Phosphorylation of TRPV1 by cyclin-dependent kinase 5 promotes TRPV1 surface localization, leading to inflammatory thermal hyperalgesia

Experimental Neurology

Volumn 273, Issue , 2015, Pages 253-262

  Liu, Jiao ^a,b   Du, Junxie ^c   Yang, Yanrui ^d   Wang, Yun ^a,b  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b PEKING UNIVERSITY   (China)

^c XINGTAI UNIVERSITY   (China)

^d INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY   (China)

Author keywords

Cdk5; Hyperalgesia; Membrane trafficking; Phosphorylation; TRPV1

Indexed keywords

ALANINE; CYCLIN DEPENDENT KINASE 5; VANILLOID RECEPTOR 1; CALCIUM; CDK5R1 PROTEIN, RAT; FREUND ADJUVANT; KIF13B PROTEIN, RAT; KINESIN; PEPTIDE; PHOSPHOTRANSFERASE; THREONINE; TRPV1 PROTEIN, RAT; VANILLOID RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; HEAT SENSITIVITY; HYPERALGESIA; INFLAMMATORY THERMAL HYPERALGESIA; MALE; MUTATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT; SPINAL GANGLION; SURFACE PROPERTY; ANIMAL; CELL CULTURE; CHEMICALLY INDUCED; COMPLICATION; CYTOLOGY; DISEASE MODEL; GENETICS; HUMAN; INFLAMMATION; METABOLISM; NERVE CELL; PHOSPHORYLATION; SPRAGUE DAWLEY RAT;

ALANINE; ANIMALS; CALCIUM; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE 5; DISEASE MODELS, ANIMAL; FREUND'S ADJUVANT; GANGLIA, SPINAL; HUMANS; HYPERALGESIA; INFLAMMATION; KINESIN; MALE; MUTATION; NEURONS; PEPTIDES; PHOSPHORYLATION; PHOSPHOTRANSFERASES; RATS; RATS, SPRAGUE-DAWLEY; THREONINE; TRPV CATION CHANNELS;

EID: 84941948652     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2015.09.005     Document Type: Article

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