne, Hermann Joseph ^b   Weber, Christian ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c Inst Prophylaxe K   (Germany)

Author keywords

Chemokine receptors; Chemokines; Endothelial cells; Migration

Indexed keywords

BLOCKING ANTIBODY; CHEMOKINE RECEPTOR; INTERLEUKIN 8; MESSENGER RNA; MONOCLONAL ANTIBODY; MONOCYTE CHEMOTACTIC PROTEIN 1;

ANGIOGENESIS; ARTICLE; ATHEROSCLEROSIS; CELL INFILTRATION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENDOTHELIUM INJURY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; VASCULAR ENDOTHELIUM; WOUND HEALING;

EID: 0032877937     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.19.9.2085     Document Type: Article

References (47)

1. Folkman J, Klagsburn M. Angiogenic factors. Science. 1987;235: 442-447.
2. Risau W. Mechanisms of angiogenesis. Nature. 1997;386:671-674.
3. Ross R. The pathogenesis of atherosclerosis: A perspective for the 1990s. Nature. 1993;362:801-809.
4. Sholley MM, Gimbrone MA, Cotran RS. Cellular migration and replication in endothelial regeneration: A study using irradiated endothelial cultures. Lab Invest. 1977;36:18-25.
5. Coomber BL, Gotlieb AI. In vitro endothelial wound repair: interaction of cell migration and proliferation. Arteriosclerosis. 1990;10:215-222.
6. Lindner V, Majacek RA, Reidy MR. Basic fibroblast growth factor stimulates endothelial regrowth and proliferation in denuded arteries. J Clin Invest. 1990;85:2004-2008.
7. Maione TE, Gray GS, Petro J, Hunt AJ, Donner AL, Bauer SI, Carson HF, Sharpe RJ. Inhibition of angiogenesis by recombinant human platelet faclor-4 and related peptides. Science. 1990;247:77-79.
8. Gupta SK, Hassel T, Singh JP. A potent inhibitor of endothelial cell proliferation is generated by proteolytic cleavage of the chemokine platelet factor 4. Proc Natl Acad Sci U S A. 1995;92:7799-7803.
9. Cao Y, Chen C, Weatherbee JA, Tsang M, Folkman J. Gro-β, a C-X-C chemokine, is an angiogenesis inhibitor that suppresses the growth of Lewis lung carcinoma in mice. J Exp Med. 1995;182:2069-2077.
10. Luster AD, Greenberg SM, Leder P. The IP-10 chemokine binds to a specific cell surface heparan sulfate site shared with platelet factor 4 and inhibits endothelial cell proliferation. J Exp Med. 1995;182:219-231.
11. Strieter RM, Polverini PJ, Kunkel SL, Arenberg DA, Burdick MD, Kasper J, Dzuiba J, Van Damme J, Walz A, Marriot D, Chan S-Y, Rocznial S, Shanafelt AB. The functional role of the ELR motif in CXC chemokine-mediated angiogenesis. J Biol Chem. 1995;270: 27348-27357.
12. Koch AE, Polverini PJ, Kunkel SL, Harlow SL, DiPietro LA, Einer VM, Einer SG, Strieter RM. Interleukin-8 as a macrophage-derived mediator of angiogenesis. Science. 1992;258:1798-1801.
13. Schönbeck U, Brandt E, Peterson F, Flad H-D, Loppnow H. IL-8 specifically binds to endothelial but not to smooth muscle cells. J Immunol. 1995;154:2375-2383.
14. Baggiolini M, Dewald B, Moser B. Interleukin-8 and related chemotactic cytokines: CXC and CC chemokines. Adv Immunol. 1994;55:97-179.
15. Gerard C, Gerard NP. The pro-inflammatory seven-transmembrane segment receptors of the leukocyte. Curr Opin Immunol. 1994;6: 140-145.
16. Rollins BJ. Chemokines. Blood. 1997;90:909.
17. Luster AD. Chemokines: Chemotactic cytokines that mediate inflammation. N Engl J Med. 1998;338:436-445.
18. Sica A, Saccani A, Borsatti A, Power CA, Wells TNC, Luini W, Polentarutti N, Sozzani S, Mantovani A. Bacterial lipopolysaccharide rapidly inhibits expression of C-C chemokine receptors in human monocytes. J Exp Med. 1997;185:969-974.
19. Tangirala RK, Murao K, Quehenberger O. Regulation of expression of the human monocyte chemotactic protein-1 receptor (hCCR2) by cytokines. J Biol Chem. 1997;272:8050-8056.
20. Tiffany HL, Alkhatih G, Combadiere C, Berger EA, Murphy PM. CC chemokine receptors 1 and 3 are differentially regulated by IL-5 during maturation of eosinophilic HL-60 cells. J Immunol. 1998;160:1385-1392.
21. Nelken NA, Coughlin SR, Gordon D, Wilcox JN. Monocyte chemoattractant protein-1 in human atheromatous plaques. J Clin Invest. 1991; 88:1121-1127.
22. Ylä-Herttuala S, Lipton BA, Sarkioja ME, Yoshimura T, Leonard EJ, Witztum JL, Steinberg D. Expression of monocyte chemotactic protein-1 in macrophage-rich areas of human and rabbit atherosclerotic lesions. Proc Natl Acad Sci U S A. 1991;88:5252-5256.
23. Ito WD, Arras M, Winkler B, Scholz D, Schaper J, Schaper W. Monocyte chemotactic protein-1 increases collateral and peripheral conductance after femoral artery occlusion. Circ Res. 1997;80:829-837.
24. Haves IM, Jorda NJ, Towers S, Smith G, Paterson JR, Earnshaw JJ, Roach AG, Westwick J, Williams RJ. Human vascular smooth muscle cells express receptors for CC chemokines. Arterioscler Thromb Vasc Biol. 1998;18:397-403.
25. Weber C, Erl W, Pietsch A, Ströbel M, Ziegler-Heitbrock HWL, Weber PC. Antioxidants inhibit monocyte adhesion by suppressing nuclear factor-κB mobilization and induction of vascular cell adhesion molecule-1 in endothelial cells stimulated to generate radicals. Arterioscler Thromb. 1994;14:1665-1673.
26. 2-terminal residues. J Exp Med. 1995;181:631-640.
27. Weber C, Erl W, Pietsch A, Weber PC. Aspirin inhibits nuclear factor-κB mobilization and monocyte adhesion in stimulated human endothelial cells. Circulation. 1995;91:1914-1917.
28. Kähler CM, Kirchmaier R, Kaufmann G, Kähler ST, Reinisch N, Fischer-Colbrie R, Hogue-Angeletti R, Winkler H, Wiedermann CJ. Inhibition of proliferation and stimulation of migration of endothelial cells by secretoneurin in vitro. Arterioscler Thromb Vasc Biol. 1997;17:932-939.
29. Aepfelbacher M, Essler M, Huber E, Sugai M, Weber PC. Bacterial toxins block endothelial wound repair. Evidence that rho GTPases control cytoskeletal rearrangements in migrating endothelial cells. Arterioscler Thromb Vasc Biol. 1997;17:1623-1629.
30. Frade JMR, Mellado M, del Real G, Gutierrez-Ramos JC, Lind P, Martinez-A C. Characterization of the CCR2 chemokine receptor: functional CCR2 receptor expression in B cells. J Immunol. 1997;159: 5576-5584.
31. Mellado M, Rodriguez-Frade JM, Aragay A, del Real G, Martin AM, Vila-Coro AJ, Serrano A, Mayor F, Martinez-A. C. The chemokine monocyte chemotactic protein 1 triggers janus kinase 2 activation and tyrosine phosphorylation of CCR2B receptor. J Immunol. 1998;161: 805-813.
32. Qin S, LaRosa G, Campbell JJ, Smith-Heath H, Kassam N, Shi X, Zheng L, Butcher EC, Mackay CR. Expression of monocyte chemoattractant protein-1 and interleukin-8 receptors on subsets of T cells: Correlation with transendothelial chemotactic potential. Eur J Immunol. 1996;26: 640-647.
33. Charo IF, Meyers SJ, Herman A, Franci C. Connolly AJ, Coughlin SR. Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxy-terminal tails. Proc Natl Acad Sci U S A. 1994;91:2752-2756.
34. Weber C, Lu CF, Casasnovas J, Springer TA. Role of αLβ2 integrin avidity in transendothelial chemotaxis of mononuclear cells. J Immunol. 1997;159:3968-3975.
35. Yoshimura T, Leonard EJ. Identification of high affinity receptors for human monocyte chemoattractant protein-1 on human monocytes. J Immunol. 1990;145:292-297.
36. Sozzani S, Luni W, Molino M, Jilek P, Bottazzi B, Cerletti C, Matsushima K, Mantovani A. The signal transduction pathway involved in the migration induced by a monocyte chemotactic cytokine. J Immunol. 1991;14: 2215-2221.
37. Wempe F, Lindner V, Augustin HG. Basic fibroblast growth factor (bFGF) regulates the expression of the CC chemokine monocyte chemoattractant protein-1 (MCP-1) in autocrine-activated endothelial cells. Arterioscler Vasc Biol Thromb. 1997;17:2471-2478.
38. Gupta S, Lysko PG, Pillarisetti K, Ohlstein E, Stadel JM. Chemokine receptors in human endothelial cells. Functional expression of CXCR4 and its transcriptional regulation by inflammatory cytokines. J Biol Chem. 1998;273:4282-4287.
39. Volin MV, Joseph L, Shockley MS, Davies PF. Chemokine receptor CXCR4 expression in endothelium. Biochem Biophys Res Commun. 1998;242:46-53.
40. Feil C, Augustin HG. Endothelial cells differentially express functional CXC-chemokine receptor-4 (CXCR4/fusin) under the control of autocrine activity and exogenous cytokines. Biochem Biophys Res Commun. 1998;247:38-45.
41. Watson CA, Camera-Benson L, Palmer-Crocker R, Pober JS. Variability among human umbilical vein endothelial cultures. Science. 1995;268: 447-448.
42. Carlevaro MF, Albini A, Ribatti D, Gentili C, Benelli R, Cermelli S, Cancedda R, Cancedda FD. Transferrin promotes endothelial cell migration and invasion: Implication in cartilage neovascularization. J Cell Biol. 1997;136:1375-1384.
43. DiPietro LA, Burdick M, Low QE, Kunkel SL, Strieter RM. MIP-1α as a critical macrophage chemoattractant in murine wound repair. J Clin Invest. 1998;101:1693-1698.
44. DiPietro LA, Polverini PJ, Rahbe SM, Kovacs EJ. Modulation of JE/MCP-1 expression in dermal wound repair. Am J Pathol. 1995;146: 868-875.
45. Stark VK, Hoch JR, Warner TF, Hullet DA. Monocyte chemotactic protein-1 expression is associated with the development of vein graft intimal hyperplasia. Arterioscler Thromb Vasc Biol. 1997;17:1614-1621.
46. Baggiolini M, Moser BM. Blocking chemokine receptors. J Exp Med. 1997;186:1189-1191.
47. Gong JH, Ratkay LG, Waterfield JD, Clark-Lewis I. An antagonist of monocyte chemoattractant protein 1 (MCP-1) inhibits arthritis in the MRL-lpr mouse model. J Exp Med. 1997;186:131-137.