A role for HOX13 proteins in the regulatory switch between TADs at the HoxD locus

Genes and Development

Volumn 30, Issue 10, 2016, Pages 1172-1186

  Beccari, Leonardo ^a   Yakushiji Kaminatsui, Nayuta ^b   Woltering, Joost M ^a,d   Necsulea, Anamaria ^b   Lonfat, Nicolas ^b,e   Rodríguez Carballo, Eddie ^a   Mascrez, Benedicte ^a   Yamamoto, Shiori ^c   Kuroiwa, Atsushi ^c   Duboule, Denis ^a,b  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b EPFL   (Switzerland)

^c NAGOYA UNIVERSITY   (Japan)

^d UNIVERSITY OF KONSTANZ   (Germany)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Ankle; Polycomb; Regulatory landscapes; Topologically associating domains (TADs); Vertebrate limbs; Wrist

Indexed keywords

HOX PROTEIN; PROTEIN HOX13; PROTEIN HOXD10; UNCLASSIFIED DRUG; HOMEODOMAIN PROTEIN; PROTEIN BINDING;

ANIMAL TISSUE; ARTICLE; CHICK EMBRYO; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ENHANCER REGION; GENE CONTROL; GENE EXPRESSION REGULATION; GENE INTERACTION; GENE LOCUS; HOX GENE; HOXD GENE; LIMB BUD; LIMB DEVELOPMENT; LOSS OF FUNCTION MUTATION; MOUSE; MOUSE EMBRYO; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; RNA SEQUENCE; TELOMERE; TOPOLOGICALLY ASSOCIATING DOMAIN; WILD TYPE; ANIMAL; EMBRYOLOGY; GENETICS; HOMEOBOX; LIMB; LIMB MALFORMATION; METABOLISM; MORPHOGENESIS; MUTATION; TRANSGENIC MOUSE;

ANIMALS; BODY PATTERNING; CHICK EMBRYO; ENHANCER ELEMENTS, GENETIC; EXTREMITIES; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, HOMEOBOX; HOMEODOMAIN PROTEINS; LIMB DEFORMITIES, CONGENITAL; MICE; MICE, TRANSGENIC; MUTATION; PROTEIN BINDING; PROTEIN DOMAINS;

EID: 84969751566     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.281055.116     Document Type: Article

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