Simultaneous fermentation of glucose and xylose at elevated temperatures co-produces ethanol and xylitol through overexpression of a xylose-specific transporter in engineered Kluyveromyces marxianus

Bioresource Technology

Volumn 216, Issue , 2016, Pages 227-237

  Zhang, Biao ^a   Zhang, Jia ^a   Wang, Dongmei ^a   Han, Ruixiang ^c   Ding, Rui ^c   Gao, Xiaolian ^a,b   Sun, Lianhong ^a   Hong, Jiong ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b University of Houston   (United States)

^c ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Elevated temperature; Ethanol; SSCF; Xylitol; Xylose specific transporter

Indexed keywords

ETHANOL; FERMENTATION; GLUCOSE; SACCHARIFICATION;

COFERMENTATION; ELEVATED TEMPERATURE; KLUYVEROMYCES MARXIANUS; OVER-EXPRESSION; SIMULTANEOUS SACCHARIFICATION AND CO-FERMENTATION; SSCF; XYLITOL;

SUGAR SUBSTITUTES;

ACETIC ACID; ALCOHOL; CELLULASE; FURFURAL; GLUCOSE; GLYCEROL; XYLITOL; XYLOSE; CARRIER PROTEIN; GLYCEROL 3 PHOSPHATE DEHYDROGENASE (NAD);

ACETATE; BIOENGINEERING; ETHANOL; FERMENTATION; GENE EXPRESSION; HIGH TEMPERATURE; SUGAR; YEAST;

ALCOHOL PRODUCTION; ARTICLE; CONTROLLED STUDY; DNA MODIFICATION; FERMENTATION; KLUYVEROMYCES MARXIANUS; METABOLISM; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SACCHARIFICATION; TEMPERATURE; BIOSYNTHESIS; GENETIC ENGINEERING; GENETICS; KLUYVEROMYCES; MAIZE; MICROBIOLOGY; MUTATION; PROCEDURES; SACCHAROMYCES CEREVISIAE;

KLUYVEROMYCES MARXIANUS;

ETHANOL; FERMENTATION; GENETIC ENGINEERING; GLUCOSE; GLYCEROL; GLYCEROL-3-PHOSPHATE DEHYDROGENASE (NAD+); INDUSTRIAL MICROBIOLOGY; KLUYVEROMYCES; MEMBRANE TRANSPORT PROTEINS; MUTATION; SACCHAROMYCES CEREVISIAE; TEMPERATURE; XYLITOL; XYLOSE; ZEA MAYS;

EID: 84969939687     PISSN: 09608524     EISSN: 18732976     Source Type: Journal    
DOI: 10.1016/j.biortech.2016.05.068     Document Type: Article

References (33)

1. Abdel-Banat B.M.A., Nonklang S., Hoshida H., Akada R. Random and targeted gene integrations through the control of non-homologous end joining in the yeast Kluyveromyces marxianus. Yeast 2010, 27:29-39.
2. Alvira P., Tomas-Pejo E., Ballesteros M., Negro M.J. Pretreatment technologies for an efficient bioethanol production process based on enzymatic hydrolysis: a review. Bioresour. Technol. 2010, 101:4851-4861.
3. Banat I.M., Marchant R. Characterization and potential industrial applications of 5 novel, thermotolerant, fermentative, yeast strains. World J. Microbiol. Biotechnol. 1995, 11:304-306.
4. Cheng K.K., Wu J., Lin Z.N., Zhang J.A. Aerobic and sequential anaerobic fermentation to produce xylitol and ethanol using non-detoxified acid pretreated corncob. Biotechnol. Biofuels 2014, 7:166.
5. Farwick A., Bruder S., Schadeweg V., Oreb M., Boles E. Engineering of yeast hexose transporters to transport d-xylose without inhibition by d-glucose. Proc. Natl. Acad. Sci. U.S.A. 2014, 111:5159-5164.
6. Fonseca G.G., Heinzle E., Wittmann C., Gombert A.K. The yeast Kluyveromyces marxianus and its biotechnological potential. Appl. Microbiol. Biotechnol. 2008, 79:339-354.
7. Guo X.X., Zhang R.H., Li Z., Dai D.Z., Li C., Zhou X.H. A novel pathway construction in Candida tropicalis for direct xylitol conversion from corncob xylan. Bioresour. Technol. 2013, 128:547-552.
8. Ha S.J., Galazka J.M., Kim S.R., Choi J.H., Yang X., Seo J.H., Glass N.L., Cate J.H., Jin Y.S. Engineered Saccharomyces cerevisiae capable of simultaneous cellobiose and xylose fermentation. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:504-509.
9. He Y.L., Li M.M., Wu L.Y., Zhao T., Di Y., Huang X., Ding X.F., Wu K.W., Fan M., Zhu L.L. Enhanced hypoxia-inducible factor (HIF)-1alpha stability induced by 5-hydroxymethyl-2-furfural (5-HMF) contributes to protection against hypoxia. Mol. Med. 2014, 20:590-600.
10. Hickert L.R., de Souza-Cruz P.B., Rosa C.A., Ayub M.A. Simultaneous saccharification and co-fermentation of un-detoxified rice hull hydrolysate by Saccharomyces cerevisiae ICV D254 and Spathaspora arborariae NRRL Y-48658 for the production of ethanol and xylitol. Bioresour. Technol. 2013, 143:112-116.
11. Hong J., Wang Y., Kumagai H., Tamaki H. Construction of thermotolerant yeast expressing thermostable cellulase genes. J. Biotechnol. 2007, 130:114-123.
12. Hu C.M., Wu S.G., Wang Q., Jin G.J., Shen H.W., Zhao Z.B.K. Simultaneous utilization of glucose and xylose for lipid production by Trichosporon cutaneum. Biotechnol. Biofuels 2011, 4:25.
13. Kieke M.C., Shusta E.V., Boder E.T., Teyton L., Wittrup K.D., Kranz D.M. Selection of functional T cell receptor mutants from a yeast surface-display library. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:5651-5656.
14. + symporter. Biochem. J. 2006, 395:543-549.
15. Li Z., Qu H., Li C., Zhou X. Direct and efficient xylitol production from xylan by Saccharomyces cerevisiae through transcriptional level and fermentation processing optimizations. Bioresour. Technol. 2013, 149C:413-419.
16. Martinez A., Rodriguez M.E., York S.W., Preston J.F., Ingram L.O. Effects of Ca(OH)(2) treatments ("overliming") on the composition and toxicity of bagasse hemicellulose hydrolysates. Biotechnol. Bioeng. 2000, 69:526-536.
17. Nduko J.M., Matsumoto K., Ooi T., Taguchi S. Effectiveness of xylose utilization for high yield production of lactate-enriched P(lactate-co-3-hydroxybutyrate) using a lactate-overproducing strain of Escherichia coli and an evolved lactate-polymerizing enzyme. Metab. Eng. 2013, 15:159-166.
18. Nijland J.G., Shin H.Y., de Jong R.M., de Waal P.P., Klaassen P., Driessen A.J. Engineering of an endogenous hexose transporter into a specific d-xylose transporter facilitates glucose-xylose co-consumption in Saccharomyces cerevisiae. Biotechnol. Biofuels 2014, 7:168.
19. Oh E.J., Ha S.J., Kim S.R., Lee W.H., Galazka J.M., Cate J.H.D., Jin Y.S. Enhanced xylitol production through simultaneous co-utilization of cellobiose and xylose by engineered Saccharomyces cerevisiae. Metab. Eng. 2013, 15:226-234.
20. Pal S., Choudhary V., Kumar A., Biswas D., Mondal A.K., Sahoo D.K. Studies on xylitol production by metabolic pathway engineered Debaryomyces hansenii. Bioresour. Technol. 2013, 147:449-455.
21. Prakash G., Varma A.J., Prabhune A., Shouche Y., Rao M. Microbial production of xylitol from d-xylose and sugarcane bagasse hemicellulose using newly isolated thermotolerant yeast Debaryomyces hansenii. Bioresour. Technol. 2011, 102:3304-3308.
22. Suriyachai N., Weerasaia K., Laosiripojana N., Champreda V., Unrean P. Optimized simultaneous saccharification and co-fermentation of rice straw for ethanol production by Saccharomyces cerevisiae and Scheffersomyces stipitis co-culture using design of experiments. Bioresour. Technol. 2013, 142:171-178.
23. Verbeke T.J., Dumonceaux T.J., Wushke S., Cicek N., Levin D.B., Sparling R. Isolates of Thermoanaerobacter thermohydrosulfuricus from decaying wood compost display genetic and phenotypic microdiversity. FEMS Microbiol. Ecol. 2011, 78:473-487.
24. Wang M., Yu C., Zhao H. Directed evolution of xylose specific transporters to facilitate glucose-xylose co-utilization. Biotechnol. Bioeng. 2015, 113:484-491.
25. Wei N., Xu H., Kim S.R., Jin Y.S. Deletion of FPS1, encoding aquaglyceroporin Fps1p, improves xylose fermentation by engineered Saccharomyces cerevisiae. Appl. Environ. Microbiol. 2013, 79:3193-3201.
26. Xiong M., Chen G., Barford J. Alteration of xylose reductase coenzyme preference to improve ethanol production by Saccharomyces cerevisiae from high xylose concentrations. Bioresour. Technol. 2011, 102:9206-9215.
27. Zeng W., Li W., Shu L., Yi J., Chen G., Liang Z. Non-sterilized fermentative co-production of poly(gamma-glutamic acid) and fibrinolytic enzyme by a thermophilic Bacillus subtilis GXA-28. Bioresour. Technol. 2013, 142:697-700.
28. Zhang B., Zhang L., Wang D., Gao X., Hong J. Identification of a xylose reductase gene in the xylose metabolic pathway of Kluyveromyces marxianus NBRC1777. J. Ind. Microbiol. Biotechnol. 2011, 38:2001-2010.
29. Zhang B., Li L.L., Zhang J., Gao X.L., Wang D.M., Hong J. Improving ethanol and xylitol fermentation at elevated temperature through substitution of xylose reductase in Kluyveromyces marxianus. J. Ind. Microbiol. Biotechnol. 2013, 40:305-316.
30. Zhang J., Zhang B., Wang D.M., Gao X.L., Hong J. Xylitol production at high temperature by engineered Kluyveromyces marxianus. Bioresour. Technol. 2014, 152:192-201.
31. Zhang J., Zhang B., Wang D.M., Gao X.L., Hong J. Improving xylitol production at elevated temperature with engineered Kluyveromyces marxianus through over-expressing transporters. Bioresour. Technol. 2015, 175:642-645.
32. Zhang J., Zhang B., Wang D.M., Gao X.L., Sun L.H., Hong J. Rapid ethanol production at elevated temperatures by engineered thermotolerant Kluyveromyces marxianus via the NADP(H)-preferring xylose reductase-xylitol dehydrogenase pathway. Metab. Eng. 2015, 31:140-152.
33. Zhu J.Q., Qin L., Li B.Z., Yuan Y.J. Simultaneous saccharification and co-fermentation of aqueous ammonia pretreated corn stover with an engineered Saccharomyces cerevisiae SyBE005. Bioresour. Technol. 2014, 169:9-18.