Structure, function and evolution of topologically associating domains (TADs) at HOX loci

FEBS Letters

Volumn 589, Issue 20, 2015, Pages 2869-2876

  Lonfat, Nicolas ^a,c   Duboule, Denis ^a,b  

^a EPFL   (Switzerland)

^b UNIVERSITY OF GENEVA   (Switzerland)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Architecture; Digits; Enhancers; Evolution; External genitalia; Genital tubercle (GT); Hox genes; Intestinal cecum; Limbs; Pleiotropy; Regulation; Topologically associating domains (TADs)

Indexed keywords

HOX PROTEIN; HOMEODOMAIN PROTEIN;

ARTICLE; CECUM; CHROMATIN STRUCTURE; CIS ISOMER; CONFORMATIONAL TRANSITION; EVOLUTION; FINGER; GENE; GENE ACTIVATION; GENE CLUSTER; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; GENE INTERACTION; GENE LOCUS; GENE SEQUENCE; GENE SWITCHING; GENETIC TRANSCRIPTION; GENITAL SYSTEM; HOX GENE; HOXA GENE; HOXD GENE; HUMAN; LIMB DEVELOPMENT; NONHUMAN; ORGANOGENESIS; PLEIOTROPY; PRIORITY JOURNAL; TOPOLOGICALLY ASSOCIATING DOMAIN; ANIMAL; ANTIBODY SPECIFICITY; EMBRYO DEVELOPMENT; GENE EXPRESSION REGULATION; GENETICS; MOLECULAR EVOLUTION; MULTIGENE FAMILY;

ANIMALS; EMBRYONIC DEVELOPMENT; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETIC LOCI; GENETIC PLEIOTROPY; HOMEODOMAIN PROTEINS; HUMANS; MULTIGENE FAMILY; ORGAN SPECIFICITY;

EID: 84943348158     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2015.04.024     Document Type: Review

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