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Volumn 43, Issue 4, 1999, Pages 287-294

Altered Hox expression and increased cell death distinguish Hypodactyly from Hoxa13 null mice

Author keywords

Cell death; Hoxa13; Hypodactyly; Limb development

Indexed keywords

ANIMAL CELL; ARTICLE; CELL DEATH; CROSSING OVER; GENE DELETION; GENE EXPRESSION; GENE MUTATION; GENE SEQUENCE; IN SITU HYBRIDIZATION; LIMB BUD; LIMB DEVELOPMENT; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

EID: 0032815694     PISSN: 02146282     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (35)

References (36)
  • 1
    • 0027375604 scopus 로고
    • Mice homozygous for a targeted disruption of Hoxd-3 (Hox-4.1) exhibit anterior transformations of the first and second cervical vertebrae, the atlas, and the axis
    • CONDIE, B.G. and CAPECCHI, M.R. (1993). Mice homozygous for a targeted disruption of Hoxd-3 (Hox-4.1) exhibit anterior transformations of the first and second cervical vertebrae, the atlas, and the axis. Development 119: 579-595.
    • (1993) Development , vol.119 , pp. 579-595
    • Condie, B.G.1    Capecchi, M.R.2
  • 2
    • 0028124772 scopus 로고
    • Mice with targeted disruptions in the paralogous genes Hoxa-3 and hoxd-3 reveal synergistic interactions
    • CONDIE, B.G. and CAPECCHI, M.R. (1994). Mice with targeted disruptions in the paralogous genes Hoxa-3 and hoxd-3 reveal synergistic interactions. Nature 370: 304-307.
    • (1994) Nature , vol.370 , pp. 304-307
    • Condie, B.G.1    Capecchi, M.R.2
  • 3
    • 0027454373 scopus 로고
    • Detection of messenger RNA by in situ hybridization to postimplantation embryo whole mounts
    • Eds. P.M. Wasserman and M.L. DePamphilis, Academic Press, Inc, San Diego
    • CONLON, R.A. and HERRMANN, B.G. (1993). Detection of messenger RNA by in situ hybridization to postimplantation embryo whole mounts. In Guide to techniques in mouse development (Eds. P.M. Wasserman and M.L. DePamphilis), Vol. 225, Academic Press, Inc, San Diego. pp 373-383.
    • (1993) Guide to Techniques in Mouse Development , vol.225 , pp. 373-383
    • Conlon, R.A.1    Herrmann, B.G.2
  • 4
    • 0028959288 scopus 로고
    • The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo
    • CROSSLEY, P. and MARTIN, G.R. (1995). The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo. Development 121: 439-451.
    • (1995) Development , vol.121 , pp. 439-451
    • Crossley, P.1
  • 5
    • 0028085623 scopus 로고
    • Axial homeosis and appendicular skeleton defects in mice with a targeted disruption of hoxd-11
    • DAVIS, A.P. and CAPECCHI, M.R. (1994). Axial homeosis and appendicular skeleton defects in mice with a targeted disruption of hoxd-11. Development 120: 2187-2198.
    • (1994) Development , vol.120 , pp. 2187-2198
    • Davis, A.P.1    Capecchi, M.R.2
  • 6
    • 0029963585 scopus 로고    scopus 로고
    • A mutational analysis of the 5′ HoxD genes: Dissection of genetic interactions during limb development in the mouse
    • DAVIS, A.P. and CAPECCHI, M.R. (1996). A mutational analysis of the 5′ HoxD genes: dissection of genetic interactions during limb development in the mouse. Development 122: 1175-1185.
    • (1996) Development , vol.122 , pp. 1175-1185
    • Davis, A.P.1    Capecchi, M.R.2
  • 7
    • 0029026767 scopus 로고
    • Absence of radius and ulna in mice lacking Hoxa-11 and hoxd-11
    • DAVIS, A.P., WITTE, D.P., HSIEH-LI, H.M., POTTER, S.S. and CAPECCHI, M.R. (1995). Absence of radius and ulna in mice lacking Hoxa-11 and hoxd-11. Nature 375: 791-795.
    • (1995) Nature , vol.375 , pp. 791-795
    • Davis, A.P.1    Witte, D.P.2    Hsieh-Li, H.M.3    Potter, S.S.4    Capecchi, M.R.5
  • 8
    • 0027358721 scopus 로고
    • Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs
    • DOLLE, P., DIERICH, A., LEMEUR, M., SCHIMMANG, T., SCHUHBAUR, B., CHAMBON, P. and DUBOULE, D. (1993). Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs. Cell 75: 431-441.
    • (1993) Cell , vol.75 , pp. 431-441
    • Dolle, P.1    Dierich, A.2    Lemeur, M.3    Schimmang, T.4    Schuhbaur, B.5    Chambon, P.6    Duboule, D.7
  • 9
    • 0026326323 scopus 로고
    • The Hox-4.8 gene is localized at the 5′ extremity of the Hox-4 complex and is expressed in the most posterior parts of the body during development
    • DOLLE, P., IZPISUA-BELMONTE, J.-C., BONCINELLI, E. and DUBOULE, D. (1991). The Hox-4.8 gene is localized at the 5′ extremity of the Hox-4 complex and is expressed in the most posterior parts of the body during development. Mech. Dev. 36: 3-13.
    • (1991) Mech. Dev. , vol.36 , pp. 3-13
    • Dolle, P.1    Izpisua-Belmonte, J.-C.2    Boncinelli, E.3    Duboule, D.4
  • 10
    • 0028266824 scopus 로고
    • FGF-2: Apical ectodermal ridge growth signal for chick limb development
    • FALLON, J.F., LOPEZ, A., ROS, M.A., SAVAGE, M.P., OLWIN, B.B. and SIMANDL, B.K. (1994). FGF-2: Apical ectodermal ridge growth signal for chick limb development. Science 264: 104-107.
    • (1994) Science , vol.264 , pp. 104-107
    • Fallon, J.F.1    Lopez, A.2    Ros, M.A.3    Savage, M.P.4    Olwin, B.B.5    Simandl, B.K.6
  • 12
    • 0029831470 scopus 로고    scopus 로고
    • Role of TGFbs and BMPs as signals controlling the position of the digits and the areas of interdigital cell death in the developing chick limb autopod
    • GANAN, Y., MACIAS, D., DUTERQUE-COQUILLAUD, M., ROS, M.A. and HURLÉ, J.M. (1996). Role of TGFbs and BMPs as signals controlling the position of the digits and the areas of interdigital cell death in the developing chick limb autopod. Development 122: 2349-2357.
    • (1996) Development , vol.122 , pp. 2349-2357
    • Ganan, Y.1    Macias, D.2    Duterque-Coquillaud, M.3    Ros, M.A.4    Hurlé, J.M.5
  • 13
    • 0031043604 scopus 로고    scopus 로고
    • Analysis of Hoxd-13 and Hoxd-11 misexpression in chick limb buds reveals that Hox genes affect both bone condensation and growth
    • GOFF, D.J. and TABIN, C.J. (1997). Analysis of Hoxd-13 and Hoxd-11 misexpression in chick limb buds reveals that Hox genes affect both bone condensation and growth. Development 124: 627-636.
    • (1997) Development , vol.124 , pp. 627-636
    • Goff, D.J.1    Tabin, C.J.2
  • 14
    • 0027264967 scopus 로고
    • The establishment of murine Hox-1 expression domains during patterning of the limb
    • HAACK, H. and GRUSS, P. (1993). The establishment of murine Hox-1 expression domains during patterning of the limb. Dev. Biol. 157: 410-422.
    • (1993) Dev. Biol. , vol.157 , pp. 410-422
    • Haack, H.1    Gruss, P.2
  • 15
    • 0014846558 scopus 로고
    • Hypodactyly, a semidominant lethal mutation in mice
    • HUMMEL, K.P. (1970). Hypodactyly, a semidominant lethal mutation in mice. J. Hered. 61: 219-220.
    • (1970) J. Hered. , vol.61 , pp. 219-220
    • Hummel, K.P.1
  • 16
    • 0029678267 scopus 로고    scopus 로고
    • High resolution genetic mapping of the Hypodactyly (Hd) locus on mouse chromosome 6
    • INNIS, J.W., KAZEN-GILLESPIE, K., POST, L.C. and MCGORMAN, J. (1996). High resolution genetic mapping of the Hypodactyly (Hd) locus on mouse chromosome 6. Mammal. Genome 7: 2-5.
    • (1996) Mammal. Genome , vol.7 , pp. 2-5
    • Innis, J.W.1    Kazen-Gillespie, K.2    Post, L.C.3    Mcgorman, J.4
  • 17
    • 84907134943 scopus 로고
    • A rapid procedure for routine double staining of cartilage and bone in fetal and adult animals
    • KIMMEL, C.A. and TRAMMEL, C. (1981). A rapid procedure for routine double staining of cartilage and bone in fetal and adult animals. Stain Technol. 56: 271-273.
    • (1981) Stain Technol. , vol.56 , pp. 271-273
    • Kimmel, C.A.1    Trammel, C.2
  • 18
    • 1842405367 scopus 로고    scopus 로고
    • Role of BMP-2 and OP-1 (BMP-7) in programmed cell death and skeletogenesis during chick limb development
    • MACIAS, D., GANAN, Y., SAMPATH, T.K., PIEDRA, M.E., ROS, M.A. and HURLÉ, J.M. (1997). Role of BMP-2 and OP-1 (BMP-7) in programmed cell death and skeletogenesis during chick limb development. Development 124: 1109-1117.
    • (1997) Development , vol.124 , pp. 1109-1117
    • Macias, D.1    Ganan, Y.2    Sampath, T.K.3    Piedra, M.E.4    Ros, M.A.5    Hurlé, J.M.6
  • 19
    • 0026539589 scopus 로고
    • A new interpretation of the necrotic changes occurring in the developing limb bud paddle of mouse embryos based upon recent observation in four different phenotypes
    • MILAIRE, J. (1992). A new interpretation of the necrotic changes occurring in the developing limb bud paddle of mouse embryos based upon recent observation in four different phenotypes. Int. J. Dev. Biol. 36: 169-178.
    • (1992) Int. J. Dev. Biol. , vol.36 , pp. 169-178
    • Milaire, J.1
  • 20
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • MILLER, S., DYKES, D. and POLESKY, H. (1988). A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 16: 1215.
    • (1988) Nucleic Acids Res. , vol.16 , pp. 1215
    • Miller, S.1    Dykes, D.2    Polesky, H.3
  • 21
    • 0023393722 scopus 로고
    • A mouse homeo box gene, Hox-1.5, and the morphological locus, Hd, map to within 1 cM on chromosome 6
    • MOCK, B.A., D'HOOSTELAERE, L.A., MATTHAI, R. and HUPPI, K. (1987). A mouse homeo box gene, Hox-1.5, and the morphological locus, Hd, map to within 1 cM on chromosome 6. Genetics 116: 607-612.
    • (1987) Genetics , vol.116 , pp. 607-612
    • Mock, B.A.1    D'Hoostelaere, L.A.2    Matthai, R.3    Huppi, K.4
  • 22
    • 0028576041 scopus 로고
    • Hox genes and growth: Early and late roles in limb bud morphogenesis
    • MORGAN, B.A. and TABIN, C. (1994). Hox genes and growth: early and late roles in limb bud morphogenesis. Development (Suppl.): 181-186.
    • (1994) Development (Suppl.) , pp. 181-186
    • Morgan, B.A.1    Tabin, C.2
  • 23
    • 0026780670 scopus 로고
    • Targeted misexpression of Hox-4.6 in the avian limb bud causes apparent homeotic transformations
    • MORGAN, B.A., IZPISUA-BELMONTE, J.-C., DUBOULE, D. and TABIN, C.J. (1992). Targeted misexpression of Hox-4.6 in the avian limb bud causes apparent homeotic transformations. Nature 358: 236-239.
    • (1992) Nature , vol.358 , pp. 236-239
    • Morgan, B.A.1    Izpisua-Belmonte, J.-C.2    Duboule, D.3    Tabin, C.J.4
  • 24
    • 0030002141 scopus 로고    scopus 로고
    • The molecular basis of Hypodactyly (Hd): A deletion in Hoxa 13 leads to arrest of digital arch formation
    • MORTLOCK, D.P., POST, L.C. and INNIS, J.W. (1996). The molecular basis of Hypodactyly (Hd): a deletion in Hoxa 13 leads to arrest of digital arch formation. Nature Genet. 13: 284-289.
    • (1996) Nature Genet. , vol.13 , pp. 284-289
    • Mortlock, D.P.1    Post, L.C.2    Innis, J.W.3
  • 25
    • 0027436330 scopus 로고
    • FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb
    • NISWANDER, L., TICKLE, C., VOGEL, A., BOOTH, I. and MARTIN, G.R. (1993). FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb. Cell 75: 579-587.
    • (1993) Cell , vol.75 , pp. 579-587
    • Niswander, L.1    Tickle, C.2    Vogel, A.3    Booth, I.4    Martin, G.R.5
  • 26
    • 0033042804 scopus 로고    scopus 로고
    • BMPs negatively regulate structure and function of the limb apical ectodermal ridge
    • PIZETTE, S. and NISWANDER, L. (1999). BMPs negatively regulate structure and function of the limb apical ectodermal ridge. Development 126: 883-894.
    • (1999) Development , vol.126 , pp. 883-894
    • Pizette, S.1    Niswander, L.2
  • 28
    • 0029773647 scopus 로고    scopus 로고
    • Cellular analysis of limb development in the mouse mutant Hypodactyly
    • ROBERTSON, K.E., ADAMS, A., TICKLE, C. and DARLING, S.M. (1996). Cellular analysis of limb development in the mouse mutant Hypodactyly. Dev. Genet. 19: 9-25.
    • (1996) Dev. Genet. , vol.19 , pp. 9-25
    • Robertson, K.E.1    Adams, A.2    Tickle, C.3    Darling, S.M.4
  • 29
    • 0030720099 scopus 로고    scopus 로고
    • Shh, Fgf4 and Hoxd gene expression in the mouse limb mutant Hypodactyly
    • ROBERTSON, K.E., TICKLE, C. and DARLING, S.M. (1997). Shh, Fgf4 and Hoxd gene expression in the mouse limb mutant Hypodactyly. Int. J. Dev. Biol. 41: 733-736.
    • (1997) Int. J. Dev. Biol. , vol.41 , pp. 733-736
    • Robertson, K.E.1    Tickle, C.2    Darling, S.M.3
  • 30
    • 84924843883 scopus 로고
    • The proximodistal sequence of origin on the parts of the chick wing and the role of the ectoderm
    • SAUNDERS, J.W. (1948). The proximodistal sequence of origin on the parts of the chick wing and the role of the ectoderm. J. Exp. Zool. 108: 363-403.
    • (1948) J. Exp. Zool. , vol.108 , pp. 363-403
    • Saunders, J.W.1
  • 31
    • 0027131262 scopus 로고
    • Homeotic transformations and limb defects in Hoxa 11 mutant mice
    • SMALL, K.M. and POTTER, S.S. (1993). Homeotic transformations and limb defects in Hoxa 11 mutant mice. Genes Dev. 7: 2318-2328.
    • (1993) Genes Dev. , vol.7 , pp. 2318-2328
    • Small, K.M.1    Potter, S.S.2
  • 32
    • 0016309037 scopus 로고
    • A quantitative analysis of the effect of excision of the AER from the chick limb bud
    • SUMMERBELL, D. (1974). A quantitative analysis of the effect of excision of the AER from the chick limb bud. J. Embryol. Exp. Morphol. 32: 651-660.
    • (1974) J. Embryol. Exp. Morphol. , vol.32 , pp. 651-660
    • Summerbell, D.1
  • 33
    • 0015803611 scopus 로고
    • Positional information in chick limb morphogenesis
    • SUMMERBELL, D., LEWIS, J.H. and WOLPERT, L. (1973). Positional information in chick limb morphogenesis. Nature 375: 492-496.
    • (1973) Nature , vol.375 , pp. 492-496
    • Summerbell, D.1    Lewis, J.H.2    Wolpert, L.3
  • 34
    • 0028973404 scopus 로고
    • Misexpression of Hoxa-13 induces cartilage homeotic transformation and changes cell adhesiveness in chick limb buds
    • YOKOUCHI, Y., NAKAZATO, S., YAMAMOTO, M., GOTO, Y., KAMEDA, T., IBA, H. and KUROIWA, A. (1995). Misexpression of Hoxa-13 induces cartilage homeotic transformation and changes cell adhesiveness in chick limb buds. Genes Dev. 9: 2509-2522.
    • (1995) Genes Dev. , vol.9 , pp. 2509-2522
    • Yokouchi, Y.1    Nakazato, S.2    Yamamoto, M.3    Goto, Y.4    Kameda, T.5    Iba, H.6    Kuroiwa, A.7
  • 36
    • 0031459462 scopus 로고    scopus 로고
    • Regulation of number and size of digits by posterior Hox genes: A dose-dependent mechanism with potential evolutionary implications
    • ZAKANY, J., FROMENTAL-RAMAIN, C., WAROT, X. and DUBOULE, D. (1997). Regulation of number and size of digits by posterior Hox genes: a dose-dependent mechanism with potential evolutionary implications. Proc. Natl. Acad. Sci. USA 94: 13695-13700.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 13695-13700
    • Zakany, J.1    Fromental-Ramain, C.2    Warot, X.3    Duboule, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.