Hoxd-12 differentially affects preaxial and postaxial chondrogenic branches in the limb and regulates Sonic hedgehog in a positive feedback loop

Development

Volumn 124, Issue 22, 1997, Pages 4523-4536

  Knezevic, Vladimir ^a   De Santo, Ron ^a   Schughart, Klaus ^c,d   Huffstadt, Ulrike ^c   Chiang, Chin ^b   Mahon, Kathleen A ^b,e   Mackem, Susan ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d TRANSGENE S A   (France)

^e BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Chondrogenesis; Extra toes; Hoxd 12; Limb development; Luxate mutants; Luxoid mutants; Sonic hedgehog

Indexed keywords

FIBROBLAST GROWTH FACTOR; SONIC HEDGEHOG PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; CELL CULTURE; CHONDROGENESIS; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; EMBRYO; GENE EXPRESSION REGULATION; HOMEOBOX; LIMB DEVELOPMENT; MOUSE MUTANT; NONHUMAN; PELVIS; POLYDACTYLY; POSITIVE FEEDBACK; PRIORITY JOURNAL; STERNUM; TRANSACTIVATION; TRANSGENIC MOUSE;

ANIMALS; BASE SEQUENCE; BONE AND BONES; CARTILAGE; DNA; EXTREMITIES; FEEDBACK; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, HOMEOBOX; HEDGEHOG PROTEINS; HOMEODOMAIN PROTEINS; LIMB DEFORMITIES, CONGENITAL; MALE; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PHENOTYPE; PROMOTER REGIONS (GENETICS); PROTEINS; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

ANIMALIA; ERINACEIDAE; MUS MUSCULUS;

EID: 0030725128     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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