-
1
-
-
1842558956
-
Pathogenetic role of BCL6 translocation in B-cell non-Hodgkin's lymphoma
-
Ohno H. Pathogenetic role of BCL6 translocation in B-cell non-Hodgkin's lymphoma. Histol Histopathol 2004, 19:637-650.
-
(2004)
Histol Histopathol
, vol.19
, pp. 637-650
-
-
Ohno, H.1
-
2
-
-
37549015263
-
Germinal centres: role in B-cell physiology and malignancy
-
Klein U., Dalla-Favera R. Germinal centres: role in B-cell physiology and malignancy. Nat Rev Immunol 2008, 8:22-33.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 22-33
-
-
Klein, U.1
Dalla-Favera, R.2
-
3
-
-
47149096182
-
B-cell lymphoma 6 and the molecular pathogenesis of diffuse large B-cell lymphoma
-
Ci W., Polo J., Melnick A. B-cell lymphoma 6 and the molecular pathogenesis of diffuse large B-cell lymphoma. Curr Opin Hematol 2008, 15:381-390.
-
(2008)
Curr Opin Hematol
, vol.15
, pp. 381-390
-
-
Ci, W.1
Polo, J.2
Melnick, A.3
-
4
-
-
84859715609
-
Roles of BCL6 in normal and transformed germinal center B cells
-
Basso K., Dalla-Favera R. Roles of BCL6 in normal and transformed germinal center B cells. Immunol Rev 2012, 247:172-183.
-
(2012)
Immunol Rev
, vol.247
, pp. 172-183
-
-
Basso, K.1
Dalla-Favera, R.2
-
5
-
-
70049101558
-
The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment
-
Yu D., Rao S., Tsai L.M., Lee S.K., He Y., Sutcliffe E.L., Srivastava M., Linterman M., Zheng L., Simpson N., et al. The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment. Immunity 2009, 31:457-468.
-
(2009)
Immunity
, vol.31
, pp. 457-468
-
-
Yu, D.1
Rao, S.2
Tsai, L.M.3
Lee, S.K.4
He, Y.5
Sutcliffe, E.L.6
Srivastava, M.7
Linterman, M.8
Zheng, L.9
Simpson, N.10
-
6
-
-
69249101229
-
Bcl6 mediates the development of T follicular helper cells
-
Nurieva R.I., Chung Y., Martinez G.J., Yang X.O., Tanaka S., Matskevitch T.D., Wang Y.H., Dong C. Bcl6 mediates the development of T follicular helper cells. Science 2009, 325:1001-1005.
-
(2009)
Science
, vol.325
, pp. 1001-1005
-
-
Nurieva, R.I.1
Chung, Y.2
Martinez, G.J.3
Yang, X.O.4
Tanaka, S.5
Matskevitch, T.D.6
Wang, Y.H.7
Dong, C.8
-
7
-
-
69249109601
-
Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation
-
Johnston R.J., Poholek A.C., DiToro D., Yusuf I., Eto D., Barnett B., Dent A.L., Craft J., Crotty S. Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation. Science 2009, 325:1006-1010.
-
(2009)
Science
, vol.325
, pp. 1006-1010
-
-
Johnston, R.J.1
Poholek, A.C.2
DiToro, D.3
Yusuf, I.4
Eto, D.5
Barnett, B.6
Dent, A.L.7
Craft, J.8
Crotty, S.9
-
8
-
-
79952675131
-
Follicular helper CD4 T cells (TFH)
-
Crotty S. Follicular helper CD4 T cells (TFH). Annu Rev Immunol 2011, 29:621-663.
-
(2011)
Annu Rev Immunol
, vol.29
, pp. 621-663
-
-
Crotty, S.1
-
9
-
-
84255178198
-
Early Th1 cell differentiation is marked by a Tfh cell-like transition
-
Nakayamada S., Kanno Y., Takahashi H., Jankovic D., Lu K.T., Johnson T.A., Sun H., Vahedi G., Hakim O., Handon R., et al. Early Th1 cell differentiation is marked by a Tfh cell-like transition. Immunity 2011, 35:919-931.
-
(2011)
Immunity
, vol.35
, pp. 919-931
-
-
Nakayamada, S.1
Kanno, Y.2
Takahashi, H.3
Jankovic, D.4
Lu, K.T.5
Johnson, T.A.6
Sun, H.7
Vahedi, G.8
Hakim, O.9
Handon, R.10
-
10
-
-
84858706847
-
Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile
-
Oestreich K., Mohn S., Weinmann A. Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile. Nat Immunol 2012, 13:405-411.
-
(2012)
Nat Immunol
, vol.13
, pp. 405-411
-
-
Oestreich, K.1
Mohn, S.2
Weinmann, A.3
-
11
-
-
84859897308
-
The development and fate of follicular helper T cells defined by an IL-21 reporter mouse
-
Luthje K., Kallies A., Shimohakamada Y., Belz G.T., Light A., Tarlinton D.M., Nutt S.L. The development and fate of follicular helper T cells defined by an IL-21 reporter mouse. Nat Immunol 2012, 13:491-498.
-
(2012)
Nat Immunol
, vol.13
, pp. 491-498
-
-
Luthje, K.1
Kallies, A.2
Shimohakamada, Y.3
Belz, G.T.4
Light, A.5
Tarlinton, D.M.6
Nutt, S.L.7
-
12
-
-
34247387876
-
Repression of BCL-6 is required for the formation of human memory B cells in vitro
-
Kuo T.C., Shaffer A.L., Haddad J., Choi Y.S., Staudt L., Calame K. Repression of BCL-6 is required for the formation of human memory B cells in vitro. J Exp Med 2007, 204:819-830.
-
(2007)
J Exp Med
, vol.204
, pp. 819-830
-
-
Kuo, T.C.1
Shaffer, A.L.2
Haddad, J.3
Choi, Y.S.4
Staudt, L.5
Calame, K.6
-
13
-
-
80755172184
-
Opposing signals from the bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells
-
Pepper M., Pagán A.J., Igyártó B.Z., Taylor J.J., Jenkins M.K. Opposing signals from the bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells. Immunity 2011, 35:583-595.
-
(2011)
Immunity
, vol.35
, pp. 583-595
-
-
Pepper, M.1
Pagán, A.J.2
Igyártó, B.Z.3
Taylor, J.J.4
Jenkins, M.K.5
-
14
-
-
80755163540
-
Differential expression of Ly6C and T-bet distinguish effector and memory Th1 CD4(+) cell properties during viral infection
-
Marshall H.D., Chandele A., Jung Y.W., Meng H., Poholek A.C., Parish I.A., Rutishauser R., Cui W., Kleinstein S.H., Craft J., et al. Differential expression of Ly6C and T-bet distinguish effector and memory Th1 CD4(+) cell properties during viral infection. Immunity 2011, 35:633-646.
-
(2011)
Immunity
, vol.35
, pp. 633-646
-
-
Marshall, H.D.1
Chandele, A.2
Jung, Y.W.3
Meng, H.4
Poholek, A.C.5
Parish, I.A.6
Rutishauser, R.7
Cui, W.8
Kleinstein, S.H.9
Craft, J.10
-
15
-
-
84870285173
-
Bcl6 expression specifies the T follicular helper cell program in vivo
-
S1841-S1824
-
Liu X., Yan X., Zhong B., Nurieva R.I., Wang A., Wang X., Martin-Orozco N., Wang Y., Chang S.H., Esplugues E., et al. Bcl6 expression specifies the T follicular helper cell program in vivo. J Exp Med 2012, 209:1841-1852. S1841-S1824.
-
(2012)
J Exp Med
, vol.209
, pp. 1841-1852
-
-
Liu, X.1
Yan, X.2
Zhong, B.3
Nurieva, R.I.4
Wang, A.5
Wang, X.6
Martin-Orozco, N.7
Wang, Y.8
Chang, S.H.9
Esplugues, E.10
-
16
-
-
79961158055
-
Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions
-
Chung Y., Tanaka S., Chu F., Nurieva R.I., Martinez G.J., Rawal S., Wang Y., Lim H., Reynolds J.M., Zhou X., et al. Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions. Nat Med 2011, 17:983-988.
-
(2011)
Nat Med
, vol.17
, pp. 983-988
-
-
Chung, Y.1
Tanaka, S.2
Chu, F.3
Nurieva, R.I.4
Martinez, G.J.5
Rawal, S.6
Wang, Y.7
Lim, H.8
Reynolds, J.M.9
Zhou, X.10
-
17
-
-
79961151137
-
Foxp3(+) follicular regulatory T cells control the germinal center response
-
Linterman M.A., Pierson W., Lee S.K., Kallies A., Kawamoto S., Rayner T.F., Srivastava M., Divekar D.P., Beaton L., Hogan J.J., et al. Foxp3(+) follicular regulatory T cells control the germinal center response. Nat Med 2011, 17:975-982.
-
(2011)
Nat Med
, vol.17
, pp. 975-982
-
-
Linterman, M.A.1
Pierson, W.2
Lee, S.K.3
Kallies, A.4
Kawamoto, S.5
Rayner, T.F.6
Srivastava, M.7
Divekar, D.P.8
Beaton, L.9
Hogan, J.J.10
-
18
-
-
79961153751
-
T(reg) cells: patrolling a dangerous neighborhood
-
Campbell D.J., Koch M.A. T(reg) cells: patrolling a dangerous neighborhood. Nat Med 2011, 17:929-930.
-
(2011)
Nat Med
, vol.17
, pp. 929-930
-
-
Campbell, D.J.1
Koch, M.A.2
-
19
-
-
80052092702
-
Regulatory T cells: pursuing a germinal centre career
-
Papatriantafyllou M. Regulatory T cells: pursuing a germinal centre career. Nat Rev Immunol 2011, 11:572.
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 572
-
-
Papatriantafyllou, M.1
-
20
-
-
83755166410
-
Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses
-
Chang P., Barral P., Fitch J., Pratama A., Ma C., Kallies A., Hogan J., Cerundolo V., Tangye S., Bittman R., et al. Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses. Nat Immunol 2012, 13:35-43.
-
(2012)
Nat Immunol
, vol.13
, pp. 35-43
-
-
Chang, P.1
Barral, P.2
Fitch, J.3
Pratama, A.4
Ma, C.5
Kallies, A.6
Hogan, J.7
Cerundolo, V.8
Tangye, S.9
Bittman, R.10
-
21
-
-
79959352136
-
A fine romance: T follicular helper cells and B cells
-
King C. A fine romance: T follicular helper cells and B cells. Immunity 2011, 34:827-829.
-
(2011)
Immunity
, vol.34
, pp. 827-829
-
-
King, C.1
-
22
-
-
84859716676
-
Differentiation of germinal center B cells and follicular helper T cells as viewed by tracking Bcl6 expression dynamics
-
Okada T., Moriyama S., Kitano M. Differentiation of germinal center B cells and follicular helper T cells as viewed by tracking Bcl6 expression dynamics. Immunol Rev 2012, 247:120-132.
-
(2012)
Immunol Rev
, vol.247
, pp. 120-132
-
-
Okada, T.1
Moriyama, S.2
Kitano, M.3
-
23
-
-
80052649061
-
Cutting edge: distinct waves of BCL6 expression during T follicular helper cell development
-
Baumjohann D., Okada T., Ansel K.M. Cutting edge: distinct waves of BCL6 expression during T follicular helper cell development. J Immunol 2011, 187:2089-2092.
-
(2011)
J Immunol
, vol.187
, pp. 2089-2092
-
-
Baumjohann, D.1
Okada, T.2
Ansel, K.M.3
-
24
-
-
79959328032
-
Follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6
-
ICOS, Receptor Instructs T:
-
Choi Y.S., Kageyama R., Eto D., Escobar T.C., Johnston R.J., Monticelli L., Lao C., Crotty S: I.C.O.S., Receptor Instructs T. Follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6. Immunity 2011, 34:932-946.
-
(2011)
Immunity
, vol.34
, pp. 932-946
-
-
Choi, Y.S.1
Kageyama, R.2
Eto, D.3
Escobar, T.C.4
Johnston, R.J.5
Monticelli, L.6
Lao, C.7
Crotty, S.8
-
25
-
-
79959343565
-
Bcl6 protein expression shapes pre-germinal center B cell dynamics and follicular helper T cell heterogeneity
-
Kitano M., Moriyama S., Ando Y., Hikida M., Mori Y., Kurosaki T., Okada T. Bcl6 protein expression shapes pre-germinal center B cell dynamics and follicular helper T cell heterogeneity. Immunity 2011, 34:961-972.
-
(2011)
Immunity
, vol.34
, pp. 961-972
-
-
Kitano, M.1
Moriyama, S.2
Ando, Y.3
Hikida, M.4
Mori, Y.5
Kurosaki, T.6
Okada, T.7
-
26
-
-
79959342619
-
Germinal center B cell and T follicular helper cell development initiates in the interfollicular zone
-
Kerfoot S.M., Yaari G., Patel J.R., Johnson K.L., Gonzalez D.G., Kleinstein S.H., Haberman A.M. Germinal center B cell and T follicular helper cell development initiates in the interfollicular zone. Immunity 2011, 34:947-960.
-
(2011)
Immunity
, vol.34
, pp. 947-960
-
-
Kerfoot, S.M.1
Yaari, G.2
Patel, J.R.3
Johnson, K.L.4
Gonzalez, D.G.5
Kleinstein, S.H.6
Haberman, A.M.7
-
27
-
-
53649107278
-
SAP-controlled T-B cell interactions underlie germinal centre formation
-
Qi H., Cannons J., Klauschen F., Schwartzberg P., Germain R. SAP-controlled T-B cell interactions underlie germinal centre formation. Nature 2008, 455:764-769.
-
(2008)
Nature
, vol.455
, pp. 764-769
-
-
Qi, H.1
Cannons, J.2
Klauschen, F.3
Schwartzberg, P.4
Germain, R.5
-
28
-
-
79960342424
-
B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells
-
Lee S.K., Rigby R.J., Zotos D., Tsai L.M., Kawamoto S., Marshall J.L., Ramiscal R.R., Chan T.D., Gatto D., Brink R., et al. B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells. J Exp Med 2011, 208:1377-1388.
-
(2011)
J Exp Med
, vol.208
, pp. 1377-1388
-
-
Lee, S.K.1
Rigby, R.J.2
Zotos, D.3
Tsai, L.M.4
Kawamoto, S.5
Marshall, J.L.6
Ramiscal, R.R.7
Chan, T.D.8
Gatto, D.9
Brink, R.10
-
29
-
-
77953494012
-
BCL6 is critical for the development of a diverse primary B cell repertoire
-
Duy C., Yu J.J., Nahar R., Swaminathan S., Kweon S.M., Polo J.M., Valls E., Klemm L., Shojaee S., Cerchietti L., et al. BCL6 is critical for the development of a diverse primary B cell repertoire. J Exp Med 2010, 207:1209-1221.
-
(2010)
J Exp Med
, vol.207
, pp. 1209-1221
-
-
Duy, C.1
Yu, J.J.2
Nahar, R.3
Swaminathan, S.4
Kweon, S.M.5
Polo, J.M.6
Valls, E.7
Klemm, L.8
Shojaee, S.9
Cerchietti, L.10
-
30
-
-
80054093403
-
Pre-B cell receptor-mediated activation of BCL6 induces pre-B cell quiescence through transcriptional repression of MYC
-
Nahar R., Ramezani-Rad P., Mossner M., Duy C., Cerchietti L., Geng H., Dovat S., Jumaa H., Ye B.H., Melnick A., et al. Pre-B cell receptor-mediated activation of BCL6 induces pre-B cell quiescence through transcriptional repression of MYC. Blood 2011, 118:4174-4178.
-
(2011)
Blood
, vol.118
, pp. 4174-4178
-
-
Nahar, R.1
Ramezani-Rad, P.2
Mossner, M.3
Duy, C.4
Cerchietti, L.5
Geng, H.6
Dovat, S.7
Jumaa, H.8
Ye, B.H.9
Melnick, A.10
-
31
-
-
79956305728
-
+ acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition
-
+ acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition. Nature 2011, 473:384-388.
-
(2011)
Nature
, vol.473
, pp. 384-388
-
-
Duy, C.1
Hurtz, C.2
Shojaee, S.3
Cerchietti, L.4
Geng, H.5
Swaminathan, S.6
Klemm, L.7
Kweon, S.8
Nahar, R.9
Braig, M.10
-
32
-
-
84870007432
-
Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia
-
Geng H., Brennan S., Milne T.A., Chen W.Y., Li Y., Hurtz C., Kweon S.M., Zickl L., Shojaee S., Neuberg D., et al. Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia. Cancer Discov 2012, 2:1004-1023.
-
(2012)
Cancer Discov
, vol.2
, pp. 1004-1023
-
-
Geng, H.1
Brennan, S.2
Milne, T.A.3
Chen, W.Y.4
Li, Y.5
Hurtz, C.6
Kweon, S.M.7
Zickl, L.8
Shojaee, S.9
Neuberg, D.10
-
33
-
-
75649136214
-
Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation
-
Crotty S., Johnston R.J., Schoenberger S.P. Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation. Nat Immunol 2010, 11:114-120.
-
(2010)
Nat Immunol
, vol.11
, pp. 114-120
-
-
Crotty, S.1
Johnston, R.J.2
Schoenberger, S.P.3
-
35
-
-
0034278587
-
TH2 inflammation repressed by chemokines
-
Canfield S., Rothman P. TH2 inflammation repressed by chemokines. Nat Immunol 2000, 1:189-190.
-
(2000)
Nat Immunol
, vol.1
, pp. 189-190
-
-
Canfield, S.1
Rothman, P.2
-
36
-
-
84868530014
-
Bcl6 controls the Th2 inflammatory activity of regulatory T cells by repressing Gata3 function
-
Sawant D.V., Sehra S., Nguyen E.T., Jadhav R., Englert K., Shinnakasu R., Hangoc G., Broxmeyer H.E., Nakayama T., Perumal N.B., et al. Bcl6 controls the Th2 inflammatory activity of regulatory T cells by repressing Gata3 function. J Immunol 2012, 189:4759-4769.
-
(2012)
J Immunol
, vol.189
, pp. 4759-4769
-
-
Sawant, D.V.1
Sehra, S.2
Nguyen, E.T.3
Jadhav, R.4
Englert, K.5
Shinnakasu, R.6
Hangoc, G.7
Broxmeyer, H.E.8
Nakayama, T.9
Perumal, N.B.10
-
37
-
-
77952780554
-
Transcriptional repressor BCL6 controls Th17 responses by controlling gene expression in both T cells and macrophages
-
Mondal A., Sawant D., Dent A.L. Transcriptional repressor BCL6 controls Th17 responses by controlling gene expression in both T cells and macrophages. J Immunol 2010, 184:4123-4132.
-
(2010)
J Immunol
, vol.184
, pp. 4123-4132
-
-
Mondal, A.1
Sawant, D.2
Dent, A.L.3
-
38
-
-
78650652592
-
+ T suppressor cells
-
+ T suppressor cells. J Immunol 2010, 185:5714-5722.
-
(2010)
J Immunol
, vol.185
, pp. 5714-5722
-
-
Chang, C.C.1
Vlad, G.2
D'Agati, V.D.3
Liu, Z.4
Zhang, Q.Y.5
Witkowski, P.6
Torkamani, A.A.7
Stokes, M.B.8
Ho, E.K.9
Cortesini, R.10
-
39
-
-
0034278508
-
BCL-6 regulates chemokine gene transcription in macrophages
-
Toney L.M., Cattoretti G., Graf J.A., Merghoub T., Pandolfi P.P., Dalla-Favera R., Ye B.H., Dent A.L. BCL-6 regulates chemokine gene transcription in macrophages. Nat Immunol 2000, 1:214-220.
-
(2000)
Nat Immunol
, vol.1
, pp. 214-220
-
-
Toney, L.M.1
Cattoretti, G.2
Graf, J.A.3
Merghoub, T.4
Pandolfi, P.P.5
Dalla-Favera, R.6
Ye, B.H.7
Dent, A.L.8
-
40
-
-
78650210727
-
Bcl-6 and NF-{kappa}B cistromes mediate opposing regulation of the innate immune response
-
Barish G.D., Yu R.T., Karunasiri M., Ocampo C.B., Dixon J., Benner C., Dent A.L., Tangirala R.K., Evans R.M. Bcl-6 and NF-{kappa}B cistromes mediate opposing regulation of the innate immune response. Genes Dev 2010, 24:2760-2765.
-
(2010)
Genes Dev
, vol.24
, pp. 2760-2765
-
-
Barish, G.D.1
Yu, R.T.2
Karunasiri, M.3
Ocampo, C.B.4
Dixon, J.5
Benner, C.6
Dent, A.L.7
Tangirala, R.K.8
Evans, R.M.9
-
41
-
-
67049097382
-
The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL
-
Ci W., Polo J.M., Cerchietti L., Shaknovich R., Wang L., Yang S.N., Ye K., Farinha P., Horsman D.E., Gascoyne R.D., et al. The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL. Blood 2009, 113:5536-5548.
-
(2009)
Blood
, vol.113
, pp. 5536-5548
-
-
Ci, W.1
Polo, J.M.2
Cerchietti, L.3
Shaknovich, R.4
Wang, L.5
Yang, S.N.6
Ye, K.7
Farinha, P.8
Horsman, D.E.9
Gascoyne, R.D.10
-
42
-
-
84873710138
-
The Bcl6 target gene microRNA-21 promotes Th2 differentiation by a T cell intrinsic pathway
-
Sawant D.V., Wu H., Kaplan M.H., Dent A.L. The Bcl6 target gene microRNA-21 promotes Th2 differentiation by a T cell intrinsic pathway. Mol Immunol 2013, 54:435-442.
-
(2013)
Mol Immunol
, vol.54
, pp. 435-442
-
-
Sawant, D.V.1
Wu, H.2
Kaplan, M.H.3
Dent, A.L.4
-
43
-
-
84875416419
-
Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated by distinct biochemical mechanisms
-
Huang C., Hatzi K., Melnick A. Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated by distinct biochemical mechanisms. Nat Immunol 2013, 14:380-388.
-
(2013)
Nat Immunol
, vol.14
, pp. 380-388
-
-
Huang, C.1
Hatzi, K.2
Melnick, A.3
-
44
-
-
84859711533
-
Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation
-
Kroenke M.A., Eto D., Locci M., Cho M., Davidson T., Haddad E.K., Crotty S. Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation. J Immunol 2012, 188:3734-3744.
-
(2012)
J Immunol
, vol.188
, pp. 3734-3744
-
-
Kroenke, M.A.1
Eto, D.2
Locci, M.3
Cho, M.4
Davidson, T.5
Haddad, E.K.6
Crotty, S.7
-
45
-
-
79956201473
-
The lineage-defining factors T-bet and Bcl-6 collaborate to regulate Th1 gene expression patterns
-
Oestreich K.J., Huang A.C., Weinmann A.S. The lineage-defining factors T-bet and Bcl-6 collaborate to regulate Th1 gene expression patterns. J Exp Med 2011, 208:1001-1013.
-
(2011)
J Exp Med
, vol.208
, pp. 1001-1013
-
-
Oestreich, K.J.1
Huang, A.C.2
Weinmann, A.S.3
-
46
-
-
31344450346
-
Regulation of the germinal center gene program by interferon (IFN) regulatory factor 8/IFN consensus sequence-binding protein
-
Lee C.H., Melchers M., Wang H., Torrey T.A., Slota R., Qi C.F., Kim J.Y., Lugar P., Kong H.J., Farrington L., et al. Regulation of the germinal center gene program by interferon (IFN) regulatory factor 8/IFN consensus sequence-binding protein. J Exp Med 2006, 203:63-72.
-
(2006)
J Exp Med
, vol.203
, pp. 63-72
-
-
Lee, C.H.1
Melchers, M.2
Wang, H.3
Torrey, T.A.4
Slota, R.5
Qi, C.F.6
Kim, J.Y.7
Lugar, P.8
Kong, H.J.9
Farrington, L.10
-
47
-
-
84860330649
-
P110δ phosphoinositide 3-kinase represses IgE switch by potentiating BCL6 expression
-
Zhang T.T., Makondo K.J., Marshall A.J. p110δ phosphoinositide 3-kinase represses IgE switch by potentiating BCL6 expression. J Immunol 2012, 188:3700-3708.
-
(2012)
J Immunol
, vol.188
, pp. 3700-3708
-
-
Zhang, T.T.1
Makondo, K.J.2
Marshall, A.J.3
-
48
-
-
77149142640
-
IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism
-
Zotos D., Coquet J.M., Zhang Y., Light A., D'Costa K., Kallies A., Corcoran L.M., Godfrey D.I., Toellner K.M., Smyth M.J., et al. IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism. J Exp Med 2010, 207:365-378.
-
(2010)
J Exp Med
, vol.207
, pp. 365-378
-
-
Zotos, D.1
Coquet, J.M.2
Zhang, Y.3
Light, A.4
D'Costa, K.5
Kallies, A.6
Corcoran, L.M.7
Godfrey, D.I.8
Toellner, K.M.9
Smyth, M.J.10
-
49
-
-
77956207524
-
In vivo regulation of Bcl6 and T follicular helper cell development
-
Poholek A.C., Hansen K., Hernandez S.G., Eto D., Chandele A., Weinstein J.S., Dong X., Odegard J.M., Kaech S.M., Dent A.L., et al. In vivo regulation of Bcl6 and T follicular helper cell development. J Immunol 2010, 185:313-326.
-
(2010)
J Immunol
, vol.185
, pp. 313-326
-
-
Poholek, A.C.1
Hansen, K.2
Hernandez, S.G.3
Eto, D.4
Chandele, A.5
Weinstein, J.S.6
Dong, X.7
Odegard, J.M.8
Kaech, S.M.9
Dent, A.L.10
-
50
-
-
84870283741
-
B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1
-
Karnowski A., Chevrier S., Belz G.T., Mount A., Emslie D., D'Costa K., Tarlinton D.M., Kallies A., Corcoran L.M. B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1. J Exp Med 2012, 209:2049-2064.
-
(2012)
J Exp Med
, vol.209
, pp. 2049-2064
-
-
Karnowski, A.1
Chevrier, S.2
Belz, G.T.3
Mount, A.4
Emslie, D.5
D'Costa, K.6
Tarlinton, D.M.7
Kallies, A.8
Corcoran, L.M.9
-
51
-
-
78651285229
-
Follicular dendritic cell-induced microRNA-mediated upregulation of PRDM1 and downregulation of BCL-6 in non-Hodgkin's B-cell lymphomas
-
Lin J., Lwin T., Zhao J.J., Tam W., Choi Y.S., Moscinski L.C., Dalton W.S., Sotomayor E.M., Wright K.L., Tao J. Follicular dendritic cell-induced microRNA-mediated upregulation of PRDM1 and downregulation of BCL-6 in non-Hodgkin's B-cell lymphomas. Leukemia 2011, 25:145-152.
-
(2011)
Leukemia
, vol.25
, pp. 145-152
-
-
Lin, J.1
Lwin, T.2
Zhao, J.J.3
Tam, W.4
Choi, Y.S.5
Moscinski, L.C.6
Dalton, W.S.7
Sotomayor, E.M.8
Wright, K.L.9
Tao, J.10
-
52
-
-
79956079578
-
Germinal center B and follicular helper T cells: siblings, cousins or just good friends?
-
Nutt S.L., Tarlinton D.M. Germinal center B and follicular helper T cells: siblings, cousins or just good friends?. Nat Immunol 2011, 131:472-477.
-
(2011)
Nat Immunol
, vol.131
, pp. 472-477
-
-
Nutt, S.L.1
Tarlinton, D.M.2
-
53
-
-
84861872906
-
Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation
-
Bollig N., Brustle A., Kellner K., Ackermann W., Abass E., Raifer H., Camara B., Brendel C., Giel G., Bothur E., et al. Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation. Proc Natl Acad Sci U S A 2012, 109:8664-8669.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 8664-8669
-
-
Bollig, N.1
Brustle, A.2
Kellner, K.3
Ackermann, W.4
Abass, E.5
Raifer, H.6
Camara, B.7
Brendel, C.8
Giel, G.9
Bothur, E.10
-
54
-
-
84856394411
-
Interferons directly down-regulate BCL-6 in primary and transformed germinal center B cells: differential regulation in B cell lines derived from endemic or sporadic Burkitt's lymphoma
-
Salamon D., Adori M., He M., Bönelt P., Severinson E., Kis L.L., Wu L., Ujvari D., Leveau B., Nagy N., Type I., et al. interferons directly down-regulate BCL-6 in primary and transformed germinal center B cells: differential regulation in B cell lines derived from endemic or sporadic Burkitt's lymphoma. Cytokine 2012, 57:360-371.
-
(2012)
Cytokine
, vol.57
, pp. 360-371
-
-
Salamon, D.1
Adori, M.2
He, M.3
Bönelt, P.4
Severinson, E.5
Kis, L.L.6
Wu, L.7
Ujvari, D.8
Leveau, B.9
Nagy, N.10
Type, I.11
-
55
-
-
33846187999
-
STAT5 represses BCL6 expression by binding to a regulatory region frequently mutated in lymphomas
-
Walker S.R., Nelson E.A., Frank D.A. STAT5 represses BCL6 expression by binding to a regulatory region frequently mutated in lymphomas. Oncogene 2007, 26:224-233.
-
(2007)
Oncogene
, vol.26
, pp. 224-233
-
-
Walker, S.R.1
Nelson, E.A.2
Frank, D.A.3
-
56
-
-
84863116170
-
STAT5 is a potent negative regulator of TFH cell differentiation
-
Johnston R.J., Choi Y.S., Diamond J.A., Yang J.A., Crotty S. STAT5 is a potent negative regulator of TFH cell differentiation. J Exp Med 2012, 209:243-250.
-
(2012)
J Exp Med
, vol.209
, pp. 243-250
-
-
Johnston, R.J.1
Choi, Y.S.2
Diamond, J.A.3
Yang, J.A.4
Crotty, S.5
-
57
-
-
84859487740
-
STAT5 protein negatively regulates T follicular helper (Tfh) cell generation and function
-
Nurieva R.I., Podd A., Chen Y., Alekseev A.M., Yu M., Qi X., Huang H., Wen R., Wang J., Li H.S., et al. STAT5 protein negatively regulates T follicular helper (Tfh) cell generation and function. J Biol Chem 2012, 287:11234-11239.
-
(2012)
J Biol Chem
, vol.287
, pp. 11234-11239
-
-
Nurieva, R.I.1
Podd, A.2
Chen, Y.3
Alekseev, A.M.4
Yu, M.5
Qi, X.6
Huang, H.7
Wen, R.8
Wang, J.9
Li, H.S.10
-
58
-
-
84861423126
-
Interleukin-2 inhibits germinal center formation by limiting T follicular helper cell differentiation
-
Ballesteros-Tato A., León B., Graf B.A., Moquin A., Adams P.S., Lund F.E., Randall T.D. Interleukin-2 inhibits germinal center formation by limiting T follicular helper cell differentiation. Immunity 2012, 36:847-856.
-
(2012)
Immunity
, vol.36
, pp. 847-856
-
-
Ballesteros-Tato, A.1
León, B.2
Graf, B.A.3
Moquin, A.4
Adams, P.S.5
Lund, F.E.6
Randall, T.D.7
-
59
-
-
0036898253
-
Acetylation inactivates the transcriptional repressor BCL6
-
Bereshchenko O.R., Gu W., Dalla-Favera R. Acetylation inactivates the transcriptional repressor BCL6. Nat Genet 2002, 32:606-613.
-
(2002)
Nat Genet
, vol.32
, pp. 606-613
-
-
Bereshchenko, O.R.1
Gu, W.2
Dalla-Favera, R.3
-
60
-
-
34548706562
-
Genotoxic stress regulates expression of the proto-oncogene Bcl6 in germinal center B cells
-
Phan R., Saito M., Kitagawa Y., Means A., Dalla-Favera R. Genotoxic stress regulates expression of the proto-oncogene Bcl6 in germinal center B cells. Nat Immunol 2007, 8:1132-1139.
-
(2007)
Nat Immunol
, vol.8
, pp. 1132-1139
-
-
Phan, R.1
Saito, M.2
Kitagawa, Y.3
Means, A.4
Dalla-Favera, R.5
-
61
-
-
0032128002
-
Antigen receptor signaling induces MAP kinase-mediated phosphorylation and degradation of the BCL-6 transcription factor
-
Niu H., Ye B., Dalla-Favera R. Antigen receptor signaling induces MAP kinase-mediated phosphorylation and degradation of the BCL-6 transcription factor. Genes Dev 1998, 12:1953-1961.
-
(1998)
Genes Dev
, vol.12
, pp. 1953-1961
-
-
Niu, H.1
Ye, B.2
Dalla-Favera, R.3
-
62
-
-
84855447125
-
FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas
-
Duan S., Cermak L., Pagan J.K., Rossi M., Martinengo C., di Celle P.F., Chapuy B., Shipp M., Chiarle R., Pagano M. FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas. Nature 2011, 481:90-93.
-
(2011)
Nature
, vol.481
, pp. 90-93
-
-
Duan, S.1
Cermak, L.2
Pagan, J.K.3
Rossi, M.4
Martinengo, C.5
di Celle, P.F.6
Chapuy, B.7
Shipp, M.8
Chiarle, R.9
Pagano, M.10
-
63
-
-
84857806053
-
JAB1 is essential for B cell development and germinal center formation and inversely regulates Fas ligand and Bcl6 expression
-
Sitte S., Glasner J., Jellusova J., Weisel F., Panattoni M., Pardi R., Gessner A JAB1 is essential for B cell development and germinal center formation and inversely regulates Fas ligand and Bcl6 expression. J Immunol 2012, 1-11.
-
(2012)
J Immunol
, vol.1-11
-
-
Sitte, S.1
Glasner, J.2
Jellusova, J.3
Weisel, F.4
Panattoni, M.5
Pardi, R.6
Gessner, A.7
-
64
-
-
71549121697
-
A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6-dependent B cell lymphomas
-
Cerchietti L.C., Lopes E.C., Yang S.N., Hatzi K., Bunting K.L., Tsikitas L.A., Mallik A., Robles A.I., Walling J., Varticovski L., et al. A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6-dependent B cell lymphomas. Nat Med 2009, 15:1369-1376.
-
(2009)
Nat Med
, vol.15
, pp. 1369-1376
-
-
Cerchietti, L.C.1
Lopes, E.C.2
Yang, S.N.3
Hatzi, K.4
Bunting, K.L.5
Tsikitas, L.A.6
Mallik, A.7
Robles, A.I.8
Walling, J.9
Varticovski, L.10
-
65
-
-
34250762588
-
Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR
-
Ranuncolo S., Polo J., Dierov J., Singer M., Kuo T., Greally J., Green R., Carroll M., Melnick A. Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR. Nat Immunol 2007, 8:705-714.
-
(2007)
Nat Immunol
, vol.8
, pp. 705-714
-
-
Ranuncolo, S.1
Polo, J.2
Dierov, J.3
Singer, M.4
Kuo, T.5
Greally, J.6
Green, R.7
Carroll, M.8
Melnick, A.9
-
66
-
-
77950486830
-
A small-molecule inhibitor of BCL6 kills DLBCL cells in vitro and in vivo
-
Cerchietti L.C., Ghetu A.F., Zhu X., Da Silva G.F., Zhong S., Matthews M., Bunting K.L., Polo J.M., Farès C., Arrowsmith C.H., et al. A small-molecule inhibitor of BCL6 kills DLBCL cells in vitro and in vivo. Cancer Cell 2010, 17:400-411.
-
(2010)
Cancer Cell
, vol.17
, pp. 400-411
-
-
Cerchietti, L.C.1
Ghetu, A.F.2
Zhu, X.3
Da Silva, G.F.4
Zhong, S.5
Matthews, M.6
Bunting, K.L.7
Polo, J.M.8
Farès, C.9
Arrowsmith, C.H.10
-
67
-
-
80052029516
-
Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma
-
Morin R.D., Mendez-Lago M., Mungall A.J., Goya R., Mungall K.L., Corbett R.D., Johnson N.A., Severson T.M., Chiu R., Field M., et al. Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma. Nature 2011, 476:298-303.
-
(2011)
Nature
, vol.476
, pp. 298-303
-
-
Morin, R.D.1
Mendez-Lago, M.2
Mungall, A.J.3
Goya, R.4
Mungall, K.L.5
Corbett, R.D.6
Johnson, N.A.7
Severson, T.M.8
Chiu, R.9
Field, M.10
-
68
-
-
80052269038
-
Analysis of the coding genome of diffuse large B-cell lymphoma
-
Pasqualucci L., Trifonov V., Fabbri G., Ma J., Rossi D., Chiarenza A., Wells V.A., Grunn A., Messina M., Elliot O., et al. Analysis of the coding genome of diffuse large B-cell lymphoma. Nat Genet 2011, 43:830-837.
-
(2011)
Nat Genet
, vol.43
, pp. 830-837
-
-
Pasqualucci, L.1
Trifonov, V.2
Fabbri, G.3
Ma, J.4
Rossi, D.5
Chiarenza, A.6
Wells, V.A.7
Grunn, A.8
Messina, M.9
Elliot, O.10
-
69
-
-
84857942952
-
Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing
-
Lohr J.G., Stojanov P., Lawrence M.S., Auclair D., Chapuy B., Sougnez C., Cruz-Gordillo P., Knoechel B., Asmann Y.W., Slager S.L., et al. Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing. Proc Natl Acad Sci U S A 2012, 109:3879-3884.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 3879-3884
-
-
Lohr, J.G.1
Stojanov, P.2
Lawrence, M.S.3
Auclair, D.4
Chapuy, B.5
Sougnez, C.6
Cruz-Gordillo, P.7
Knoechel, B.8
Asmann, Y.W.9
Slager, S.L.10
-
70
-
-
67650506692
-
BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma
-
Saito M., Novak U., Piovan E., Basso K., Sumazin P., Schneider C., Crespo M., Shen Q., Bhagat G., Califano A., et al. BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma. Proc Natl Acad Sci U S A 2009, 106:11294-11299.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 11294-11299
-
-
Saito, M.1
Novak, U.2
Piovan, E.3
Basso, K.4
Sumazin, P.5
Schneider, C.6
Crespo, M.7
Shen, Q.8
Bhagat, G.9
Califano, A.10
-
72
-
-
78649826886
-
BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy
-
Cerchietti L.C., Hatzi K., Caldas-Lopes E., Yang S.N., Figueroa M.E., Morin R.D., Hirst M., Mendez L., Shaknovich R., Cole P.A., et al. BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy. J Clin Invest 2010, 120:4569-4582.
-
(2010)
J Clin Invest
, vol.120
, pp. 4569-4582
-
-
Cerchietti, L.C.1
Hatzi, K.2
Caldas-Lopes, E.3
Yang, S.N.4
Figueroa, M.E.5
Morin, R.D.6
Hirst, M.7
Mendez, L.8
Shaknovich, R.9
Cole, P.A.10
-
73
-
-
79952430906
-
Inactivating mutations of acetyltransferase genes in B-cell lymphoma
-
Pasqualucci L., Dominguez-Sola D., Chiarenza A., Fabbri G., Grunn A., Trifonov V., Kasper L.H., Lerach S., Tang H., Ma J., et al. Inactivating mutations of acetyltransferase genes in B-cell lymphoma. Nature 2011, 471:189-195.
-
(2011)
Nature
, vol.471
, pp. 189-195
-
-
Pasqualucci, L.1
Dominguez-Sola, D.2
Chiarenza, A.3
Fabbri, G.4
Grunn, A.5
Trifonov, V.6
Kasper, L.H.7
Lerach, S.8
Tang, H.9
Ma, J.10
-
74
-
-
33847406330
-
+ subtypes
-
+ subtypes. Blood 2007, 109:2156-2164.
-
(2007)
Blood
, vol.109
, pp. 2156-2164
-
-
Lamant, L.1
de Reynies, A.2
Duplantier, M.M.3
Rickman, D.S.4
Sabourdy, F.5
Giuriato, S.6
Brugieres, L.7
Gaulard, P.8
Espinos, E.9
Delsol, G.10
-
75
-
-
34249652415
-
The gene expression profile of nodal peripheral T-cell lymphoma demonstrates a molecular link between angioimmunoblastic T-cell lymphoma (AITL) and follicular helper T (TFH) cells
-
de Leval L., Rickman D.S., Thielen C., Reynies A., Huang Y.L., Delsol G., Lamant L., Leroy K., Brière J., Molina T., et al. The gene expression profile of nodal peripheral T-cell lymphoma demonstrates a molecular link between angioimmunoblastic T-cell lymphoma (AITL) and follicular helper T (TFH) cells. Blood 2007, 109:4952-4963.
-
(2007)
Blood
, vol.109
, pp. 4952-4963
-
-
de Leval, L.1
Rickman, D.S.2
Thielen, C.3
Reynies, A.4
Huang, Y.L.5
Delsol, G.6
Lamant, L.7
Leroy, K.8
Brière, J.9
Molina, T.10
-
76
-
-
36348982897
-
Gene expression analysis of angioimmunoblastic lymphoma indicates derivation from T follicular helper cells and vascular endothelial growth factor deregulation
-
Piccaluga P.P., Agostinelli C., Califano A., Carbone A., Fantoni L., Ferrari S., Gazzola A., Gloghini A., Righi S., Rossi M., et al. Gene expression analysis of angioimmunoblastic lymphoma indicates derivation from T follicular helper cells and vascular endothelial growth factor deregulation. Cancer Res 2007, 67:10703-10710.
-
(2007)
Cancer Res
, vol.67
, pp. 10703-10710
-
-
Piccaluga, P.P.1
Agostinelli, C.2
Califano, A.3
Carbone, A.4
Fantoni, L.5
Ferrari, S.6
Gazzola, A.7
Gloghini, A.8
Righi, S.9
Rossi, M.10
-
77
-
-
84355161676
-
Expression of programmed death-1 in primary cutaneous CD4-positive small/medium-sized pleomorphic T-cell lymphoma, cutaneous pseudo-T-cell lymphoma, and other types of cutaneous T-cell lymphoma
-
Cetinözman F., Jansen P.M., Willemze R. Expression of programmed death-1 in primary cutaneous CD4-positive small/medium-sized pleomorphic T-cell lymphoma, cutaneous pseudo-T-cell lymphoma, and other types of cutaneous T-cell lymphoma. Am J Surg Pathol 2012, 36:109-116.
-
(2012)
Am J Surg Pathol
, vol.36
, pp. 109-116
-
-
Cetinözman, F.1
Jansen, P.M.2
Willemze, R.3
-
78
-
-
83055181891
-
The four types of Tregs in malignant lymphomas
-
Wang J., Ke X.Y. The four types of Tregs in malignant lymphomas. J Hematol Oncol 2011, 4:50.
-
(2011)
J Hematol Oncol
, vol.4
, pp. 50
-
-
Wang, J.1
Ke, X.Y.2
-
79
-
-
65349119454
-
A peptomimetic inhibitor of BCL6 with potent anti-lymphoma effects in vitro and in vivo
-
Cerchietti L.C., Yang S.N., Shaknovich R., Hatzi K., Polo J.M., Chadburn A., Dowdy S.F., Melnick A. A peptomimetic inhibitor of BCL6 with potent anti-lymphoma effects in vitro and in vivo. Blood 2008, 113:3397-3405.
-
(2008)
Blood
, vol.113
, pp. 3397-3405
-
-
Cerchietti, L.C.1
Yang, S.N.2
Shaknovich, R.3
Hatzi, K.4
Polo, J.M.5
Chadburn, A.6
Dowdy, S.F.7
Melnick, A.8
|