Bidirectional modulation of thermal and chemical sensitivity of TRPM8 channels by the initial region of the N-terminal domain

Journal of Biological Chemistry

Volumn 289, Issue 32, 2014, Pages 21828-21843

  Pertusa, María ^a,b   González, Alejandro ^a   Hardy, Paulina ^a   Madrid, Rodolfo ^a   Viana, Félix ^b  

^a UNIVERSIDAD DE SANTIAGO DE CHILE   (Chile)

^b INSTITUTO DE NEUROCIENCIAS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGY;

BI-DIRECTIONAL MODULATION; CHEMICAL SENSITIVITY; N TERMINUS; N-TERMINAL DOMAINS;

SENSITIVITY ANALYSIS;

AVIAN PROTEIN; HYBRID PROTEIN; ISOPROTEIN; MENTHOL; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRPM2 PROTEIN, MOUSE; TRPM8 PROTEIN, HUMAN; TRPM8 PROTEIN, MOUSE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL; CHANNEL GATING; CHEMISTRY; CHICKEN; COLD; DRUG EFFECTS; GENE DELETION; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; MOLECULAR GENETICS; MOUSE; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; AVIAN PROTEINS; CHICKENS; COLD TEMPERATURE; HEK293 CELLS; HUMANS; ION CHANNEL GATING; MENTHOL; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SEQUENCE DELETION; TRPM CATION CHANNELS;

EID: 84905821341     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.565994     Document Type: Article

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